HUP0101809A2 - 5-és 3-as típusú 17béta-hidroxi-szteroid dehidrogenáz inhibitorok és ezeket tartalmazó gyógyászati készítmények - Google Patents

5-és 3-as típusú 17béta-hidroxi-szteroid dehidrogenáz inhibitorok és ezeket tartalmazó gyógyászati készítmények

Info

Publication number
HUP0101809A2
HUP0101809A2 HU0101809A HUP0101809A HUP0101809A2 HU P0101809 A2 HUP0101809 A2 HU P0101809A2 HU 0101809 A HU0101809 A HU 0101809A HU P0101809 A HUP0101809 A HU P0101809A HU P0101809 A2 HUP0101809 A2 HU P0101809A2
Authority
HU
Hungary
Prior art keywords
type
17betha
inhibitors
methods
hydroxysteroid dehydrogenase
Prior art date
Application number
HU0101809A
Other languages
English (en)
Inventor
Alain Belanger
Sylvain Gauthier
Fernand Labrie
Van Luu-The
Yves Merand
Donald Poirier
Louis Provencher
Shankar Mohan Singh
Original Assignee
Endorecherche, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endorecherche, Inc. filed Critical Endorecherche, Inc.
Publication of HUP0101809A2 publication Critical patent/HUP0101809A2/hu
Publication of HUP0101809A3 publication Critical patent/HUP0101809A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
HU0101809A 1998-03-11 1999-03-10 Inhibitors of type 5 and type 3 17betha-hydroxysteroid dehydrogenase and methods for their use HUP0101809A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7751098P 1998-03-11 1998-03-11
US9562398P 1998-08-07 1998-08-07
PCT/CA1999/000205 WO1999046279A2 (en) 1998-03-11 1999-03-10 INHIBITORS OF TYPE 5 AND TYPE 3 17β-HYDROXYSTEROID DEHYDROGENASE AND METHODS FOR THEIR USE

Publications (2)

Publication Number Publication Date
HUP0101809A2 true HUP0101809A2 (hu) 2001-12-28
HUP0101809A3 HUP0101809A3 (en) 2002-07-29

Family

ID=26759352

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0101809A HUP0101809A3 (en) 1998-03-11 1999-03-10 Inhibitors of type 5 and type 3 17betha-hydroxysteroid dehydrogenase and methods for their use

Country Status (15)

Country Link
US (2) US6541463B1 (hu)
EP (1) EP1094798A2 (hu)
JP (1) JP2002506077A (hu)
CN (1) CN1429104A (hu)
AU (1) AU2707999A (hu)
BR (1) BR9908592A (hu)
CA (1) CA2323089A1 (hu)
HK (1) HK1053054A1 (hu)
HU (1) HUP0101809A3 (hu)
IL (1) IL128942A (hu)
MX (1) MXPA00008868A (hu)
PL (1) PL343862A1 (hu)
RU (1) RU2000125533A (hu)
TR (1) TR200002784T2 (hu)
WO (1) WO1999046279A2 (hu)

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Also Published As

Publication number Publication date
CN1429104A (zh) 2003-07-09
TR200002784T2 (tr) 2000-12-21
MXPA00008868A (es) 2003-04-25
BR9908592A (pt) 2001-04-24
IL128942A (en) 2004-07-25
US20040082556A1 (en) 2004-04-29
PL343862A1 (en) 2001-09-10
HK1053054A1 (zh) 2003-10-10
HUP0101809A3 (en) 2002-07-29
RU2000125533A (ru) 2002-10-20
WO1999046279A3 (en) 2001-02-22
JP2002506077A (ja) 2002-02-26
AU2707999A (en) 1999-09-27
CA2323089A1 (en) 1999-09-16
EP1094798A2 (en) 2001-05-02
US6541463B1 (en) 2003-04-01
WO1999046279A2 (en) 1999-09-16
IL128942A0 (en) 2000-02-17

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