HU228026B1 - Compositions comprising an hiv protease inhibitor and a water soluble vitamin e compound - Google Patents
Compositions comprising an hiv protease inhibitor and a water soluble vitamin e compound Download PDFInfo
- Publication number
- HU228026B1 HU228026B1 HU9901887A HUP9901887A HU228026B1 HU 228026 B1 HU228026 B1 HU 228026B1 HU 9901887 A HU9901887 A HU 9901887A HU P9901887 A HUP9901887 A HU P9901887A HU 228026 B1 HU228026 B1 HU 228026B1
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- Prior art keywords
- water soluble
- pharmaceutical composition
- compound
- weight
- composition according
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1389396P | 1996-03-22 | 1996-03-22 | |
| GBGB9606372.2A GB9606372D0 (en) | 1996-03-26 | 1996-03-26 | Pharmaceutical formulations |
| PCT/EP1997/001438 WO1997035587A1 (en) | 1996-03-22 | 1997-03-21 | Compositions comprising an hiv protease inhibitor such as vx 478 and a water soluble vitamin e compound such as vitamin e-tpgs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP9901887A2 HUP9901887A2 (hu) | 1999-12-28 |
| HUP9901887A3 HUP9901887A3 (en) | 2000-02-28 |
| HU228026B1 true HU228026B1 (en) | 2012-08-28 |
Family
ID=26308992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9901887A HU228026B1 (en) | 1996-03-22 | 1997-03-21 | Compositions comprising an hiv protease inhibitor and a water soluble vitamin e compound |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JP3117726B2 (pl) |
| AR (1) | AR006345A1 (pl) |
| BG (1) | BG64457B1 (pl) |
| CO (1) | CO4790151A1 (pl) |
| HU (1) | HU228026B1 (pl) |
| ID (1) | ID16781A (pl) |
| IL (1) | IL126185A (pl) |
| MY (1) | MY126358A (pl) |
| OA (1) | OA10880A (pl) |
| PL (1) | PL187919B1 (pl) |
| TW (1) | TW455491B (pl) |
| WO (1) | WO1997035587A1 (pl) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998008490A1 (en) * | 1996-09-01 | 1998-03-05 | Pharmos Corporation | Solid coprecipitates for enhanced bioavailability of lipophilic substances |
| AU8145198A (en) * | 1997-06-16 | 1999-01-04 | Vertex Pharmaceuticals Incorporated | Methods of increasing the bioavailability of stable crystal polymorphs of a compound |
| US5891845A (en) * | 1997-11-21 | 1999-04-06 | Fuisz Technologies Ltd. | Drug delivery systems utilizing liquid crystal structures |
| ES2140329B1 (es) * | 1997-12-04 | 2000-10-16 | Univ Granada | Utilizacion de acido maslinico como inhibidor de proteasas para el tratamiento de la enfermedad causada por los virus de la inmunodeficiencia adquirida. |
| GB9812189D0 (en) * | 1998-06-05 | 1998-08-05 | Glaxo Group Ltd | Methods and compositions for increasing penetration of HIV protease inhibitors |
| CA2432527A1 (en) * | 2000-12-22 | 2002-07-04 | Takeda Chemical Industries, Ltd. | Medicinal compositions for oral use |
| WO2004050068A1 (en) * | 2002-11-29 | 2004-06-17 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base |
| US7423004B2 (en) | 2003-01-31 | 2008-09-09 | Smithkline Beecham Corporation | Solid dispersion compositions |
| US20060068007A1 (en) * | 2004-09-24 | 2006-03-30 | Boehringer Ingelheim Pharmaceuticals, Inc. | Class of surfactant-like materials |
| CN101031284A (zh) * | 2004-09-30 | 2007-09-05 | 伊斯曼化学公司 | 使亲脂性药物增溶而无显著外排抑制作用的含有维生素e tpgs分子的药物制剂和该制剂的用途 |
| EP1880715A1 (en) * | 2006-07-19 | 2008-01-23 | Abbott GmbH & Co. KG | Pharmaceutically acceptable solubilizing composition and pharmaceutical dosage form containing same |
