DK1049670T3 - Azetidincarboxamidderivater til behandling af CNS-lidelser - Google Patents

Azetidincarboxamidderivater til behandling af CNS-lidelser

Info

Publication number
DK1049670T3
DK1049670T3 DK99901781T DK99901781T DK1049670T3 DK 1049670 T3 DK1049670 T3 DK 1049670T3 DK 99901781 T DK99901781 T DK 99901781T DK 99901781 T DK99901781 T DK 99901781T DK 1049670 T3 DK1049670 T3 DK 1049670T3
Authority
DK
Denmark
Prior art keywords
treatment
cns disorders
carboxamide derivatives
azetidine carboxamide
azetidine
Prior art date
Application number
DK99901781T
Other languages
English (en)
Inventor
David Reginald Adams
Jon Bentley
Corinna Dagmar Bodkin
Ian Anthony Cliffe
James Edward Paul Davidson
Howard Langham Mansell
Nathaniel Julius Monck
Robin Gerald Shepherd
Original Assignee
Vernalis Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9801499.6A external-priority patent/GB9801499D0/en
Priority claimed from GBGB9824458.5A external-priority patent/GB9824458D0/en
Application filed by Vernalis Res Ltd filed Critical Vernalis Res Ltd
Application granted granted Critical
Publication of DK1049670T3 publication Critical patent/DK1049670T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK99901781T 1998-01-23 1999-01-22 Azetidincarboxamidderivater til behandling af CNS-lidelser DK1049670T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9801499.6A GB9801499D0 (en) 1998-01-23 1998-01-23 Chemical compounds iii
GBGB9824458.5A GB9824458D0 (en) 1998-11-06 1998-11-06 Chemical compounds II
PCT/GB1999/000223 WO1999037613A1 (en) 1998-01-23 1999-01-22 Azetidinecarboxamide derivatives for treating cns disorders

Publications (1)

Publication Number Publication Date
DK1049670T3 true DK1049670T3 (da) 2002-11-11

Family

ID=26313009

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99901781T DK1049670T3 (da) 1998-01-23 1999-01-22 Azetidincarboxamidderivater til behandling af CNS-lidelser

Country Status (10)

Country Link
US (1) US6831078B1 (da)
EP (1) EP1049670B1 (da)
JP (1) JP4542264B2 (da)
AT (1) ATE220665T1 (da)
AU (1) AU2178099A (da)
DE (1) DE69902142T2 (da)
DK (1) DK1049670T3 (da)
ES (1) ES2181387T3 (da)
PT (1) PT1049670E (da)
WO (1) WO1999037613A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9917384D0 (en) * 1999-07-23 1999-09-22 Cerebrus Ltd Chemical compounds-III
JP5621087B2 (ja) * 2008-11-24 2014-11-05 インテグレイティブ・リサーチ・ラボラトリーズ・スウェーデン・アーベー 皮質のカテコールアミン作動性神経伝達のモジュレーターとして有用な新規な３−フェニル−アゼチジン誘導体
CN115650893A (zh) * 2022-10-24 2023-01-31 南通华祥医药科技有限公司 一种1-二苯甲基氮杂环丁烷-3-酮的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB872447A (en) * 1958-12-23 1961-07-12 Lepetit Spa 1-carbamyl-3-substituted azetidines
US4226861A (en) 1978-04-18 1980-10-07 A. H. Robins Company, Inc. N-Lower-alkyl 3-phenoxy-1-azetidinecarboxamides
IL68699A (en) * 1982-08-19 1986-08-31 Robins Co Inc A H 3-phenoxy-1-azetidine-carboxamides,their preparation and pharmaceutical compositions containing them
US4505907A (en) * 1982-09-02 1985-03-19 A. H. Robins Company, Inc. N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides
IE58943B1 (en) * 1985-02-28 1993-12-01 Robins Co Inc A H 3-Aryloxy-azetidine-carboxamides
US4956359A (en) * 1985-02-28 1990-09-11 A. H. Robins Company, Inc. 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics

Also Published As

Publication number Publication date
EP1049670A1 (en) 2000-11-08
EP1049670B1 (en) 2002-07-17
ES2181387T3 (es) 2003-02-16
US6831078B1 (en) 2004-12-14
JP2002501046A (ja) 2002-01-15
WO1999037613A1 (en) 1999-07-29
DE69902142D1 (de) 2002-08-22
ATE220665T1 (de) 2002-08-15
PT1049670E (pt) 2002-12-31
JP4542264B2 (ja) 2010-09-08
DE69902142T2 (de) 2003-01-09
AU2178099A (en) 1999-08-09

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