LT2732818T - Endotelino ir angiotenzino ii receptorių bifenilsulfonamido antagonistai, skirti glomerulosklerozės gydymui - Google Patents

Endotelino ir angiotenzino ii receptorių bifenilsulfonamido antagonistai, skirti glomerulosklerozės gydymui

Info

Publication number
LT2732818T
LT2732818T LTEP14155459.2T LT14155459T LT2732818T LT 2732818 T LT2732818 T LT 2732818T LT 14155459 T LT14155459 T LT 14155459T LT 2732818 T LT2732818 T LT 2732818T
Authority
LT
Lithuania
Prior art keywords
biphenylsulfonamide
endothelin
angiotensin
receptor antagonist
glomerulosclerosis
Prior art date
Application number
LTEP14155459.2T
Other languages
English (en)
Inventor
Jinkun Zhang
Zofia E Dziewanowska
Rene Belder
Ian Henderson
Joseph B Bogardus
Zhaoying Zhang
Original Assignee
Ligand Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42828649&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2732818(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ligand Pharmaceuticals Inc. filed Critical Ligand Pharmaceuticals Inc.
Publication of LT2732818T publication Critical patent/LT2732818T/lt

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
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    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • A61K9/2022—Organic macromolecular compounds
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  • Hematology (AREA)
  • Dermatology (AREA)
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  • Obesity (AREA)
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LTEP14155459.2T 2009-03-31 2010-03-29 Endotelino ir angiotenzino ii receptorių bifenilsulfonamido antagonistai, skirti glomerulosklerozės gydymui LT2732818T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16544709P 2009-03-31 2009-03-31
US16541909P 2009-03-31 2009-03-31

Publications (1)

Publication Number Publication Date
LT2732818T true LT2732818T (lt) 2017-09-25

Family

ID=42828649

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP17157697.8T LT3222277T (lt) 2009-03-31 2010-03-29 Bifenilsulfonamido endotelino ir angiotenzino ii receptoriaus antagonistas, skirtas glomerulosklerozės ir iga indukuotos nefropatijos gydymui
LTEP14155459.2T LT2732818T (lt) 2009-03-31 2010-03-29 Endotelino ir angiotenzino ii receptorių bifenilsulfonamido antagonistai, skirti glomerulosklerozės gydymui

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP17157697.8T LT3222277T (lt) 2009-03-31 2010-03-29 Bifenilsulfonamido endotelino ir angiotenzino ii receptoriaus antagonistas, skirtas glomerulosklerozės ir iga indukuotos nefropatijos gydymui

Country Status (16)

Country Link
US (4) US20140142149A1 (lt)
EP (4) EP3222277B1 (lt)
JP (3) JP2012522058A (lt)
CN (2) CN104107176A (lt)
CY (2) CY1119232T1 (lt)
DK (2) DK2732818T3 (lt)
ES (2) ES2636087T3 (lt)
FI (1) FIC20240031I1 (lt)
HK (1) HK1244687A1 (lt)
HR (2) HRP20171197T1 (lt)
HU (2) HUE049450T2 (lt)
LT (2) LT3222277T (lt)
PL (2) PL3222277T3 (lt)
PT (2) PT2732818T (lt)
SI (2) SI3222277T1 (lt)
WO (1) WO2010114801A1 (lt)

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WO2013149258A2 (en) 2012-03-30 2013-10-03 Charles Drew University of Medicine and Science Compositions and methods for treating or preventing metabolic syndrome disorders
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US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
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KR20150132146A (ko) 2013-03-15 2015-11-25 글로벌 블러드 테라퓨틱스, 인크. 헤모글로빈 조정을 위한 화합물 및 이의 용도
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
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CN114404414A (zh) 2013-06-13 2022-04-29 阿克比治疗有限公司 用于治疗贫血症的组合物和方法
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
KR102448369B1 (ko) 2014-02-05 2022-09-28 머크 샤프 앤드 돔 엘엘씨 Cgrp-활성 화합물에 대한 정제 제제
JP6809681B2 (ja) 2014-02-07 2021-01-06 グローバル ブラッド セラピューティクス インコーポレイテッド ２−ヒドロキシ−６−（（２−（１−イソプロピル−１ｈ−ピラゾール−５−イル）ピリジン−３−イル）メトキシ）ベンズアルデヒドの遊離塩基の結晶多形
CN104367576A (zh) * 2014-10-24 2015-02-25 南方医科大学南方医院 化合物icg-001在制备治疗高血压的药物中的用途
CA2995716A1 (en) 2015-08-24 2017-03-02 Trustees Of Boston University Anti-despr monoclonal antibody targeted therapy and imaging for cancer and stroke
TW201731509A (zh) 2015-12-04 2017-09-16 全球血液治療公司 針對２-羥基-６-（（２-（１-異丙基-１ｈ-吡唑-５-基）吡啶-３-基）甲氧基）-苯甲醛之劑量方案
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