HUP0301351A3 - Use of substituted dipeptides as growth hormone secretagogues, process for their preparation and pharmaceutical compositions containing them - Google Patents
Use of substituted dipeptides as growth hormone secretagogues, process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- HUP0301351A3 HUP0301351A3 HU0301351A HUP0301351A HUP0301351A3 HU P0301351 A3 HUP0301351 A3 HU P0301351A3 HU 0301351 A HU0301351 A HU 0301351A HU P0301351 A HUP0301351 A HU P0301351A HU P0301351 A3 HUP0301351 A3 HU P0301351A3
- Authority
- HU
- Hungary
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- growth hormone
- hormone secretagogues
- Prior art date
Links
- 108010016626 Dipeptides Proteins 0.000 title 1
- 239000003324 growth hormone secretagogue Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24045600P | 2000-10-13 | 2000-10-13 | |
| PCT/US2001/027756 WO2002032888A1 (en) | 2000-10-13 | 2001-10-09 | Substituted dipeptides as growth hormone secretagogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0301351A2 HUP0301351A2 (hu) | 2003-11-28 |
| HUP0301351A3 true HUP0301351A3 (en) | 2007-05-29 |
Family
ID=22906598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0301351A HUP0301351A3 (en) | 2000-10-13 | 2001-10-09 | Use of substituted dipeptides as growth hormone secretagogues, process for their preparation and pharmaceutical compositions containing them |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1326851B1 (hu) |
| JP (1) | JP2004511552A (hu) |
| KR (1) | KR20030042014A (hu) |
| CN (1) | CN1469871A (hu) |
| AT (1) | ATE270280T1 (hu) |
| AU (2) | AU1121902A (hu) |
| BR (1) | BR0114630A (hu) |
| CA (1) | CA2419388A1 (hu) |
| CZ (1) | CZ20031029A3 (hu) |
| DE (1) | DE60104141T2 (hu) |
| DZ (1) | DZ3482A1 (hu) |
| EA (1) | EA006102B1 (hu) |
| EC (1) | ECSP034551A (hu) |
| ES (1) | ES2223926T3 (hu) |
| HK (1) | HK1058194A1 (hu) |
| HR (1) | HRP20030288B1 (hu) |
| HU (1) | HUP0301351A3 (hu) |
| IL (1) | IL154809A0 (hu) |
| MX (1) | MXPA03003217A (hu) |
| NO (1) | NO20031687L (hu) |
| NZ (1) | NZ524232A (hu) |
| PL (1) | PL361675A1 (hu) |
| PT (1) | PT1326851E (hu) |
| SK (1) | SK4182003A3 (hu) |
| TR (1) | TR200402046T4 (hu) |
| WO (1) | WO2002032888A1 (hu) |
| ZA (1) | ZA200301720B (hu) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE338767T1 (de) * | 2002-04-09 | 2006-09-15 | Lilly Co Eli | Dipeptidische wachstumshormonsekretionsförderern |
| US7105526B2 (en) | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| AU2004274309B2 (en) | 2003-09-22 | 2010-04-08 | Msd K.K. | Novel piperidine derivative |
| EP1734963A4 (en) | 2004-04-02 | 2008-06-18 | Merck & Co Inc | METHOD FOR TREATING PEOPLE WITH METABOLIC AND ANTHROPOMETRIC DISORDER |
| EP1892241B1 (en) | 2005-05-30 | 2016-03-30 | Msd K.K. | Novel piperidine derivative |
| CA2618112A1 (en) | 2005-08-10 | 2007-02-15 | Banyu Pharmaceutical Co., Ltd. | Pyridone compound |
| CA2619770A1 (en) | 2005-08-24 | 2007-03-01 | Banyu Pharmaceutical Co., Ltd. | Phenylpyridone derivative |
| AU2006288153A1 (en) | 2005-09-07 | 2007-03-15 | Msd K.K. | Bicyclic aromatic substituted pyridone derivative |
| US8293900B2 (en) | 2005-09-29 | 2012-10-23 | Merck Sharp & Dohme Corp | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators |
| AU2006304836A1 (en) | 2005-10-21 | 2007-04-26 | Novartis Ag | Combination of a renin-inhibitor and an anti-dyslipidemic agent and/or an antiobesity agent |
| CA2627139A1 (en) | 2005-10-27 | 2007-05-03 | Banyu Pharmaceutical Co., Ltd. | Novel benzoxathiin derivative |
| JP4371164B2 (ja) | 2005-11-10 | 2009-11-25 | 萬有製薬株式会社 | アザ置換スピロ誘導体 |
| AU2007300627B2 (en) | 2006-09-22 | 2012-02-16 | Merck Sharp & Dohme Corp. | Method of treatment using fatty acid synthesis inhibitors |
| JPWO2008038692A1 (ja) | 2006-09-28 | 2010-01-28 | 萬有製薬株式会社 | ジアリールケチミン誘導体 |
| CA2682727C (en) | 2007-04-02 | 2016-03-22 | Banyu Pharmaceutical Co., Ltd. | Indoledione derivative |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| US20100120694A1 (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders |
| CA3089569C (en) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US20110015181A1 (en) | 2008-03-06 | 2011-01-20 | Makoto Ando | Alkylaminopyridine derivative |
| US20110015198A1 (en) | 2008-03-28 | 2011-01-20 | Banyu Pharmaceutical Co., Inc. | Diarylmethylamide derivative having melanin-concentrating hormone receptor antagonism |
| JPWO2009154132A1 (ja) | 2008-06-19 | 2011-12-01 | Ｍｓｄ株式会社 | スピロジアミン−ジアリールケトオキシム誘導体 |
| EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US20110124674A1 (en) | 2008-07-30 | 2011-05-26 | Hiroyuki Kishino | 5/5-or 5/6-membered condensed ring cycloalkylamine derivative |
| EP2348857B1 (en) | 2008-10-22 | 2016-02-24 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| JP5635991B2 (ja) | 2008-10-30 | 2014-12-03 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | イソニコチンアミドオレキシン受容体アンタゴニスト |
| CA2741672A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| US8314250B2 (en) * | 2009-11-24 | 2012-11-20 | Hoffmann-La Roche Inc. | Sultam derivatives |
| JP2013520502A (ja) | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| MX348131B (es) | 2011-02-25 | 2017-05-26 | Merck Sharp & Dohme | Novedosos derivados de azabencimidazol ciclico utiles como agentes antidiabeticos. |
| AR088352A1 (es) | 2011-10-19 | 2014-05-28 | Merck Sharp & Dohme | Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina |
| MX2015001500A (es) | 2012-08-02 | 2015-04-08 | Merck Sharp & Dohme | Compuestos antidiabeticos triciclicos. |
| AU2014219020A1 (en) | 2013-02-22 | 2015-07-23 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| US9650375B2 (en) | 2013-03-14 | 2017-05-16 | Merck Sharp & Dohme Corp. | Indole derivatives useful as anti-diabetic agents |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| RS65632B1 (sr) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Ltd | Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| CA2959208C (en) | 2014-08-29 | 2023-09-19 | Tes Pharma S.R.L. | Pyrimidine derivatives and their use as inhibitors of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase |
| TWI767945B (zh) | 2016-10-14 | 2022-06-21 | 義大利商Ｔｅｓ製藥（股份）責任有限公司 | α-胺基-β-羧基己二烯二酸半醛去羧酶之抑制劑 |
| EP3551176A4 (en) | 2016-12-06 | 2020-06-24 | Merck Sharp & Dohme Corp. | ANTIDIABETIC HETEROCYCLIC COMPOUNDS |
| US10968232B2 (en) | 2016-12-20 | 2021-04-06 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
| SG11202104550WA (en) | 2018-11-20 | 2021-05-28 | Tes Pharma S R L | INHIBITORS OF a-AMINO-ß-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE |
| TW202045476A (zh) | 2019-02-13 | 2020-12-16 | 美商默沙東藥廠 | 5-烷基吡咯啶食慾素受體促效劑 |
| US20230018413A1 (en) | 2019-08-08 | 2023-01-19 | Merck Sharp & Dohme Corp. | Heteroaryl pyrrolidine and piperidine orexin receptor agonists |
| CN116249697A (zh) | 2020-08-18 | 2023-06-09 | 默沙东有限责任公司 | 二环庚烷吡咯烷食欲素受体激动剂 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998018815A1 (en) * | 1996-10-25 | 1998-05-07 | Merck & Co., Inc. | Convergent process for the preparation of a growth hormone secretagogue |
| UA53716C2 (uk) * | 1997-06-25 | 2003-02-17 | Пфайзер Продактс Інк. | Тартратна сіль заміщеного дипептиду, спосіб її одержання, проміжні сполуки та спосіб їх одержання, фармацевтична композиція (варіанти), спосіб підвищення рівнів ендогенного гормону росту та спосіб лікування або профілактики захворювань (варіанти) |
-
2001
- 2001-10-09 BR BR0114630-0A patent/BR0114630A/pt not_active IP Right Cessation
- 2001-10-09 HU HU0301351A patent/HUP0301351A3/hu unknown
- 2001-10-09 EA EA200300462A patent/EA006102B1/ru not_active IP Right Cessation
- 2001-10-09 SK SK418-2003A patent/SK4182003A3/sk unknown
- 2001-10-09 TR TR2004/02046T patent/TR200402046T4/xx unknown
- 2001-10-09 NZ NZ524232A patent/NZ524232A/en unknown
- 2001-10-09 CZ CZ20031029A patent/CZ20031029A3/cs unknown
- 2001-10-09 CA CA002419388A patent/CA2419388A1/en not_active Abandoned
- 2001-10-09 WO PCT/US2001/027756 patent/WO2002032888A1/en active IP Right Grant
- 2001-10-09 EP EP01979233A patent/EP1326851B1/en not_active Expired - Lifetime
- 2001-10-09 AT AT01979233T patent/ATE270280T1/de not_active IP Right Cessation
- 2001-10-09 JP JP2002536270A patent/JP2004511552A/ja active Pending
- 2001-10-09 AU AU1121902A patent/AU1121902A/xx active Pending
- 2001-10-09 DZ DZ013482A patent/DZ3482A1/fr active
- 2001-10-09 KR KR10-2003-7005203A patent/KR20030042014A/ko not_active Application Discontinuation
- 2001-10-09 DE DE60104141T patent/DE60104141T2/de not_active Expired - Lifetime
- 2001-10-09 PT PT01979233T patent/PT1326851E/pt unknown
- 2001-10-09 ES ES01979233T patent/ES2223926T3/es not_active Expired - Lifetime
- 2001-10-09 CN CNA018172822A patent/CN1469871A/zh active Pending
- 2001-10-09 PL PL01361675A patent/PL361675A1/xx not_active Application Discontinuation
- 2001-10-09 MX MXPA03003217A patent/MXPA03003217A/es unknown
- 2001-10-09 IL IL15480901A patent/IL154809A0/xx unknown
- 2001-10-09 AU AU2002211219A patent/AU2002211219B2/en not_active Ceased
-
2003
- 2003-02-28 ZA ZA200301720A patent/ZA200301720B/en unknown
- 2003-04-10 EC EC2003004551A patent/ECSP034551A/es unknown
- 2003-04-11 NO NO20031687A patent/NO20031687L/no unknown
- 2003-04-14 HR HR20030288A patent/HRP20030288B1/xx not_active IP Right Cessation
- 2003-12-31 HK HK03109504A patent/HK1058194A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EA006102B1 (ru) | 2005-08-25 |
| HK1058194A1 (en) | 2004-05-07 |
| DE60104141D1 (de) | 2004-08-05 |
| CA2419388A1 (en) | 2002-04-25 |
| HRP20030288B1 (en) | 2005-02-28 |
| PT1326851E (pt) | 2004-11-30 |
| JP2004511552A (ja) | 2004-04-15 |
| EP1326851B1 (en) | 2004-06-30 |
| SK4182003A3 (en) | 2004-01-08 |
| TR200402046T4 (tr) | 2004-10-21 |
| EA200300462A1 (ru) | 2003-08-28 |
| DE60104141T2 (de) | 2005-06-30 |
| NO20031687L (no) | 2003-05-08 |
| PL361675A1 (en) | 2004-10-04 |
| KR20030042014A (ko) | 2003-05-27 |
| EP1326851A1 (en) | 2003-07-16 |
| CN1469871A (zh) | 2004-01-21 |
| NO20031687D0 (no) | 2003-04-11 |
| IL154809A0 (en) | 2003-10-31 |
| MXPA03003217A (es) | 2003-06-06 |
| AU2002211219B2 (en) | 2006-09-14 |
| CZ20031029A3 (cs) | 2003-09-17 |
| ECSP034551A (es) | 2003-05-26 |
| AU1121902A (en) | 2002-04-29 |
| DZ3482A1 (fr) | 2002-04-25 |
| WO2002032888A1 (en) | 2002-04-25 |
| ES2223926T3 (es) | 2005-03-01 |
| BR0114630A (pt) | 2003-07-01 |
| ATE270280T1 (de) | 2004-07-15 |
| ZA200301720B (en) | 2004-06-21 |
| HRP20030288A2 (en) | 2004-02-29 |
| HUP0301351A2 (hu) | 2003-11-28 |
| NZ524232A (en) | 2005-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0301351A3 (en) | Use of substituted dipeptides as growth hormone secretagogues, process for their preparation and pharmaceutical compositions containing them | |
| HK1058199A1 (en) | Novel sg(y) crystalline form of perindopril tert-butylamine salt, preparation method, and pharmaceutical compositions containing same | |
| HUP0302519A3 (en) | Crystalline forms of atorvastatin, process for their preparation and pharmaceutical compositions containing them | |
| HUP0400927A3 (en) | New crystalline form and pure modafinil, process of preparing them, and pharmaceutical compositions containing the new crystalline form | |
| HU0102813D0 (en) | New betha crystalline form of perindopril tert-butylamine salt, process for its preparation and pharmaceutical compositions containing it | |
| HUP0301069A3 (en) | Novel biarylcarboxamides, process for their preparation, pharmaceutical compositions containing them and their use | |
| HUP0103494A2 (en) | Process for intermittent administration use of growth hormone secretagogues for the manufacture of pharmaceutical compositions for intermittent administration and kit comprising thereof | |
| HUP0303078A3 (en) | Cyclic peptidies process for their preparation pharmaceutical compositions containing them and their use | |
| HUP0100950A3 (en) | Cyclic amino compounds, use of them for producing pharmaceutical compositions and pharmaceutical compositions containing them | |
| HUP0204245A3 (en) | Novel n-azabicyclo-amide derivatives, process for their preparation, pharmaceutical compositions containing them and their use | |
| AU2001276419A1 (en) | Novel beta crystalline form of perindopril tert- butylamine salt, preparation method and pharmaceutical compositions containing same | |
| HUP0301688A3 (en) | Amino alcohol derivatives, process for their preparation and pharmaceutical compositions containing them | |
| HUP0204226A3 (en) | Quinazoline derivatives, pharmaceutical compositions containing them, their use and process for the preparation of the compounds | |
| AU2001276420A1 (en) | Novel gamma crystalline form of perindopril tert-butylamine salt, preparation method, and pharmaceutical compositions containing same. | |
| HUP0105108A3 (en) | Amide compounds, process for their preparation and pharmaceutical compositions containing them | |
| HUP0003053A3 (en) | Crystalline forms of 33-epichloro-33-desoxyascomycin, process for their preparation and pharmaceutical compositions containing them | |
| HUP0202233A3 (en) | Derivatives and analogues of galanthamin, their use, pharmaceutical compositions containing them and process for the preparation of them | |
| HUP0300389A3 (en) | Crystalline form ii of cabergoline, process for its preparation and pharmaceutical compositions containing it | |
| HUP0302912A3 (en) | Betha-thio-amino acids, process for their preparation and pharmaceutical compositions containing them | |
| HUP0203032A3 (en) | Eplerenone crystalline form exhibiting enhanced dissolution rate, process for their preparation and pharmaceutical compositions containing them and their use | |
| HUP0303045A3 (en) | Pyrimidine derivatives, process for their preparation, pharmaceutical compositions containing them and their use | |
| HUP0303105A3 (en) | Novel aminocyclohexane derivatives, process for their preparation, pharmaceutical compositions containing them and their use | |
| HUP0202988A3 (en) | Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-one derivatives and their use as lipase inhibitors, process for their preparation and pharmaceutical compositions containing them | |
| HUP0204005A3 (en) | Novel forms of pravastatin sodium, process for their preparation and pharmaceutical compositions containing them | |
| HUP0204001A3 (en) | Substituted aminomethyl-phenyl-cyclohexane derivatives, process for their preparation and pharmaceutical compositions containing them |