HU177601B - New process for preparing 6-piperidino-2,4-diamino-pyrimidine-3-oxide - Google Patents

New process for preparing 6-piperidino-2,4-diamino-pyrimidine-3-oxide Download PDF

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Publication number
HU177601B
HU177601B HU78EE2594A HUEE002594A HU177601B HU 177601 B HU177601 B HU 177601B HU 78EE2594 A HU78EE2594 A HU 78EE2594A HU EE002594 A HUEE002594 A HU EE002594A HU 177601 B HU177601 B HU 177601B
Authority
HU
Hungary
Prior art keywords
formula
diaminopyrimidine
defined above
priority
piperidine
Prior art date
Application number
HU78EE2594A
Other languages
English (en)
Hungarian (hu)
Inventor
Andras Vedres
Csaba Szantay
Gyula Balogh
Judith Horvath
Tamas Mester
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU78EE2594A priority Critical patent/HU177601B/hu
Priority to SE7908629A priority patent/SE432596B/sv
Priority to AT0689879A priority patent/AT373246B/de
Priority to GB7936681A priority patent/GB2032434B/en
Priority to FI793307A priority patent/FI793307A/fi
Priority to CS797272A priority patent/CS213398B2/cs
Priority to CH958279A priority patent/CH642365A5/de
Priority to DE19792943161 priority patent/DE2943161A1/de
Priority to SU792830754A priority patent/SU913942A3/ru
Priority to DK454579A priority patent/DK454579A/da
Priority to PL1979219242A priority patent/PL119712B1/pl
Priority to YU02625/79A priority patent/YU262579A/xx
Priority to ES485457A priority patent/ES485457A1/es
Priority to JP13829279A priority patent/JPS5559172A/ja
Publication of HU177601B publication Critical patent/HU177601B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU78EE2594A 1978-10-27 1978-10-27 New process for preparing 6-piperidino-2,4-diamino-pyrimidine-3-oxide HU177601B (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
HU78EE2594A HU177601B (en) 1978-10-27 1978-10-27 New process for preparing 6-piperidino-2,4-diamino-pyrimidine-3-oxide
SE7908629A SE432596B (sv) 1978-10-27 1979-10-17 Forfarande for framstellning av 6-piperidino-2,4-diaminopyrimidin-3-oxid
AT0689879A AT373246B (de) 1978-10-27 1979-10-23 Neues verfahren zur herstellung von 6-piperidino- 2,4-diaminopyrimidin-3-oxid
GB7936681A GB2032434B (en) 1978-10-27 1979-10-23 Process for the preparation of 6 - piperidino - 2,4 - diamino - pyrimidine - 3-oxide
FI793307A FI793307A (fi) 1978-10-27 1979-10-24 Foerfarande foer framstaellning av 6-piperidino-2,4-diaminopyrimidin-3-oxid
CS797272A CS213398B2 (en) 1978-10-27 1979-10-25 Method of making the 6-piperidino-2,4-diaminopyrimidin-3-oxide
CH958279A CH642365A5 (de) 1978-10-27 1979-10-25 Verfahren zur herstellung von 6-piperidino-2,4-diaminopyrimidin-3-oxid.
DE19792943161 DE2943161A1 (de) 1978-10-27 1979-10-25 Verfahren zur herstellung von 6-piperidino-2,4-diaminopyrimidin-3- oxyd
SU792830754A SU913942A3 (en) 1978-10-27 1979-10-25 Process for producing 2,4-diamino-6-pyperidinopyrimidine-3-oxy (its modifications)
DK454579A DK454579A (da) 1978-10-27 1979-10-26 Fremgangsmaade til fremstilling af 6-piperidino-2,4-diaminopyrimidin-3-oxid
PL1979219242A PL119712B1 (en) 1978-10-27 1979-10-26 Process for preparing 6-piperidin-2,4-diaminopyrimidine 3-oxideina
YU02625/79A YU262579A (en) 1978-10-27 1979-10-26 New process for obtaining 6-piperidino-2,4-diamino-pyrimidine-3-oxide
ES485457A ES485457A1 (es) 1978-10-27 1979-10-26 Procedimiento de preparacion de 6-piperidino-2,4-diaminopi- rimidina-3-oxido
JP13829279A JPS5559172A (en) 1978-10-27 1979-10-27 Manufacture of 66piperidinoo2*44diaminopyrimidinee33oxide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU78EE2594A HU177601B (en) 1978-10-27 1978-10-27 New process for preparing 6-piperidino-2,4-diamino-pyrimidine-3-oxide

Publications (1)

Publication Number Publication Date
HU177601B true HU177601B (en) 1981-11-28

Family

ID=10995794

Family Applications (1)

Application Number Title Priority Date Filing Date
HU78EE2594A HU177601B (en) 1978-10-27 1978-10-27 New process for preparing 6-piperidino-2,4-diamino-pyrimidine-3-oxide

Country Status (14)

Country Link
JP (1) JPS5559172A (sv)
AT (1) AT373246B (sv)
CH (1) CH642365A5 (sv)
CS (1) CS213398B2 (sv)
DE (1) DE2943161A1 (sv)
DK (1) DK454579A (sv)
ES (1) ES485457A1 (sv)
FI (1) FI793307A (sv)
GB (1) GB2032434B (sv)
HU (1) HU177601B (sv)
PL (1) PL119712B1 (sv)
SE (1) SE432596B (sv)
SU (1) SU913942A3 (sv)
YU (1) YU262579A (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1179344A (en) * 1981-07-15 1984-12-11 Jean-Claude Muller Process for the preparation of 6-¬3,6-dihydro-1(2h)- pyridyl| pyrimidine-3-oxides
CH649291A5 (de) * 1982-03-16 1985-05-15 Hoffmann La Roche Dicarbamate.
HU196061B (en) * 1986-07-10 1988-09-28 Richter Gedeon Vegyeszet Process for production of pirimidine-derivatives
HU196067B (en) * 1986-07-10 1988-09-28 Richter Gedeon Vegyeszet Process for production of 6-amin-1,2-dihydro-1-hydroxi-2-imino-4-piperidin-piramidin
FI864046A (fi) * 1986-10-07 1988-04-08 Farmos Oy Foerfarande foer framstaellning av en terapeutiskt aktiv foerening.
LU86958A1 (fr) * 1987-07-31 1989-03-08 Oreal Sels d'acide thiamorpholinone carboxylique et de derives de diamino-2,4 pyrimidine,leur utilisation en cosmetique et pharmacie
LU86960A1 (fr) * 1987-07-31 1989-03-08 Oreal Procede de preparation de piperidino-6 diamino-2,4 pyrimidine oxyde-3 et composes nouveaux
US4959475A (en) * 1989-01-04 1990-09-25 Lonza Ltd. Process for the production of 2,4-diamino-6-piperidinyl-pyrimidine-3-N-oxide

Also Published As

Publication number Publication date
CS213398B2 (en) 1982-04-09
DE2943161A1 (de) 1980-05-08
YU262579A (en) 1983-01-21
SU913942A3 (en) 1982-03-15
DK454579A (da) 1980-04-28
SE432596B (sv) 1984-04-09
FI793307A (fi) 1980-04-28
CH642365A5 (de) 1984-04-13
PL219242A1 (sv) 1980-06-16
PL119712B1 (en) 1982-01-30
ATA689879A (de) 1983-05-15
GB2032434A (en) 1980-05-08
JPS5559172A (en) 1980-05-02
SE7908629L (sv) 1980-04-28
GB2032434B (en) 1982-11-17
ES485457A1 (es) 1980-10-01
AT373246B (de) 1983-12-27

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee