HRP920162B1 - Forms of preparations for acid-instable active substances for oral use - Google Patents

Forms of preparations for acid-instable active substances for oral use

Info

Publication number
HRP920162B1
HRP920162B1 HR01788/91-0A HRP920162A HRP920162B1 HR P920162 B1 HRP920162 B1 HR P920162B1 HR P920162 A HRP920162 A HR P920162A HR P920162 B1 HRP920162 B1 HR P920162B1
Authority
HR
Croatia
Prior art keywords
preparations
acid
forms
active substances
oral use
Prior art date
Application number
HR01788/91-0A
Other languages
English (en)
Inventor
Hartmut Ney
Original Assignee
Hartmut Ney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4218617&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP920162(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hartmut Ney filed Critical Hartmut Ney
Publication of HRP920162A2 publication Critical patent/HRP920162A2/xx
Publication of HRP920162B1 publication Critical patent/HRP920162B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
HR01788/91-0A 1991-06-17 1992-06-12 Forms of preparations for acid-instable active substances for oral use HRP920162B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH178891 1991-06-17

Publications (2)

Publication Number Publication Date
HRP920162A2 HRP920162A2 (en) 1996-08-31
HRP920162B1 true HRP920162B1 (en) 1998-08-31

Family

ID=4218617

Family Applications (1)

Application Number Title Priority Date Filing Date
HR01788/91-0A HRP920162B1 (en) 1991-06-17 1992-06-12 Forms of preparations for acid-instable active substances for oral use

Country Status (33)

Country Link
US (1) US5997903A (cs)
EP (2) EP0519365A1 (cs)
JP (1) JP3338052B2 (cs)
KR (1) KR100254021B1 (cs)
CN (1) CN1037932C (cs)
AT (1) ATE144416T1 (cs)
AU (1) AU683411B2 (cs)
BG (1) BG61796B1 (cs)
CA (2) CA2109697C (cs)
CZ (1) CZ281697B6 (cs)
DE (2) DE59207438D1 (cs)
DK (1) DK0589981T3 (cs)
ES (1) ES2096080T3 (cs)
FI (1) FI101598B1 (cs)
GR (1) GR3022154T3 (cs)
HR (1) HRP920162B1 (cs)
IE (1) IE77640B1 (cs)
IL (1) IL102096A (cs)
LV (1) LV11982B (cs)
MX (1) MX9202961A (cs)
NO (1) NO303714B1 (cs)
NZ (1) NZ243147A (cs)
PL (1) PL169951B1 (cs)
RO (1) RO117502B1 (cs)
RU (1) RU2089180C1 (cs)
SI (1) SI9200111A (cs)
SK (1) SK278566B6 (cs)
TW (1) TW224429B (cs)
UA (1) UA32525C2 (cs)
WO (1) WO1992022284A1 (cs)
YU (1) YU48263B (cs)
ZA (1) ZA924386B (cs)
ZW (1) ZW9392A1 (cs)

