HU171237B - Sposob poluchenija proizvodnykh 4-/fenoksi-metil/-piperidina - Google Patents
Sposob poluchenija proizvodnykh 4-/fenoksi-metil/-piperidinaInfo
- Publication number
- HU171237B HU171237B HU76BO00001639A HUBO001639A HU171237B HU 171237 B HU171237 B HU 171237B HU 76BO00001639 A HU76BO00001639 A HU 76BO00001639A HU BO001639 A HUBO001639 A HU BO001639A HU 171237 B HU171237 B HU 171237B
- Authority
- HU
- Hungary
- Prior art keywords
- piperidine
- phenoxy
- methyl
- preparing derivatives
- derivatives
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- HRDXJKGNWSUIBT-UHFFFAOYSA-N methoxybenzene Chemical group [CH2]OC1=CC=CC=C1 HRDXJKGNWSUIBT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752549999 DE2549999A1 (de) | 1975-11-07 | 1975-11-07 | Piperidin-derivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU171237B true HU171237B (hu) | 1977-12-28 |
Family
ID=5961166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU76BO00001639A HU171237B (hu) | 1975-11-07 | 1976-11-01 | Sposob poluchenija proizvodnykh 4-/fenoksi-metil/-piperidina |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4243807A (en:Method) |
| JP (1) | JPS6055509B2 (en:Method) |
| AT (1) | AT352726B (en:Method) |
| BE (1) | BE847973A (en:Method) |
| CA (1) | CA1077942A (en:Method) |
| CH (3) | CH624102A5 (en:Method) |
| DD (1) | DD126942A5 (en:Method) |
| DE (1) | DE2549999A1 (en:Method) |
| DK (1) | DK494876A (en:Method) |
| FI (1) | FI763148A7 (en:Method) |
| FR (1) | FR2330678A1 (en:Method) |
| GB (1) | GB1502050A (en:Method) |
| HU (1) | HU171237B (en:Method) |
| IE (1) | IE43866B1 (en:Method) |
| IT (1) | IT1063618B (en:Method) |
| LU (1) | LU76141A1 (en:Method) |
| NL (1) | NL7612286A (en:Method) |
| SE (1) | SE7612234L (en:Method) |
| SU (3) | SU633473A3 (en:Method) |
| ZA (1) | ZA766381B (en:Method) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA848275B (en) * | 1983-12-28 | 1985-08-28 | Degussa | New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring |
| US4556664A (en) * | 1984-03-13 | 1985-12-03 | Gunnar A. K. Aberg | Method and composition for the treatment of cardiac arrhythmias |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
| US5231184A (en) * | 1987-11-23 | 1993-07-27 | Janssen Pharmaceutica N.V. | Pridazinamine derivatives |
| US4822778A (en) * | 1988-01-19 | 1989-04-18 | Gunnar Aberg | Membrane stabilizing phenoxy-piperidine compounds and pharmaceutical compositions employing such compounds |
| US5109002A (en) * | 1989-09-08 | 1992-04-28 | Du Pont Merck Pharmaceutical Company | Antipsychotic 1-cycloalkylpiperidines |
| IL99537A (en) * | 1990-09-27 | 1995-11-27 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical compositions containing them |
| NZ239846A (en) * | 1990-09-27 | 1994-11-25 | Merck & Co Inc | Sulphonamide derivatives and pharmaceutical compositions thereof |
| US5264420A (en) * | 1990-09-27 | 1993-11-23 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| FR2667317B1 (fr) * | 1990-10-02 | 1992-12-04 | Synthelabo | Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
| FI934894L (fi) * | 1991-05-07 | 1993-11-05 | Merck & Co Inc | Fibrinogenreceptorantagonister |
| US5321034A (en) * | 1991-05-07 | 1994-06-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5389631A (en) * | 1991-10-29 | 1995-02-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5416099A (en) * | 1991-10-29 | 1995-05-16 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5272158A (en) * | 1991-10-29 | 1993-12-21 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5358956A (en) * | 1992-10-14 | 1994-10-25 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| CA2144763A1 (en) * | 1992-10-14 | 1994-04-28 | George D. Hartman | Fibrinogen receptor antagonists |
| CA2150550A1 (en) * | 1992-12-01 | 1994-06-09 | Melissa S. Egbertson | Fibrinogen receptor antagonists |
| US5441952A (en) * | 1993-04-05 | 1995-08-15 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5334596A (en) * | 1993-05-11 | 1994-08-02 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5397791A (en) * | 1993-08-09 | 1995-03-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5821241A (en) * | 1994-02-22 | 1998-10-13 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5719144A (en) * | 1995-02-22 | 1998-02-17 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5750147A (en) | 1995-06-07 | 1998-05-12 | Emisphere Technologies, Inc. | Method of solubilizing and encapsulating itraconazole |
| KR100403246B1 (ko) * | 1995-09-28 | 2004-02-11 | 가켄 세이야쿠 가부시키가이샤 | ４-메틸렌피페리딘의제조방법 |
| US5789421A (en) * | 1995-10-26 | 1998-08-04 | Merck & Co., Inc. | Fibrinogen receptor antagonist |
