HU179593B - Process for producing 9-alpha-chloro-11-beta,17-dihydroxy-pregna-1,4-diene-3,20-dione derivatives - Google Patents

Process for producing 9-alpha-chloro-11-beta,17-dihydroxy-pregna-1,4-diene-3,20-dione derivatives

Info

Publication number
HU179593B
HU179593B HU77SCHE624A HUSC000624A HU179593B HU 179593 B HU179593 B HU 179593B HU 77SCHE624 A HU77SCHE624 A HU 77SCHE624A HU SC000624 A HUSC000624 A HU SC000624A HU 179593 B HU179593 B HU 179593B
Authority
HU
Hungary
Prior art keywords
pregna
dihydroxy
diene
chloro
beta
Prior art date
Application number
HU77SCHE624A
Other languages
English (en)
Hungarian (hu)
Inventor
Klaus Annen
Henry Laurent
Rudolf Hofmeistert
Rudolf Wiechert
Hans Wendt
Joachim F Kapp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/de
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of HU179593B publication Critical patent/HU179593B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU77SCHE624A 1976-10-04 1977-10-03 Process for producing 9-alpha-chloro-11-beta,17-dihydroxy-pregna-1,4-diene-3,20-dione derivatives HU179593B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (de) 1976-10-04 1976-10-04 Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat
DE19772742982 DE2742982C2 (de) 1977-09-21 1977-09-21 9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat

Publications (1)

Publication Number Publication Date
HU179593B true HU179593B (en) 1982-11-29

Family

ID=25770978

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77SCHE624A HU179593B (en) 1976-10-04 1977-10-03 Process for producing 9-alpha-chloro-11-beta,17-dihydroxy-pregna-1,4-diene-3,20-dione derivatives

Country Status (21)

Country Link
JP (1) JPS5359654A (nl)
AT (1) AT358202B (nl)
CH (4) CH630098A5 (nl)
DK (1) DK438277A (nl)
ES (1) ES462887A1 (nl)
FI (1) FI58645C (nl)
FR (1) FR2366313A1 (nl)
GB (1) GB1594852A (nl)
GR (1) GR73041B (nl)
HU (1) HU179593B (nl)
IE (1) IE45877B1 (nl)
IL (1) IL53030A (nl)
IT (1) IT1113623B (nl)
LU (1) LU78223A1 (nl)
NL (1) NL7710869A (nl)
NO (1) NO148597C (nl)
NZ (1) NZ185295A (nl)
PL (1) PL110392B1 (nl)
PT (1) PT67109B (nl)
SE (1) SE431655B (nl)
SU (2) SU743581A3 (nl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH0374245A (ja) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd 洗車機
AU2011231543B2 (en) 2010-03-26 2015-01-15 Galderma Research & Development Improved methods and compositions for safe and effective treatment of erythema
US9744168B2 (en) 2011-10-19 2017-08-29 Galderma Laboratories, Inc. Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (zh) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 一种二氟泼尼酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1195748B (de) * 1961-06-24 1965-07-01 Vismara Francesco Spa Verfahren zur Herstellung von 1'-substituierten 17alpha, 21-(1'-Alkoxy)-methylendioxysterioden
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Also Published As

Publication number Publication date
ATA703577A (de) 1980-01-15
FI58645B (fi) 1980-11-28
FI772922A (fi) 1978-04-05
FI58645C (fi) 1981-03-10
NO148597C (no) 1983-11-09
NO773362L (no) 1978-04-05
PT67109A (de) 1977-11-01
GR73041B (nl) 1984-01-26
SE431655B (sv) 1984-02-20
NZ185295A (en) 1980-04-28
CH630098A5 (en) 1982-05-28
PL110392B1 (en) 1980-07-31
SU743581A3 (ru) 1980-06-25
AT358202B (de) 1980-08-25
PT67109B (de) 1979-03-14
IL53030A (en) 1982-11-30
NL7710869A (nl) 1978-04-06
GB1594852A (en) 1981-08-05
IE45877L (en) 1978-04-04
SU751327A3 (ru) 1980-07-23
IE45877B1 (en) 1982-12-15
DK438277A (da) 1978-04-05
PL201161A1 (pl) 1979-01-29
IT1113623B (it) 1986-01-20
FR2366313A1 (fr) 1978-04-28
FR2366313B1 (nl) 1980-02-01
ES462887A1 (es) 1978-12-16
LU78223A1 (nl) 1978-02-01
CH632278A5 (en) 1982-09-30
SE7711039L (sv) 1978-04-05
CH632772A5 (en) 1982-10-29
CH631997A5 (en) 1982-09-15
JPS6129960B2 (nl) 1986-07-10
NO148597B (no) 1983-08-01
IL53030A0 (en) 1977-11-30
JPS5359654A (en) 1978-05-29

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