BE857244A - Procede de preparation de 3-chlorocephalosporines - Google Patents

Procede de preparation de 3-chlorocephalosporines

Info

Publication number
BE857244A
BE857244A BE1008305A BE1008305A BE857244A BE 857244 A BE857244 A BE 857244A BE 1008305 A BE1008305 A BE 1008305A BE 1008305 A BE1008305 A BE 1008305A BE 857244 A BE857244 A BE 857244A
Authority
BE
Belgium
Prior art keywords
chlorocephalosporins
preparation
Prior art date
Application number
BE1008305A
Other languages
English (en)
French (fr)
Inventor
S Kukolja
D O Spry
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE857244A publication Critical patent/BE857244A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
BE1008305A 1976-08-16 1977-07-28 Procede de preparation de 3-chlorocephalosporines BE857244A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71494876A 1976-08-16 1976-08-16

Publications (1)

Publication Number Publication Date
BE857244A true BE857244A (fr) 1978-01-30

Family

ID=24872131

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1008305A BE857244A (fr) 1976-08-16 1977-07-28 Procede de preparation de 3-chlorocephalosporines

Country Status (20)

Country Link
US (1) US4115643A (ro)
JP (1) JPS5323994A (ro)
BE (1) BE857244A (ro)
BG (1) BG28068A3 (ro)
CA (1) CA1099256A (ro)
CH (1) CH630924A5 (ro)
CS (1) CS192588B2 (ro)
DD (1) DD131858A5 (ro)
DE (1) DE2735454A1 (ro)
ES (1) ES461587A1 (ro)
FI (1) FI66873C (ro)
FR (1) FR2362145A1 (ro)
GB (1) GB1582044A (ro)
HU (1) HU179459B (ro)
IE (1) IE45158B1 (ro)
IL (1) IL52416A (ro)
NL (1) NL7709055A (ro)
PL (1) PL110242B1 (ro)
RO (1) RO71908A (ro)
SU (1) SU1018586A3 (ro)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4271305A (en) * 1979-02-01 1981-06-02 Eli Lilly And Company Thiazolinoazetidinones and process therefor
US4223133A (en) * 1979-02-01 1980-09-16 Eli Lilly And Company Cephalosporin reduction process
US4226986A (en) * 1979-02-01 1980-10-07 Eli Lilly And Company Process for halogenation of β-lactam compounds
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
US4281117A (en) * 1980-09-04 1981-07-28 Eli Lilly And Company Process for 3-chloro cephalosporin nucleus
US5159071A (en) * 1990-09-06 1992-10-27 Ranbaxy Laboratories Limited Process for the manufacture of 7-amino-3-exomethylene-3-cepham-4-carboxylic acid ester
US5350845A (en) * 1992-04-08 1994-09-27 Eli Lilly And Company Process for preparing 7-substituted-amino-3-hydroxy-3-cephem-4-protected carboxy-sulfoxide esters
IN181695B (ro) * 1992-08-10 1998-09-05 Ranbaxy Lab Ltd
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
KR100390551B1 (ko) * 1996-08-22 2003-11-17 주식회사 코오롱 3-할로메틸-3-세펨-4-카르복실레이트 1-옥사이드의 제조방법
CN101190921B (zh) * 2007-11-27 2010-05-19 吉林省石油化工设计研究院 一种对硝基苄基-7-苯氧基乙酰胺-3-外亚甲基头孢-4-羧酸酯-1-β-氧化物制备方法
CN102443014B (zh) * 2011-12-29 2014-07-09 上海右手医药科技开发有限公司 3-氯头孢菌素衍生物及其合成方法与在头孢克洛制备中的应用
CN103588790A (zh) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641014A (en) * 1968-10-03 1972-02-08 Lilly Co Eli Reduction of delta**3-cephalosporin sulfoxides
AR208068A1 (es) * 1973-02-23 1976-11-30 Lilly Co Eli Un procedimiento para preparar derivados de acidos 7-acilamido-3-halo-cefem-4-carboxilico los esteres y las sales farmaceuticamente aceptables de los mismos
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
YU36970B (en) * 1973-02-23 1984-08-31 Lilly Co Eli Process for obtaining 7-(amino)-acylamido-3-halocephalosporins
US3962227A (en) * 1973-02-23 1976-06-08 Eli Lilly And Company 3-halo cephalosporins

Also Published As

Publication number Publication date
FI66873B (fi) 1984-08-31
ES461587A1 (es) 1978-06-01
CS192588B2 (en) 1979-08-31
RO71908A (ro) 1981-11-24
BG28068A3 (en) 1980-02-25
FR2362145B1 (ro) 1980-02-15
NL7709055A (nl) 1978-02-20
HU179459B (en) 1982-10-28
FI772339A (fi) 1978-02-17
CH630924A5 (de) 1982-07-15
CA1099256A (en) 1981-04-14
IE45158B1 (en) 1982-06-30
DE2735454A1 (de) 1978-02-23
JPS5323994A (en) 1978-03-06
DE2735454C2 (ro) 1992-12-10
DD131858A5 (de) 1978-07-26
US4115643A (en) 1978-09-19
FR2362145A1 (fr) 1978-03-17
IL52416A0 (en) 1977-08-31
JPS6120556B2 (ro) 1986-05-22
IL52416A (en) 1980-02-29
SU1018586A3 (ru) 1983-05-15
GB1582044A (en) 1980-12-31
FI66873C (fi) 1984-12-10
IE45158L (en) 1978-02-16
PL200289A1 (pl) 1978-05-08
PL110242B1 (en) 1980-07-31

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: ELI LILLY AND CY

Effective date: 19970728