HU229095B1 - Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer pharmaceutical compositions containing - Google Patents
Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer pharmaceutical compositions containing Download PDFInfo
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- HU229095B1 HU229095B1 HU0300872A HUP0300872A HU229095B1 HU 229095 B1 HU229095 B1 HU 229095B1 HU 0300872 A HU0300872 A HU 0300872A HU P0300872 A HUP0300872 A HU P0300872A HU 229095 B1 HU229095 B1 HU 229095B1
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- Prior art keywords
- pharmaceutically acceptable
- chlorophenyl
- pharmaceutical composition
- acid
- acid addition
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- Rheumatology (AREA)
- Surgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00202181 | 2000-06-22 | ||
| PCT/EP2001/006747 WO2001098302A1 (en) | 2000-06-22 | 2001-06-13 | Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP0300872A2 HUP0300872A2 (hu) | 2003-07-28 |
| HUP0300872A3 HUP0300872A3 (en) | 2004-11-29 |
| HU229095B1 true HU229095B1 (en) | 2013-07-29 |
Family
ID=8171675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0300872A HU229095B1 (en) | 2000-06-22 | 2001-06-13 | Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer pharmaceutical compositions containing |
Country Status (33)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003018135A1 (en) | 2001-08-24 | 2003-03-06 | Wyeth Holdings Corporation | Method of using 5-(arylsulfonyl)-,5-(arylsulfinyl), and 5-(arylsulfanyl)-thiazolidine-2,4-diones for inhibition of farnesyl-protein transferase |
| AU2003229688B2 (en) | 2002-04-15 | 2009-07-30 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting tricyclic quinazoline derivatives substituted with carbon-linked imidazoles or triazoles |
| US20050003422A1 (en) | 2003-07-01 | 2005-01-06 | Mitch Reponi | Methods for assessing and treating cancer |
| US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| JP2017536403A (ja) * | 2014-12-04 | 2017-12-07 | アイガー・バイオファーマシューティカルズ・インコーポレイテッドＥｉｇｅｒ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | デルタ肝炎ウイルス感染の治療 |
| WO2016172342A1 (en) | 2015-04-21 | 2016-10-27 | Eiger Biopharmaceuticals, Inc. | Pharmaceutical compositions comprising lonafarnib and ritonavir |
| WO2017031101A1 (en) | 2015-08-17 | 2017-02-23 | Kura Oncology, Inc. | Methods of treating cancer patients with farnesyl transferase inhibitors |
| AU2017353838A1 (en) | 2016-11-03 | 2019-05-23 | Kura Oncology, Inc. | Farnesyltransferase inhibitors for use in methods of treating cancer |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1519765A (en) * | 1974-09-05 | 1978-08-02 | Ici Ltd | Pesticidal dihydrotetrazolo(1,5a) quinazolines compositions and processes |
| US4141979A (en) * | 1976-12-23 | 1979-02-27 | Pfizer Inc. | Tetrazolo[a]quinazol-5-ones antiallergy and antiulcer agents |
| GB9513577D0 (en) * | 1995-07-04 | 1995-09-06 | Brotherwood Rodney J | Improvements in passenger carrying vehicles |
| TW349948B (en) * | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
| IL123568A (en) * | 1995-12-08 | 2001-08-08 | Janssen Pharmaceutica Nv | History (Imidazole - 5Il) Methyl-2-quinolinone inhibitors of Prenzyl transferase, their preparation, pharmaceutical preparations containing them and their preparation and drugs containing them |
| AU715658B2 (en) | 1996-04-03 | 2000-02-10 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| TW591030B (en) * | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| KR100520401B1 (ko) * | 1997-04-25 | 2005-10-12 | 얀센 파마슈티카 엔.브이. | 파네실 트랜스퍼라제 억제작용을 갖는 퀴나졸리논 |
| CN1231215C (zh) | 1997-06-02 | 2005-12-14 | 詹森药业有限公司 | (咪唑－5－基)甲基－2－喹啉酮衍生物用作平滑肌细胞增殖抑制剂 |
| HRP20000904A2 (en) | 1998-07-06 | 2001-12-31 | Janssen Pharmaceutica Nv | Farnesyl protein transferase inhibitors for treating arthropathies |
| ATE238811T1 (de) * | 1998-07-06 | 2003-05-15 | Janssen Pharmaceutica Nv | Inhibitoren von farnesylprotein-transferase mit radiosensibilisierenden eigenschaften |
| GEP20033001B (en) * | 1998-08-27 | 2003-06-25 | Pfizer Prod Inc | Alkynyl-Substituted Quinolin-2-One Derivatives Useful As Anticancer Agents |
| JP3494409B2 (ja) * | 1998-08-27 | 2004-02-09 | ファイザー・プロダクツ・インク | 抗がん剤として有用なアルキニル置換キノリン−２−オン誘導体 |
| JP4725940B2 (ja) * | 1998-12-23 | 2011-07-13 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | １，２−環付加キノリン誘導体 |
| US6462201B1 (en) * | 1998-12-29 | 2002-10-08 | Isp Investments Inc. | Process for the production of N-vinyl-2-pyrrolidone by vinylation |
| JP4090200B2 (ja) * | 1999-02-11 | 2008-05-28 | ファイザー・プロダクツ・インク | 抗癌薬として有用なヘテロアリール置換キノリン−２−オン誘導体 |
| HN2000000266A (es) | 2000-01-21 | 2001-05-21 | Pfizer Prod Inc | Compuesto anticanceroso y metodo de separacion de enantiomeros util para sintetizar dicho compuesto. |
| EP1267848B1 (en) * | 2000-02-24 | 2007-10-17 | Janssen Pharmaceutica N.V. | Dosing regimen comprising a farnesyl protein transferase inhibitor for the treatment of cancer |
| US7067531B2 (en) | 2000-09-25 | 2006-06-27 | Angibaud Patrick Rene | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone derivatives |
| US7196094B2 (en) | 2000-09-25 | 2007-03-27 | Janssen Pharmaceutica, N.V. | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives |
-
2001
- 2001-05-29 JO JO200183A patent/JO2361B1/en active
- 2001-06-13 MX MXPA02012845A patent/MXPA02012845A/es active IP Right Grant
- 2001-06-13 IL IL15356001A patent/IL153560A0/xx unknown
- 2001-06-13 AU AU6396201A patent/AU6396201A/xx active Pending
- 2001-06-13 AU AU2001263962A patent/AU2001263962B2/en not_active Expired
- 2001-06-13 EE EEP200200695A patent/EE04966B1/xx unknown
- 2001-06-13 CN CNB018113788A patent/CN1207296C/zh not_active Expired - Lifetime
- 2001-06-13 BR BRPI0111743-2 patent/BRPI0111743B8/pt not_active IP Right Cessation
- 2001-06-13 KR KR1020077026608A patent/KR100846370B1/ko not_active Expired - Lifetime
- 2001-06-13 ES ES01938263T patent/ES2241830T3/es not_active Expired - Lifetime
- 2001-06-13 UA UA20021210152A patent/UA73572C2/uk unknown
- 2001-06-13 HU HU0300872A patent/HU229095B1/hu unknown
- 2001-06-13 KR KR1020027014678A patent/KR100831940B1/ko not_active Expired - Lifetime
- 2001-06-13 HR HR20020989A patent/HRP20020989B1/xx not_active IP Right Cessation
- 2001-06-13 NZ NZ522481A patent/NZ522481A/en not_active IP Right Cessation
- 2001-06-13 AT AT01938263T patent/ATE294804T1/de active
- 2001-06-13 EP EP01938263A patent/EP1296984B1/en not_active Expired - Lifetime
- 2001-06-13 PL PL358918A patent/PL209521B1/pl unknown
- 2001-06-13 CA CA002410232A patent/CA2410232C/en not_active Expired - Lifetime
- 2001-06-13 US US10/312,301 patent/US20030114471A1/en not_active Abandoned
- 2001-06-13 EA EA200300048A patent/EA005065B1/ru not_active IP Right Cessation
- 2001-06-13 SK SK50-2003A patent/SK285699B6/sk not_active IP Right Cessation
- 2001-06-13 DE DE60110592T patent/DE60110592T2/de not_active Expired - Lifetime
- 2001-06-13 CZ CZ2003114A patent/CZ295278B6/cs not_active IP Right Cessation
- 2001-06-13 JP JP2002504258A patent/JP4919575B2/ja not_active Expired - Lifetime
- 2001-06-13 WO PCT/EP2001/006747 patent/WO2001098302A1/en not_active Ceased
- 2001-06-14 PA PA20018519501A patent/PA8519501A1/es unknown
- 2001-06-20 EG EG20010660A patent/EG24180A/xx active
- 2001-06-20 MY MYPI20012896A patent/MY127734A/en unknown
- 2001-06-21 AR ARP010102954A patent/AR030704A1/es not_active Application Discontinuation
- 2001-09-10 SA SA01220349A patent/SA01220349B1/ar unknown
-
2002
- 2002-10-25 IS IS6590A patent/IS2596B/is unknown
- 2002-11-25 BG BG107310A patent/BG65894B1/bg unknown
- 2002-12-16 NO NO20026032A patent/NO324494B1/no not_active IP Right Cessation
- 2002-12-19 IL IL153560A patent/IL153560A/en not_active IP Right Cessation
- 2002-12-19 ZA ZA200210305A patent/ZA200210305B/en unknown
-
2006
- 2006-09-20 AU AU2006220405A patent/AU2006220405B2/en not_active Expired
-
2007
- 2007-01-31 US US11/669,587 patent/US8329714B2/en not_active Expired - Lifetime
- 2007-10-29 US US11/926,741 patent/US8318753B2/en not_active Expired - Lifetime
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