HUE033494T2 - Bifenilszulfonamid endotelin és angiotenzin-ll receptor antagonista glomeruloszklerozis kezelésére - Google Patents
Bifenilszulfonamid endotelin és angiotenzin-ll receptor antagonista glomeruloszklerozis kezelésére Download PDFInfo
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- HUE033494T2 HUE033494T2 HUE14155459A HUE14155459A HUE033494T2 HU E033494 T2 HUE033494 T2 HU E033494T2 HU E14155459 A HUE14155459 A HU E14155459A HU E14155459 A HUE14155459 A HU E14155459A HU E033494 T2 HUE033494 T2 HU E033494T2
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K9/2022—Organic macromolecular compounds
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- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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Claims (2)
- S:mf38iMí«í Ipiívpomok 1. (!) képístü «sgyöfstííl 'y^W öyógysxefésietaeg óStogédhatö sö|a giomert-ioszkferáKss ksx^jésépn iörténb aikp^masra.
- 2. (0 képí$tü ^gyöfetm va9F Sybgy«2é:!'ésx®titeg sífogadhatö sóiénak alkalmazásé gtofMrtílöáSfc*M&£& ksxeSésáfö afekriíss gyégyazsrsiöáiikáséfeán.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16544709P | 2009-03-31 | 2009-03-31 | |
US16541909P | 2009-03-31 | 2009-03-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE033494T2 true HUE033494T2 (hu) | 2017-12-28 |
Family
ID=42828649
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE17157697A HUE049450T2 (hu) | 2009-03-31 | 2010-03-29 | Endotelin és angiotenzin II receptor antagonista bifenilszulfonamid glomeruloszklerózis és IgA által kiváltott nefropátia kezelésére |
HUE14155459A HUE033494T2 (hu) | 2009-03-31 | 2010-03-29 | Bifenilszulfonamid endotelin és angiotenzin-ll receptor antagonista glomeruloszklerozis kezelésére |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE17157697A HUE049450T2 (hu) | 2009-03-31 | 2010-03-29 | Endotelin és angiotenzin II receptor antagonista bifenilszulfonamid glomeruloszklerózis és IgA által kiváltott nefropátia kezelésére |
Country Status (15)
Country | Link |
---|---|
US (4) | US20140142149A1 (hu) |
EP (4) | EP3708163A1 (hu) |
JP (3) | JP2012522058A (hu) |
CN (2) | CN102421434A (hu) |
CY (2) | CY1119232T1 (hu) |
DK (2) | DK3222277T3 (hu) |
ES (2) | ES2636087T3 (hu) |
HK (1) | HK1244687A1 (hu) |
HR (2) | HRP20171197T1 (hu) |
HU (2) | HUE049450T2 (hu) |
LT (2) | LT3222277T (hu) |
PL (2) | PL2732818T3 (hu) |
PT (2) | PT2732818T (hu) |
SI (2) | SI3222277T1 (hu) |
WO (1) | WO2010114801A1 (hu) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
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US20130177500A1 (en) | 2010-07-23 | 2013-07-11 | Trustee Of Boston University | Anti-despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery |
AR083417A1 (es) | 2010-10-14 | 2013-02-21 | Novartis Ag | Composiciones farmaceuticas que contienen un dgat1 inhibidor |
US20130022551A1 (en) * | 2011-07-22 | 2013-01-24 | Trustees Of Boston University | DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS |
JP6203182B2 (ja) * | 2011-10-17 | 2017-09-27 | レクシコン ファーマシューティカルズ インコーポレイテッド | (s)−エチル2−アミノ−3−(4−(2−アミノ−6−((r)−1−(4−クロロ−2−(3−メチル−1h−ピラゾール−1−イル)フェニル)−2,2,2−トリフルオロエトキシ)ピリミジン−4−イル)フェニル)プロパノエートの固形剤 |
PE20221914A1 (es) | 2011-12-28 | 2022-12-23 | Global Blood Therapeutics Inc | Compuestos de benzaldehido sustituidos y metodos para su uso en incrementar la oxigenacion del tejido |
EP2797597B1 (en) | 2011-12-28 | 2020-02-26 | Global Blood Therapeutics, Inc. | Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation |
EP2875359A4 (en) | 2012-03-30 | 2015-08-19 | Charles R Drew University Of Medicine And Science | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLISM SYNDROME DISEASES |
US20140271923A1 (en) | 2013-03-14 | 2014-09-18 | Christopher Brian Reid | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions |
US9458139B2 (en) | 2013-03-15 | 2016-10-04 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
AU2014237330A1 (en) | 2013-03-15 | 2015-09-17 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
CN112500338A (zh) | 2013-03-15 | 2021-03-16 | 全球血液疗法股份有限公司 | 化合物及其用于调节血红蛋白的用途 |
KR101971385B1 (ko) | 2013-03-15 | 2019-04-22 | 글로벌 블러드 테라퓨틱스, 인크. | 헤모글로빈 조정을 위한 화합물 및 이의 용도 |
US8952171B2 (en) | 2013-03-15 | 2015-02-10 | Global Blood Therapeutics, Inc. | Compounds and uses thereof for the modulation of hemoglobin |
CN114404414A (zh) | 2013-06-13 | 2022-04-29 | 阿克比治疗有限公司 | 用于治疗贫血症的组合物和方法 |
EA201992707A1 (ru) | 2013-11-18 | 2020-06-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
WO2015119848A1 (en) * | 2014-02-05 | 2015-08-13 | Merck Sharp & Dohme Corp. | Tablet formulation for cgrp-active compounds |
AU2015214182B2 (en) | 2014-02-07 | 2020-04-30 | Global Blood Therapeutics, Inc. | Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde |
CN104367576A (zh) * | 2014-10-24 | 2015-02-25 | 南方医科大学南方医院 | 化合物icg-001在制备治疗高血压的药物中的用途 |
WO2017035249A1 (en) | 2015-08-24 | 2017-03-02 | Trustees Of Boston University | ANTI-DEspR MONOCLONAL ANTIBODY TARGETED THERAPY AND IMAGING FOR CANCER AND STROKE |
MA43373A (fr) | 2015-12-04 | 2018-10-10 | Global Blood Therapeutics Inc | Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde |
TWI663160B (zh) | 2016-05-12 | 2019-06-21 | 全球血液治療公司 | 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法 |
TW202332423A (zh) * | 2016-10-12 | 2023-08-16 | 美商全球血液治療公司 | 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑 |
EP3525784A1 (en) * | 2016-10-13 | 2019-08-21 | Retrophin, Inc. | Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders |
CA3061479A1 (en) * | 2017-04-25 | 2018-11-01 | Proteus Digital Health, Inc. | Lisinopril compositions with an ingestible event marker |
CN111356475A (zh) | 2017-09-18 | 2020-06-30 | 波士顿大学董事会 | 用于治疗NETosis和中性粒细胞激活的方法 |
WO2019241609A1 (en) | 2018-06-15 | 2019-12-19 | Trustees Of Boston University | Polypeptide compositions and methods for site-specific targeting of therapeutic agents |
WO2020072377A1 (en) | 2018-10-01 | 2020-04-09 | Global Blood Therapeutics, Inc. | Modulators of hemoglobin for the treatment of sickle cell disease |
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MA54542A (fr) * | 2018-12-21 | 2021-10-27 | Travere Therapeutics Inc | Compositions de sparsentan amorphe |
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US793898A (en) | 1905-03-01 | 1905-07-04 | William Mcintosh | Locomotive-tender frame. |
US1395298A (en) | 1919-11-20 | 1921-11-01 | Walter H Richman | Container |
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US6586438B2 (en) | 1999-11-03 | 2003-07-01 | Bristol-Myers Squibb Co. | Antidiabetic formulation and method |
DE60030764T2 (de) * | 1999-12-15 | 2007-09-13 | Bristol-Myers Squibb Co. | Biphenyl - sulfonamide als duale angiotensin - endothelin - rezeptor - antagonisten |
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