ECSP034560A - UNA NUEVA FORMA CRISTALINA DE CLORHIDRATO DE 6-HIDROXI-3-(4-(2-(PIPERIDIN-1-IL)ETOXI)FENOXI)-2-(4-METOXIFENIL) BENZO (b) TIOFENO - Google Patents

UNA NUEVA FORMA CRISTALINA DE CLORHIDRATO DE 6-HIDROXI-3-(4-(2-(PIPERIDIN-1-IL)ETOXI)FENOXI)-2-(4-METOXIFENIL) BENZO (b) TIOFENO

Info

Publication number
ECSP034560A
ECSP034560A EC2003004560A ECSP034560A ECSP034560A EC SP034560 A ECSP034560 A EC SP034560A EC 2003004560 A EC2003004560 A EC 2003004560A EC SP034560 A ECSP034560 A EC SP034560A EC SP034560 A ECSP034560 A EC SP034560A
Authority
EC
Ecuador
Prior art keywords
piperidin
benzo
phenoxi
etoxi
metoxyphenyl
Prior art date
Application number
EC2003004560A
Other languages
English (en)
Inventor
Wayne Douglas Luke
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ECSP034560A publication Critical patent/ECSP034560A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L a presente invención se refiere a un clorhidrato de 6-hidroxi-3(4-(2-(piperidin-1-il) etoxi)fenoxi)-2-(4-metoxifenil)benzo(b) tiofeno cristalino anhidro no solvatado (F-V) que tiene un aspecto de difracción de rayos X que comprende, al menos, uno de los siguientes picos:7,3+0,2,15,5+0,2,15,9+0,2y 17,6+0,2 en 20 cuando de una fuente de radiación de cobre (=1,54056 A)
EC2003004560A 2000-10-20 2003-04-16 UNA NUEVA FORMA CRISTALINA DE CLORHIDRATO DE 6-HIDROXI-3-(4-(2-(PIPERIDIN-1-IL)ETOXI)FENOXI)-2-(4-METOXIFENIL) BENZO (b) TIOFENO ECSP034560A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24225200P 2000-10-20 2000-10-20

Publications (1)

Publication Number Publication Date
ECSP034560A true ECSP034560A (es) 2003-06-25

Family

ID=22914051

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2003004560A ECSP034560A (es) 2000-10-20 2003-04-16 UNA NUEVA FORMA CRISTALINA DE CLORHIDRATO DE 6-HIDROXI-3-(4-(2-(PIPERIDIN-1-IL)ETOXI)FENOXI)-2-(4-METOXIFENIL) BENZO (b) TIOFENO

Country Status (26)

Country Link
US (1) US20040014672A1 (es)
EP (1) EP1328521A2 (es)
JP (1) JP2004512333A (es)
KR (1) KR20030037690A (es)
CN (1) CN1268624C (es)
AR (1) AR035355A1 (es)
AU (1) AU2002214534A1 (es)
BR (1) BR0114792A (es)
CA (1) CA2426007A1 (es)
CZ (1) CZ20031098A3 (es)
EA (1) EA005116B1 (es)
EC (1) ECSP034560A (es)
HK (1) HK1061857A1 (es)
HR (1) HRP20030296A2 (es)
HU (1) HUP0301403A3 (es)
IL (1) IL155487A0 (es)
MX (1) MXPA03003432A (es)
MY (1) MY125009A (es)
NO (1) NO20031753L (es)
NZ (1) NZ525364A (es)
PE (1) PE20020588A1 (es)
PL (1) PL360946A1 (es)
SK (1) SK4902003A3 (es)
UA (1) UA76124C2 (es)
WO (1) WO2002034741A2 (es)
ZA (1) ZA200303061B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2541994A1 (en) * 2003-10-10 2005-05-06 Arjanne Overeem Solid-state montelukast
JP4922163B2 (ja) * 2004-07-22 2012-04-25 イーライ リリー アンド カンパニー （ｓ）−６−（４−（２−（（３−（９ｈ−カルバゾール−４−イルオキシ）−２−ヒドロキシプロピル）アミノ）−２−メチルプロピル）フェノキシ）−３−ピリジンカルボキサミドヘミコハク酸塩の結晶質の不定比水和物
EP2222276A1 (en) * 2007-12-19 2010-09-01 Spectrum Pharmaceuticals, Inc. Stable elsamitrucin salt formulations
EP2305238B1 (en) 2009-09-25 2011-12-14 Iasomai aktiebolag N-acetyl-L-cysteine for the treatment of endometriosis
PL236889B1 (pl) * 2017-10-03 2021-02-22 Univ Warszawski Medyczny Nowa forma krystaliczna bezwodnego 17-β-estradiolu, sposób jej otrzymywania oraz kompozycja farmaceutyczna zawierająca nową formę krystaliczną bezwodnego 17-β-estradiolu i jej zastosowanie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3989569B2 (ja) * 1995-02-28 2007-10-10 イーライ リリー アンド カンパニー ベンゾチオフェン化合物、中間体、組成物および方法
ZA982877B (en) * 1997-04-09 1999-10-04 Lilly Co Eli Treatment of central nervous system disorders with selective estrogen receptor modulators.
AU6335600A (en) * 1999-07-29 2001-02-19 Eli Lilly And Company A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-metho yphenyl)benzo[b]thiophene hydrochloride
EP1204655B1 (en) * 1999-07-29 2003-10-01 Eli Lilly And Company A crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy] phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride

Also Published As

Publication number Publication date
HUP0301403A3 (en) 2009-05-28
CN1268624C (zh) 2006-08-09
EA200300491A1 (ru) 2003-08-28
MXPA03003432A (es) 2003-08-07
BR0114792A (pt) 2003-08-12
SK4902003A3 (en) 2003-10-07
JP2004512333A (ja) 2004-04-22
CN1469872A (zh) 2004-01-21
EP1328521A2 (en) 2003-07-23
HUP0301403A2 (hu) 2003-10-28
NO20031753D0 (no) 2003-04-15
HRP20030296A2 (en) 2003-06-30
UA76124C2 (en) 2006-07-17
AR035355A1 (es) 2004-05-12
HK1061857A1 (en) 2004-10-08
MY125009A (en) 2006-07-31
PE20020588A1 (es) 2002-07-06
KR20030037690A (ko) 2003-05-14
NZ525364A (en) 2005-09-30
CZ20031098A3 (cs) 2003-08-13
PL360946A1 (en) 2004-09-20
WO2002034741A3 (en) 2003-01-03
NO20031753L (no) 2003-04-15
AU2002214534A1 (en) 2002-05-06
EA005116B1 (ru) 2004-10-28
ZA200303061B (en) 2004-07-19
WO2002034741A2 (en) 2002-05-02
IL155487A0 (en) 2003-11-23
US20040014672A1 (en) 2004-01-22
CA2426007A1 (en) 2002-05-02

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