DK1068184T3 - N-aryloxyethylaminderivater til behandling af despression - Google Patents
N-aryloxyethylaminderivater til behandling af despressionInfo
- Publication number
- DK1068184T3 DK1068184T3 DK99915318T DK99915318T DK1068184T3 DK 1068184 T3 DK1068184 T3 DK 1068184T3 DK 99915318 T DK99915318 T DK 99915318T DK 99915318 T DK99915318 T DK 99915318T DK 1068184 T3 DK1068184 T3 DK 1068184T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen
- halogen
- lower alkyl
- depression
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5730798A | 1998-04-08 | 1998-04-08 | |
| PCT/US1999/007622 WO1999051576A1 (en) | 1998-04-08 | 1999-04-07 | N-aryloxyethylamine derivatives for the treatment of depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1068184T3 true DK1068184T3 (da) | 2002-12-30 |
Family
ID=22009801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99915318T DK1068184T3 (da) | 1998-04-08 | 1999-04-07 | N-aryloxyethylaminderivater til behandling af despression |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1068184B1 (da) |
| JP (1) | JP2002510676A (da) |
| CN (1) | CN1160332C (da) |
| AT (1) | ATE223379T1 (da) |
| AU (1) | AU3386299A (da) |
| CA (1) | CA2327303A1 (da) |
| DE (1) | DE69902766T2 (da) |
| DK (1) | DK1068184T3 (da) |
| ES (1) | ES2182509T3 (da) |
| PT (1) | PT1068184E (da) |
| WO (1) | WO1999051576A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0015401A (pt) * | 1999-11-08 | 2002-07-02 | Wyeth Corp | [(indol-3-il)-cicloalquil]-3-azetidinas substituìdas para o tratamento de distúrbios do sistema nervoso central |
| DE10006139A1 (de) * | 2000-02-11 | 2001-08-16 | Merck Patent Gmbh | Indol-3-yl-Derivate |
| HUP0400343A2 (hu) | 2001-03-29 | 2004-09-28 | Bristol-Myers Squibb Co. | Ciklopropil-indol-származékok mint szelektív szerotonin-újrafelvétel inhibitorok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
| US7041697B2 (en) * | 2002-09-12 | 2006-05-09 | Wyeth | Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan |
| DE10305739A1 (de) * | 2003-02-11 | 2004-08-19 | Merck Patent Gmbh | Benzofuranderivate |
| DE10306941A1 (de) | 2003-02-18 | 2004-08-26 | Merck Patent Gmbh | Benzofuranoxyethylamine |
| DE102006033109A1 (de) * | 2006-07-18 | 2008-01-31 | Grünenthal GmbH | Substituierte Heteroaryl-Derivate |
| WO2009128088A2 (en) * | 2008-04-15 | 2009-10-22 | Shodhana Laboratories Limited | Preparation of 2-(2-alkoxy phenoxy) ethylamine, an intermediate of carvedilol and tamsulosin |
| CN112358450A (zh) * | 2020-11-19 | 2021-02-12 | 南京艾康生物科技有限公司 | 一种4-(苄氧基)-2-甲基-1H-苯并[d]咪唑-6-羧酸的合成方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3468882A (en) * | 1966-10-07 | 1969-09-23 | Sterling Drug Inc | Phenylhydrazone derivatives as intermediates for preparing indoles |
| US3371098A (en) * | 1966-11-29 | 1968-02-27 | Philips Corp | 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles |
| DE2827874A1 (de) * | 1978-06-24 | 1980-02-07 | Merck Patent Gmbh | Indolalkylamine und verfahren zu ihrer herstellung |
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| US5124332A (en) * | 1991-01-28 | 1992-06-23 | Warner-Lambert Company | Substituted indoles as central nervous system agents |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| JPH05125024A (ja) * | 1991-11-05 | 1993-05-21 | Yamanouchi Pharmaceut Co Ltd | 新規なアリールオキシアルキルアミン誘導体又はその塩 |
| US5314896A (en) * | 1991-11-20 | 1994-05-24 | Warner-Lambert Company | 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents |
| JPH05255302A (ja) * | 1992-03-09 | 1993-10-05 | Yamanouchi Pharmaceut Co Ltd | 新規なクロマニルオキシアルキルアミン誘導体 |
| IT1271352B (it) * | 1993-04-08 | 1997-05-27 | Boehringer Ingelheim Italia | Derivati dell'indolo utili nel trattamento dei disturbi del sistema nervoso centrale |
| US5436264A (en) * | 1993-08-19 | 1995-07-25 | Syntex (U.S.A.) Inc. | N-aryloxyalkyl tryptamine α1 -adrenergic receptor antagonists |
| US5468767A (en) * | 1994-01-06 | 1995-11-21 | Bristol-Myers Squibb Company | Antidepressant 3-(aminocycloalkenyl)-indole-5-nitrile derivatives |
| US5576321A (en) * | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
| JPH0940648A (ja) * | 1995-08-02 | 1997-02-10 | Yamanouchi Pharmaceut Co Ltd | 新規な８−（２−アミノアルコキシ）キノリン誘導体 |
| ES2179362T3 (es) * | 1996-08-27 | 2003-01-16 | Wyeth Corp | Derivados de 4-aminoetoxi indolona. |
| PT923548E (pt) * | 1996-08-27 | 2003-06-30 | Wyeth Corp | 4-aminoetoxi-indolos como agonistas d2 da dopaminae como ligandos da 5ht1a |
-
1999
- 1999-04-07 PT PT99915318T patent/PT1068184E/pt unknown
- 1999-04-07 DE DE69902766T patent/DE69902766T2/de not_active Expired - Fee Related
- 1999-04-07 AU AU33862/99A patent/AU3386299A/en not_active Abandoned
- 1999-04-07 CA CA002327303A patent/CA2327303A1/en not_active Abandoned
- 1999-04-07 DK DK99915318T patent/DK1068184T3/da active
- 1999-04-07 EP EP99915318A patent/EP1068184B1/en not_active Expired - Lifetime
- 1999-04-07 AT AT99915318T patent/ATE223379T1/de not_active IP Right Cessation
- 1999-04-07 CN CNB998068934A patent/CN1160332C/zh not_active Expired - Fee Related
- 1999-04-07 ES ES99915318T patent/ES2182509T3/es not_active Expired - Lifetime
- 1999-04-07 WO PCT/US1999/007622 patent/WO1999051576A1/en active IP Right Grant
- 1999-04-07 JP JP2000542297A patent/JP2002510676A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1303373A (zh) | 2001-07-11 |
| ES2182509T3 (es) | 2003-03-01 |
| PT1068184E (pt) | 2002-12-31 |
| WO1999051576A1 (en) | 1999-10-14 |
| ATE223379T1 (de) | 2002-09-15 |
| CA2327303A1 (en) | 1999-10-14 |
| DE69902766T2 (de) | 2003-02-06 |
| EP1068184B1 (en) | 2002-09-04 |
| AU3386299A (en) | 1999-10-25 |
| CN1160332C (zh) | 2004-08-04 |
| DE69902766D1 (de) | 2002-10-10 |
| EP1068184A1 (en) | 2001-01-17 |
| JP2002510676A (ja) | 2002-04-09 |
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