HUP0202062A3 - Method for making granules with masked taste and instant release of the active particle - Google Patents

Method for making granules with masked taste and instant release of the active particle

Info

Publication number
HUP0202062A3
HUP0202062A3 HU0202062A HUP0202062A HUP0202062A3 HU P0202062 A3 HUP0202062 A3 HU P0202062A3 HU 0202062 A HU0202062 A HU 0202062A HU P0202062 A HUP0202062 A HU P0202062A HU P0202062 A3 HUP0202062 A3 HU P0202062A3
Authority
HU
Hungary
Prior art keywords
active particle
instant release
making granules
masked taste
masked
Prior art date
Application number
HU0202062A
Other languages
English (en)
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Publication of HUP0202062A2 publication Critical patent/HUP0202062A2/hu
Publication of HUP0202062A3 publication Critical patent/HUP0202062A3/hu
Publication of HU229568B1 publication Critical patent/HU229568B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Seasonings (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0202062A 1999-07-08 2000-06-30 Eljárás maszkírozott ízû és azonnali hatóanyag-leadású bevont szemcsék elõállítására HU229568B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9909047A FR2795962B1 (fr) 1999-07-08 1999-07-08 Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
PCT/FR2000/001855 WO2001003672A1 (fr) 1999-07-08 2000-06-30 Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif

Publications (3)

Publication Number Publication Date
HUP0202062A2 HUP0202062A2 (hu) 2002-12-28
HUP0202062A3 true HUP0202062A3 (en) 2004-05-28
HU229568B1 HU229568B1 (hu) 2014-02-28

Family

ID=9548029

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202062A HU229568B1 (hu) 1999-07-08 2000-06-30 Eljárás maszkírozott ízû és azonnali hatóanyag-leadású bevont szemcsék elõállítására

Country Status (31)

Country Link
US (1) US6660382B2 (hu)
EP (1) EP1194125B1 (hu)
JP (1) JP4749639B2 (hu)
KR (1) KR100767928B1 (hu)
CN (1) CN1220485C (hu)
AT (1) ATE360412T1 (hu)
AU (1) AU760006B2 (hu)
BG (1) BG65615B1 (hu)
BR (1) BR0012250A (hu)
CA (1) CA2375600C (hu)
CY (1) CY1107695T1 (hu)
CZ (1) CZ300154B6 (hu)
DE (1) DE60034565T2 (hu)
DK (1) DK1194125T3 (hu)
DZ (1) DZ3257A1 (hu)
EA (1) EA003161B1 (hu)
ES (1) ES2284507T3 (hu)
FR (1) FR2795962B1 (hu)
HK (1) HK1049119B (hu)
HU (1) HU229568B1 (hu)
IL (2) IL147212A0 (hu)
MA (1) MA25426A1 (hu)
MX (1) MXPA01013354A (hu)
NO (1) NO331256B1 (hu)
NZ (1) NZ516594A (hu)
PL (1) PL201782B1 (hu)
PT (1) PT1194125E (hu)
SK (1) SK287322B6 (hu)
TR (1) TR200200013T2 (hu)
WO (1) WO2001003672A1 (hu)
ZA (1) ZA200200344B (hu)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
AU2001277230A1 (en) * 2000-08-01 2002-02-13 Inhale Therapeutic Systems, Inc. Apparatus and process to produce particles having a narrow size distribution andparticles made thereby
GB0018968D0 (en) * 2000-08-02 2000-09-20 Pfizer Ltd Particulate composition
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
DE60124895D1 (de) * 2001-07-26 2007-01-11 Ethypharm Sa Umgehüllte Allylamine oder Benzylamine enthaltende Granulate, Verfahren zur Herstellung und in der Mundhöhle dispergierbare Tabletten enthaltend die umgehüllten Granulate
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
FR2834212B1 (fr) * 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
CA2492789C (en) * 2002-07-17 2012-07-03 Eurand Pharmaceuticals Limited Process for the preparation of pharmaceutical microcapsules with enhanced taste-masking and high dissolution rate
CN1681493A (zh) * 2002-07-19 2005-10-12 兰贝克赛实验室有限公司 掩味舒马曲坦片剂及其制备方法
EP1396263A1 (en) * 2002-08-09 2004-03-10 Warner-Lambert Company Film coating for tablets and caplets
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
FR2850275B1 (fr) 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
US20040151771A1 (en) 2003-02-04 2004-08-05 Gin Jerry B. Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
JP2006525303A (ja) 2003-05-08 2006-11-09 ネクター セラピューティクス ユーケー リミティド 微粒子物質
WO2004110492A2 (en) * 2003-06-06 2004-12-23 Glaxo Group Limited Composition comprising triptans and nsaids
US20060228410A1 (en) * 2003-08-11 2006-10-12 Hubert Dumont Flavored taste-masked pharmaceutical formulation made using a one-step coating process
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (en) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
PE20070698A1 (es) * 2005-11-14 2007-08-17 Teijin Pharma Ltd Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol
JP5123517B2 (ja) * 2005-11-14 2013-01-23 帝人ファーマ株式会社 アンブロキソール口腔内速崩性錠剤
JP5405752B2 (ja) * 2007-01-31 2014-02-05 大日本住友製薬株式会社 被覆された薬物含有粒子および該粒子を含む固形製剤
DE102007019071A1 (de) * 2007-04-23 2008-10-30 Ratiopharm Gmbh Stabilisierte pharmazeutische Zusammensetzung enthaltend Pregabalin
US8703204B2 (en) 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US8309129B2 (en) 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
KR100895942B1 (ko) * 2007-05-08 2009-05-07 조선대학교산학협력단 생약 추출물을 함유하는 구강 내 속붕해성 제제 조성물 및그의 제조 방법
US9545384B2 (en) 2007-06-04 2017-01-17 Bend Research, Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate
EP2162120B1 (en) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
US9724362B2 (en) 2007-12-06 2017-08-08 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
WO2009073216A1 (en) 2007-12-06 2009-06-11 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an amine-functionalized methacrylate copolymer
JPWO2010018614A1 (ja) * 2008-08-11 2012-01-26 味の素株式会社 呈味性が改善された親水性アミノ酸含有製剤
FR2935084B1 (fr) * 2008-08-19 2011-05-06 Pancosma Sa Pour L Ind Des Produits Biochimiques Additif pour l'alimentation animale et son procede de preparation
KR101069118B1 (ko) 2008-10-22 2011-09-30 경상대학교산학협력단 장용해성 염화콜린의 제조방법 및 이의 방법에 따라 제조되는 염화콜린
CN101879141B (zh) * 2009-05-05 2013-07-17 烟台绿叶动物保健品有限公司 一种掩味替米考星胃溶颗粒制剂
WO2010150221A1 (en) 2009-06-25 2010-12-29 Wockhardt Research Centre Taste masked pharmaceutical compositions of pregabalin
EP2316433A1 (en) * 2009-10-22 2011-05-04 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi Orally disintegrating tablets of flurbiprofen
RU2602865C2 (ru) * 2009-10-26 2016-11-20 Мерк Шарп И Доум Корп. Твердые фармацевтические композиции, содержащие ингибитор интегразы
BR112012010170A2 (pt) * 2009-10-28 2016-04-12 Mcneil Ppc Inc composições de revestimento para desintegração/dissolução rápida
CN102958515A (zh) 2009-12-02 2013-03-06 阿普塔利斯制药有限公司 非索非那定微胶囊及含有非索非那定微胶囊的组合物
TR200909613A1 (tr) * 2009-12-22 2011-07-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Pregabalinin farmasötik bileşimleri.
GB2479213B (en) 2010-04-01 2013-07-10 Theravida Inc Pharmaceutical formulations for the treatment of overactive bladder
MX2013000284A (es) 2010-07-09 2013-03-18 Teijin Pharma Ltd Tableta de desintegracion intraoral.
JP4803686B2 (ja) * 2010-08-31 2011-10-26 協和発酵キリン株式会社 苦味を呈する薬物を含有する顆粒および口腔内崩壊錠
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
KR101481772B1 (ko) 2012-06-19 2015-01-14 주식회사 아리바이오 추출물을 고농도로 함유하는 과립 또는 환의 제조방법
CN102908337B (zh) 2012-10-12 2014-03-05 大连医诺生物有限公司 微囊化氨基酸组合物及其制备方法
US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them
EP3110403B1 (en) 2014-02-25 2019-11-06 Orbis Biosciences, Inc. Taste masking drug formulations
WO2015170939A1 (ko) * 2014-05-08 2015-11-12 주식회사 씨티씨바이오 클로미프라민 함유 맛 차폐된 구강 투여용 약학 제제
KR101601794B1 (ko) 2014-05-08 2016-03-10 주식회사 씨티씨바이오 클로미프라민 함유 맛 차폐된 구강 투여용 약학 제제
EP3405191A4 (en) 2016-01-20 2019-09-04 TheraVida, Inc. METHOD AND COMPOSITIONS FOR TREATING HYPERHIDROSIS
JP6919119B2 (ja) * 2017-01-23 2021-08-18 日新製薬株式会社 ３位が置換されたγ−アミノ酪酸誘導体を含有する圧縮固形医薬組成物。
FR3078630B1 (fr) 2018-03-08 2021-05-14 Karim Ioualalen Mode de formulation sous forme de solide divise hydrophobe

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
JPS62126122A (ja) 1985-11-27 1987-06-08 Showa Shinyaku Kk 表面コ−テイングされたイブプロフエン顆粒の製法
SE457326B (sv) 1986-02-14 1988-12-19 Lejus Medical Ab Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa
JPH0780754B2 (ja) 1986-08-06 1995-08-30 エーザイ株式会社 多顆粒型持続性錠剤
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
US5358717A (en) * 1989-12-22 1994-10-25 Syntex (U.S.A.) Inc. Directly-compressible naproxen or naproxen sodium compositions
JP2845342B2 (ja) * 1990-04-28 1999-01-13 大正製薬株式会社 ビタミンｄ▲下３▼誘導体含有固形製剤組成物
US5380535A (en) * 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
DE4122217C2 (de) * 1991-07-04 1997-02-13 Merz & Co Gmbh & Co Verfahren zur Herstellung mechanisch stabiler, gut zerfallender Komprimate aus kleinen wirkstoffhaltigen Formkörpern
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
TW271400B (hu) * 1992-07-30 1996-03-01 Pfizer
AUPN605795A0 (en) * 1995-10-19 1995-11-09 F.H. Faulding & Co. Limited Analgesic pharmaceutical composition
AUPO637197A0 (en) 1997-04-23 1997-05-15 F.H. Faulding & Co. Limited Taste-masked pharmaceutical compositions
KR20000069899A (ko) * 1997-01-06 2000-11-25 디. 제이. 우드, 스피겔 알렌 제이 속방성 및 미각 차폐성 약제학적 용량 형태
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
BR9813808A (pt) * 1997-12-19 2002-05-28 Smithkline Beecham Corp Processo para produção de comprimidos para dispersão na mordida
FR2785539B1 (fr) 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
US6451345B1 (en) * 2000-01-20 2002-09-17 Eurand Pharmaceuticals Ltd. Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration

Also Published As

Publication number Publication date
PL201782B1 (pl) 2009-05-29
DE60034565D1 (de) 2007-06-06
JP4749639B2 (ja) 2011-08-17
BG65615B1 (bg) 2009-03-31
EP1194125B1 (fr) 2007-04-25
KR100767928B1 (ko) 2007-10-17
BG106398A (en) 2002-09-30
FR2795962B1 (fr) 2003-05-09
TR200200013T2 (tr) 2002-06-21
ZA200200344B (en) 2003-03-26
KR20020015062A (ko) 2002-02-27
NO20016308D0 (no) 2001-12-21
JP2003504324A (ja) 2003-02-04
AU760006B2 (en) 2003-05-08
NO331256B1 (no) 2011-11-07
EP1194125A1 (fr) 2002-04-10
DE60034565T2 (de) 2007-12-27
CA2375600A1 (fr) 2001-01-18
CN1220485C (zh) 2005-09-28
DZ3257A1 (fr) 2001-01-18
WO2001003672A1 (fr) 2001-01-18
US20020098227A1 (en) 2002-07-25
DK1194125T3 (da) 2007-07-30
ATE360412T1 (de) 2007-05-15
US6660382B2 (en) 2003-12-09
EA003161B1 (ru) 2003-02-27
CZ200218A3 (cs) 2002-04-17
EA200200136A1 (ru) 2002-06-27
NZ516594A (en) 2003-11-28
CN1373658A (zh) 2002-10-09
IL147212A0 (en) 2002-08-14
MA25426A1 (fr) 2002-04-01
CZ300154B6 (cs) 2009-02-25
MXPA01013354A (es) 2002-07-09
SK19392001A3 (sk) 2002-04-04
PT1194125E (pt) 2007-07-03
HU229568B1 (hu) 2014-02-28
CA2375600C (fr) 2011-05-10
BR0012250A (pt) 2002-03-26
PL354257A1 (en) 2003-12-29
NO20016308L (no) 2001-12-21
FR2795962A1 (fr) 2001-01-12
ES2284507T3 (es) 2007-11-16
HUP0202062A2 (hu) 2002-12-28
IL147212A (en) 2007-05-15
HK1049119A1 (en) 2003-05-02
CY1107695T1 (el) 2013-04-18
HK1049119B (zh) 2006-05-12
AU5993600A (en) 2001-01-30
SK287322B6 (sk) 2010-07-07

Similar Documents

Publication Publication Date Title
HUP0202062A3 (en) Method for making granules with masked taste and instant release of the active particle
EP1242112A4 (en) PRODUCTS CONTAINING MEDICINANT SUBSTANCE PARTICLES AND PROCESS FOR PREPARING THE SAME
IL145097A0 (en) Aerodynamic projectiles and methods of making the same
HUP0200898A3 (en) Derivatives of venlafaxine and methods of preparing and using the same
TW474169U (en) Absorbent article and method for making the same
IL164851A0 (en) Process for the preparation of 7-substituted-3-quinoline and 3-quinol-4-one carbonitriles
GB9929560D0 (en) Insert and method of manufacture thereof
IL148073A0 (en) Apparatus and methods for the production of powders
AU4987700A (en) Polymerized modified particles and methods of making the same
IL136251A0 (en) Soft pellet drug composition and methods for the preparation thereof
GB9920558D0 (en) Methods for particle formation and their products
EP1183030A4 (en) PROCESS FOR THE PREPARATION AND ITS USE OF N-DESMETHYLZOPICLONE
HK1039082B (zh) 光催化劑顆粒及其製備方法
EP1296660A4 (en) PREPARATION FOR THE CONTROLLED RELEASE OF INSULIN AND ITS MANUFACTURING METHOD
ZA996060B (en) Pellet implant system for immediate and delayed release of antiparasitic drug.
GB2367103B (en) Connector and method of use of the connector
AU4218400A (en) Lyophilized solid dosage forms and methods of making
AU2001263812A1 (en) Granulated particles with masked taste
IL146808A0 (en) Methods for coating particles and particles produced thereby
HK1040421A1 (en) Ornament and method for preparation thereof
GC0000304A (en) Installation and process for the preparation of urea
PL354994A1 (en) Bio-supportive matrices, methods of making and using the same
AU1334801A (en) Low density marshmallow-like products and methods of producing the same
AU4708200A (en) Tow and process of making
EP1104803A4 (en) GRANULES AS A CARRIER MATERIAL FOR TENSIDE AND METHOD FOR THEIR PRODUCTION

Legal Events

Date Code Title Description
TH4A Erratum
MM4A Lapse of definitive patent protection due to non-payment of fees