HU172684B - Process for producing new piperazinyl-pirazine derivatives of anorexic activitysposob poluchenija novykh proizvodnykh piperazinil-pirazina s anoreksionnojj aktivnost'ju - Google Patents

Process for producing new piperazinyl-pirazine derivatives of anorexic activitysposob poluchenija novykh proizvodnykh piperazinil-pirazina s anoreksionnojj aktivnost'ju

Info

Publication number
HU172684B
HU172684B HU76ME00001967A HUME001967A HU172684B HU 172684 B HU172684 B HU 172684B HU 76ME00001967 A HU76ME00001967 A HU 76ME00001967A HU ME001967 A HUME001967 A HU ME001967A HU 172684 B HU172684 B HU 172684B
Authority
HU
Hungary
Prior art keywords
proizvodnykh
poluchenia
novykh
anorexion
activitysposob
Prior art date
Application number
HU76ME00001967A
Other languages
English (en)
Hungarian (hu)
Inventor
Walfred S Saari
Jun William C Lumma
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HU172684B publication Critical patent/HU172684B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU76ME00001967A 1975-04-21 1976-04-21 Process for producing new piperazinyl-pirazine derivatives of anorexic activitysposob poluchenija novykh proizvodnykh piperazinil-pirazina s anoreksionnojj aktivnost'ju HU172684B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57005275A 1975-04-21 1975-04-21

Publications (1)

Publication Number Publication Date
HU172684B true HU172684B (hu) 1978-11-28

Family

ID=24277994

Family Applications (1)

Application Number Title Priority Date Filing Date
HU76ME00001967A HU172684B (hu) 1975-04-21 1976-04-21 Process for producing new piperazinyl-pirazine derivatives of anorexic activitysposob poluchenija novykh proizvodnykh piperazinil-pirazina s anoreksionnojj aktivnost'ju

Country Status (36)

Country Link
JP (1) JPS51136688A (enExample)
AR (1) AR210349A1 (enExample)
AT (1) AT353795B (enExample)
AU (1) AU496854B2 (enExample)
BE (1) BE840904A (enExample)
BG (1) BG34185A3 (enExample)
CA (1) CA1059128A (enExample)
CH (1) CH619462A5 (enExample)
CS (1) CS195726B2 (enExample)
CY (1) CY1090A (enExample)
DD (1) DD124599A5 (enExample)
DE (1) DE2617205C3 (enExample)
DK (1) DK143899C (enExample)
EG (1) EG12387A (enExample)
ES (4) ES447150A1 (enExample)
FI (1) FI62666C (enExample)
FR (1) FR2308367A1 (enExample)
GB (1) GB1492528A (enExample)
GR (1) GR59900B (enExample)
HK (1) HK60380A (enExample)
HU (1) HU172684B (enExample)
IE (1) IE42979B1 (enExample)
IL (1) IL49391A (enExample)
KE (1) KE3088A (enExample)
LU (1) LU74795A1 (enExample)
MY (1) MY8100225A (enExample)
NL (1) NL167692C (enExample)
NO (1) NO146599C (enExample)
PH (1) PH12274A (enExample)
PL (1) PL99664B1 (enExample)
PT (1) PT65027B (enExample)
RO (1) RO73278A (enExample)
SE (1) SE421695B (enExample)
SU (1) SU638260A3 (enExample)
YU (1) YU100676A (enExample)
ZA (1) ZA762320B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4163849A (en) 1978-03-17 1979-08-07 Merck & Co., Inc. Piperazinylpyrazines
US4252816A (en) * 1979-12-03 1981-02-24 Merck & Co., Inc. Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents
US4339579A (en) 1980-12-29 1982-07-13 American Home Products Corporation 2,6-Bis-(pyrrolopyrazinyl)pyrazines
EP0094498A3 (en) * 1982-05-06 1985-04-03 American Cyanamid Company Antiatherosclerotic 1-piperazine derivatives
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US4788290A (en) * 1987-12-11 1988-11-29 American Home Products Corporation Serotonergic pyrazine derivatives
EP0580465A1 (fr) * 1992-06-25 1994-01-26 Sanofi Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés
KR100607838B1 (ko) 1997-10-27 2006-08-04 뉴로서치 에이/에스 니코틴 작용성 아세틸콜린 수용체상의 콜린 작용성 리간드로서의 호모피페라진 유도체 및 이를 포함하는 약제학적 조성물
EP1175416B1 (en) 1999-04-26 2003-07-16 Neurosearch A/S Heteroaryl diazacycloalkanes, their preparation and use
ATE307121T1 (de) * 2000-02-16 2005-11-15 Neurogen Corp Substituierte arylpyrazine
US6825198B2 (en) * 2001-06-21 2004-11-30 Pfizer Inc 5-HT receptor ligands and uses thereof
DK1534391T3 (da) 2002-07-19 2007-06-11 Biovitrum Ab Nye piperazinyl-pyrazinonderivater til behandling af 5-HT2A-recptor-relaterede forstyrrelser
SE0202287D0 (sv) * 2002-07-19 2002-07-19 Biovitrum Ab New compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2606906A (en) * 1948-10-14 1952-08-12 American Cyanamid Co 1-(2-pyridyl) piperazine and process of preparing same

Also Published As

Publication number Publication date
NO146599B (no) 1982-07-26
CS195726B2 (en) 1980-02-29
DE2617205B2 (de) 1980-05-08
DD124599A5 (enExample) 1977-03-02
FR2308367B1 (enExample) 1979-09-21
ZA762320B (en) 1977-11-30
NL167692B (nl) 1981-08-17
SE421695B (sv) 1982-01-25
MY8100225A (en) 1981-12-31
ES459406A1 (es) 1978-08-16
YU100676A (en) 1982-08-31
BE840904A (fr) 1976-08-16
JPS51136688A (en) 1976-11-26
RO73278A (ro) 1982-09-09
AT353795B (de) 1979-12-10
AU496854B2 (en) 1978-11-02
LU74795A1 (enExample) 1977-02-07
SU638260A3 (ru) 1978-12-15
ES459405A1 (es) 1978-08-16
SE7604093L (sv) 1976-10-22
NO761207L (enExample) 1976-10-22
AU1296676A (en) 1977-10-20
ATA288376A (de) 1979-05-15
FR2308367A1 (fr) 1976-11-19
ES447150A1 (es) 1977-09-16
FI62666C (fi) 1983-02-10
PH12274A (en) 1978-12-12
NL167692C (nl) 1982-01-18
CA1059128A (en) 1979-07-24
PT65027A (en) 1976-05-01
DE2617205C3 (de) 1981-01-29
DE2617205A1 (de) 1976-10-28
NO146599C (no) 1982-11-03
BG34185A3 (bg) 1983-07-15
JPS5522475B2 (enExample) 1980-06-17
IL49391A (en) 1979-09-30
PL99664B1 (pl) 1978-07-31
NL7603800A (nl) 1976-10-25
DK143899B (da) 1981-10-26
IE42979L (en) 1976-10-21
GR59900B (en) 1978-03-16
FI760978A7 (enExample) 1976-10-22
EG12387A (en) 1978-12-31
CY1090A (en) 1980-12-27
HK60380A (en) 1980-11-07
IL49391A0 (en) 1976-06-30
DK164476A (da) 1976-10-22
FI62666B (fi) 1982-10-29
KE3088A (en) 1980-11-07
AR210349A1 (es) 1977-07-29
CH619462A5 (en) 1980-09-30
IE42979B1 (en) 1980-11-19
DK143899C (da) 1982-04-13
GB1492528A (en) 1977-11-23
ES459407A1 (es) 1978-08-16
PT65027B (en) 1978-04-03

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