| SA109300195B1 (ar) | 2008-03-28 | 2013-04-20 | Astrazeneca Ab | تركيبة صيدلانية جديدة مضادة للسرطان |
| ITRM20120331A1 (it) | 2012-07-12 | 2014-01-13 | Guidotti & C Spa Labor | Composizioni pediatriche orali liquide contenenti nepadutant. |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1677092A (en) * | 1991-03-20 | 1992-10-21 | Vertex Pharmaceuticals Incorporated | Tetrahydroxyalkane derivatives as inhibitors of hiv aspartyl protease |
| ATE163926T1 (de) * | 1991-11-08 | 1998-03-15 | Merck & Co Inc | Hiv-protease-inhibitoren verwendbar in der aids- behandlung |
| IS2334B (is) * | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| AU5748194A (en) * | 1992-12-11 | 1994-07-04 | Vertex Pharmaceuticals Incorporated | Mannitol derivatives and their use as inhibitors of aspartyl protease |
| US5484926A (en) * | 1993-10-07 | 1996-01-16 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors |
| KR100333016B1 (ko) * | 1992-12-29 | 2002-11-22 | 아보트 러보러터리즈 | 레트로바이러스성프로테아제억제화합물,이의제조방법및이를함유하는약제학적조성물 |
| CA2153777A1 (en) * | 1993-01-15 | 1994-07-21 | Siegfried H. Reich | Hiv protease inhibitors |
| WO1995012583A1 (en) * | 1993-11-05 | 1995-05-11 | Merck & Co., Inc. | New quinazolines as inhibitors of hiv reverse transcriptase |
| IL111584A0 (en) * | 1993-11-18 | 1995-01-24 | Merck & Co Inc | Prodrugs of an inhibitor of hiv protease and pharmaceutical compositions containing them |
| AU692509B2 (en) * | 1993-12-15 | 1998-06-11 | Merck & Co., Inc. | HIV protease inhibitors |
| MX9603909A (es) * | 1994-03-07 | 1997-03-29 | Vertex Pharma | Derivados de sulfonamida como inhibidores de proteasa aspartilo. |
| GB9409778D0 (en) * | 1994-05-16 | 1994-07-06 | Dumex Ltd As | Compositions |
| US5527829A (en) * | 1994-05-23 | 1996-06-18 | Agouron Pharmaceuticals, Inc. | HIV protease inhibitors |
| CA2221145A1 (en) * | 1995-05-19 | 1996-11-21 | Abbott Laboratories | Self-emulsifying formulations of lipophilic drugs |
-
1997
- 1997-03-20 MY MYPI97001186A patent/MY126358A/en unknown
- 1997-03-21 WO PCT/EP1997/001438 patent/WO1997035587A1/en active IP Right Grant
- 1997-03-21 AR ARP970101146A patent/AR006345A1/es active IP Right Grant
- 1997-03-21 HU HU9901887A patent/HU228026B1/hu unknown
- 1997-03-21 TW TW086103607A patent/TW455491B/zh not_active IP Right Cessation
- 1997-03-21 PL PL32891697A patent/PL187919B1/pl unknown
- 1997-03-21 CO CO97015457A patent/CO4790151A1/es unknown
- 1997-03-21 IL IL12618597A patent/IL126185A/xx not_active IP Right Cessation
- 1997-03-21 ID IDP970927A patent/ID16781A/id unknown
- 1997-03-21 JP JP09534017A patent/JP3117726B2/ja not_active Expired - Lifetime
-
1998
- 1998-09-18 OA OA9800171A patent/OA10880A/en unknown
- 1998-10-12 BG BG102838A patent/BG64457B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL126185A0 (en) | 1999-05-09 |
| ID16781A (id) | 1997-11-13 |
| PL187919B1 (pl) | 2004-11-30 |
| JP2000500504A (ja) | 2000-01-18 |
| PL328916A1 (en) | 1999-03-01 |
| IL126185A (en) | 2003-05-29 |
| OA10880A (en) | 2001-10-11 |
| WO1997035587A1 (en) | 1997-10-02 |
| JP3117726B2 (ja) | 2000-12-18 |
| BG64457B1 (bg) | 2005-03-31 |
| BG102838A (en) | 1999-09-30 |
| CO4790151A1 (es) | 1999-05-31 |
| TW455491B (en) | 2001-09-21 |
| AR006345A1 (es) | 1999-08-25 |
| MY126358A (en) | 2006-09-29 |
| HUP9901887A2 (hu) | 1999-12-28 |
| HUP9901887A3 (en) | 2000-02-28 |
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