BR9810124A - Um itraconazol exibindo solibilidade incrementada, o método de preparação do mesmo e a composição farmacêutica para administração oral contendo o mesmo - Google Patents

Um itraconazol exibindo solibilidade incrementada, o método de preparação do mesmo e a composição farmacêutica para administração oral contendo o mesmo

Info

Publication number
BR9810124A
BR9810124A BR9810124-2A BR9810124A BR9810124A BR 9810124 A BR9810124 A BR 9810124A BR 9810124 A BR9810124 A BR 9810124A BR 9810124 A BR9810124 A BR 9810124A
Authority
BR
Brazil
Prior art keywords
itraconazole
same
pharmaceutical composition
oral administration
administration containing
Prior art date
Application number
BR9810124-2A
Other languages
English (en)
Inventor
Bong-Jin Cha
Jun-Gyo Oh
Su-Eon Kim
Original Assignee
Dong A Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong A Pharm Co Ltd filed Critical Dong A Pharm Co Ltd
Publication of BR9810124A publication Critical patent/BR9810124A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

<B>UM ITRACONAZOL EXIBINDO SOLUBILIDADE INCREMENTADA, O MéTODO DE PREPARAçãO DO MESMO E A COMPOSIçãO FARMACêUTICA PARA ADMINISTRAçãO ORAL CONTENDO O MESMO<D>, no qual o diâmetro da partícula do itraconazol, droga insolúvel, é reduzida e cristalina, desta maneira sendo transformada de cristalina em amórfica, aumentando a solubilidade em água e da taxa de dissolução. O itraconazol melhorado é uma droga administrada via oral.
BR9810124-2A 1997-06-16 1998-06-16 Um itraconazol exibindo solibilidade incrementada, o método de preparação do mesmo e a composição farmacêutica para administração oral contendo o mesmo BR9810124A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019970024938A KR19990001564A (ko) 1997-06-16 1997-06-16 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
PCT/KR1998/000164 WO1998057967A1 (en) 1997-06-16 1998-06-16 An itraconazole exhibiting an improved solubility, a method of preparing the same and a pharmaceutical composition for oral administration comprising the same

Publications (1)

Publication Number Publication Date
BR9810124A true BR9810124A (pt) 2000-08-08

Family

ID=19509733

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9810124-2A BR9810124A (pt) 1997-06-16 1998-06-16 Um itraconazol exibindo solibilidade incrementada, o método de preparação do mesmo e a composição farmacêutica para administração oral contendo o mesmo

Country Status (17)

Country Link
US (1) US6346533B1 (pt)
EP (1) EP0991646B1 (pt)
JP (1) JP2002504930A (pt)
KR (1) KR19990001564A (pt)
CN (1) CN1129598C (pt)
AT (1) ATE216699T1 (pt)
AU (1) AU7939298A (pt)
BR (1) BR9810124A (pt)
CA (1) CA2294398A1 (pt)
DE (1) DE69805070T2 (pt)
DK (1) DK0991646T3 (pt)
ES (1) ES2177022T3 (pt)
HU (1) HUP0004050A3 (pt)
PL (1) PL338631A1 (pt)
PT (1) PT991646E (pt)
WO (1) WO1998057967A1 (pt)
YU (1) YU66799A (pt)

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US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
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Also Published As

Publication number Publication date
EP0991646B1 (en) 2002-04-24
HUP0004050A2 (hu) 2001-06-28
CN1129598C (zh) 2003-12-03
AU7939298A (en) 1999-01-04
HUP0004050A3 (en) 2003-03-28
DK0991646T3 (da) 2002-06-10
YU66799A (sh) 2002-06-19
JP2002504930A (ja) 2002-02-12
WO1998057967A1 (en) 1998-12-23
DE69805070T2 (de) 2002-11-07
US6346533B1 (en) 2002-02-12
CA2294398A1 (en) 1998-12-23
DE69805070D1 (de) 2002-05-29
PL338631A1 (en) 2000-11-06
KR19990001564A (ko) 1999-01-15
CN1262682A (zh) 2000-08-09
PT991646E (pt) 2002-08-30
ES2177022T3 (es) 2002-12-01
ATE216699T1 (de) 2002-05-15
EP0991646A1 (en) 2000-04-12

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A,9A E 10A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1986 DE 27/03/2009.