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AU4504000A (en) * 1993-04-27 2000-09-07 Sepracor, Inc. Methods and compositions for treating gastric disorders using optically pure (-) pantoprazole
SE9301489D0 (sv) * 1993-04-30 1993-04-30 Ab Astra Veterinary composition
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
DE4324014C2 (de) * 1993-07-17 1995-06-08 Byk Gulden Lomberg Chem Fab Verfahren zur Herstellung einer in Wasser rekonstituierbaren Zubereitung
TW280770B (cs) 1993-10-15 1996-07-11 Takeda Pharm Industry Co Ltd
DK1078628T3 (da) * 1994-07-08 2009-02-23 Astrazeneca Ab Tabletteret flerenhedsdoseringsform
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
ES2094694B1 (es) * 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US5945124A (en) * 1995-07-05 1999-08-31 Byk Gulden Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole
EP0854718B1 (en) * 1995-09-21 2004-03-10 Pharma Pass II LLC Novel composition containing an acid-labile benzimidazole and process for its preparation
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9702000D0 (sv) * 1997-05-28 1997-05-28 Astra Ab New pharmaceutical formulation
SI9700186B (sl) 1997-07-14 2006-10-31 Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin
ES2137862B1 (es) * 1997-07-31 2000-09-16 Intexim S A Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion.
IN186245B (cs) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
AU751066B2 (en) * 1997-12-08 2002-08-08 Nycomed Gmbh Novel administration form comprising an acid-labile active compound
DK173431B1 (da) 1998-03-20 2000-10-23 Gea Farmaceutisk Fabrik As Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs
EP1004305B1 (en) * 1998-04-20 2011-09-28 Eisai R&D Management Co., Ltd. Stabilized compositions containing benzimidazole-type compounds
JP4127740B2 (ja) * 1998-04-20 2008-07-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 安定化したベンズイミダゾール系化合物含有組成物
CA2323680C (en) 1998-05-18 2007-05-22 Takeda Chemical Industries, Ltd. Orally disintegrable tablets
ZA9810765B (en) * 1998-05-28 1999-08-06 Ranbaxy Lab Ltd Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
US7041313B1 (en) * 1998-08-12 2006-05-09 Altana Pharma Ag Oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles
DE19843413C1 (de) * 1998-08-18 2000-03-30 Byk Gulden Lomberg Chem Fab Neue Salzform von Pantoprazol
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SE9902386D0 (sv) * 1999-06-22 1999-06-22 Astra Ab New formulation
ES2168043B1 (es) 1999-09-13 2003-04-01 Esteve Labor Dr Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido.
ATE369857T1 (de) 1999-10-20 2007-09-15 Eisai R&D Man Co Ltd Methode zur stabilisierung von benzimidazol- verbindungen
DE19959419A1 (de) 1999-12-09 2001-06-21 Ratiopharm Gmbh Stabile galenische Zubereitungen umfassend ein Benzimidazol und Verfahren zu ihrer Herstellung
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WO2001045668A2 (en) * 1999-12-20 2001-06-28 Schering Corporation Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine
AU2276801A (en) * 1999-12-20 2001-07-03 Schering Corporation Extended release oral dosage composition
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
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AU2002330164A1 (en) 2001-09-28 2003-04-07 Mcneil-Ppc, Inc. Modified release dosage forms
US20050163846A1 (en) * 2001-11-21 2005-07-28 Eisai Co., Ltd. Preparation composition containing acid-unstable physiologically active compound, and process for producing same
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US8449911B2 (en) * 2003-03-12 2013-05-28 Takeda Pharmaceutical Company Limited Drug composition having active ingredient adhered at high concentration to spherical core
CL2004000983A1 (es) * 2003-05-08 2005-03-04 Altana Pharma Ag Composicion farmaceutica oral en forma de tableta que comprende a pantoprazol magnetico dihidratado, en donde la forma de tableta esta compuesto por un nucleo, una capa intermedia y una capa exterior; y uso de la composicion farmaceutica en ulceras y
PE20050150A1 (es) * 2003-05-08 2005-03-22 Altana Pharma Ag Una forma de dosificacion que contiene (s)-pantoprazol como ingrediente activo
AU2003245033A1 (en) * 2003-05-08 2004-11-26 Podili Khadgapathi An improved and stable pharmaceutical composition containing substituted benzimidazoles and a process for its preparation
CA2532310A1 (en) * 2003-07-17 2005-02-03 Dr. Reddy's Laboratories, Inc. Pharmaceutical compositions having a swellable coating
US20050042277A1 (en) * 2003-07-17 2005-02-24 Irukulla Srinivas Pharmaceutical compositions having a swellable coating
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US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
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US20050175689A1 (en) * 2003-10-27 2005-08-11 Yamanouchi Pharmaceutical Co., Ltd. Coated fine particles containing drug for intrabuccally fast disintegrating tablet
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WO2005046634A2 (de) * 2003-11-14 2005-05-26 Siegfried Generics International Ag Magensaftresistente verabreichungsform
HU227317B1 (en) * 2003-11-25 2011-03-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Enteric coated tablet containing pantoprazole
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ATE531361T1 (de) 2004-05-07 2011-11-15 Nycomed Gmbh Neue pharmazeutische dosierform und herstellungsverfahren
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US20060024362A1 (en) * 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
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BR112015016917B1 (pt) 2013-01-15 2022-08-30 Ironwood Pharmaceuticals, Inc Forma de dosagem oral de retenção gástrica, e, uso de um sequestrante de ácido biliar
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CN108065443B (zh) * 2017-12-30 2020-02-28 厦门金达威维生素有限公司 斥水型双包被微胶囊及其制备方法
CN114569579B (zh) 2020-12-02 2023-10-31 丽珠医药集团股份有限公司 肠溶微丸、其制备方法和包含它的制剂
JP2025532389A (ja) 2022-10-04 2025-09-29 ザビリュク，アルセニー 大動脈弁の石灰化の抑制

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
JPH0768125B2 (ja) * 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤

Also Published As

Publication number Publication date
NO303714B1 (no) 1998-08-24
DE4219390A1 (de) 1992-12-24
SI9200111A (en) 1992-12-31
NO934648D0 (no) 1993-12-16
MX9202961A (es) 1993-02-01
BG61796B1 (bg) 1998-06-30
EP0589981B1 (de) 1996-10-23
CZ281697B6 (cs) 1996-12-11
UA32525C2 (uk) 2001-02-15
EP0519365A1 (de) 1992-12-23
CA2109697C (en) 2005-11-22
LV11982A (lv) 1998-03-20
JP3338052B2 (ja) 2002-10-28
TW224429B (cs) 1994-06-01
ATE144416T1 (de) 1996-11-15
CN1037932C (zh) 1998-04-08
DK0589981T3 (da) 1997-03-17
WO1992022284A1 (de) 1992-12-23
IL102096A (en) 1996-06-18
NO934648L (no) 1993-12-16
FI935677L (fi) 1993-12-16
AU1974692A (en) 1993-01-12
ZW9392A1 (en) 1993-02-17
GR3022154T3 (en) 1997-03-31
FI935677A0 (fi) 1993-12-16
DE59207438D1 (de) 1996-11-28
ZA924386B (en) 1993-02-24
JPH06508118A (ja) 1994-09-14
CA2524168A1 (en) 1992-12-23
HK1005851A1 (en) 1999-01-29
IL102096A0 (en) 1993-01-14
US5997903A (en) 1999-12-07
SK128793A3 (en) 1994-06-08
AU683411B2 (en) 1997-11-13
KR940701256A (ko) 1994-05-28
IE921733A1 (en) 1992-11-18
EP0589981A1 (de) 1994-04-06
YU57692A (sh) 1995-03-27
RO117502B1 (ro) 2002-04-30
SK278566B6 (en) 1997-10-08
BG98286A (bg) 1994-08-30
CA2109697A1 (en) 1992-12-23
RU2089180C1 (ru) 1997-09-10
FI101598B (fi) 1998-07-31
IE77640B1 (en) 1997-12-31
HRP920162A2 (en) 1996-08-31
PL169951B1 (pl) 1996-09-30
YU48263B (sh) 1997-09-30
CZ276493A3 (en) 1994-07-13
FI101598B1 (fi) 1998-07-31
ES2096080T3 (es) 1997-03-01
KR100254021B1 (ko) 2000-05-01
CN1067809A (zh) 1993-01-13
LV11982B (lv) 1998-09-20
NZ243147A (en) 1995-12-21

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