HU206874B - Process for producing benzopyrane and benzothiopyrane derivatives and pharmaceutical compositions containing them as active component - Google Patents

Process for producing benzopyrane and benzothiopyrane derivatives and pharmaceutical compositions containing them as active component Download PDF

Info

Publication number
HU206874B
HU206874B HU904978A HU497890A HU206874B HU 206874 B HU206874 B HU 206874B HU 904978 A HU904978 A HU 904978A HU 497890 A HU497890 A HU 497890A HU 206874 B HU206874 B HU 206874B
Authority
HU
Hungary
Prior art keywords
alkyl
formula
hydrogen
phenyl
compound
Prior art date
Application number
HU904978A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT54671A (en
HU904978D0 (en
Inventor
James Lawrence Stanton
Yoshitaka Satoh
Alan J Hutchison
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of HU904978D0 publication Critical patent/HU904978D0/hu
Publication of HUT54671A publication Critical patent/HUT54671A/hu
Publication of HU206874B publication Critical patent/HU206874B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
HU904978A 1989-08-11 1990-08-10 Process for producing benzopyrane and benzothiopyrane derivatives and pharmaceutical compositions containing them as active component HU206874B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39251089A 1989-08-11 1989-08-11

Publications (3)

Publication Number Publication Date
HU904978D0 HU904978D0 (en) 1991-01-28
HUT54671A HUT54671A (en) 1991-03-28
HU206874B true HU206874B (en) 1993-01-28

Family

ID=23550888

Family Applications (1)

Application Number Title Priority Date Filing Date
HU904978A HU206874B (en) 1989-08-11 1990-08-10 Process for producing benzopyrane and benzothiopyrane derivatives and pharmaceutical compositions containing them as active component

Country Status (15)

Country Link
EP (1) EP0412939A3 (pt)
JP (1) JPH0383979A (pt)
KR (1) KR910004590A (pt)
AU (1) AU631913B2 (pt)
CA (1) CA2023016A1 (pt)
DD (1) DD297160A5 (pt)
FI (1) FI903928A0 (pt)
HU (1) HU206874B (pt)
IE (1) IE902908A1 (pt)
IL (1) IL95285A0 (pt)
MX (1) MX21917A (pt)
NO (1) NO903533L (pt)
NZ (1) NZ234840A (pt)
PT (1) PT94912A (pt)
ZA (1) ZA906328B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69128477T2 (de) * 1990-07-27 1998-07-16 Chugai Pharmaceutical Co Ltd Benzopyranderivat
FR2673629B1 (fr) * 1991-03-08 1993-05-07 Adir Nouveaux derives du benzopyrane leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4123613C1 (pt) * 1991-07-17 1993-02-04 Gruenenthal Gmbh, 5100 Aachen, De
DE4128690A1 (de) * 1991-08-29 1993-03-04 Boehringer Mannheim Gmbh Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
WO1993020059A1 (en) * 1992-04-07 1993-10-14 Merrell Dow Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2h-1-benzopyrans
FR2691149B1 (fr) * 1992-05-18 1994-07-08 Adir Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5612377A (en) * 1994-08-04 1997-03-18 Minnesota Mining And Manufacturing Company Method of inhibiting leukotriene biosynthesis
DE19647000A1 (de) * 1996-11-14 1998-05-20 Hoechst Ag 3-Amido-chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
US6034256A (en) 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
US6077850A (en) 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
JPH11106381A (ja) * 1997-09-30 1999-04-20 Ss Pharmaceut Co Ltd クロメン誘導体及びその塩並びにこれを含有する医薬
DE69830929T2 (de) * 1997-11-11 2006-04-20 Nikken Chemicals Co., Ltd. N-hydroxyurea-derivat und dieses enthaltende pharmazeutische zusammensetzung
FR2787789B1 (fr) * 1998-12-29 2002-06-14 Lipha Benzopyranes et benzoxepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparations
JP5817614B2 (ja) * 2012-03-26 2015-11-18 日本ゼオン株式会社 ２，５−ジヒドロキシベンズアルデヒド化合物の製造方法
EP2853530A1 (en) * 2013-09-25 2015-04-01 Université de Rennes 1 New PI3K/AKT/mTOR inhibitors and pharmaceutical uses thereof
ES2534336B1 (es) * 2013-10-18 2016-01-28 Artax Biopharma Inc. Derivados de cromeno como inhibidores de la interacción TCR-Nck

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0218373B1 (en) * 1985-09-11 1990-03-07 Beecham Group Plc Chroman derivatives and analogues having antihypertensive activity
FR2593504B1 (fr) * 1986-01-30 1988-12-09 Ile De France Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
GB8830427D0 (en) * 1988-12-30 1989-03-01 Fujisawa Pharmaceutical Co New hydroxylamine derivatives,a process for the preparation thereof and pharmaceutical composition comprising the same
GB8911280D0 (en) * 1989-05-17 1989-07-05 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
NZ234840A (en) 1992-09-25
CA2023016A1 (en) 1991-02-12
HUT54671A (en) 1991-03-28
FI903928A0 (fi) 1990-08-08
AU631913B2 (en) 1992-12-10
IE902908A1 (en) 1991-02-27
EP0412939A2 (en) 1991-02-13
PT94912A (pt) 1991-04-18
MX21917A (es) 1994-02-28
DD297160A5 (de) 1992-01-02
IL95285A0 (en) 1991-06-30
EP0412939A3 (en) 1991-09-04
KR910004590A (ko) 1991-03-29
AU6089590A (en) 1991-02-14
HU904978D0 (en) 1991-01-28
ZA906328B (en) 1991-04-24
JPH0383979A (ja) 1991-04-09
NO903533L (no) 1991-02-12
NO903533D0 (no) 1990-08-10

Similar Documents

Publication Publication Date Title
EP0481676B1 (en) Hydroxyquinolone derivatives
HU206874B (en) Process for producing benzopyrane and benzothiopyrane derivatives and pharmaceutical compositions containing them as active component
EP1092716B1 (fr) Dérivés benzothiophéniques, benzofuraniques et indoliques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
JP3957424B2 (ja) 新規なベンゾチオフェン、ベンゾフランおよびインドール化合物、それらの製造法およびそれらを含む医薬組成物
JPH04338386A (ja) ベンゾジオキソール、ベンゾジオキサンおよびベンゾジオキセピン誘導体
JPH0561273B2 (pt)
JPH07121941B2 (ja) ロイコトリエンｄ▲下４▼拮抗剤としてのキノリニル―ベンゾヘテロ二環式誘導体
JPH07173149A (ja) 中間化合物
JPH0631210B2 (ja) クロマン類及びクロメン類、それらの製法及びそれらを含む医薬組成物
HUT66626A (en) Process for preparing heteroaryl substituted hydroxyamine derivatives and pharmaceutical compositions containing them
JP2003128670A (ja) トロンビンレセプターアンタゴニスト
US5223517A (en) Heterocyclically substituted cycloalkano[b]-indolesulphonamides
US4987138A (en) Active compounds
HU209645B (en) Process for producing heteroaryl-sulphonamido-carbazole derivatives
US4977162A (en) Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments
US5155121A (en) Phenylsulphonamide substituted pyridinealkene- and aminooxyalkanecarboxylic acid derivatives
US5597833A (en) Substituted quinol-2-yl-methoxy-phenylacetic acid derivatives
JPH0678340B2 (ja) 喘息、関節炎および関連疾患の治療におけるアザベンジミダゾール
JPH0673012A (ja) ４−イミノキノリン、その製法およびその使用
JP2620298B2 (ja) １，３‐ジオキサンアルカノイツク酸誘導体、その製法、これを含有する心臓及び血管の疾病の治療剤及び中間体
AU675699B2 (en) New substituted benzodioxins, a process for their preparation and pharmaceutical compositions containing them
KR100497896B1 (ko) 플라본유도체및이를함유하는의약
US5155130A (en) Certain benzopyran and benzothiopyran derivatives
US5310744A (en) Quinolylmethoxyphenyl-acetamides
US5185348A (en) Phenylsulphonamide substituted pyridinealkene- and -aminooxyalkanecarboxylic acid derivatives

Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee