HUP0000189A3 - Bicyclic aryl carboxamides pharmaceutical compositions containing them and their therapeutic use - Google Patents

Bicyclic aryl carboxamides pharmaceutical compositions containing them and their therapeutic use

Info

Publication number
HUP0000189A3
HUP0000189A3 HU0000189A HUP0000189A HUP0000189A3 HU P0000189 A3 HUP0000189 A3 HU P0000189A3 HU 0000189 A HU0000189 A HU 0000189A HU P0000189 A HUP0000189 A HU P0000189A HU P0000189 A3 HUP0000189 A3 HU P0000189A3
Authority
HU
Hungary
Prior art keywords
pharmaceutical compositions
compositions containing
therapeutic use
bicyclic aryl
aryl carboxamides
Prior art date
Application number
HU0000189A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Darwin Discovery Ltd Milton Ro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9623860.5A external-priority patent/GB9623860D0/en
Priority claimed from GBGB9708062.6A external-priority patent/GB9708062D0/en
Application filed by Darwin Discovery Ltd Milton Ro filed Critical Darwin Discovery Ltd Milton Ro
Publication of HUP0000189A2 publication Critical patent/HUP0000189A2/hu
Publication of HUP0000189A3 publication Critical patent/HUP0000189A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0000189A 1996-11-15 1997-11-17 Bicyclic aryl carboxamides pharmaceutical compositions containing them and their therapeutic use HUP0000189A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9623860.5A GB9623860D0 (en) 1996-11-15 1996-11-15 Novel compounds
GBGB9708062.6A GB9708062D0 (en) 1997-04-22 1997-04-22 Novel compounds
PCT/GB1997/003154 WO1998022460A1 (en) 1996-11-15 1997-11-17 Bicyclic aryl carboxamides and their therapeutic use

Publications (2)

Publication Number Publication Date
HUP0000189A2 HUP0000189A2 (hu) 2001-04-28
HUP0000189A3 true HUP0000189A3 (en) 2002-01-28

Family

ID=26310411

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000189A HUP0000189A3 (en) 1996-11-15 1997-11-17 Bicyclic aryl carboxamides pharmaceutical compositions containing them and their therapeutic use

Country Status (22)

Country Link
US (2) US6353010B1 (enExample)
EP (1) EP0944616B1 (enExample)
JP (1) JP2001504479A (enExample)
KR (1) KR20000053274A (enExample)
CN (1) CN1114604C (enExample)
AT (1) ATE242234T1 (enExample)
AU (1) AU726590B2 (enExample)
BR (1) BR9713507A (enExample)
CA (1) CA2268037A1 (enExample)
CZ (1) CZ158299A3 (enExample)
DE (1) DE69722656T2 (enExample)
DK (1) DK0944616T3 (enExample)
ES (1) ES2200163T3 (enExample)
HU (1) HUP0000189A3 (enExample)
ID (1) ID21698A (enExample)
IL (1) IL129337A0 (enExample)
NO (1) NO992337D0 (enExample)
NZ (1) NZ335197A (enExample)
RU (1) RU2176642C2 (enExample)
SK (1) SK283534B6 (enExample)
TR (1) TR199901730T2 (enExample)
WO (1) WO1998022460A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000198734A (ja) * 1998-12-30 2000-07-18 Pfizer Inc 胃運動性減弱および関連疾患の治療のための運動性増強薬
GB0003254D0 (en) * 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
GB0003256D0 (en) * 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
WO2002102778A1 (en) * 2001-06-15 2002-12-27 Yamanouchi Pharmaceutical Co., Ltd. Phenylpyridine carbonyl piperazine derivative
CN101745112A (zh) * 2002-07-19 2010-06-23 艾博特生物技术有限公司 TNFα相关疾病的治疗
CA2548172A1 (en) 2003-12-04 2005-06-23 Vertex Pharmaceuticals Incorporated Quinoxalines useful as inhibitors of protein kinases
JPWO2005087749A1 (ja) * 2004-03-15 2007-08-09 協和醗酵工業株式会社 2−アミノキナゾリン誘導体
KR20070114748A (ko) * 2005-02-17 2007-12-04 에이엠알 테크놀로지, 인크. Cinv 및 ibs­d를 치료하기 위한 벤족사졸카복스아미드
US7893267B2 (en) * 2005-03-14 2011-02-22 High Point Pharmaceuticals, Llc Benzazole derivatives, compositions, and methods of use as β-secretase inhibitors
BRPI0610058A2 (pt) 2005-05-16 2010-05-25 Abbott Biotech Ltd uso de inibidor de tnf para tratamento da poliartrite erosiva
CA2642610A1 (en) * 2006-02-20 2007-08-30 Astellas Pharma Inc. Amide derivative or salt thereof
US9605064B2 (en) 2006-04-10 2017-03-28 Abbvie Biotechnology Ltd Methods and compositions for treatment of skin disorders
US9624295B2 (en) 2006-04-10 2017-04-18 Abbvie Biotechnology Ltd. Uses and compositions for treatment of psoriatic arthritis
WO2008019363A2 (en) * 2006-08-07 2008-02-14 Albany Molecular Research, Inc. 2-alkylbenzoxazole carboxamides as 5ht3 modulators
JPWO2008026687A1 (ja) 2006-09-01 2010-01-21 杏林製薬株式会社 ピラゾロピリジンカルボキサミド誘導体及びそれらを含有するホスホジエステラーゼ(pde)阻害剤
EP2061786A2 (en) * 2006-09-07 2009-05-27 Biogen Idec MA Inc. Indazole derivatives as modulators of interleukin-1 receptor-associated kinase
WO2008154543A2 (en) 2007-06-11 2008-12-18 Abbott Biotechnology Ltd. Methods for treating juvenile idiopathic arthritis
CL2008001933A1 (es) 2007-06-29 2009-09-25 Millennium Pharm Inc Compuestos derivados de pirimidina, inhibidores de la raf quinasa; compuestos intermediarios; procedimiento de preparacion; composicion farmaceutica; y su uso para tratar trastornos proliferativos, cardiacos, neurodegenerativos, inflamatorios, oseos, inmunologicos enfermedad viral, entre otros.
RU2529019C2 (ru) 2009-02-27 2014-09-27 Эмбит Байосайенсиз Корпорейшн Модулирующие jak киназу хиназолиновые производные и способы их применения
CA2810024A1 (en) 2010-09-01 2012-03-08 Ambit Biosciences Corporation Quinazoline compounds and methods of use thereof
CN104428293B (zh) * 2012-06-11 2018-06-08 Ucb生物制药私人有限公司 调节TNFα的苯并咪唑类
CN104780764A (zh) * 2012-09-05 2015-07-15 拜尔农作物科学股份公司 取代的2-酰氨基苯并咪唑、2-酰氨基苯并噁唑和2-酰氨基苯并噻唑或其盐作为活性物质对抗非生物植物胁迫的用途
CN108440333A (zh) * 2018-03-29 2018-08-24 江苏道博化工有限公司 分散染料中间体的合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50140442A (enExample) 1974-04-16 1975-11-11
JPS59155357A (ja) 1983-02-14 1984-09-04 ユ−エスヴイ−・フア−マシユ−テイカル・コ−ポレ−シヨン ベンゾ複素環状カルバメイト
DE3835660A1 (de) * 1988-03-25 1989-10-12 Bayer Ag 7-substituierte 2-carbonamido-benzthiazol-3-oxide
DE4014937A1 (de) 1990-05-10 1991-11-14 Bayer Ag 2,3-disubstituierte chinoxaline als leistungsfoerderer fuer tiere
GB9219634D0 (en) 1992-09-16 1992-10-28 Ici Plc Heterocyclic compounds
GB9219632D0 (en) 1992-09-16 1992-10-28 Ici Plc Heterocyclic compounds
CA2144763A1 (en) 1992-10-14 1994-04-28 George D. Hartman Fibrinogen receptor antagonists
DE4237617A1 (de) 1992-11-06 1994-05-11 Bayer Ag Verwendung von substituierten Benzimidazolen
GB9301660D0 (en) 1993-01-28 1993-03-17 Smithkline Beecham Plc Pharmaceuticals
GB9306578D0 (en) 1993-03-30 1993-05-26 Merck Sharp & Dohme Therapeutic agents
DE59508773D1 (de) * 1994-07-22 2000-11-09 Byk Gulden Lomberg Chem Fab Dihydrobenzofurane
US6083961A (en) 1994-08-03 2000-07-04 Fujisawa Pharmaceutical Co., Ltd. Benzimidazole compounds as bradykinin antagonists
US5665737B1 (en) 1994-10-12 1999-02-16 Euro Celtique Sa Substituted benzoxazoles
EP0785927B1 (en) * 1994-10-12 2003-08-27 Euroceltique S.A. Novel benzoxazoles

Also Published As

Publication number Publication date
NO992337L (no) 1999-05-14
AU4960297A (en) 1998-06-10
EP0944616A1 (en) 1999-09-29
DE69722656T2 (de) 2004-05-13
CA2268037A1 (en) 1998-05-28
US20020094987A1 (en) 2002-07-18
CN1237168A (zh) 1999-12-01
AU726590B2 (en) 2000-11-09
CZ158299A3 (cs) 1999-09-15
RU2176642C2 (ru) 2001-12-10
DK0944616T3 (da) 2003-09-29
ES2200163T3 (es) 2004-03-01
DE69722656D1 (de) 2003-07-10
SK64499A3 (en) 2000-03-13
NO992337D0 (no) 1999-05-14
ID21698A (id) 1999-07-15
EP0944616B1 (en) 2003-06-04
KR20000053274A (ko) 2000-08-25
WO1998022460A1 (en) 1998-05-28
ATE242234T1 (de) 2003-06-15
US6353010B1 (en) 2002-03-05
JP2001504479A (ja) 2001-04-03
NZ335197A (en) 2000-11-24
SK283534B6 (sk) 2003-09-11
TR199901730T2 (xx) 1999-09-21
HUP0000189A2 (hu) 2001-04-28
CN1114604C (zh) 2003-07-16
IL129337A0 (en) 2000-02-17
BR9713507A (pt) 2000-02-29

Similar Documents

Publication Publication Date Title
HUP0000189A3 (en) Bicyclic aryl carboxamides pharmaceutical compositions containing them and their therapeutic use
EG24144A (en) Disubstituted bicyclic heterocycles their preparation and their use as medicaments
HUP0100042A3 (en) Benzofuran carboxamides medicaments containing the same and their therapeutic use
IL121236A0 (en) Cycloalkano-pyridines their preparation and pharmaceutical compositions containing them
HUP0300836A3 (en) Oral pharmaceutical compositions containing taxanes and methods of treatment employing the same
HU9502918D0 (en) Pharmaceutical composition of antihypertriglyceridemic activity
IL113123A (en) Mono-or bicyclic compounds their preparation and pharmaceutical compositions containing them
ZA9711129B (en) New analogues of camptothecin their medical application and the pharmaceutical substances that contain them
HUP0003244A3 (en) Novel triptolide derivatives useful in the treatment of autoimmune diseases and pharmaceutical compositions thereof
EP0489102A4 (en) Pharmaceutical compositions containing aromatic polymers and therapeutic methods using the same
IL164513A0 (en) Pyrazolopyrimidines, pharmaceutical compositions containing them, and their use in the preparation of medicaments
IL121329A (en) Pharmaceutical composition for the treatment of cancer comprising somatostatin2 and other peptides
IL117395A0 (en) Bicyclic compounds preparation thereof and use in pharmaceutical compositions
IL113415A0 (en) Dihydrodibenzoquinolinediones their preparation and use and pharmaceutical compositions containing them
IL114161A0 (en) Amido- quinoxalinediones pharmaceutical compositions containing them and their use
IL115882A0 (en) Oxazolyl-and thiazolylimidazo-benzo-and thienodiazepines their manufacture and pharmaceutical compositions containing them
ZA951789B (en) Pharmaceutical materials and methods of administration
ZA9710344B (en) Bicyclic aryl carboxamides and their therapeutic use
HK1022696A (en) Bicyclic aryl carboxamides and their therapeutic use
GB9523066D0 (en) Compounds and their therapeutic use
GB9616504D0 (en) Therapeutic product and its use
GB9621314D0 (en) Substances and their therapeutic use
GB9609521D0 (en) Substances and their therapeutic use
AU1544597A (en) Gastro-resistant pharmaceutical formulations containing colostrum and the use of colostrum for the treatment of insomnia
IL129891A0 (en) New analogues of camptothecin their use as medicaments and the pharmaceutical compositions containing them