HU183013B - Process for producing pharmaceutical compositions containing n-phenyl-n-comma above-bracket-2-imidazolidinilidene-bracket closed-urea derivatives as active agents for treating high blood-pressure and irregular intestinal activity - Google Patents

Process for producing pharmaceutical compositions containing n-phenyl-n-comma above-bracket-2-imidazolidinilidene-bracket closed-urea derivatives as active agents for treating high blood-pressure and irregular intestinal activity Download PDF

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Publication number
HU183013B
HU183013B HU79MA3254A HUMA003254A HU183013B HU 183013 B HU183013 B HU 183013B HU 79MA3254 A HU79MA3254 A HU 79MA3254A HU MA003254 A HUMA003254 A HU MA003254A HU 183013 B HU183013 B HU 183013B
Authority
HU
Hungary
Prior art keywords
formula
phenyl
urea
imidazolidinylidene
active ingredient
Prior art date
Application number
HU79MA3254A
Other languages
English (en)
Hungarian (hu)
Inventor
Chris R Rasmussen
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/972,579 external-priority patent/US4229462A/en
Priority claimed from US05/972,580 external-priority patent/US4239768A/en
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of HU183013B publication Critical patent/HU183013B/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU79MA3254A 1978-12-22 1979-12-21 Process for producing pharmaceutical compositions containing n-phenyl-n-comma above-bracket-2-imidazolidinilidene-bracket closed-urea derivatives as active agents for treating high blood-pressure and irregular intestinal activity HU183013B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/972,579 US4229462A (en) 1978-12-22 1978-12-22 Method for controlling hypertension and compositions
US05/972,580 US4239768A (en) 1978-12-22 1978-12-22 Method for relieving irritable bowel syndrome symptoms

Publications (1)

Publication Number Publication Date
HU183013B true HU183013B (en) 1984-04-28

Family

ID=27130555

Family Applications (1)

Application Number Title Priority Date Filing Date
HU79MA3254A HU183013B (en) 1978-12-22 1979-12-21 Process for producing pharmaceutical compositions containing n-phenyl-n-comma above-bracket-2-imidazolidinilidene-bracket closed-urea derivatives as active agents for treating high blood-pressure and irregular intestinal activity

Country Status (23)

Country Link
AT (1) AT373878B (de)
AU (2) AU532332B2 (de)
CA (1) CA1127651A (de)
CH (1) CH647236A5 (de)
DE (1) DE2951213A1 (de)
DK (1) DK548179A (de)
ES (1) ES487159A0 (de)
FI (1) FI66354C (de)
FR (2) FR2444462B1 (de)
GB (2) GB2040681B (de)
GR (1) GR68018B (de)
HU (1) HU183013B (de)
IL (1) IL59019A (de)
IT (1) IT1126839B (de)
NL (1) NL7909265A (de)
NO (1) NO794249L (de)
NZ (1) NZ192453A (de)
PH (1) PH16571A (de)
PT (1) PT70624A (de)
SE (1) SE7910612L (de)
SU (1) SU971098A3 (de)
YU (1) YU314979A (de)
ZW (1) ZW25379A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673680A (en) * 1985-09-18 1987-06-16 Pendleton Robert G α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
US11516649B2 (en) * 2018-10-29 2022-11-29 Apple Inc. Mechanism to activate and manage a standalone device for cellular service

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1296962A (fr) * 1960-08-05 1962-06-22 Geigy Ag J R Nouveaux composés 2-imino-1.3-di-aza et leur préparation
NL267923A (de) * 1960-08-05

Also Published As

Publication number Publication date
CA1127651A (en) 1982-07-13
CH647236A5 (de) 1985-01-15
IL59019A (en) 1984-05-31
IL59019A0 (en) 1980-03-31
NL7909265A (nl) 1980-06-24
FR2444462B1 (fr) 1986-08-29
FR2445321A1 (de) 1980-07-25
AU5378079A (en) 1980-06-26
AU532332B2 (en) 1983-09-29
FI66354B (fi) 1984-06-29
GB2113204B (en) 1984-02-01
FR2444462A1 (fr) 1980-07-18
IT7951164A0 (it) 1979-12-21
YU314979A (en) 1983-02-28
PT70624A (en) 1980-01-01
AT373878B (de) 1984-02-27
DE2951213A1 (de) 1980-07-10
NO794249L (no) 1980-06-24
PH16571A (en) 1983-11-18
GB2040681A (en) 1980-09-03
ES8101558A1 (es) 1980-12-16
FI66354C (fi) 1984-10-10
AU1640083A (en) 1983-11-17
NZ192453A (en) 1982-09-07
FR2445321B1 (de) 1983-08-26
FI794036A (fi) 1980-06-23
GR68018B (de) 1981-10-27
SU971098A3 (ru) 1982-10-30
SE7910612L (sv) 1980-06-23
GB2113204A (en) 1983-08-03
DK548179A (da) 1980-06-23
GB2040681B (en) 1983-04-13
ZW25379A1 (en) 1981-07-22
ATA808979A (de) 1983-07-15
IT1126839B (it) 1986-05-21
AU566013B2 (en) 1987-10-08
ES487159A0 (es) 1980-12-16

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