HUE054032T2 - TTFIELD (daganatkezelési mezõ) kezelés a fejen lévõ elektródhelyek optimalizálásával MRI alapú vezetõképességi mérések alapján - Google Patents
TTFIELD (daganatkezelési mezõ) kezelés a fejen lévõ elektródhelyek optimalizálásával MRI alapú vezetõképességi mérések alapjánInfo
- Publication number
- HUE054032T2 HUE054032T2 HUE16795424A HUE16795424A HUE054032T2 HU E054032 T2 HUE054032 T2 HU E054032T2 HU E16795424 A HUE16795424 A HU E16795424A HU E16795424 A HUE16795424 A HU E16795424A HU E054032 T2 HUE054032 T2 HU E054032T2
- Authority
- HU
- Hungary
- Prior art keywords
- mri
- optimization
- conductivity measurements
- electrode positions
- ttfield
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
- A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0531—Measuring skin impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
- A61B5/4064—Evaluating the brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T11/00—2D [Two Dimensional] image generation
- G06T11/003—Reconstruction from projections, e.g. tomography
- G06T11/005—Specific pre-processing for tomographic reconstruction, e.g. calibration, source positioning, rebinning, scatter correction, retrospective gating
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T11/00—2D [Two Dimensional] image generation
- G06T11/003—Reconstruction from projections, e.g. tomography
- G06T11/008—Specific post-processing after tomographic reconstruction, e.g. voxelisation, metal artifact correction
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/30—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10072—Tomographic images
- G06T2207/10088—Magnetic resonance imaging [MRI]
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30016—Brain
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Radiology & Medical Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- High Energy & Nuclear Physics (AREA)
- Oncology (AREA)
- Developmental Disabilities (AREA)
- Psychiatry (AREA)
- Social Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Physiology (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Electrotherapy Devices (AREA)
- Cold Cathode And The Manufacture (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562247314P | 2015-10-28 | 2015-10-28 | |
US201662294372P | 2016-02-12 | 2016-02-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE054032T2 true HUE054032T2 (hu) | 2021-08-30 |
Family
ID=57321363
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE21155810A HUE062370T2 (hu) | 2015-10-28 | 2016-10-28 | TTFIELD (tumorkezelõ mezõk) kezelés elektróda helyzetének optimalizálására a fejnél MRI alapú vezetõképességi mérések alapján |
HUE16795424A HUE054032T2 (hu) | 2015-10-28 | 2016-10-28 | TTFIELD (daganatkezelési mezõ) kezelés a fejen lévõ elektródhelyek optimalizálásával MRI alapú vezetõképességi mérések alapján |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE21155810A HUE062370T2 (hu) | 2015-10-28 | 2016-10-28 | TTFIELD (tumorkezelõ mezõk) kezelés elektróda helyzetének optimalizálására a fejnél MRI alapú vezetõképességi mérések alapján |
Country Status (13)
Country | Link |
---|---|
US (3) | US10188851B2 (hu) |
EP (2) | EP3838338B1 (hu) |
JP (5) | JP7183045B2 (hu) |
KR (3) | KR20180072811A (hu) |
CN (2) | CN108348761B (hu) |
CA (1) | CA3003370A1 (hu) |
DK (2) | DK3838338T3 (hu) |
ES (2) | ES2953093T3 (hu) |
FI (1) | FI3838338T3 (hu) |
HU (2) | HUE062370T2 (hu) |
PL (2) | PL3838338T3 (hu) |
PT (1) | PT3368152T (hu) |
WO (1) | WO2017072706A1 (hu) |
Families Citing this family (119)
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WO2013166416A1 (en) * | 2012-05-04 | 2013-11-07 | The Regents Of The University Of Michigan | Mean diffusivity measurement corrections for gradient non-linearity |
US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
US10943350B2 (en) * | 2015-02-25 | 2021-03-09 | London Health Science Center Research Inc. | Automated segmentation of histological sections for vasculature quantification |
US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
CA3029468A1 (en) | 2016-06-30 | 2018-01-04 | Zeev Bomzon | Arrays for longitudinal delivery of ttfields to a body |
US11446487B2 (en) | 2016-09-23 | 2022-09-20 | Beth Israel Deaconess Medical Center, Inc. | System and methods for cancer treatment using alternating electric fields |
AU2017377003B2 (en) | 2016-12-13 | 2022-05-19 | Novocure Gmbh | Treating patients with TTFields with the electrode positions optimized using deformable templates |
CA3049949C (en) | 2017-01-19 | 2024-04-23 | Novocure Limited | System for viewing cell cultures under a microscope whilst applying tumor treating fields |
CA3056694C (en) * | 2017-05-18 | 2022-01-18 | Brainlab Ag | Determining a clinical target volume |
US11986319B2 (en) | 2017-08-25 | 2024-05-21 | NEUROPHET Inc. | Patch guide method and program |
KR101950815B1 (ko) * | 2017-08-25 | 2019-02-21 | 뉴로핏 주식회사 | 패치 가이드 방법 및 프로그램 |
KR101995900B1 (ko) * | 2017-09-11 | 2019-07-04 | 뉴로핏 주식회사 | 3차원 뇌지도 생성 방법 및 프로그램 |
WO2019060298A1 (en) | 2017-09-19 | 2019-03-28 | Neuroenhancement Lab, LLC | METHOD AND APPARATUS FOR NEURO-ACTIVATION |
US11338135B2 (en) | 2017-10-23 | 2022-05-24 | Cardiac Pacemakers, Inc. | Medical devices for cancer therapy with electric field shaping elements |
US11717686B2 (en) | 2017-12-04 | 2023-08-08 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to facilitate learning and performance |
EP3731749A4 (en) | 2017-12-31 | 2022-07-27 | Neuroenhancement Lab, LLC | NEURO-ACTIVATION SYSTEM AND METHOD FOR ENHANCING EMOTIONAL RESPONSE |
US10953209B2 (en) | 2018-03-28 | 2021-03-23 | Board Of Regents Of The University Of Texas System | Treating tumors using TTFields combined with a PARP inhibitor |
WO2019197973A1 (en) | 2018-04-09 | 2019-10-17 | Moshe Giladi | Treating tumors with ttfields and an aurora kinase inhibitor |
WO2019197999A1 (en) * | 2018-04-10 | 2019-10-17 | Zeev Bomzon | Low frequency (<1 mhz) ac conductivity estimates derived from two mri images having different repetition times |
US11364361B2 (en) | 2018-04-20 | 2022-06-21 | Neuroenhancement Lab, LLC | System and method for inducing sleep by transplanting mental states |
ES2943672T3 (es) | 2018-07-03 | 2023-06-15 | Univ Leland Stanford Junior | Uso de campos eléctricos alternos para aumentar la permeabilidad de la membrana celular |
WO2020009306A1 (ko) * | 2018-07-03 | 2020-01-09 | 고려대학교 산학협력단 | 최적화 알고리즘을 이용한 전기장 암치료장치 및 방법 |
KR102104961B1 (ko) | 2018-07-03 | 2020-04-27 | 고려대학교산학협력단 | 최적화 알고리즘을 이용한 전기장 암치료장치 |
US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
BR112020025692A2 (pt) | 2018-07-10 | 2021-03-16 | Novocure Gmbh | Inibição de infecção viral usando campos elétricos alternados |
JP7384895B2 (ja) * | 2018-07-17 | 2023-11-21 | ディグニティー ヘルス | 交流電界生成を使用した癌腫治療のためのシステム及び方法 |
CA3103075A1 (en) * | 2018-07-18 | 2020-01-23 | Novocure Gmbh | Using power loss density and related measures to quantify the dose of tumor treating fields (ttfields) |
DK3892219T3 (da) | 2018-08-23 | 2022-06-27 | Novocure Gmbh | Anvendelse af elektriske vekseltrømsfelter til forøgelse af permeabilitet af blodhjernebarrieren |
US11623085B2 (en) * | 2018-08-29 | 2023-04-11 | Regents Of The University Of Minnesota | Devices and methods for treatment of tumors using electromagnetic signal |
US11160977B2 (en) | 2018-09-04 | 2021-11-02 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the infratentorial brain |
US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
US11020585B2 (en) | 2018-09-07 | 2021-06-01 | Novocure Gmbh | Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells |
CN113382683A (zh) | 2018-09-14 | 2021-09-10 | 纽罗因恒思蒙特实验有限责任公司 | 改善睡眠的系统和方法 |
CN112822981A (zh) | 2018-10-09 | 2021-05-18 | 皇家飞利浦有限公司 | 自动eeg传感器配准 |
PL3984590T3 (pl) * | 2018-10-15 | 2023-05-02 | Novocure Gmbh | Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu |
US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
EP4019080A1 (en) | 2018-11-19 | 2022-06-29 | Novocure GmbH | Arrays for delivering tumor treating fields (ttfields) with selectively addressable sub-elements |
WO2020110050A1 (en) | 2018-11-29 | 2020-06-04 | Novocure Gmbh | Enhanced-flexibility transducer arrays for delivering ttfields (tumor treating fields) |
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WO2020144582A1 (en) * | 2019-01-08 | 2020-07-16 | Novocure Gmbh | Evaluating quality of segmentation of an image into different types of tissue for planning treatment using tumor treating fields (ttfields) |
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JP7250951B2 (ja) | 2019-04-17 | 2023-04-03 | ノボキュア ゲーエムベーハー | 隔離性を損なうことなく、隔離されたシステムからデータをアップロードすること |
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JP2022533410A (ja) * | 2019-05-20 | 2022-07-22 | ニューロエレクトリクス ユーエスエー コーポレーション | 標的神経刺激を使用して腫瘍を治療するためのシステムおよび方法 |
CN110119586B (zh) * | 2019-05-21 | 2023-02-28 | 中煤科工集团西安研究院有限公司 | 轴向电导率各向异性瞬变电磁三分量三维fdtd正演方法 |
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