HU216544B - Eljárás 3-helyzetben szubsztituált 2-oxindolok fény hatására történő bomlásának gátlására és a vegyületeket tartalmazó tabletta, kapszula és gyógyszerkészítmény - Google Patents
Eljárás 3-helyzetben szubsztituált 2-oxindolok fény hatására történő bomlásának gátlására és a vegyületeket tartalmazó tabletta, kapszula és gyógyszerkészítmény Download PDFInfo
- Publication number
- HU216544B HU216544B HU9601057A HUP9601057A HU216544B HU 216544 B HU216544 B HU 216544B HU 9601057 A HU9601057 A HU 9601057A HU P9601057 A HUP9601057 A HU P9601057A HU 216544 B HU216544 B HU 216544B
- Authority
- HU
- Hungary
- Prior art keywords
- red
- chlorine
- yellow
- light
- hydrogen
- Prior art date
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- 239000002775 capsule Substances 0.000 title claims description 18
- -1 3-substituted 2-oxindoles Chemical group 0.000 title claims description 17
- 238000000034 method Methods 0.000 title claims description 13
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- 230000002401 inhibitory effect Effects 0.000 title description 4
- 239000000203 mixture Substances 0.000 title description 4
- 238000006303 photolysis reaction Methods 0.000 title description 4
- 239000000460 chlorine Chemical group 0.000 claims abstract description 44
- 229910052801 chlorine Inorganic materials 0.000 claims abstract description 44
- 239000001257 hydrogen Substances 0.000 claims abstract description 30
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 30
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- 239000011737 fluorine Chemical group 0.000 claims abstract description 20
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- 150000001875 compounds Chemical class 0.000 claims description 33
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
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- AJDUTMFFZHIJEM-UHFFFAOYSA-N n-(9,10-dioxoanthracen-1-yl)-4-[4-[[4-[4-[(9,10-dioxoanthracen-1-yl)carbamoyl]phenyl]phenyl]diazenyl]phenyl]benzamide Chemical group O=C1C2=CC=CC=C2C(=O)C2=C1C=CC=C2NC(=O)C(C=C1)=CC=C1C(C=C1)=CC=C1N=NC(C=C1)=CC=C1C(C=C1)=CC=C1C(=O)NC1=CC=CC2=C1C(=O)C1=CC=CC=C1C2=O AJDUTMFFZHIJEM-UHFFFAOYSA-N 0.000 claims description 2
- 239000008177 pharmaceutical agent Substances 0.000 claims 3
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- UYINJAQCJCYCGO-UHFFFAOYSA-N 2-oxo-3h-indole-1-carboxamide Chemical class C1=CC=C2N(C(=O)N)C(=O)CC2=C1 UYINJAQCJCYCGO-UHFFFAOYSA-N 0.000 abstract description 8
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- BDAWXSQJJCIFIK-UHFFFAOYSA-N potassium methoxide Chemical compound [K+].[O-]C BDAWXSQJJCIFIK-UHFFFAOYSA-N 0.000 description 1
- 150000003141 primary amines Chemical class 0.000 description 1
- 239000002599 prostaglandin synthase inhibitor Substances 0.000 description 1
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- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 description 1
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- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4883—Capsule finishing, e.g. dyeing, aromatising, polishing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polymerisation Methods In General (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB1995/000287 WO1996033701A1 (en) | 1995-04-24 | 1995-04-24 | Inhibiting photodecomposition of 3-substituted-2-oxindoles |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| HU9601057D0 HU9601057D0 (en) | 1996-06-28 |
| HUP9601057A2 HUP9601057A2 (en) | 1997-04-28 |
| HUP9601057A3 HUP9601057A3 (en) | 1997-05-28 |
| HU216544B true HU216544B (hu) | 1999-07-28 |
Family
ID=36997502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9601057A HU216544B (hu) | 1995-04-24 | 1996-04-23 | Eljárás 3-helyzetben szubsztituált 2-oxindolok fény hatására történő bomlásának gátlására és a vegyületeket tartalmazó tabletta, kapszula és gyógyszerkészítmény |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0827399A1 (sv) |
| JP (1) | JPH10506635A (sv) |
| KR (1) | KR100189585B1 (sv) |
| CN (1) | CN1053667C (sv) |
| AP (1) | AP607A (sv) |
| AR (1) | AR002728A1 (sv) |
| AU (1) | AU692378B2 (sv) |
| BG (1) | BG100531A (sv) |
| BR (1) | BR9602024A (sv) |
| CO (1) | CO4700418A1 (sv) |
| FI (1) | FI973988A0 (sv) |
| HR (1) | HRP960194A2 (sv) |
| HU (1) | HU216544B (sv) |
| IL (1) | IL117969A0 (sv) |
| IS (1) | IS4339A (sv) |
| MA (1) | MA23848A1 (sv) |
| NO (1) | NO961622L (sv) |
| NZ (1) | NZ286432A (sv) |
| OA (1) | OA10286A (sv) |
| PE (1) | PE34397A1 (sv) |
| RO (1) | RO113305B1 (sv) |
| RU (1) | RU2109510C1 (sv) |
| SG (1) | SG64924A1 (sv) |
| SI (1) | SI9600133A (sv) |
| SK (1) | SK51296A3 (sv) |
| TR (1) | TR199600300A2 (sv) |
| UA (1) | UA42739C2 (sv) |
| WO (1) | WO1996033701A1 (sv) |
| YU (1) | YU25096A (sv) |
| ZA (1) | ZA963210B (sv) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111526730B (zh) | 2017-12-29 | 2024-02-23 | 卡夫食品集团品牌有限责任公司 | 使用天然稳定剂改善的水包油乳液的氧化稳定性 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT59592A (en) * | 1990-07-20 | 1992-06-29 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of solid medical products |
| TW438798B (en) * | 1992-10-07 | 2001-06-07 | Pfizer | 3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions |
-
1995
- 1995-04-24 WO PCT/IB1995/000287 patent/WO1996033701A1/en not_active Application Discontinuation
- 1995-04-24 EP EP95914494A patent/EP0827399A1/en not_active Ceased
- 1995-04-24 RU RU96108120A patent/RU2109510C1/ru active
- 1995-04-24 UA UA96041574A patent/UA42739C2/uk unknown
- 1995-04-24 JP JP8532298A patent/JPH10506635A/ja active Pending
- 1995-04-24 SK SK512-96A patent/SK51296A3/sk unknown
-
1996
- 1996-03-07 AP APAP/P/1996/000787A patent/AP607A/en active
- 1996-03-28 AR ARP960101956A patent/AR002728A1/es unknown
- 1996-04-10 TR TR96/00300A patent/TR199600300A2/xx unknown
- 1996-04-18 IL IL11796996A patent/IL117969A0/xx unknown
- 1996-04-19 SG SG1996009306A patent/SG64924A1/en unknown
- 1996-04-19 IS IS4339A patent/IS4339A/is unknown
- 1996-04-22 PE PE1996000275A patent/PE34397A1/es not_active Application Discontinuation
- 1996-04-22 CN CN96105084A patent/CN1053667C/zh not_active Expired - Fee Related
- 1996-04-22 RO RO96-00843A patent/RO113305B1/ro unknown
- 1996-04-22 CO CO96019210A patent/CO4700418A1/es unknown
- 1996-04-23 NZ NZ286432A patent/NZ286432A/en unknown
- 1996-04-23 KR KR1019960012356A patent/KR100189585B1/ko not_active IP Right Cessation
- 1996-04-23 HR HRPCT/IB95/00287A patent/HRP960194A2/hr not_active Application Discontinuation
- 1996-04-23 HU HU9601057A patent/HU216544B/hu not_active IP Right Cessation
- 1996-04-23 YU YU25096A patent/YU25096A/sh unknown
- 1996-04-23 BG BG100531A patent/BG100531A/xx unknown
- 1996-04-23 NO NO961622A patent/NO961622L/no unknown
- 1996-04-23 AU AU50851/96A patent/AU692378B2/en not_active Ceased
- 1996-04-23 ZA ZA9603210A patent/ZA963210B/xx unknown
- 1996-04-23 MA MA24209A patent/MA23848A1/fr unknown
- 1996-04-24 SI SI9600133A patent/SI9600133A/sl not_active IP Right Cessation
- 1996-04-24 OA OA60821A patent/OA10286A/en unknown
- 1996-04-24 BR BR9602024A patent/BR9602024A/pt active Search and Examination
-
1997
- 1997-10-17 FI FI973988A patent/FI973988A0/sv unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HMM4 | Cancellation of final prot. due to non-payment of fee |