HRP930675B1 - Process for the preparation of transdermal therapeutic system with buprenorphine as an active substance - Google Patents

Process for the preparation of transdermal therapeutic system with buprenorphine as an active substance

Info

Publication number
HRP930675B1
HRP930675B1 HRP-2260/90A HRP930675A HRP930675B1 HR P930675 B1 HRP930675 B1 HR P930675B1 HR P930675 A HRP930675 A HR P930675A HR P930675 B1 HRP930675 B1 HR P930675B1
Authority
HR
Croatia
Prior art keywords
buprenorphine
active substance
transdermal therapeutic
therapeutic system
weight
Prior art date
Application number
HRP-2260/90A
Other languages
English (en)
Inventor
Hans-Rainer Hoffmann
Original Assignee
Hans-Rainer Hoffmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6394373&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP930675(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hans-Rainer Hoffmann filed Critical Hans-Rainer Hoffmann
Publication of HRP930675A2 publication Critical patent/HRP930675A2/hr
Publication of HRP930675B1 publication Critical patent/HRP930675B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Laminated Bodies (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HRP-2260/90A 1989-11-29 1993-04-01 Process for the preparation of transdermal therapeutic system with buprenorphine as an active substance HRP930675B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3939376A DE3939376C1 (ja) 1989-11-29 1989-11-29
YU226090A YU47956B (sh) 1989-11-29 1990-11-27 Postupak za izradu transdermalnog terapijskog sistema sa buprenorphinom kao aktivnim sastojkom

Publications (2)

Publication Number Publication Date
HRP930675A2 HRP930675A2 (en) 1994-10-31
HRP930675B1 true HRP930675B1 (en) 1999-10-31

Family

ID=6394373

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP-2260/90A HRP930675B1 (en) 1989-11-29 1993-04-01 Process for the preparation of transdermal therapeutic system with buprenorphine as an active substance

Country Status (25)

Country Link
EP (1) EP0430019B1 (ja)
JP (1) JPH0818984B2 (ja)
KR (1) KR950015061B1 (ja)
AT (1) ATE135205T1 (ja)
AU (1) AU632182B2 (ja)
CA (1) CA2030178C (ja)
CZ (1) CZ282557B6 (ja)
DE (2) DE3939376C1 (ja)
DK (1) DK0430019T3 (ja)
ES (1) ES2086353T3 (ja)
FI (1) FI100379B (ja)
GR (1) GR3020177T3 (ja)
HR (1) HRP930675B1 (ja)
HU (1) HU206266B (ja)
IE (1) IE73247B1 (ja)
IL (1) IL96243A (ja)
MY (1) MY105347A (ja)
NO (1) NO303107B1 (ja)
NZ (1) NZ236191A (ja)
PL (1) PL165396B1 (ja)
PT (1) PT96028B (ja)
SI (1) SI9012260B (ja)
SK (1) SK279687B6 (ja)
YU (1) YU47956B (ja)
ZA (1) ZA909544B (ja)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5069909A (en) * 1990-06-20 1991-12-03 Cygnus Therapeutic Systems Transdermal administration of buprenorphine
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
DE4446600A1 (de) * 1994-12-24 1996-06-27 Lohmann Therapie Syst Lts Transdermale Resorption von Wirkstoffen aus unterkühlten Schmelzen
US6344211B1 (en) 1994-12-24 2002-02-05 Lts Lohmann Therapie-Systeme Gmbh Transdermal absorption of active substances from subcooled melts
JPH1036265A (ja) 1996-07-19 1998-02-10 Nitto Denko Corp ブプレノルフィン経皮吸収製剤
DE19705138A1 (de) * 1997-02-11 1998-08-13 Lohmann Therapie Syst Lts Dehnbares transdermales therapeutisches System
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
DE19738855C2 (de) 1997-09-05 2001-01-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit haftklebender Reservoirschicht und unidirektional elastischer Rückschicht
DE19828273B4 (de) * 1998-06-25 2005-02-24 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren
DE19850517B4 (de) 1998-11-03 2004-02-12 Lts Lohmann Therapie-Systeme Ag Verwendung eines wirkstoffhaltigen transdermalen therapeutischen Systems in einer Kombinationsbehandlung mit und ohne Ultraschall
DE19901085C2 (de) * 1999-01-14 2003-12-18 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit einer selbstklebenden Matrix, enthaltend organische Säure-Additionssalze von Alkaloiden des Morphin- bzw. Morphinantyps
DE19923551A1 (de) * 1999-05-21 2000-11-30 Lohmann Therapie Syst Lts Pharmazeutisches Präparat mit dem Wirkstoff Diamorphin und seine Verwendung in einem Verfahren zur Behandlung der Opiatsucht
DE10056014A1 (de) * 2000-11-11 2002-05-16 Beiersdorf Ag Mehrschichtige Trägerkonstruktion für wirkstofhaltige Pflastersyteme
DE10056012A1 (de) * 2000-11-11 2002-05-16 Beiersdorf Ag Flexible Barrierefolie für ein Trägermaterial für medizinische Zwecke
JP4194277B2 (ja) 2002-01-25 2008-12-10 久光製薬株式会社 架橋ポリマーを主成分とする粘着性成形体の製造方法
DE50307717D1 (de) * 2002-08-09 2007-08-30 Gruenenthal Gmbh Opiod-rezeptor-antagonisten in transdermalen systemen mit buprenorphin
DE10237057A1 (de) * 2002-08-09 2004-03-25 Grünenthal GmbH Opioid-Rezeptor-Antagonisten in Pflasterformulierungen
KR101152183B1 (ko) 2003-03-31 2012-06-15 타이탄 파머슈티컬즈 인코퍼레이티드 도파민 아고니스트의 지속 방출을 위한 이식가능한 폴리머디바이스
MXPA06000991A (es) * 2003-07-25 2006-04-11 Euro Celtique Sa Tratamiento de supresion de la dependencia.
DE102004009903A1 (de) 2004-02-26 2005-09-22 Grünenthal GmbH Pflaster mit reduzierter Hautirritation
EP1743638A1 (en) 2005-07-15 2007-01-17 Laboratorios Del Dr. Esteve, S.A. Pharmaceutical formulations of substituted pyrazoline compounds
DE102006057083A1 (de) 2005-12-05 2007-06-28 Lg Electronics Inc. Beleuchtungsvorrichtung für einen Kühlschrank
DE102006054731B4 (de) * 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
US9844515B2 (en) 2010-11-17 2017-12-19 Hexal Ag Transdermal therapeutic system comprising buprenorphine
DE102011076653A1 (de) 2011-05-27 2012-11-29 Acino Ag Transdermales therapeutisches System enthaltend Buprenorphin und eine alpha-Hydroxysäure
AR089201A1 (es) * 2011-12-12 2014-08-06 Lohmann Therapie Syst Lts Sistema de suministro transdermico
DE102012000369A1 (de) 2012-01-11 2013-07-11 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System mit Cholinesterase-Hemmer
PT2810646T (pt) 2013-06-04 2016-10-05 Lts Lohmann Therapie Systeme Ag Sistema de administração transdérmica
DE102014013448A1 (de) 2014-09-16 2016-03-17 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales Therapeutisches System umfassend Buprenorphin
US9656441B2 (en) 2015-01-08 2017-05-23 Alfred E. Tiefenbacher ( Gmbh & Co. Kg) Transdermal patch
EP3067050A1 (en) 2015-03-13 2016-09-14 Acino AG Transdermal therapeutic system with an overtape comprising two adhesive layers
CN109045341A (zh) * 2018-05-07 2018-12-21 武汉兴嘉业堂医疗科技发展有限公司 一种活血止痛压敏胶及其制备方法、应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464378A (en) * 1981-04-28 1984-08-07 University Of Kentucky Research Foundation Method of administering narcotic antagonists and analgesics and novel dosage forms containing same
JPS60123417A (ja) * 1983-12-07 1985-07-02 Nitto Electric Ind Co Ltd 薬物投与部材
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4806341A (en) * 1985-02-25 1989-02-21 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration
DE3634016A1 (de) * 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung
JPS632533A (ja) * 1986-06-23 1988-01-07 Yamakawa Sangyo Kk 精密鋳造用鋳物砂
CH672888A5 (ja) * 1986-11-07 1990-01-15 Mepha Ag
EP0282156B1 (en) * 1987-03-09 1991-04-17 Alza Corporation Composition for the prevention of contact allergy by coadministration of a corticosteroid with a sensitizing drug
EP0375689B1 (en) * 1987-06-01 1992-08-12 Warner-Lambert Company A pharmaceutical composition adapted for transdermal delivery of an opoid drug.
DE3843237A1 (de) * 1988-12-22 1990-07-05 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit einem antiadipositum als aktivem bestandteil

Also Published As

Publication number Publication date
JPH03193732A (ja) 1991-08-23
PT96028B (pt) 1998-02-27
HRP930675A2 (en) 1994-10-31
JPH0818984B2 (ja) 1996-02-28
CZ282557B6 (cs) 1997-08-13
KR950015061B1 (ko) 1995-12-21
HUT55643A (en) 1991-06-28
IL96243A (en) 1994-11-28
IE73247B1 (en) 1997-05-21
ZA909544B (en) 1992-08-26
CA2030178C (en) 1995-08-15
SI9012260B (sl) 1998-06-30
NO905103L (no) 1991-05-30
NZ236191A (en) 1993-05-26
DE3939376C1 (ja) 1991-05-08
EP0430019A3 (en) 1991-09-18
AU632182B2 (en) 1992-12-17
IL96243A0 (en) 1991-08-16
EP0430019A2 (de) 1991-06-05
FI905892A0 (fi) 1990-11-29
DE59010192D1 (de) 1996-04-18
PL165396B1 (en) 1994-12-30
EP0430019B1 (de) 1996-03-13
ATE135205T1 (de) 1996-03-15
DK0430019T3 (da) 1996-07-22
CS9005598A2 (en) 1991-12-17
GR3020177T3 (en) 1996-09-30
AU6569990A (en) 1991-06-06
YU47956B (sh) 1996-07-24
YU226090A (sh) 1992-12-21
PT96028A (pt) 1991-09-13
CA2030178A1 (en) 1991-05-30
IE904290A1 (en) 1991-06-05
FI100379B (fi) 1997-11-28
KR910009249A (ko) 1991-06-28
SI9012260A (en) 1997-10-31
NO905103D0 (no) 1990-11-26
SK279687B6 (sk) 1999-02-11
NO303107B1 (no) 1998-06-02
ES2086353T3 (es) 1996-07-01
FI905892A (fi) 1991-05-30
PL287989A1 (en) 1991-09-09
MY105347A (en) 1994-09-30
HU206266B (en) 1992-10-28

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