HUP0203559A2 - A szertralin hidroklorid polimorf formái, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents

A szertralin hidroklorid polimorf formái, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0203559A2
HUP0203559A2 HU0203559A HUP0203559A HUP0203559A2 HU P0203559 A2 HUP0203559 A2 HU P0203559A2 HU 0203559 A HU0203559 A HU 0203559A HU P0203559 A HUP0203559 A HU P0203559A HU P0203559 A2 HUP0203559 A2 HU P0203559A2
Authority
HU
Hungary
Prior art keywords
sertraline hydrochloride
preparation
pharmaceutical compositions
compositions containing
polymorphic forms
Prior art date
Application number
HU0203559A
Other languages
English (en)
Inventor
Andreas Burkhard
Hans-Jörg Kirner
Claudia Marcolli
Regine Peter
Paul Adriaan Schaaf
Franz Schwarzenbach
Martin Szelagiewicz
Original Assignee
Ciba Specialty Chemicals Holding Inc.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8243113&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0203559(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Specialty Chemicals Holding Inc., filed Critical Ciba Specialty Chemicals Holding Inc.,
Publication of HUP0203559A2 publication Critical patent/HUP0203559A2/hu
Publication of HUP0203559A3 publication Critical patent/HUP0203559A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgya az (1) képletű szertralin hidroklorid CSC2 polimorfformának nevezett olyan kioldódási tulajdonságokkal rendelkezőkristályformája, amely meglepő módon fokozza egy gyógyszerfelszívódásának mértékét. A találmány tárgyát képezik továbbá aszertralin hidroklorid szolvátok különböző kristályformái, a CSC1polimorf formának nevezett szertralin hidroklorid hidrátokkristályformái, eljárás a szerfiralin hidroklorid amorf formájánakelőállítására, és különböző eljárások a polimorf (I), (II), (V) és T1formák előállítására. Ó
HU0203559A 1999-10-29 2000-10-23 Polymorphic forms of sertraline hydrochloride, process for their preparation and pharmaceutical compositions containing them HUP0203559A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99810981 1999-10-29
PCT/EP2000/010416 WO2001032601A1 (en) 1999-10-29 2000-10-23 Polymorphic forms of sertraline hydrochloride

Publications (2)

Publication Number Publication Date
HUP0203559A2 true HUP0203559A2 (hu) 2003-03-28
HUP0203559A3 HUP0203559A3 (en) 2008-01-28

Family

ID=8243113

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203559A HUP0203559A3 (en) 1999-10-29 2000-10-23 Polymorphic forms of sertraline hydrochloride, process for their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (2) US6872853B1 (hu)
EP (1) EP1224160B1 (hu)
JP (1) JP2003513062A (hu)
CN (1) CN1384816A (hu)
AR (1) AR026293A1 (hu)
AT (1) ATE409684T1 (hu)
AU (1) AU1386301A (hu)
CA (1) CA2387135A1 (hu)
DE (1) DE60040406D1 (hu)
HU (1) HUP0203559A3 (hu)
IL (2) IL149050A0 (hu)
MX (1) MXPA02004255A (hu)
MY (1) MY141509A (hu)
TR (1) TR200201146T2 (hu)
TW (1) TWI260315B (hu)
WO (1) WO2001032601A1 (hu)
ZA (1) ZA200203254B (hu)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6500987B1 (en) * 1998-11-27 2002-12-31 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride polymorphs
ES2255320T3 (es) * 1998-11-27 2006-06-16 Teva Pharmaceutical Industries Ltd. Forma v clorhidrato de sertralina.
EP1634865A1 (en) * 1998-11-27 2006-03-15 Teva Pharmaceutical Industries Ltd Sertraline hydrochloride polymorphs
US6495721B1 (en) 1999-08-09 2002-12-17 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride Form II and methods for the preparation thereof
US20050119351A1 (en) * 1999-10-29 2005-06-02 Van Der Schaaf Paul A. Polymorphic forms of sertraline hydrochloride
US7442838B2 (en) * 1999-10-29 2008-10-28 Ciba Specialty Chemicals Corp. Polymorphic forms of sertraline hydrochloride
EP1774965A3 (en) * 1999-12-21 2007-10-10 Teva Pharmaceutical Industries Ltd Novel sertraline hydrochloride polymorph, processes for preparing them, compositions containing them and methods of using them
EP1248605B1 (en) 1999-12-21 2007-02-21 Teva Pharmaceutical Industries Ltd. Novel sertraline hydrochloride polymorphs, processes for preparing them, compositions containing them and methods of using them
IN192343B (hu) * 2000-05-26 2004-04-10 Ranbaxy Lab Ltd
US7067700B2 (en) 2001-05-31 2006-06-27 Fermion Oy Process for preparing sertraline hydrochloride polymorphic form II
US6897340B2 (en) 2002-04-29 2005-05-24 Teva Pharmaceutical Industries Ltd. Processes for preparation of polymorphic form II of sertraline hydrochloride
EP1527617A4 (en) * 2002-06-27 2006-01-04 Interdigital Tech Corp PAIR EXCHANGE TO PAIR USER EQUIPMENT MEASUREMENT INFORMATION BETWEEN RADIO NETWORK CONTROLLERS
JP2007502329A (ja) * 2003-05-23 2007-02-08 トランスフォーム・ファーマシューティカルズ・インコーポレイテッド セルトラリン組成物
DE602004027401D1 (de) 2003-11-04 2010-07-08 Cipla Ltd Verfahren zur herstellung von polymorphen von sertralin hydrochlorid
US20070173536A1 (en) * 2004-02-06 2007-07-26 Ciba Specialty Chemicals Holding Inc. Crystalline forms of zolmitriptan
WO2007008317A2 (en) * 2005-06-09 2007-01-18 Teva Pharmaceutical Industries Ltd. Process for preparation of sertraline hydrochloride form i
US7518019B2 (en) 2006-06-01 2009-04-14 Hetero Drugs Limited Processes for preparing sertraline hydrochloride crystalline forms
CA2594198A1 (en) * 2007-07-20 2009-01-20 Apotex Pharmachem Inc. A novel process for the preparation of sertraline hydrochloride form ii
US9993793B2 (en) 2010-04-28 2018-06-12 The Procter & Gamble Company Delivery particles
US9186642B2 (en) 2010-04-28 2015-11-17 The Procter & Gamble Company Delivery particle
MX2013010980A (es) 2011-04-07 2013-10-30 Procter & Gamble Composiciones de limpieza personal con deposito mejorado de microcapsulas de poliacrilato.
WO2012138690A2 (en) 2011-04-07 2012-10-11 The Procter & Gamble Company Conditioner compositions with increased deposition of polyacrylate microcapsules
CN103458858B (zh) 2011-04-07 2016-04-27 宝洁公司 具有增强的聚丙烯酸酯微胶囊的沉积的洗发剂组合物
CN105061217A (zh) * 2015-06-30 2015-11-18 徐静 枸橼酸舍曲林的2种晶型及其制备方法
CN112552188B (zh) * 2020-12-17 2023-07-28 山西仟源医药集团股份有限公司 盐酸舍曲林晶型i的制备方法
CN113588626B (zh) * 2021-08-24 2024-05-24 上海师范大学 一种苯丙氨酸对映体的拉曼光谱检测方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US5082970A (en) 1991-03-06 1992-01-21 Pfizer Inc. Process for recycling amine isomer
GB9114947D0 (en) 1991-07-11 1991-08-28 Pfizer Ltd Process for preparing sertraline
US5248699A (en) * 1992-08-13 1993-09-28 Pfizer Inc. Sertraline polymorph
US5734083A (en) * 1996-05-17 1998-03-31 Torcan Chemical Ltd. Sertraline polymorph
HU222341B1 (hu) 1996-12-18 2003-06-28 Richter Gedeon Vegyészeti Gyár Rt. Eljárás sertralin előállítására és az eljárásban alkalmazott intermedier
DE69713353D1 (de) * 1997-12-11 2002-07-18 Torcan Chemical Ltd Sertralin-Polymorph mit verbesserter Wasserlöslichkeit
ES2217748T3 (es) 1998-03-18 2004-11-01 Ciba Specialty Chemicals Holding Inc. Procedimiento para la hidrogenacin catalitica cis-selectiva de ciclohexilidenaminas.
JP2000026378A (ja) 1998-07-03 2000-01-25 Sumika Fine Chemicals Co Ltd 塩酸セルトラリンの製法
ES2255320T3 (es) * 1998-11-27 2006-06-16 Teva Pharmaceutical Industries Ltd. Forma v clorhidrato de sertralina.
US6500987B1 (en) 1998-11-27 2002-12-31 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride polymorphs
US6495721B1 (en) 1999-08-09 2002-12-17 Teva Pharmaceutical Industries Ltd. Sertraline hydrochloride Form II and methods for the preparation thereof
EP1248605B1 (en) 1999-12-21 2007-02-21 Teva Pharmaceutical Industries Ltd. Novel sertraline hydrochloride polymorphs, processes for preparing them, compositions containing them and methods of using them

Also Published As

Publication number Publication date
CN1384816A (zh) 2002-12-11
TR200201146T2 (tr) 2004-12-21
EP1224160A1 (en) 2002-07-24
AU1386301A (en) 2001-05-14
ATE409684T1 (de) 2008-10-15
MY141509A (en) 2010-05-14
US6939992B2 (en) 2005-09-06
TWI260315B (en) 2006-08-21
IL149050A (en) 2007-03-08
MXPA02004255A (es) 2002-10-17
IL149050A0 (en) 2002-11-10
WO2001032601A1 (en) 2001-05-10
CA2387135A1 (en) 2001-05-10
EP1224160B1 (en) 2008-10-01
JP2003513062A (ja) 2003-04-08
US6872853B1 (en) 2005-03-29
AR026293A1 (es) 2003-02-05
HUP0203559A3 (en) 2008-01-28
US20040132828A1 (en) 2004-07-08
ZA200203254B (en) 2003-07-22
DE60040406D1 (de) 2008-11-13

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