YU66799A - Itrakonazol koji pokazuje poboljšanu rastvorljivost, postupak za njegovo dobijanje i farmaceutska smesa za oralno davanje koja sadrži isti - Google Patents

Itrakonazol koji pokazuje poboljšanu rastvorljivost, postupak za njegovo dobijanje i farmaceutska smesa za oralno davanje koja sadrži isti

Info

Publication number
YU66799A
YU66799A YU66799A YU66799A YU66799A YU 66799 A YU66799 A YU 66799A YU 66799 A YU66799 A YU 66799A YU 66799 A YU66799 A YU 66799A YU 66799 A YU66799 A YU 66799A
Authority
YU
Yugoslavia
Prior art keywords
same
itraconazole
exhibiting
preparing
pharmaceutical composition
Prior art date
Application number
YU66799A
Other languages
English (en)
Inventor
Bong-Jin Cha
Jun-Go Oh
Su-Eon Kim
Original Assignee
Dong-A Pharmaceutical Co.Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong-A Pharmaceutical Co.Ltd. filed Critical Dong-A Pharmaceutical Co.Ltd.
Publication of YU66799A publication Critical patent/YU66799A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Veličina čestica itrakonazola, kao nerastvorljivog leka, je smanjena i njegov kristalinitet je preveden iz kristalnog oblika u amorfni, čime je povećana njegova rastvorljivost u vodi i brzina rastvaranja. Poboljšan itrakonazol je primenjen u leku za oralno davanje.[The particle diameter of itraconazole, insoluble drug, is reduced and crystallinity thereof is changed from crystalline into amorphous, increasing water solubility and a dissolution rate thereof . The improved itraconazole is applied to an oral adminstration drug.
YU66799A 1997-06-16 1998-06-16 Itrakonazol koji pokazuje poboljšanu rastvorljivost, postupak za njegovo dobijanje i farmaceutska smesa za oralno davanje koja sadrži isti YU66799A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019970024938A KR19990001564A (ko) 1997-06-16 1997-06-16 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제

Publications (1)

Publication Number Publication Date
YU66799A true YU66799A (sh) 2002-06-19

Family

ID=19509733

Family Applications (1)

Application Number Title Priority Date Filing Date
YU66799A YU66799A (sh) 1997-06-16 1998-06-16 Itrakonazol koji pokazuje poboljšanu rastvorljivost, postupak za njegovo dobijanje i farmaceutska smesa za oralno davanje koja sadrži isti

Country Status (17)

Country Link
US (1) US6346533B1 (sh)
EP (1) EP0991646B1 (sh)
JP (1) JP2002504930A (sh)
KR (1) KR19990001564A (sh)
CN (1) CN1129598C (sh)
AT (1) ATE216699T1 (sh)
AU (1) AU7939298A (sh)
BR (1) BR9810124A (sh)
CA (1) CA2294398A1 (sh)
DE (1) DE69805070T2 (sh)
DK (1) DK0991646T3 (sh)
ES (1) ES2177022T3 (sh)
HU (1) HUP0004050A3 (sh)
PL (1) PL338631A1 (sh)
PT (1) PT991646E (sh)
WO (1) WO1998057967A1 (sh)
YU (1) YU66799A (sh)

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Also Published As

Publication number Publication date
DK0991646T3 (da) 2002-06-10
CN1129598C (zh) 2003-12-03
CN1262682A (zh) 2000-08-09
WO1998057967A1 (en) 1998-12-23
KR19990001564A (ko) 1999-01-15
AU7939298A (en) 1999-01-04
DE69805070D1 (de) 2002-05-29
HUP0004050A3 (en) 2003-03-28
HUP0004050A2 (hu) 2001-06-28
PT991646E (pt) 2002-08-30
JP2002504930A (ja) 2002-02-12
ES2177022T3 (es) 2002-12-01
EP0991646A1 (en) 2000-04-12
PL338631A1 (en) 2000-11-06
CA2294398A1 (en) 1998-12-23
EP0991646B1 (en) 2002-04-24
BR9810124A (pt) 2000-08-08
US6346533B1 (en) 2002-02-12
DE69805070T2 (de) 2002-11-07
ATE216699T1 (de) 2002-05-15

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