| US5780480A (en) * | 1996-02-28 | 1998-07-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5889023A (en) * | 1996-05-10 | 1999-03-30 | Merck & Co., Inc. | Fibrinogen receptor antagonist |
| US5981584A (en) * | 1997-02-06 | 1999-11-09 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
| JP5405571B2 (ja) * | 2008-07-24 | 2014-02-05 | セラヴァンス， インコーポレーテッド | ３−（フェノキシフェニルメチル）ピロリジン化合物 |
| TWI461407B (zh) | 2008-11-14 | 2014-11-21 | Theravance Biopharma R & D Ip Llc | 製備４－〔２－（２－氟苯氧基甲基）苯基〕哌啶化合物之方法 |
| EP2419405A1 (en) * | 2009-04-15 | 2012-02-22 | Theravance, Inc. | 3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds |
| EP2454234B1 (en) * | 2009-07-13 | 2018-04-11 | Theravance Biopharma R&D IP, LLC | 3-phenoxymethylpyrrolidine compounds |
| WO2011011231A1 (en) | 2009-07-21 | 2011-01-27 | Theravance, Inc. | 3-phenoxymethylpyrrolidine compounds |
| US8778949B2 (en) * | 2010-01-11 | 2014-07-15 | Theravance Biopharma R&D Ip, Llc | 1-(2-phenoxymethylphenyl)piperazine compounds |
| EP2550252B1 (en) * | 2010-03-22 | 2015-05-06 | Theravance Biopharma R&D IP, LLC | 1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds |
| CA2811641A1 (en) | 2010-10-11 | 2012-04-19 | Theravance, Inc. | Serotonin reuptake inhibitors |
| WO2012075239A1 (en) | 2010-12-03 | 2012-06-07 | Theravance, Inc. | Serotonin reuptake inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1268951A (en) * | 1969-06-12 | 1972-03-29 | Pfizer Ltd | Phenoxy-amines |
| DE2245061A1 (de) * | 1972-09-14 | 1974-03-28 | Boehringer Mannheim Gmbh | Derivate des adenins |
| DE2401254A1 (de) * | 1974-01-11 | 1975-11-27 | Boehringer Mannheim Gmbh | Neue derivate von n hoch 6-substituierten adeninen |
| DE2550000A1 (de) * | 1975-11-07 | 1977-05-12 | Boehringer Mannheim Gmbh | Neue purin-derivate und verfahren zu ihrer herstellung |
-
1975
- 1975-11-07 DE DE19752549999 patent/DE2549999A1/de active Granted
-
1976
- 1976-10-25 ZA ZA766381A patent/ZA766381B/xx unknown
- 1976-10-28 CA CA264,608A patent/CA1077942A/en not_active Expired
- 1976-10-29 IE IE2394/76A patent/IE43866B1/en unknown
- 1976-11-01 US US05/737,518 patent/US4243807A/en not_active Expired - Lifetime
- 1976-11-01 HU HU76BO00001639A patent/HU171237B/hu not_active IP Right Cessation
- 1976-11-02 SU SU762415648A patent/SU633473A3/ru active
- 1976-11-02 DK DK494876A patent/DK494876A/da not_active Application Discontinuation
- 1976-11-03 FI FI763148A patent/FI763148A7/fi not_active Application Discontinuation
- 1976-11-03 CH CH1385576A patent/CH624102A5/de not_active IP Right Cessation
- 1976-11-03 SE SE7612234A patent/SE7612234L/xx not_active Application Discontinuation
- 1976-11-04 GB GB45916/76A patent/GB1502050A/en not_active Expired
- 1976-11-04 DD DD195610A patent/DD126942A5/xx unknown
- 1976-11-04 BE BE172068A patent/BE847973A/xx not_active IP Right Cessation
- 1976-11-05 JP JP51133139A patent/JPS6055509B2/ja not_active Expired
- 1976-11-05 NL NL7612286A patent/NL7612286A/xx not_active Application Discontinuation
- 1976-11-05 IT IT29083/76A patent/IT1063618B/it active
- 1976-11-05 LU LU76141A patent/LU76141A1/xx unknown
- 1976-11-05 AT AT823776A patent/AT352726B/de not_active IP Right Cessation
- 1976-11-05 FR FR7633389A patent/FR2330678A1/fr active Granted
-
1977
- 1977-10-21 SU SU772534003A patent/SU662009A3/ru active
- 1977-10-21 SU SU772534004A patent/SU867298A3/ru active
-
1980
- 1980-10-03 CH CH742480A patent/CH627166A5/de not_active IP Right Cessation
- 1980-10-03 CH CH742380A patent/CH625788A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL7612286A (nl) | 1977-05-10 |
| SU633473A3 (ru) | 1978-11-15 |
| IE43866L (en) | 1977-05-07 |
| DD126942A5 (en:Method) | 1977-08-24 |
| GB1502050A (en) | 1978-02-22 |
| FI763148A7 (en:Method) | 1977-05-08 |
| IE43866B1 (en) | 1981-06-17 |
| JPS6055509B2 (ja) | 1985-12-05 |
| CH627166A5 (en:Method) | 1981-12-31 |
| DE2549999A1 (de) | 1977-05-12 |
| ATA823776A (de) | 1979-03-15 |
| CH625788A5 (en:Method) | 1981-10-15 |
| BE847973A (fr) | 1977-05-04 |
| CH624102A5 (en:Method) | 1981-07-15 |
| DE2549999C2 (en:Method) | 1989-01-26 |
| US4243807A (en) | 1981-01-06 |
| SU867298A3 (ru) | 1981-09-23 |
| SU662009A3 (ru) | 1979-05-05 |
| DK494876A (da) | 1977-05-08 |
| FR2330678B1 (en:Method) | 1980-11-07 |
| AT352726B (de) | 1979-10-10 |
| JPS5259163A (en) | 1977-05-16 |
| LU76141A1 (en:Method) | 1977-05-18 |
| SE7612234L (sv) | 1977-05-07 |
| IT1063618B (it) | 1985-02-11 |
| ZA766381B (en) | 1977-10-26 |
| CA1077942A (en) | 1980-05-20 |
| FR2330678A1 (fr) | 1977-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |