HUP0400343A2 - Ciklopropil-indol-származékok mint szelektív szerotonin-újrafelvétel inhibitorok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents
Ciklopropil-indol-származékok mint szelektív szerotonin-újrafelvétel inhibitorok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP0400343A2 HUP0400343A2 HU0400343A HUP0400343A HUP0400343A2 HU P0400343 A2 HUP0400343 A2 HU P0400343A2 HU 0400343 A HU0400343 A HU 0400343A HU P0400343 A HUP0400343 A HU P0400343A HU P0400343 A2 HUP0400343 A2 HU P0400343A2
- Authority
- HU
- Hungary
- Prior art keywords
- cyclopropylindole
- derivatives
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- INCAQIRDTKGRNM-UHFFFAOYSA-N 2-cyclopropyl-1h-indole Chemical class C1CC1C1=CC2=CC=CC=C2N1 INCAQIRDTKGRNM-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 title 1
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 208000030814 Eating disease Diseases 0.000 abstract 1
- 208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 235000014632 disordered eating Nutrition 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 206010025482 malaise Diseases 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 206010036596 premature ejaculation Diseases 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
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- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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Abstract
A találmány tárgyát általános képletű vegyületek - ahol, különbözőmegkötésekkel A1, A2 és A4 kötés vagy alkilén-típusú csoport; A3alkilén- vagy alkilidén-típusú csoport; X, X1, X2 és X3 egymástólfüggetlenül =C= vagy =CH-; J alkilcsoport; p=0 vagy 1, G jelentése N,O vagy S-atom; G1 jelentése N vagy =CH-; Rl, R2, R3, R4 és R5hidrogénatom, alkil-, aromás, cikloalkil-, heterociklikus csoport vagyegyéb összetett szubsztituens; n=0 vagy 1, m=0 vagy 1 - ésgyógyszerészetileg elfogadható sóik vagy szolvátjaik, és ezekettartalmazó, különböző pszichiátriai betegségek, például depresszió,szorongás, táplálkozási zavarok, korai magömlés, krónikus fájdalom,premenstruációs rosszullét, rögeszmés/kényszerképzetes állapotokkezelésére alkalmazható gyógyszerkészítmények képezik. Ó
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27988801P | 2001-03-29 | 2001-03-29 | |
US29312201P | 2001-05-23 | 2001-05-23 | |
US32780401P | 2001-10-09 | 2001-10-09 | |
PCT/US2002/006627 WO2002079152A1 (en) | 2001-03-29 | 2002-03-05 | Cyclopropylindole derivatives as selective serotonin reuptake inhibitors |
Publications (1)
Publication Number | Publication Date |
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HUP0400343A2 true HUP0400343A2 (hu) | 2004-09-28 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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HU0400343A HUP0400343A2 (hu) | 2001-03-29 | 2002-03-05 | Ciklopropil-indol-származékok mint szelektív szerotonin-újrafelvétel inhibitorok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
Country Status (17)
Country | Link |
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US (2) | US6777437B2 (hu) |
EP (1) | EP1373203A1 (hu) |
JP (1) | JP2004531506A (hu) |
AR (1) | AR035793A1 (hu) |
BG (1) | BG108207A (hu) |
CA (1) | CA2442525A1 (hu) |
CZ (1) | CZ20032644A3 (hu) |
EE (1) | EE200300478A (hu) |
HU (1) | HUP0400343A2 (hu) |
IL (1) | IL158044A0 (hu) |
IS (1) | IS6969A (hu) |
MX (1) | MXPA03008807A (hu) |
NO (1) | NO20034307L (hu) |
PE (1) | PE20020975A1 (hu) |
PL (1) | PL364580A1 (hu) |
SK (1) | SK12012003A3 (hu) |
WO (1) | WO2002079152A1 (hu) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200418838A (en) | 2002-09-18 | 2004-10-01 | Bristol Myers Squibb Co | Compounds for the treatment of premature ejaculation |
AU2003270669A1 (en) | 2002-09-18 | 2004-04-08 | Bristol-Myers Squibb Company | Cyclopentyl indole derivatives |
CA2524682A1 (en) * | 2003-05-09 | 2004-11-18 | Laboratorios Del Dr. Esteve S.A. | Use of sulphonamide derivatives for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion |
DE10337184A1 (de) * | 2003-08-13 | 2005-03-10 | Gruenenthal Gmbh | Substituierte 3-Pyrrolidin-Indol-Derivate |
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- 2002-03-05 HU HU0400343A patent/HUP0400343A2/hu unknown
- 2002-03-05 EE EEP200300478A patent/EE200300478A/xx unknown
- 2002-03-05 SK SK12012003A patent/SK12012003A3/sk unknown
- 2002-03-05 IL IL15804402A patent/IL158044A0/xx unknown
- 2002-03-05 CA CA002442525A patent/CA2442525A1/en not_active Abandoned
- 2002-03-05 US US10/091,232 patent/US6777437B2/en not_active Expired - Lifetime
- 2002-03-05 WO PCT/US2002/006627 patent/WO2002079152A1/en not_active Application Discontinuation
- 2002-03-05 CZ CZ20032644A patent/CZ20032644A3/cs unknown
- 2002-03-05 JP JP2002577779A patent/JP2004531506A/ja active Pending
- 2002-03-05 EP EP02709778A patent/EP1373203A1/en not_active Withdrawn
- 2002-03-05 MX MXPA03008807A patent/MXPA03008807A/es unknown
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CZ20032644A3 (en) | 2004-06-16 |
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PL364580A1 (en) | 2004-12-13 |
US6777437B2 (en) | 2004-08-17 |
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US6822100B2 (en) | 2004-11-23 |
IL158044A0 (en) | 2004-03-28 |
MXPA03008807A (es) | 2004-02-12 |
EE200300478A (et) | 2003-12-15 |
US20030073849A1 (en) | 2003-04-17 |
SK12012003A3 (en) | 2004-10-05 |
IS6969A (is) | 2003-09-26 |
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