HU180567B - Method for producing derivatives of isooxazole - Google Patents

Method for producing derivatives of isooxazole Download PDF

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Publication number
HU180567B
HU180567B HU8080637A HU63780A HU180567B HU 180567 B HU180567 B HU 180567B HU 8080637 A HU8080637 A HU 8080637A HU 63780 A HU63780 A HU 63780A HU 180567 B HU180567 B HU 180567B
Authority
HU
Hungary
Prior art keywords
formula
compound
group
alkyl
defined above
Prior art date
Application number
HU8080637A
Other languages
English (en)
Hungarian (hu)
Inventor
Ferenczik Istvan Pelyvas
Ferenc Sztaricskai
Zoltan Gyoergydeak
Rezsoe Bognar
Jozsef Szegi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU8080637A priority Critical patent/HU180567B/hu
Priority to BE1/10179A priority patent/BE887954A/fr
Priority to SE8101703A priority patent/SE454695B/sv
Priority to YU689/81A priority patent/YU42560B/xx
Priority to ES501095A priority patent/ES8302674A1/es
Priority to DK122581A priority patent/DK151012C/da
Priority to FI810838A priority patent/FI70011C/fi
Priority to FR8105378A priority patent/FR2478634A1/fr
Priority to IT8120395A priority patent/IT1211010B/it
Priority to CH182981A priority patent/CH646157A5/de
Priority to GB8108545A priority patent/GB2075009B/en
Priority to CA000373380A priority patent/CA1163631A/en
Priority to SU813261940A priority patent/SU1053750A3/ru
Priority to DE19813110817 priority patent/DE3110817A1/de
Priority to JP4023281A priority patent/JPS56158774A/ja
Priority to SU823416146A priority patent/SU1158044A3/ru
Priority to SU823414099A priority patent/SU1152518A3/ru
Priority to ES511894A priority patent/ES8401758A1/es
Priority to ES511895A priority patent/ES8305340A1/es
Publication of HU180567B publication Critical patent/HU180567B/hu
Priority to FI852927A priority patent/FI72513C/fi
Priority to FI852926A priority patent/FI72512C/fi
Priority to DK023087A priority patent/DK151959C/da
Priority to DK023187A priority patent/DK153549C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU8080637A 1980-03-19 1980-03-19 Method for producing derivatives of isooxazole HU180567B (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
HU8080637A HU180567B (en) 1980-03-19 1980-03-19 Method for producing derivatives of isooxazole
BE1/10179A BE887954A (fr) 1980-03-19 1981-03-16 Nouveaux derives d'isoxazole, leur procede de preparation et compositions pharmaceutiques les contenant
SE8101703A SE454695B (sv) 1980-03-19 1981-03-17 Nya isoxazolderivat, forfarande for framstellning derav samt farmaceutisk komposition derav
YU689/81A YU42560B (en) 1980-03-19 1981-03-17 Process for obtaining new isoxazole derivatives
ES501095A ES8302674A1 (es) 1980-03-19 1981-03-18 Procedimiento de preparar derivado 5-aminoximetilisoxazolicos.
DK122581A DK151012C (da) 1980-03-19 1981-03-18 Analogifremgangsmaade til fremstilling af 3-methyl-4-halogen-5-aminooxymethyl-isoxazoler eller et syreadditionssalt deraf
FI810838A FI70011C (fi) 1980-03-19 1981-03-18 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-metyl-4-halogen-5-aminooximetyl -isoxazoler
FR8105378A FR2478634A1 (fr) 1980-03-19 1981-03-18 Nouveaux derives d'isoxazole, leur procede de preparation et compositions pharmaceutiques les contenant
IT8120395A IT1211010B (it) 1980-03-19 1981-03-18 Nuovi derivati dell'isossazolo eprocedimento per la loro preparazione.
CH182981A CH646157A5 (en) 1980-03-19 1981-03-18 Isoxazole derivatives and pharmaceutical preparations containing them
GB8108545A GB2075009B (en) 1980-03-19 1981-03-18 Isoxazoles
CA000373380A CA1163631A (en) 1980-03-19 1981-03-19 Isoxazole derivatives and a process for the preparation thereof
SU813261940A SU1053750A3 (ru) 1980-03-19 1981-03-19 Способ получени производных изоксазола
DE19813110817 DE3110817A1 (de) 1980-03-19 1981-03-19 Isoxazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP4023281A JPS56158774A (en) 1980-03-19 1981-03-19 Isoxazole derivative and medicinal composition containing it
SU823416146A SU1158044A3 (ru) 1980-03-19 1982-04-01 Способ получени 3-метил-4-хлор-5-бромэтиламинометилизоксазола или его гидрохлорида
SU823414099A SU1152518A3 (ru) 1980-03-19 1982-04-01 Способ получени производных изоксазола
ES511894A ES8401758A1 (es) 1980-03-19 1982-04-16 "metodo de preparar derivados isoxazol-5-il-metilenoxiguanidinicos".
ES511895A ES8305340A1 (es) 1980-03-19 1982-04-16 "metodo mejorado de obtencion de derivados 5-bromoecilaminometilixoxaxolicos".
FI852927A FI72513C (fi) 1980-03-19 1985-07-26 Foerfarande foer framstaellning av en terapeutiskt anvaendbar 3-metyl-4-klorisoxazol-5-yl-metylenoxiguanidin.
FI852926A FI72512C (fi) 1980-03-19 1985-07-26 Foerfarande foer framstaellning av terapeutiskt anvaendbar 3-metyl-4-klor-5-(brometyl-aminometyl) isoxazol.
DK023087A DK151959C (da) 1980-03-19 1987-01-16 Analogifremgangsmaade til fremstilling af 3-methyl-4-halogenisoxazol-5-yl-methylenoxyguanidin eller farmakologisk acceptable syreadditionssalte deraf
DK023187A DK153549C (da) 1980-03-19 1987-01-16 Analogifremgangsmaade til fremstilling af 3-methyl-4-halogen-5-bromethylaminomethylisoxazoler eller farmakologisk acceptable syreadditionssalte deraf

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU8080637A HU180567B (en) 1980-03-19 1980-03-19 Method for producing derivatives of isooxazole

Publications (1)

Publication Number Publication Date
HU180567B true HU180567B (en) 1983-03-28

Family

ID=10950573

Family Applications (1)

Application Number Title Priority Date Filing Date
HU8080637A HU180567B (en) 1980-03-19 1980-03-19 Method for producing derivatives of isooxazole

Country Status (15)

Country Link
JP (1) JPS56158774A (ja)
BE (1) BE887954A (ja)
CA (1) CA1163631A (ja)
CH (1) CH646157A5 (ja)
DE (1) DE3110817A1 (ja)
DK (3) DK151012C (ja)
ES (3) ES8302674A1 (ja)
FI (1) FI70011C (ja)
FR (1) FR2478634A1 (ja)
GB (1) GB2075009B (ja)
HU (1) HU180567B (ja)
IT (1) IT1211010B (ja)
SE (1) SE454695B (ja)
SU (3) SU1053750A3 (ja)
YU (1) YU42560B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0979226B1 (en) * 1997-04-21 2005-11-09 Sumitomo Pharmaceuticals Company, Limited Isoxazole derivatives
US6100260A (en) * 1997-04-21 2000-08-08 Sumitomo Pharmaceutical Company, Limited Isoxazole derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL302496A (ja) * 1962-12-22
US3808221A (en) * 1971-04-14 1974-04-30 Hoffmann La Roche Antiandrogenic n-(3,5-dilower alkyl-4-heterocyclic)methyl)phthalimides

Also Published As

Publication number Publication date
ES511895A0 (es) 1983-05-01
DK151959C (da) 1988-07-11
DK151959B (da) 1988-01-18
SU1158044A3 (ru) 1985-05-23
DK23187A (da) 1987-01-16
ES501095A0 (es) 1983-02-16
FR2478634B1 (ja) 1983-11-10
DK151012B (da) 1987-10-12
JPS56158774A (en) 1981-12-07
GB2075009A (en) 1981-11-11
SE8101703L (sv) 1981-09-20
YU68981A (en) 1983-10-31
DK153549B (da) 1988-07-25
ES511894A0 (es) 1984-01-01
FI70011B (fi) 1986-01-31
DK151012C (da) 1988-07-04
YU42560B (en) 1988-10-31
DK122581A (da) 1981-09-20
GB2075009B (en) 1983-11-30
FI810838L (fi) 1981-09-20
ES8305340A1 (es) 1983-05-01
SU1053750A3 (ru) 1983-11-07
IT1211010B (it) 1989-09-29
CA1163631A (en) 1984-03-13
FR2478634A1 (fr) 1981-09-25
SE454695B (sv) 1988-05-24
DE3110817A1 (de) 1982-03-04
ES8401758A1 (es) 1984-01-01
DK23087A (da) 1987-01-16
ES8302674A1 (es) 1983-02-16
IT8120395A0 (it) 1981-03-18
DK153549C (da) 1988-12-05
CH646157A5 (en) 1984-11-15
BE887954A (fr) 1981-09-16
FI70011C (fi) 1986-09-12
SU1152518A3 (ru) 1985-04-23

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee
HMM4 Cancellation of final prot. due to non-payment of fee