HUE032958T2 - 4-Anilino-3-ciano-kinolinok és capecitabin antineoplasztikus kombinációi - Google Patents

4-Anilino-3-ciano-kinolinok és capecitabin antineoplasztikus kombinációi

Info

Publication number
HUE032958T2
HUE032958T2 HUE09791127A HUE09791127A HUE032958T2 HU E032958 T2 HUE032958 T2 HU E032958T2 HU E09791127 A HUE09791127 A HU E09791127A HU E09791127 A HUE09791127 A HU E09791127A HU E032958 T2 HUE032958 T2 HU E032958T2
Authority
HU
Hungary
Prior art keywords
cyanoquinolines
capecitabine
anilino
antineoplastic combinations
antineoplastic
Prior art date
Application number
HUE09791127A
Other languages
English (en)
Hungarian (hu)
Inventor
Kenneth Wang
Charles Zacharchuk
Florence Binlich
Susan Quinn
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41226678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE032958(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of HUE032958T2 publication Critical patent/HUE032958T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE09791127A 2008-08-04 2009-08-04 4-Anilino-3-ciano-kinolinok és capecitabin antineoplasztikus kombinációi HUE032958T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8591308P 2008-08-04 2008-08-04
US17246609P 2009-04-24 2009-04-24

Publications (1)

Publication Number Publication Date
HUE032958T2 true HUE032958T2 (hu) 2017-11-28

Family

ID=41226678

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE09791127A HUE032958T2 (hu) 2008-08-04 2009-08-04 4-Anilino-3-ciano-kinolinok és capecitabin antineoplasztikus kombinációi

Country Status (26)

Country Link
US (2) US8669273B2 (enExample)
EP (3) EP2326329B1 (enExample)
JP (1) JP5681108B2 (enExample)
KR (2) KR101434009B1 (enExample)
CN (6) CN109464445A (enExample)
AU (1) AU2009279771B2 (enExample)
BR (1) BRPI0916694B1 (enExample)
CA (1) CA2730715C (enExample)
CY (1) CY1118602T1 (enExample)
DK (1) DK2326329T3 (enExample)
ES (2) ES2968373T3 (enExample)
HK (1) HK1218262A1 (enExample)
HR (1) HRP20170074T1 (enExample)
HU (1) HUE032958T2 (enExample)
IL (1) IL210616A (enExample)
LT (1) LT2326329T (enExample)
MX (1) MX2011001318A (enExample)
NZ (1) NZ590464A (enExample)
PL (2) PL2326329T3 (enExample)
PT (1) PT2326329T (enExample)
RU (1) RU2498804C2 (enExample)
SG (2) SG10202102855RA (enExample)
SI (1) SI2326329T1 (enExample)
SM (2) SMT201700084T1 (enExample)
WO (1) WO2010017163A1 (enExample)
ZA (1) ZA201101662B (enExample)

Families Citing this family (16)

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PL1848414T3 (pl) 2005-02-03 2011-10-31 Wyeth Llc Sposób leczenia nowotworu opornego na gefitinib
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US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
CA2725598C (en) 2008-06-17 2013-10-08 Wyeth Llc Antineoplastic combinations containing hki-272 and vinorelbine
SMT201700084T1 (it) * 2008-08-04 2017-03-08 Wyeth Llc Associazioni antineoplastiche di 4-anilino-3-cianochinoline e capecitabina
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AU2010315362B2 (en) 2009-11-09 2015-01-22 Wyeth Llc Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea
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CN111110681A (zh) * 2018-10-31 2020-05-08 正大天晴药业集团股份有限公司 喹啉衍生物联合卡培他滨在治疗肝癌的用途
WO2021104319A1 (zh) * 2019-11-25 2021-06-03 正大天晴药业集团股份有限公司 喹唑啉衍生物或其盐的联用药物组合物及其用途

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