HUP0301403A3 - A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride and it's use - Google Patents

A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride and it's use

Info

Publication number
HUP0301403A3
HUP0301403A3 HU0301403A HUP0301403A HUP0301403A3 HU P0301403 A3 HUP0301403 A3 HU P0301403A3 HU 0301403 A HU0301403 A HU 0301403A HU P0301403 A HUP0301403 A HU P0301403A HU P0301403 A3 HUP0301403 A3 HU P0301403A3
Authority
HU
Hungary
Prior art keywords
piperidin
benzo
methoxyphenyl
phenoxy
ethoxy
Prior art date
Application number
HU0301403A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HUP0301403A2 publication Critical patent/HUP0301403A2/hu
Publication of HUP0301403A3 publication Critical patent/HUP0301403A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
HU0301403A 2000-10-20 2001-10-18 A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride and it's use HUP0301403A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24225200P 2000-10-20 2000-10-20
PCT/US2001/027773 WO2002034741A2 (en) 2000-10-20 2001-10-18 A NOVEL CRYSTALLINE FORM OF 6-HYDROXY-3-(4-[2-(PIPERIDIN-1-YL)ETHOXY]PHENOXY)-2-(4-METHOXYPHENYL)BENZO[b]THIOPHENE HYDROCHLORIDE

Publications (2)

Publication Number Publication Date
HUP0301403A2 HUP0301403A2 (hu) 2003-10-28
HUP0301403A3 true HUP0301403A3 (en) 2009-05-28

Family

ID=22914051

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301403A HUP0301403A3 (en) 2000-10-20 2001-10-18 A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride and it's use

Country Status (26)

Country Link
US (1) US20040014672A1 (hu)
EP (1) EP1328521A2 (hu)
JP (1) JP2004512333A (hu)
KR (1) KR20030037690A (hu)
CN (1) CN1268624C (hu)
AR (1) AR035355A1 (hu)
AU (1) AU2002214534A1 (hu)
BR (1) BR0114792A (hu)
CA (1) CA2426007A1 (hu)
CZ (1) CZ20031098A3 (hu)
EA (1) EA005116B1 (hu)
EC (1) ECSP034560A (hu)
HK (1) HK1061857A1 (hu)
HR (1) HRP20030296A2 (hu)
HU (1) HUP0301403A3 (hu)
IL (1) IL155487A0 (hu)
MX (1) MXPA03003432A (hu)
MY (1) MY125009A (hu)
NO (1) NO20031753L (hu)
NZ (1) NZ525364A (hu)
PE (1) PE20020588A1 (hu)
PL (1) PL360946A1 (hu)
SK (1) SK4902003A3 (hu)
UA (1) UA76124C2 (hu)
WO (1) WO2002034741A2 (hu)
ZA (1) ZA200303061B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2371549T3 (es) * 2003-10-10 2012-01-05 Synthon B.V. Montelukast en estado sólido.
AU2005275185B2 (en) * 2004-07-22 2011-06-23 Eli Lilly And Company A crystalline variable hydrate of (S)-6-(4-(2-((3-(9H-carbazol-4-yloxy)-2-hydroxypropyl)amino)-2-methylpropyl)phenoxy)-3-pyridinecarbox amide hemisuccinate salt
US20110251143A1 (en) * 2007-12-19 2011-10-13 Spectrum Pharmaceuticals, Inc. Stable elsamitrucin salt formulations
EP2305238B1 (en) 2009-09-25 2011-12-14 Iasomai aktiebolag N-acetyl-L-cysteine for the treatment of endometriosis
PL236889B1 (pl) * 2017-10-03 2021-02-22 Univ Warszawski Medyczny Nowa forma krystaliczna bezwodnego 17-β-estradiolu, sposób jej otrzymywania oraz kompozycja farmaceutyczna zawierająca nową formę krystaliczną bezwodnego 17-β-estradiolu i jej zastosowanie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT729956E (pt) * 1995-02-28 2002-03-28 Lilly Co Eli Compostos intermediarios formulacoes e metodos de benzotiofeno
ZA982877B (en) * 1997-04-09 1999-10-04 Lilly Co Eli Treatment of central nervous system disorders with selective estrogen receptor modulators.
AU6335600A (en) * 1999-07-29 2001-02-19 Eli Lilly And Company A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-metho yphenyl)benzo[b]thiophene hydrochloride
ATE251151T1 (de) * 1999-07-29 2003-10-15 Lilly Co Eli Eine kristalline form von 6-hydroxy-3-(4-(2- (piperidin-1-yl)ethoxy)phenoxy)-2-(4- methoxyphenyl)benzo(b)thiophen-hydrochlorid

Also Published As

Publication number Publication date
EA200300491A1 (ru) 2003-08-28
JP2004512333A (ja) 2004-04-22
WO2002034741A3 (en) 2003-01-03
HRP20030296A2 (en) 2003-06-30
CZ20031098A3 (cs) 2003-08-13
IL155487A0 (en) 2003-11-23
KR20030037690A (ko) 2003-05-14
ECSP034560A (es) 2003-06-25
CN1469872A (zh) 2004-01-21
BR0114792A (pt) 2003-08-12
SK4902003A3 (en) 2003-10-07
NO20031753D0 (no) 2003-04-15
HK1061857A1 (en) 2004-10-08
PE20020588A1 (es) 2002-07-06
ZA200303061B (en) 2004-07-19
MY125009A (en) 2006-07-31
NZ525364A (en) 2005-09-30
NO20031753L (no) 2003-04-15
EP1328521A2 (en) 2003-07-23
UA76124C2 (en) 2006-07-17
WO2002034741A2 (en) 2002-05-02
EA005116B1 (ru) 2004-10-28
AU2002214534A1 (en) 2002-05-06
PL360946A1 (en) 2004-09-20
CN1268624C (zh) 2006-08-09
HUP0301403A2 (hu) 2003-10-28
AR035355A1 (es) 2004-05-12
CA2426007A1 (en) 2002-05-02
MXPA03003432A (es) 2003-08-07
US20040014672A1 (en) 2004-01-22

Similar Documents

Publication Publication Date Title
IL137552A0 (en) A NOVEL CRYSTALLINE FORM OF 6-HYDROXY-3-(4-[2-(PIPERIDIN-1-YL) ETHOXY]PHENOXY)-2-(4-METHOXYPHENYL) BENZO[b]THIOPHENE HYDROCHLORIDE
GB0018641D0 (en) A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[ b]thiophene hydrochloride
HUP0301403A3 (en) A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride and it's use
IL152699A0 (en) STABILIZED FORMULATIONS OF 6-HYDROXY-3-(4-[2-(PIPERIDIN-1-YL)ETHOXY]PHENOXY)-2-(4-METHOXYPHENYL) BENZO [b] THIOPHENE AND SALTS THEREOF
CY2344B1 (en) A novel crystalline form of 6-hydroxy-3-(4-(2-(piperidin-1-yl) ethoxy) phenoxy)-2-(4-methoxyphenyl) benzo (b) thiphene hydrochloride.
ZA200003838B (en) A novel chrystalline form of 6-hydroxy-3-(4-[2-)piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride.
TJ20000620A (en) A novel crystalline form of 6-hydroxy-3-(4-Ä2-(piperidin-1-yl) ethoxy Ü phenoxy) - 2 - (4-methanoxyphenyl) benzo ÄbÜ thiophene hidrochloride
TJ398B (en) A novel crystalline form of 6-hydroxy -3-(4-Ä2-(piperidin-1-yl) ethoxyÜ-phenoxy) -2-(4-methoxyphenyl) benzo ÄbÜ thiophene hydrochloride.

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees