PT1068184E - Derivados n-ariloxietilamina para o tratamento de depressao - Google Patents

Derivados n-ariloxietilamina para o tratamento de depressao

Info

Publication number
PT1068184E
PT1068184E PT99915318T PT99915318T PT1068184E PT 1068184 E PT1068184 E PT 1068184E PT 99915318 T PT99915318 T PT 99915318T PT 99915318 T PT99915318 T PT 99915318T PT 1068184 E PT1068184 E PT 1068184E
Authority
PT
Portugal
Prior art keywords
hydrogen
halogen
lower alkyl
alkoxy
alkyl
Prior art date
Application number
PT99915318T
Other languages
English (en)
Inventor
Richard Eric Mewshaw
Dahui Zhou
Ping Zhou
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PT1068184E publication Critical patent/PT1068184E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT99915318T 1998-04-08 1999-04-07 Derivados n-ariloxietilamina para o tratamento de depressao PT1068184E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5730798A 1998-04-08 1998-04-08

Publications (1)

Publication Number Publication Date
PT1068184E true PT1068184E (pt) 2002-12-31

Family

ID=22009801

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99915318T PT1068184E (pt) 1998-04-08 1999-04-07 Derivados n-ariloxietilamina para o tratamento de depressao

Country Status (11)

Country Link
EP (1) EP1068184B1 (pt)
JP (1) JP2002510676A (pt)
CN (1) CN1160332C (pt)
AT (1) ATE223379T1 (pt)
AU (1) AU3386299A (pt)
CA (1) CA2327303A1 (pt)
DE (1) DE69902766T2 (pt)
DK (1) DK1068184T3 (pt)
ES (1) ES2182509T3 (pt)
PT (1) PT1068184E (pt)
WO (1) WO1999051576A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA02004555A (es) * 1999-11-08 2004-09-10 Wyeth Corp Azetidinas de [(indol-??3-il)cicloalquil]-3-substituidas para el tratamiento de padecimientos del sistema nervioso central.
DE10006139A1 (de) * 2000-02-11 2001-08-16 Merck Patent Gmbh Indol-3-yl-Derivate
HUP0400343A2 (hu) 2001-03-29 2004-09-28 Bristol-Myers Squibb Co. Ciklopropil-indol-származékok mint szelektív szerotonin-újrafelvétel inhibitorok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
US7041697B2 (en) * 2002-09-12 2006-05-09 Wyeth Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan
DE10305739A1 (de) * 2003-02-11 2004-08-19 Merck Patent Gmbh Benzofuranderivate
DE10306941A1 (de) 2003-02-18 2004-08-26 Merck Patent Gmbh Benzofuranoxyethylamine
DE102006033109A1 (de) 2006-07-18 2008-01-31 Grünenthal GmbH Substituierte Heteroaryl-Derivate
WO2009128088A2 (en) * 2008-04-15 2009-10-22 Shodhana Laboratories Limited Preparation of 2-(2-alkoxy phenoxy) ethylamine, an intermediate of carvedilol and tamsulosin
CN112358450A (zh) * 2020-11-19 2021-02-12 南京艾康生物科技有限公司 一种4-(苄氧基)-2-甲基-1H-苯并[d]咪唑-6-羧酸的合成方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468882A (en) * 1966-10-07 1969-09-23 Sterling Drug Inc Phenylhydrazone derivatives as intermediates for preparing indoles
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
DE2827874A1 (de) * 1978-06-24 1980-02-07 Merck Patent Gmbh Indolalkylamine und verfahren zu ihrer herstellung
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
US5124332A (en) * 1991-01-28 1992-06-23 Warner-Lambert Company Substituted indoles as central nervous system agents
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
JPH05125024A (ja) * 1991-11-05 1993-05-21 Yamanouchi Pharmaceut Co Ltd 新規なアリールオキシアルキルアミン誘導体又はその塩
US5314896A (en) * 1991-11-20 1994-05-24 Warner-Lambert Company 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents
JPH05255302A (ja) * 1992-03-09 1993-10-05 Yamanouchi Pharmaceut Co Ltd 新規なクロマニルオキシアルキルアミン誘導体
IT1271352B (it) * 1993-04-08 1997-05-27 Boehringer Ingelheim Italia Derivati dell'indolo utili nel trattamento dei disturbi del sistema nervoso centrale
US5436264A (en) * 1993-08-19 1995-07-25 Syntex (U.S.A.) Inc. N-aryloxyalkyl tryptamine α1 -adrenergic receptor antagonists
US5468767A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antidepressant 3-(aminocycloalkenyl)-indole-5-nitrile derivatives
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
JPH0940648A (ja) * 1995-08-02 1997-02-10 Yamanouchi Pharmaceut Co Ltd 新規な8−(2−アミノアルコキシ)キノリン誘導体
CN1234024A (zh) * 1996-08-27 1999-11-03 美国家用产品公司 4-氨基乙氧基吲哚衍生物
PT923548E (pt) * 1996-08-27 2003-06-30 Wyeth Corp 4-aminoetoxi-indolos como agonistas d2 da dopaminae como ligandos da 5ht1a

Also Published As

Publication number Publication date
ES2182509T3 (es) 2003-03-01
CN1303373A (zh) 2001-07-11
WO1999051576A1 (en) 1999-10-14
AU3386299A (en) 1999-10-25
DE69902766T2 (de) 2003-02-06
EP1068184B1 (en) 2002-09-04
ATE223379T1 (de) 2002-09-15
CA2327303A1 (en) 1999-10-14
DE69902766D1 (de) 2002-10-10
JP2002510676A (ja) 2002-04-09
CN1160332C (zh) 2004-08-04
EP1068184A1 (en) 2001-01-17
DK1068184T3 (da) 2002-12-30

Similar Documents

Publication Publication Date Title
BR9609950A (pt) Uso de derivados de adamantano para o tratamento de doenças do ouvido interno
ATE283268T1 (de) 2-adamantylethylamine und deren verwendung bei der behandlung von abnormalitäten in der glutamat transmission
HUP9904361A2 (hu) Izobutil-gaba és származékai alkalmazása fájdalom kezelésére
MY117896A (en) Quinazoline derivatives
ES530902A0 (es) Procedimiento para preparar derivados de piperazina
PT1068184E (pt) Derivados n-ariloxietilamina para o tratamento de depressao
FI923540A (fi) Arylalkylaminer och -amider med antikonvulsiva och nervskyddande egenskaper.
DE69824476D1 (de) Alkylene-Derivat, Anti-ulcus und antibakterielle Arzneimittel
SE9702716D0 (sv) Substituted phenylazacycloalkanes in the treatment of cognitive disorders
TR200001926T2 (tr) Vasküler başağrılarına karşı lokal anesteziklerin yeni kullanımı
PT1049672E (pt) Derivados de azetidinocarboxamida para o tratamento de disturbios do snc
CO5040091A1 (es) Derivados de urea
BR9808234A (pt) Uso de 2,3,4,5-tetrahidro-1h-3-benzazepinas para a produção de uma composição farmacêutica para o tratamento de distúrbios do sono
ES2102019T3 (es) 2,3,4,5-tetrahidro-1h-3-benzazepinas y sus sales de adicion farmaceuticamente aceptables.
DE69619088T2 (de) Quinoxalin-Derivate zur Behandlung von Tinnitus
AP2000002009A0 (en) Tetrahydronaphthyridinyl-carboxamides having anti-convulsant activity.
PT1049670E (pt) Derivados de azetidinocarboxamida para o tratamento de perturbacoes do snc
PT1068199E (pt) N-ariloxietil-indoli-alquilaminas para o tratamento da depressao
PT1140919E (pt) Novos derivados de ciclohexano 1,4-dissubstituido para o tratamento da depressao
ATE200673T1 (de) 1,9-diazabicyclo(4.3.0)nona-3,8-dienderivate