HU216311B - Eljárás sertésterméketlenség- és légzésibetegség-vírus izolálására, tenyésztésére és legyengítésére, valamint az ilyen vírust tartalmazó vakcina előállítására - Google Patents

Eljárás sertésterméketlenség- és légzésibetegség-vírus izolálására, tenyésztésére és legyengítésére, valamint az ilyen vírust tartalmazó vakcina előállítására Download PDF

Info

Publication number
HU216311B
HU216311B HU9202741A HU9202741A HU216311B HU 216311 B HU216311 B HU 216311B HU 9202741 A HU9202741 A HU 9202741A HU 9202741 A HU9202741 A HU 9202741A HU 216311 B HU216311 B HU 216311B
Authority
HU
Hungary
Prior art keywords
virus
sirs
atcc
cell line
culture medium
Prior art date
Application number
HU9202741A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT62323A (en
Inventor
Danny W. Chladek
David E. Gorcyca
Louis L. Harris
Original Assignee
Boehringer Ingelheim Animal Health, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27419390&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU216311(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Animal Health, Inc. filed Critical Boehringer Ingelheim Animal Health, Inc.
Publication of HUT62323A publication Critical patent/HUT62323A/hu
Publication of HU216311B publication Critical patent/HU216311B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10051Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HU9202741A 1991-08-26 1992-08-25 Eljárás sertésterméketlenség- és légzésibetegség-vírus izolálására, tenyésztésére és legyengítésére, valamint az ilyen vírust tartalmazó vakcina előállítására HU216311B (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74983991A 1991-08-26 1991-08-26
US84169292A 1992-02-26 1992-02-26
US92189192A 1992-08-05 1992-08-05

Publications (2)

Publication Number Publication Date
HUT62323A HUT62323A (en) 1993-04-28
HU216311B true HU216311B (hu) 1999-06-28

Family

ID=27419390

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9202741A HU216311B (hu) 1991-08-26 1992-08-25 Eljárás sertésterméketlenség- és légzésibetegség-vírus izolálására, tenyésztésére és legyengítésére, valamint az ilyen vírust tartalmazó vakcina előállítására

Country Status (15)

Country Link
US (1) US5476778A (OSRAM)
EP (1) EP0529584B1 (OSRAM)
JP (2) JP2750557B2 (OSRAM)
KR (1) KR0138092B1 (OSRAM)
AT (1) ATE140238T1 (OSRAM)
CA (1) CA2076744C (OSRAM)
DE (1) DE59206730D1 (OSRAM)
DK (1) DK0529584T3 (OSRAM)
ES (1) ES2089316T3 (OSRAM)
GR (1) GR3020603T3 (OSRAM)
HU (1) HU216311B (OSRAM)
MX (1) MX9204885A (OSRAM)
PL (1) PL169952B1 (OSRAM)
SG (1) SG45288A1 (OSRAM)
TW (1) TW289050B (OSRAM)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103460C (en) 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US5846805A (en) * 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US6080570A (en) * 1991-08-26 2000-06-27 Boehringer Ingelheim Vetmedica, Inc. Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
US6982160B2 (en) * 1991-08-26 2006-01-03 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions that include SIRS virus
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
EP0610250B2 (en) * 1991-10-14 2008-10-29 Intervet International BV Porcine reproductive respiratory syndrome (prrs) vaccine and diagnostic
FR2686097B1 (fr) * 1992-01-14 1994-12-30 Rhone Merieux Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US6251397B1 (en) 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6773908B1 (en) 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
HU218430B (hu) * 1993-02-08 2000-08-28 Bayer Corp. Eljárás sertés reproduktív és légzési szindróma vírus (PRRSV) tenyésztésére és annak alkalmazása vakcinában
DK0676467T3 (da) * 1994-04-11 2002-01-21 Akzo Nobel Nv Europæiske vaccinestammer af det porcine reproduktive respiratoriske syndromvirus (PRRSV)
DK53595A (da) * 1994-05-13 1995-11-14 Iberica Cyanamid Rekombinante PRRSV-proteiner, diagnostiske kits og vaccine indeholdende sådanne rekombinante PRRSV-proteiner
ES2102971B1 (es) * 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US5976537A (en) * 1996-07-02 1999-11-02 The United States Of America As Represented By The Secretary Of Agriculture Porcine reproductive and respiratory syndrome vaccine
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
RU2220978C2 (ru) 1997-05-06 2004-01-10 Стихтинг Динст Ландбаувкюндиг Ондерзук Пептид, индуцирующий образование антител, которые реагируют с двумя различными изолятами вррсс (варианты), иммуногенная композиция, вакцина для профилактики заражения репродуктивно-респираторным синдромом свиней, антитело, диагностический набор (варианты)
CA2290220C (en) 1998-12-22 2013-11-19 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
CA2366072C (en) * 1999-03-08 2007-07-10 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
DK1183332T3 (da) 1999-04-22 2010-09-06 Us Agriculture Porcint Reproduktions- og Respirations Syndrom-vaccine baseret på isolere JA-142
US6841364B2 (en) * 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
US7906311B2 (en) * 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
MXPA06015105A (es) 2004-06-18 2007-03-26 Univ Minnesota Identificacion de organismos viralmente infectados y vacunados.
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
WO2006053061A2 (en) * 2004-11-10 2006-05-18 Kansas State University Research Foundation Porcine reproductive and respiratory syndrome virus receptor components and uses thereof
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
DK2369001T3 (en) 2005-06-24 2016-10-24 Univ Minnesota PRRS viruses, infectious clones, mutants thereof and methods of use
ES2553254T3 (es) 2005-12-29 2015-12-07 Boehringer Ingelheim Vetmedica, Inc. Uso de una composición inmunogénica de PCV2 para reducir los síntomas clínicos en cerdos
CN102698263B (zh) 2005-12-29 2016-07-06 贝林格尔.英格海姆维特梅迪卡有限公司 多价pcv2免疫原性组合物和制备此类组合物的方法
RU2520087C2 (ru) 2006-12-15 2014-06-20 Бёрингер Ингельхайм Ветмедика, Инк. Лечение свиней с помощью антигена pcv2
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
ES2560432T3 (es) * 2007-01-12 2016-02-19 The Board Of Trustees Of The University Of Illinois Células no símicas para el desarrollo del virus del síndrome reproductivo y respiratorio porcino (PRRS)
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
US8563313B2 (en) * 2007-02-13 2013-10-22 Washington State University Research Foundation Macrophage cell-lines for propagation of porcine reproductive and respiratory syndrome virus
US7666585B2 (en) * 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
CN101848995A (zh) * 2007-06-25 2010-09-29 南达科他州立大学 重组的北美1型猪繁殖与呼吸综合征病毒及使用方法
KR101653177B1 (ko) * 2008-08-25 2016-09-01 베링거잉겔하임베트메디카인코퍼레이티드 고병원성 돼지 생식기 및 호흡기 증후군(hp prrs)에 대한 백신
JP5306943B2 (ja) * 2009-08-24 2013-10-02 全国農業協同組合連合会 弱毒ウイルスの作出方法
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
KR200452417Y1 (ko) * 2011-01-21 2011-02-25 임진재 원통형 쿠션 벨트를 이용한 소파 쿠션장치
MY161198A (en) 2011-02-17 2017-04-14 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
KR101983980B1 (ko) 2011-02-17 2019-05-30 베링거잉겔하임베트메디카게엠베하 Prrsv의 상업적 규모의 제조 방법
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
EP2737058A1 (en) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
CA2872789C (en) * 2012-05-17 2019-09-03 Zoetis Llc Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning
WO2014089117A1 (en) 2012-12-07 2014-06-12 The Board Of Trustees Of The University Of Illinois Porcine reproductive and respiratory syndrome virus compositions and uses thereof
WO2014150822A2 (en) 2013-03-15 2014-09-25 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
MX373884B (es) 2013-10-02 2020-03-26 Boehringer Ingelheim Animal Health Usa Inc Variante de la proteína pcv2 orf2 y partículas similares al virus compuestas por ésta.
JP7174698B2 (ja) 2016-11-29 2022-11-17 インターベット インターナショナル ベー. フェー. ブタワクチン
CN110072547B (zh) 2016-12-14 2024-04-30 硕腾服务有限责任公司 断奶前对抗欧洲猪繁殖与呼吸综合征(prrs)病毒株的有效疫苗接种

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2602791B1 (fr) * 1986-08-18 1988-11-10 Ministere Agri Direction Quali Procede de culture du virus de la rhinotracheite infectieuse de la dinde, et vaccin prepare a partir du virus ainsi obtenu

Also Published As

Publication number Publication date
ES2089316T3 (es) 1996-10-01
DE59206730D1 (de) 1996-08-14
JPH08295636A (ja) 1996-11-12
JP2750557B2 (ja) 1998-05-13
KR0138092B1 (ko) 1998-04-30
EP0529584A3 (en) 1993-04-14
EP0529584A2 (de) 1993-03-03
ATE140238T1 (de) 1996-07-15
JPH05276940A (ja) 1993-10-26
TW289050B (OSRAM) 1996-10-21
PL295727A1 (en) 1993-05-17
PL169952B1 (pl) 1996-09-30
KR930004459A (ko) 1993-03-22
MX9204885A (es) 1994-05-31
SG45288A1 (en) 1998-01-16
DK0529584T3 (da) 1996-08-12
GR3020603T3 (en) 1996-10-31
EP0529584B1 (de) 1996-07-10
US5476778A (en) 1995-12-19
HUT62323A (en) 1993-04-28
CA2076744C (en) 2000-06-27
CA2076744A1 (en) 1993-02-27

Similar Documents

Publication Publication Date Title
HU216311B (hu) Eljárás sertésterméketlenség- és légzésibetegség-vírus izolálására, tenyésztésére és legyengítésére, valamint az ilyen vírust tartalmazó vakcina előállítására
US7368117B2 (en) PRRS vaccines
US6241990B1 (en) Immunogenic composition containing inactivated swine infertility and respiratory Syndrome virus
US5683865A (en) Method for diagnosis of mystery swine disease
US5695766A (en) Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US8765142B2 (en) European PRRSV strain
US20150276737A1 (en) Immunogenic compositions including SIRS virus
HK1005014B (en) Sirs vaccine and diagnosis method
US6080570A (en) Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
KR0138068B1 (ko) 미확인(Mystery) 돼지 질병 관련 바이러스제
RU2806601C1 (ru) Штамм "Борз" вируса репродуктивно-респираторного синдрома свиней Betaarterivirus suid 1 рода Arterivirus для изготовления биопрепаратов для специфической профилактики репродуктивно-респираторного синдрома свиней
PL169932B1 (pl) Sposób atenuacji wirusa zespołu niepłodności i oddechowego świń
MXPA97007302A (en) New attenuated cepa of the virus causing the respiratory and reproductive swine syndrome (prrs), vaccines and diagnostic media obtained with the same and the procedures for your obtenc