HU193556B - Process for preparing benzamide derivatives - Google Patents

Process for preparing benzamide derivatives Download PDF

Info

Publication number
HU193556B
HU193556B HU84767A HU76784A HU193556B HU 193556 B HU193556 B HU 193556B HU 84767 A HU84767 A HU 84767A HU 76784 A HU76784 A HU 76784A HU 193556 B HU193556 B HU 193556B
Authority
HU
Hungary
Prior art keywords
formula
hydrogen
compound
iii
acid
Prior art date
Application number
HU84767A
Other languages
English (en)
Hungarian (hu)
Inventor
Parada Mose Da
Renato Joos
Emilio Kiburz
Pierre C Wyss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HU193556B publication Critical patent/HU193556B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU84767A 1983-03-03 1984-02-27 Process for preparing benzamide derivatives HU193556B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1150/83A CH653670A5 (de) 1983-03-03 1983-03-03 Benzamid-derivate.

Publications (1)

Publication Number Publication Date
HU193556B true HU193556B (en) 1987-10-28

Family

ID=4203649

Family Applications (1)

Application Number Title Priority Date Filing Date
HU84767A HU193556B (en) 1983-03-03 1984-02-27 Process for preparing benzamide derivatives

Country Status (28)

Country Link
JP (1) JPS59167552A (ja)
KR (1) KR910008202B1 (ja)
AR (1) AR243155A1 (ja)
AT (1) AT390948B (ja)
AU (2) AU570431B2 (ja)
BE (1) BE899059A (ja)
CA (1) CA1252794A (ja)
CH (1) CH653670A5 (ja)
DE (1) DE3407654C2 (ja)
DK (1) DK166382C (ja)
ES (3) ES530230A0 (ja)
FI (1) FI79297C (ja)
FR (1) FR2541996B1 (ja)
GB (1) GB2135998B (ja)
GR (1) GR81866B (ja)
HU (1) HU193556B (ja)
IE (1) IE57004B1 (ja)
IL (1) IL71078A (ja)
IT (1) IT1173365B (ja)
LU (1) LU85231A1 (ja)
MC (1) MC1568A1 (ja)
NL (1) NL8400459A (ja)
NO (1) NO165999C (ja)
NZ (1) NZ207272A (ja)
PH (1) PH19623A (ja)
PT (1) PT78187B (ja)
SE (1) SE466447B (ja)
ZA (1) ZA841394B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1261335A (en) * 1984-08-29 1989-09-26 Hoffmann-La Roche Limited/Hoffmann-La Roche Limitee Ethylenediamine monoamide derivatives
US4772630A (en) * 1984-11-23 1988-09-20 Ciba-Geigy Corp. Benzamides and their salts
NZ219974A (en) * 1986-04-22 1989-08-29 Goedecke Ag N-(2'-aminophenyl)-benzamide derivatives, process for their preparation and their use in the control of neoplastic diseases
FR2642972B1 (fr) * 1989-02-14 1994-08-05 Inst Nat Sante Rech Med Agents pour le diagnostic et le traitement des melanomes, derives halogenes aromatiques utilisables comme de tels agents et leur preparation
WO2014155184A1 (en) * 2013-03-28 2014-10-02 Rhenovia Pharma Treatment for parkinson's disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342679A (en) * 1967-09-19 Parts by weight of acid chloride to react with parts of amine in
FR6557M (ja) * 1967-06-20 1968-12-23 Ile De France
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
GB1520584A (en) * 1975-04-02 1978-08-09 Yamanouchi Pharma Co Ltd 2 - alkoxy - 5 substituted benzamide derivatives and their use in pharmaceutical compositions
DE2616486A1 (de) * 1976-04-14 1977-11-03 Basf Ag Farbstoffe der perylentetracarbonsaeurediimidreihe
CA1206964A (en) * 1980-11-12 1986-07-02 Nobuo Shinma Tetra-substituted benzene derivatives
DE3200258A1 (de) * 1982-01-07 1983-07-21 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Substituierte 1-benzoyl-2-phenylimino-imidazolidine, deren saeureadditionssalze, verfahren zu deren herstellung und diese enthaltende arzneimittel
IL69997A0 (en) * 1983-01-03 1984-01-31 Miles Lab Procainamide and n-acetylprocainamide immunogens,antibodies prepared therefrom,labeled conjugates,and the use of such antibodies and labeled conjugates in immunoassays
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides

Also Published As

Publication number Publication date
GB2135998B (en) 1986-09-24
DK147584D0 (da) 1984-02-29
FI79297C (fi) 1989-12-11
GR81866B (ja) 1984-12-12
IT8419778A0 (it) 1984-02-23
PT78187A (en) 1984-04-01
MC1568A1 (fr) 1985-02-04
NO165999B (no) 1991-02-04
JPH0430389B2 (ja) 1992-05-21
KR840009077A (ko) 1984-12-24
SE466447B (sv) 1992-02-17
AU8307987A (en) 1988-06-16
AU570431B2 (en) 1988-03-17
DK166382B (da) 1993-05-10
IL71078A0 (en) 1984-05-31
FR2541996B1 (fr) 1987-12-11
AR243155A1 (es) 1993-07-30
JPS59167552A (ja) 1984-09-21
ATA72484A (de) 1990-01-15
SE8401190L (sv) 1984-09-04
FR2541996A1 (fr) 1984-09-07
NO165999C (no) 1991-05-15
AT390948B (de) 1990-07-25
GB8405486D0 (en) 1984-04-04
AU609758B2 (en) 1991-05-09
IT1173365B (it) 1987-06-24
AU2506684A (en) 1984-09-06
NO840797L (no) 1984-09-04
PH19623A (ja) 1986-06-04
IL71078A (en) 1987-12-31
CA1252794A (en) 1989-04-18
FI840734A0 (fi) 1984-02-22
KR910008202B1 (ko) 1991-10-11
ES8504680A1 (es) 1985-05-01
ES537046A0 (es) 1985-08-16
LU85231A1 (de) 1985-09-12
ES8506600A1 (es) 1985-08-16
PT78187B (en) 1986-08-05
FI79297B (fi) 1989-08-31
ES537045A0 (es) 1985-08-16
DE3407654A1 (de) 1984-09-06
IE840512L (en) 1984-09-03
DK166382C (da) 1993-09-27
NZ207272A (en) 1987-07-31
CH653670A5 (de) 1986-01-15
FI840734A (fi) 1984-09-04
ZA841394B (en) 1985-06-26
ES8506601A1 (es) 1985-08-16
DE3407654C2 (de) 1994-04-07
IE57004B1 (en) 1992-03-11
NL8400459A (nl) 1984-10-01
ES530230A0 (es) 1985-05-01
GB2135998A (en) 1984-09-12
DK147584A (da) 1984-09-04
SE8401190D0 (sv) 1984-03-02
BE899059A (fr) 1984-09-03

Similar Documents

Publication Publication Date Title
JPH09500883A (ja) α１Ａ−アドレナリン受容体アンタゴニストとしてのピペラジン誘導体
PT95231B (pt) Processo de preparacao de inibidores da lipoxigenase contendo indolo,benzofurano e benzotiofeno e de composicoes farmaceuticas
US5872115A (en) 2-ureido-benzamide derivatives
US5382590A (en) N-phenyl-N-acetamidoglycinamides, their preparation and medicaments containing them
US4381398A (en) Amino-alcohol derivatives
HU198014B (en) Process for producing antiarithmic sulfonamides and pharmaceutical compositions containing them
JP2543690B2 (ja) 医薬組成物
US4246267A (en) Aminopiperidines, their production and the pharmaceutical compositions incorporating them
CA2033363A1 (en) Quinazoline derivatives and their preparation
HU193556B (en) Process for preparing benzamide derivatives
US4840967A (en) Carbamate or urea derivatives, their preparation and pharmaceutical compositions comprising them
HU202508B (en) Process for producing new 1,4-disubstituted piperazine derivatives and pharmaceutical compositions containing them as active components
US5238962A (en) Benzamide derivatives
US4780477A (en) Isatin compositions having anti-ulcer activities
US5326785A (en) Caffeic acid derivatives and pharmaceutical compositions containing the same
US4547519A (en) Tetrahydro-3,5-dioxo-1H-pyrrolizine-7a(5H)-carboxylic acid and benzyl esters and amides thereof and their use in reversing amnesia
EP0937054B1 (en) 4-(1-piperazinyl)benzoic acid derivatives, process for preparing them and their therapeutic applications
KR100382998B1 (ko) 6-메톡시-1h-벤조트리아졸-5-카르복사미드유도체,그제조방법및그것을함유하는의약조성물
JPS6317828B2 (ja)
JPH06501701A (ja) 神経保護特性を有するピペリジン誘導体
JPS6315273B2 (ja)
HU184965B (en) Process for producing phenyl-piperazine derivatives of anti-agression activity
PL165125B1 (pl) Sposób wytwarzania nowych zwiazków heterocyklicznych zawierajacych azot i siarke PL PL
LV11546B (en) Pharmacologically active enantiomers
HU182989B (en) Process for producing n-bracket-4-pyrazolidinyl-bracket closed-benzamide derivatives

Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee