HUE067225T2 - Mielofibrózis kezelésére szolgáló készítmények - Google Patents
Mielofibrózis kezelésére szolgáló készítményekInfo
- Publication number
- HUE067225T2 HUE067225T2 HUE17835212A HUE17835212A HUE067225T2 HU E067225 T2 HUE067225 T2 HU E067225T2 HU E17835212 A HUE17835212 A HU E17835212A HU E17835212 A HUE17835212 A HU E17835212A HU E067225 T2 HUE067225 T2 HU E067225T2
- Authority
- HU
- Hungary
- Prior art keywords
- compositions
- treating myelofibrosis
- myelofibrosis
- treating
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 206010028537 myelofibrosis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662367289P | 2016-07-27 | 2016-07-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE067225T2 true HUE067225T2 (hu) | 2024-10-28 |
Family
ID=61017458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17835212A HUE067225T2 (hu) | 2016-07-27 | 2017-07-26 | Mielofibrózis kezelésére szolgáló készítmények |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US20180050085A1 (https=) |
| EP (1) | EP3490582B1 (https=) |
| JP (2) | JP7264580B2 (https=) |
| KR (1) | KR20190040972A (https=) |
| CN (1) | CN109789184A (https=) |
| AU (1) | AU2017302282B2 (https=) |
| BR (1) | BR112019001615A2 (https=) |
| CA (1) | CA3031909A1 (https=) |
| DK (1) | DK3490582T3 (https=) |
| EA (1) | EA201990226A1 (https=) |
| ES (1) | ES2984470T3 (https=) |
| FI (1) | FI3490582T3 (https=) |
| HR (1) | HRP20240974T1 (https=) |
| HU (1) | HUE067225T2 (https=) |
| LT (1) | LT3490582T (https=) |
| MA (1) | MA45811A (https=) |
| MX (1) | MX2019001043A (https=) |
| PL (1) | PL3490582T3 (https=) |
| PT (1) | PT3490582T (https=) |
| RS (1) | RS65735B1 (https=) |
| SI (1) | SI3490582T1 (https=) |
| SM (1) | SMT202400299T1 (https=) |
| WO (1) | WO2018022762A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10195249B2 (en) | 2012-11-02 | 2019-02-05 | Celgene Corporation | Activin-ActRII antagonists and uses for treating bone and other disorders |
| MA41052A (fr) | 2014-10-09 | 2017-08-15 | Celgene Corp | Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii |
| JP2018501307A (ja) | 2014-12-03 | 2018-01-18 | セルジーン コーポレイション | アクチビン−ActRIIアンタゴニスト及び貧血を治療するための使用 |
| CN108350057A (zh) | 2015-05-20 | 2018-07-31 | 细胞基因公司 | 使用II型活化素受体配体阱的用于β-地中海贫血的体外细胞培养方法 |
| EP3380121B1 (en) | 2015-11-23 | 2023-12-20 | Acceleron Pharma Inc. | Actrii antagonist for use in treating eye disorders |
| MA45811A (fr) | 2016-07-27 | 2019-06-05 | Acceleron Pharma Inc | Méthodes et compositions de traitement de maladie. |
| NZ754161A (en) | 2016-11-10 | 2025-11-28 | Keros Therapeutics Inc | Activin receptor type iia variants and methods of use thereof |
| PL3638243T3 (pl) * | 2017-06-14 | 2025-02-10 | Celgene Corporation | Sposoby leczenia mielofibrozy związanej z nowotworem mieloproliferacyjnym i niedokrwistości |
| CA3082146A1 (en) | 2017-11-09 | 2019-05-16 | Keros Therapeutics, Inc. | Activin receptor type iia variants and methods of use thereof |
| IL320014A (en) | 2018-01-12 | 2025-06-01 | Keros Therapeutics Inc | Activin receptor type iib variants and methods of use thereof |
| KR20250133994A (ko) | 2018-05-09 | 2025-09-09 | 케로스 테라퓨틱스, 인크. | 액티빈 수용체 유형 iia 변이체 및 그의 사용 방법 |
| EP4041243A4 (en) * | 2019-09-27 | 2023-10-18 | Disc Medicine, Inc. | METHODS OF TREATMENT OF ANEMIA OF CHRONIC DISEASE |
| US20220372135A1 (en) * | 2019-09-27 | 2022-11-24 | Disc Medicine, Inc. | Methods for treating myelofibrosis and related conditions |
| US12441707B2 (en) | 2019-12-30 | 2025-10-14 | Tyra Biosciences, Inc. | Indazole compounds |
| WO2021189019A1 (en) | 2020-03-20 | 2021-09-23 | Keros Therapeutics, Inc. | Activin receptor type ii chimeras and methods of use thereof |
| WO2021189010A1 (en) | 2020-03-20 | 2021-09-23 | Keros Therapeutics, Inc. | Methods of using activin receptor type iib variants |
| US20230181690A1 (en) * | 2020-04-13 | 2023-06-15 | Celgene Corporation | Methods for treating anemia using an actriib ligand trap and fedratinib |
| KR20230012539A (ko) | 2020-05-13 | 2023-01-26 | 디스크 메디슨, 인크. | 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체 |
| CA3177632A1 (en) * | 2020-05-15 | 2021-11-18 | Melih ACAR | Methods and compositions for treating anemia using actriib ligand traps and mtor inhibitors |
| US12186370B1 (en) | 2020-11-05 | 2025-01-07 | Celgene Corporation | ACTRIIB ligand trap compositions and uses thereof |
| KR20240051971A (ko) * | 2021-08-19 | 2024-04-22 | 케로스 테라퓨틱스, 인크. | 액티빈 수용체 ii형 신호전달 억제제를 이용한 방법 |
| US20250041385A1 (en) * | 2021-12-10 | 2025-02-06 | Biogen Ma Inc. | Modified actrii proteins and methods of use thereof |
| WO2025184284A1 (en) * | 2024-02-27 | 2025-09-04 | Keros Therapeutics, Inc. | Methods of using activin receptor type ii signaling inhibitors |
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- 2017-07-26 EP EP17835212.6A patent/EP3490582B1/en active Active
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- 2017-07-26 LT LTEPPCT/US2017/043967T patent/LT3490582T/lt unknown
- 2017-07-26 PT PT178352126T patent/PT3490582T/pt unknown
- 2017-07-26 PL PL17835212.6T patent/PL3490582T3/pl unknown
- 2017-07-26 HR HRP20240974TT patent/HRP20240974T1/hr unknown
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- 2017-07-26 SI SI201731537T patent/SI3490582T1/sl unknown
- 2017-07-26 WO PCT/US2017/043967 patent/WO2018022762A1/en not_active Ceased
- 2017-07-26 SM SM20240299T patent/SMT202400299T1/it unknown
- 2017-07-26 JP JP2019503972A patent/JP7264580B2/ja active Active
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- 2017-07-26 RS RS20240798A patent/RS65735B1/sr unknown
- 2017-07-26 CN CN201780057961.8A patent/CN109789184A/zh active Pending
- 2017-07-26 DK DK17835212.6T patent/DK3490582T3/da active
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- 2017-07-26 HU HUE17835212A patent/HUE067225T2/hu unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| JP7264580B2 (ja) | 2023-04-25 |
| PL3490582T3 (pl) | 2024-09-23 |
| RS65735B1 (sr) | 2024-08-30 |
| CN109789184A (zh) | 2019-05-21 |
| JP2019522022A (ja) | 2019-08-08 |
| MA45811A (fr) | 2019-06-05 |
| US20250222069A1 (en) | 2025-07-10 |
| US20180050085A1 (en) | 2018-02-22 |
| DK3490582T3 (da) | 2024-07-29 |
| WO2018022762A1 (en) | 2018-02-01 |
| EP3490582A4 (en) | 2020-04-01 |
| BR112019001615A2 (pt) | 2019-04-30 |
| LT3490582T (lt) | 2024-07-25 |
| US12194076B2 (en) | 2025-01-14 |
| CA3031909A1 (en) | 2018-02-01 |
| PT3490582T (pt) | 2024-08-21 |
| ES2984470T3 (es) | 2024-10-29 |
| AU2017302282A1 (en) | 2019-02-07 |
| JP2023014373A (ja) | 2023-01-26 |
| EA201990226A1 (ru) | 2019-08-30 |
| HRP20240974T1 (hr) | 2024-10-25 |
| EP3490582A1 (en) | 2019-06-05 |
| SMT202400299T1 (it) | 2024-09-16 |
| FI3490582T3 (fi) | 2024-08-01 |
| SI3490582T1 (sl) | 2024-09-30 |
| MX2019001043A (es) | 2019-09-26 |
| AU2017302282B2 (en) | 2024-07-25 |
| KR20190040972A (ko) | 2019-04-19 |
| EP3490582B1 (en) | 2024-06-12 |
| US20210322514A1 (en) | 2021-10-21 |
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