RO71908A - Procedeu pentru prepararea unor esteri ai acidului 7 beta-acilamino-3-clor-3-cefem-4-carboxilic - Google Patents
Procedeu pentru prepararea unor esteri ai acidului 7 beta-acilamino-3-clor-3-cefem-4-carboxilicInfo
- Publication number
- RO71908A RO71908A RO7791365A RO9136577A RO71908A RO 71908 A RO71908 A RO 71908A RO 7791365 A RO7791365 A RO 7791365A RO 9136577 A RO9136577 A RO 9136577A RO 71908 A RO71908 A RO 71908A
- Authority
- RO
- Romania
- Prior art keywords
- acid
- cefem
- acylamino
- chloro
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71494876A | 1976-08-16 | 1976-08-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RO71908A true RO71908A (ro) | 1981-11-24 |
Family
ID=24872131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO7791365A RO71908A (ro) | 1976-08-16 | 1977-08-15 | Procedeu pentru prepararea unor esteri ai acidului 7 beta-acilamino-3-clor-3-cefem-4-carboxilic |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4115643A (ro) |
| JP (1) | JPS5323994A (ro) |
| BE (1) | BE857244A (ro) |
| BG (1) | BG28068A3 (ro) |
| CA (1) | CA1099256A (ro) |
| CH (1) | CH630924A5 (ro) |
| CS (1) | CS192588B2 (ro) |
| DD (1) | DD131858A5 (ro) |
| DE (1) | DE2735454A1 (ro) |
| ES (1) | ES461587A1 (ro) |
| FI (1) | FI66873C (ro) |
| FR (1) | FR2362145A1 (ro) |
| GB (1) | GB1582044A (ro) |
| HU (1) | HU179459B (ro) |
| IE (1) | IE45158B1 (ro) |
| IL (1) | IL52416A (ro) |
| NL (1) | NL7709055A (ro) |
| PL (1) | PL110242B1 (ro) |
| RO (1) | RO71908A (ro) |
| SU (1) | SU1018586A3 (ro) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT342197B (de) * | 1975-02-20 | 1978-03-28 | Ciba Geigy Ag | Neues verfahren zur herstellung von 3-cephemverbindungen |
| US4223133A (en) * | 1979-02-01 | 1980-09-16 | Eli Lilly And Company | Cephalosporin reduction process |
| US4271305A (en) * | 1979-02-01 | 1981-06-02 | Eli Lilly And Company | Thiazolinoazetidinones and process therefor |
| US4226986A (en) * | 1979-02-01 | 1980-10-07 | Eli Lilly And Company | Process for halogenation of β-lactam compounds |
| US4237279A (en) * | 1979-07-27 | 1980-12-02 | Eli Lilly And Company | Crystalline 3-hydroxycephalosporin solvates |
| US4281117A (en) * | 1980-09-04 | 1981-07-28 | Eli Lilly And Company | Process for 3-chloro cephalosporin nucleus |
| US5159071A (en) * | 1990-09-06 | 1992-10-27 | Ranbaxy Laboratories Limited | Process for the manufacture of 7-amino-3-exomethylene-3-cepham-4-carboxylic acid ester |
| US5350845A (en) * | 1992-04-08 | 1994-09-27 | Eli Lilly And Company | Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters |
| IN181695B (ro) * | 1992-08-10 | 1998-09-05 | Ranbaxy Lab Ltd | |
| US5604222A (en) * | 1993-12-27 | 1997-02-18 | Lupin Laboratories, Ltd. | Method for the preparation of 2-chloro sulfinyl azetidinones |
| US5578721A (en) * | 1994-07-11 | 1996-11-26 | Lupin Laboratories Limited | Process for preparation of 3-exomethylene cepham sulfoxide esters |
| KR100390551B1 (ko) * | 1996-08-22 | 2003-11-17 | 주식회사 코오롱 | 3-할로메틸-3-세펨-4-카르복실레이트 1-옥사이드의 제조방법 |
| CN101190921B (zh) * | 2007-11-27 | 2010-05-19 | 吉林省石油化工设计研究院 | 一种对硝基苄基-7-苯氧基乙酰胺-3-外亚甲基头孢-4-羧酸酯-1-β-氧化物制备方法 |
| CN102443014B (zh) * | 2011-12-29 | 2014-07-09 | 上海右手医药科技开发有限公司 | 3-氯头孢菌素衍生物及其合成方法与在头孢克洛制备中的应用 |
| CN103588790A (zh) * | 2013-11-29 | 2014-02-19 | 中国科学院长春应用化学研究所 | 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3641014A (en) * | 1968-10-03 | 1972-02-08 | Lilly Co Eli | Reduction of delta**3-cephalosporin sulfoxides |
| AR208068A1 (es) * | 1973-02-23 | 1976-11-30 | Lilly Co Eli | Un procedimiento para preparar derivados de acidos 7-acilamido-3-halo-cefem-4-carboxilico los esteres y las sales farmaceuticamente aceptables de los mismos |
| US3925372A (en) * | 1973-02-23 | 1975-12-09 | Lilly Co Eli | Alpha-aminoacyl-3-halo cephalosporins |
| US3962227A (en) * | 1973-02-23 | 1976-06-08 | Eli Lilly And Company | 3-halo cephalosporins |
| YU36970B (en) * | 1973-02-23 | 1984-08-31 | Lilly Co Eli | Process for obtaining 7-(amino)-acylamido-3-halocephalosporins |
-
1977
- 1977-06-28 IE IE1320/77A patent/IE45158B1/en not_active IP Right Cessation
- 1977-06-29 IL IL52416A patent/IL52416A/xx unknown
- 1977-07-18 CA CA282,954A patent/CA1099256A/en not_active Expired
- 1977-07-22 BG BG7736981A patent/BG28068A3/xx unknown
- 1977-07-28 BE BE1008305A patent/BE857244A/xx not_active IP Right Cessation
- 1977-07-28 FR FR7723211A patent/FR2362145A1/fr active Granted
- 1977-08-01 FI FI772339A patent/FI66873C/fi not_active IP Right Cessation
- 1977-08-05 DE DE19772735454 patent/DE2735454A1/de active Granted
- 1977-08-08 US US05/822,472 patent/US4115643A/en not_active Expired - Lifetime
- 1977-08-09 CH CH977177A patent/CH630924A5/de not_active IP Right Cessation
- 1977-08-10 GB GB33451/77A patent/GB1582044A/en not_active Expired
- 1977-08-12 ES ES461587A patent/ES461587A1/es not_active Expired
- 1977-08-15 SU SU772511154A patent/SU1018586A3/ru active
- 1977-08-15 PL PL1977200289A patent/PL110242B1/pl not_active IP Right Cessation
- 1977-08-15 HU HU77EI758A patent/HU179459B/hu unknown
- 1977-08-15 RO RO7791365A patent/RO71908A/ro unknown
- 1977-08-16 JP JP9817777A patent/JPS5323994A/ja active Granted
- 1977-08-16 NL NL7709055A patent/NL7709055A/xx not_active Application Discontinuation
- 1977-08-16 DD DD7700200594A patent/DD131858A5/xx unknown
- 1977-08-16 CS CS775383A patent/CS192588B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES461587A1 (es) | 1978-06-01 |
| PL200289A1 (pl) | 1978-05-08 |
| CH630924A5 (de) | 1982-07-15 |
| NL7709055A (nl) | 1978-02-20 |
| SU1018586A3 (ru) | 1983-05-15 |
| JPS5323994A (en) | 1978-03-06 |
| JPS6120556B2 (ro) | 1986-05-22 |
| CA1099256A (en) | 1981-04-14 |
| GB1582044A (en) | 1980-12-31 |
| FI66873C (fi) | 1984-12-10 |
| FI772339A (fi) | 1978-02-17 |
| US4115643A (en) | 1978-09-19 |
| FR2362145B1 (ro) | 1980-02-15 |
| IL52416A (en) | 1980-02-29 |
| PL110242B1 (en) | 1980-07-31 |
| BE857244A (fr) | 1978-01-30 |
| IE45158L (en) | 1978-02-16 |
| BG28068A3 (en) | 1980-02-25 |
| DE2735454C2 (ro) | 1992-12-10 |
| IE45158B1 (en) | 1982-06-30 |
| FR2362145A1 (fr) | 1978-03-17 |
| HU179459B (en) | 1982-10-28 |
| CS192588B2 (en) | 1979-08-31 |
| FI66873B (fi) | 1984-08-31 |
| IL52416A0 (en) | 1977-08-31 |
| DE2735454A1 (de) | 1978-02-23 |
| DD131858A5 (de) | 1978-07-26 |
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