HUP0004050A2 - Javított oldódású itrakonazol, eljárás ennek előállítására és ezt tartalmazó orális gyógyszerkészítmény - Google Patents

Javított oldódású itrakonazol, eljárás ennek előállítására és ezt tartalmazó orális gyógyszerkészítmény

Info

Publication number
HUP0004050A2
HUP0004050A2 HU0004050A HUP0004050A HUP0004050A2 HU P0004050 A2 HUP0004050 A2 HU P0004050A2 HU 0004050 A HU0004050 A HU 0004050A HU P0004050 A HUP0004050 A HU P0004050A HU P0004050 A2 HUP0004050 A2 HU P0004050A2
Authority
HU
Hungary
Prior art keywords
same
itraconazole
preparing
pharmaceutical composition
oral administration
Prior art date
Application number
HU0004050A
Other languages
English (en)
Inventor
Bong-Jin Cha
Su-Eon Kim
Jun-Gyo Oh
Original Assignee
Dong-A Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong-A Pharmaceutical Co., Ltd. filed Critical Dong-A Pharmaceutical Co., Ltd.
Publication of HUP0004050A2 publication Critical patent/HUP0004050A2/hu
Publication of HUP0004050A3 publication Critical patent/HUP0004050A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Abstract

A találmány tárgya javított bioavailabilitást mutató itrakonazol, aholaz itrakonazol részecske átmérője 0,5-10 mm és amorf formávalrendelkezik. A találmány tárgya továbbá eljárás 0,5-10 mm részecskeátmérőjű, amorf formájú, javított tulajdonságú itrakonazolelőállítására oly módon, hogy az itrakonazolt valamely szervesoldószerben oldják és a keveréket oldás indukálta szárításnak vetikalá. A találmány a javított oldódású itrakonazolt tartalmazógyógyszerkészítményekre is vonatkozik. Ó
HU0004050A 1997-06-16 1998-06-16 Itraconazole exhibiting improved solubility, a method of preparing the same and pharmaceutical composition for oral administration comprising the same HUP0004050A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019970024938A KR19990001564A (ko) 1997-06-16 1997-06-16 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
PCT/KR1998/000164 WO1998057967A1 (en) 1997-06-16 1998-06-16 An itraconazole exhibiting an improved solubility, a method of preparing the same and a pharmaceutical composition for oral administration comprising the same

Publications (2)

Publication Number Publication Date
HUP0004050A2 true HUP0004050A2 (hu) 2001-06-28
HUP0004050A3 HUP0004050A3 (en) 2003-03-28

Family

ID=19509733

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004050A HUP0004050A3 (en) 1997-06-16 1998-06-16 Itraconazole exhibiting improved solubility, a method of preparing the same and pharmaceutical composition for oral administration comprising the same

Country Status (17)

Country Link
US (1) US6346533B1 (hu)
EP (1) EP0991646B1 (hu)
JP (1) JP2002504930A (hu)
KR (1) KR19990001564A (hu)
CN (1) CN1129598C (hu)
AT (1) ATE216699T1 (hu)
AU (1) AU7939298A (hu)
BR (1) BR9810124A (hu)
CA (1) CA2294398A1 (hu)
DE (1) DE69805070T2 (hu)
DK (1) DK0991646T3 (hu)
ES (1) ES2177022T3 (hu)
HU (1) HUP0004050A3 (hu)
PL (1) PL338631A1 (hu)
PT (1) PT991646E (hu)
WO (1) WO1998057967A1 (hu)
YU (1) YU66799A (hu)

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CA2477923C (en) 2002-03-01 2021-02-23 University Of South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
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Also Published As

Publication number Publication date
EP0991646A1 (en) 2000-04-12
HUP0004050A3 (en) 2003-03-28
CN1129598C (zh) 2003-12-03
PL338631A1 (en) 2000-11-06
US6346533B1 (en) 2002-02-12
YU66799A (sh) 2002-06-19
JP2002504930A (ja) 2002-02-12
WO1998057967A1 (en) 1998-12-23
DE69805070D1 (de) 2002-05-29
DK0991646T3 (da) 2002-06-10
CN1262682A (zh) 2000-08-09
BR9810124A (pt) 2000-08-08
ATE216699T1 (de) 2002-05-15
AU7939298A (en) 1999-01-04
KR19990001564A (ko) 1999-01-15
ES2177022T3 (es) 2002-12-01
EP0991646B1 (en) 2002-04-24
DE69805070T2 (de) 2002-11-07
PT991646E (pt) 2002-08-30
CA2294398A1 (en) 1998-12-23

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees