HU201930B - Process for producing azoniaspiro(notropanol) esters and pharmaceutical compositions comprising same - Google Patents
Process for producing azoniaspiro(notropanol) esters and pharmaceutical compositions comprising same Download PDFInfo
- Publication number
- HU201930B HU201930B HU865367A HU536786A HU201930B HU 201930 B HU201930 B HU 201930B HU 865367 A HU865367 A HU 865367A HU 536786 A HU536786 A HU 536786A HU 201930 B HU201930 B HU 201930B
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- radical
- chloride
- general formula
- compound
- Prior art date
Links
- 0 CC(CCC(CCOC(C(*)(*)O)=O)NCC*)CN Chemical compound CC(CCC(CCOC(C(*)(*)O)=O)NCC*)CN 0.000 description 2
- OLRMTSJCFSTLIZ-UHFFFAOYSA-N CC(CCC(C1)N=N)CC1O Chemical compound CC(CCC(C1)N=N)CC1O OLRMTSJCFSTLIZ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853546218 DE3546218A1 (de) | 1985-12-27 | 1985-12-27 | Azoniaspironortropanolester, verfahren zu deren herstellung und pharmazeutisches mittel |
| DE19853546165 DE3546165A1 (de) | 1985-12-27 | 1985-12-27 | Verwendung von azoniaspironortropanolestern als asthmatherapeutikum und als broncholytikum |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT43060A HUT43060A (en) | 1987-09-28 |
| HU201930B true HU201930B (en) | 1991-01-28 |
Family
ID=25839393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU865367A HU201930B (en) | 1985-12-27 | 1986-12-27 | Process for producing azoniaspiro(notropanol) esters and pharmaceutical compositions comprising same |
Country Status (18)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK280875B6 (sk) * | 1994-04-19 | 2000-08-14 | Neurosearch A/S | Tropánové deriváty, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a použitie týchto derivátov na výrobu liečiv |
| US8709476B2 (en) * | 2003-11-04 | 2014-04-29 | Supernus Pharmaceuticals, Inc. | Compositions of quaternary ammonium compounds containing bioavailability enhancers |
| EP1680098A4 (en) * | 2003-11-04 | 2012-06-13 | Supernus Pharmaceuticals Inc | DELAYED RELEASE OF POSITIVELY-LOADED PHARMACOLOGICALLY EFFECTIVE MOLECULES FROM A POLYMER-CONTAINING MATRIX WITH POLARIZED OXYGENATOMES |
| CN101684117B (zh) * | 2008-09-27 | 2013-06-12 | 宁波市医药技术研究有限公司 | 去甲托品醇的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1194422B (de) * | 1963-03-05 | 1965-06-10 | Robert Pfleger Chem Fab Dr | Verfahren zur Herstellung von Azoniaspironortropanderivaten |
| US3480626A (en) * | 1967-05-18 | 1969-11-25 | Chem Fab Dr R Pfleger | Certain azoniaspironortropine derivatives |
| DE1670257A1 (de) * | 1967-08-04 | 1972-03-02 | Boehringer Sohn Ingelheim | Cyclische Aminoverbindungen und Verfahren zu ihrer Herstellung |
| IT1140998B (it) * | 1980-06-18 | 1986-10-10 | Valeas Ind Chimica E Farmaceut | Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo |
-
1986
- 1986-12-19 AT AT0339286A patent/AT397962B/de not_active IP Right Cessation
- 1986-12-22 CH CH5198/86A patent/CH677793A5/de not_active IP Right Cessation
- 1986-12-22 SE SE8605531A patent/SE8605531L/xx not_active Application Discontinuation
- 1986-12-23 FI FI865295A patent/FI865295A7/fi not_active Application Discontinuation
- 1986-12-23 PL PL1986263216A patent/PL150843B1/pl unknown
- 1986-12-23 GB GB8630809A patent/GB2184726B/en not_active Expired - Fee Related
- 1986-12-24 PT PT84022A patent/PT84022B/pt not_active IP Right Cessation
- 1986-12-24 AU AU66985/86A patent/AU584266B2/en not_active Ceased
- 1986-12-24 ES ES8603662A patent/ES2004177A6/es not_active Expired
- 1986-12-24 NL NL8603303A patent/NL193184C/nl not_active IP Right Cessation
- 1986-12-24 IT IT22877/86A patent/IT1198263B/it active
- 1986-12-25 YU YU224986A patent/YU46038B/sh unknown
- 1986-12-26 FR FR8618210A patent/FR2598417B1/fr not_active Expired - Fee Related
- 1986-12-26 SU SU864028726A patent/SU1711674A3/ru active
- 1986-12-27 HU HU865367A patent/HU201930B/hu not_active IP Right Cessation
- 1986-12-27 KR KR1019860011482A patent/KR930000113B1/ko not_active Expired - Fee Related
- 1986-12-29 BE BE2/61142A patent/BE906054A/fr not_active IP Right Cessation
- 1986-12-29 CA CA000526376A patent/CA1304369C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT8622877A0 (it) | 1986-12-24 |
| CA1304369C (en) | 1992-06-30 |
| FR2598417A1 (fr) | 1987-11-13 |
| NL193184C (nl) | 1999-02-02 |
| IT1198263B (it) | 1988-12-21 |
| NL8603303A (nl) | 1987-07-16 |
| YU46038B (sh) | 1992-12-21 |
| IT8622877A1 (it) | 1988-06-24 |
| AT397962B (de) | 1994-08-25 |
| PL263216A1 (en) | 1988-04-14 |
| FI865295L (fi) | 1987-06-28 |
| YU224986A (en) | 1988-04-30 |
| GB2184726A (en) | 1987-07-01 |
| PT84022B (pt) | 1989-07-31 |
| PL150843B1 (en) | 1990-07-31 |
| ES2004177A6 (es) | 1988-12-16 |
| SE8605531D0 (sv) | 1986-12-22 |
| SE8605531L (sv) | 1987-06-28 |
| AU6698586A (en) | 1987-07-02 |
| FI865295A0 (fi) | 1986-12-23 |
| AU584266B2 (en) | 1989-05-18 |
| GB8630809D0 (en) | 1987-02-04 |
| HUT43060A (en) | 1987-09-28 |
| SU1711674A3 (ru) | 1992-02-07 |
| BE906054A (fr) | 1987-06-29 |
| ATA339286A (de) | 1993-12-15 |
| KR870005998A (ko) | 1987-07-08 |
| FI865295A7 (fi) | 1987-06-28 |
| CH677793A5 (enrdf_load_stackoverflow) | 1991-06-28 |
| KR930000113B1 (ko) | 1993-01-09 |
| PT84022A (en) | 1987-01-01 |
| NL193184B (nl) | 1998-10-01 |
| GB2184726B (en) | 1990-10-03 |
| FR2598417B1 (fr) | 1993-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DGB9 | Succession in title of applicant |
Owner name: MADAUS AKTIENGESELLSCHAFT |
|
| HMM4 | Cancellation of final prot. due to non-payment of fee |