HRP20220708T4 - Postupci liječenja fibroida maternice i endometrioze - Google Patents

Postupci liječenja fibroida maternice i endometrioze Download PDF

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Publication number
HRP20220708T4
HRP20220708T4 HRP20220708TT HRP20220708T HRP20220708T4 HR P20220708 T4 HRP20220708 T4 HR P20220708T4 HR P20220708T T HRP20220708T T HR P20220708TT HR P20220708 T HRP20220708 T HR P20220708T HR P20220708 T4 HRP20220708 T4 HR P20220708T4
Authority
HR
Croatia
Prior art keywords
compound
use according
endometriosis
treatment
combination
Prior art date
Application number
HRP20220708TT
Other languages
English (en)
Croatian (hr)
Inventor
Brendan Mark JOHNSON
Lynn Seely
Mudd, Jr.
Susan Wollowitz
Mark Hibberd
Masataka TANIMOTO
Vijaykumar Reddy RAJASEKHAR
Mayukh Vasant SUKHATME
Original Assignee
Sumitomo Pharma Switzerland Gmbh
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60915460&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20220708(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Pharma Switzerland Gmbh, Takeda Pharmaceutical Company Limited filed Critical Sumitomo Pharma Switzerland Gmbh
Publication of HRP20220708T1 publication Critical patent/HRP20220708T1/hr
Publication of HRP20220708T4 publication Critical patent/HRP20220708T4/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Surgical Instruments (AREA)
HRP20220708TT 2016-09-30 2017-09-29 Postupci liječenja fibroida maternice i endometrioze HRP20220708T4 (hr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662402150P 2016-09-30 2016-09-30
US201662402034P 2016-09-30 2016-09-30
US201662402055P 2016-09-30 2016-09-30
US201762492839P 2017-05-01 2017-05-01
US201762528409P 2017-07-03 2017-07-03
EP17823018.1A EP3518933B2 (en) 2016-09-30 2017-09-29 Methods of treating uterine fibroids and endometriosis
PCT/EP2017/074907 WO2018060501A2 (en) 2016-09-30 2017-09-29 Methods of treating uterine fibroids and endometriosis

Publications (2)

Publication Number Publication Date
HRP20220708T1 HRP20220708T1 (hr) 2022-07-22
HRP20220708T4 true HRP20220708T4 (hr) 2025-04-25

Family

ID=60915460

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20220708TT HRP20220708T4 (hr) 2016-09-30 2017-09-29 Postupci liječenja fibroida maternice i endometrioze

Country Status (24)

Country Link
US (4) US11033551B2 (OSRAM)
EP (2) EP4094766B1 (OSRAM)
JP (1) JP7043503B2 (OSRAM)
CN (1) CN110312512B (OSRAM)
AU (2) AU2017336363B2 (OSRAM)
BR (1) BR112019006227A2 (OSRAM)
CA (1) CA3038879A1 (OSRAM)
CY (1) CY1125254T1 (OSRAM)
DK (1) DK3518933T4 (OSRAM)
ES (2) ES3018413T3 (OSRAM)
FI (1) FI3518933T4 (OSRAM)
HR (1) HRP20220708T4 (OSRAM)
HU (2) HUE072130T2 (OSRAM)
IL (2) IL265700B2 (OSRAM)
LT (1) LT3518933T (OSRAM)
MD (1) MD3518933T4 (OSRAM)
MX (1) MX2019003726A (OSRAM)
NZ (1) NZ752916A (OSRAM)
PL (2) PL3518933T5 (OSRAM)
PT (1) PT3518933T (OSRAM)
RS (1) RS63300B2 (OSRAM)
SI (1) SI3518933T2 (OSRAM)
SM (1) SMT202200254T1 (OSRAM)
WO (1) WO2018060501A2 (OSRAM)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3518933T2 (sl) 2016-09-30 2025-05-30 Sumitomo Pharma Switzerland Gmbh Metode zdravljenja materničnih miom in endometrioze
WO2018060463A2 (en) 2016-09-30 2018-04-05 Myovant Sciences Gmbh Treatment of prostate cancer
JP7292566B2 (ja) 2017-06-05 2023-06-19 キッセイ薬品工業株式会社 子宮筋腫を治療し、月経失血を低下させるゴナドトロピン放出ホルモンアンタゴニスト投与計画
MA49256A (fr) 2017-06-05 2021-05-26 ObsEva SA Schémas posologiques comprenant un antagoniste de l'hormone de libération des gonadotrophines pour le traitement de l'endométriose
BR112020021276A2 (pt) * 2018-04-19 2021-01-26 Abbvie Inc. métodos de tratamento de sangramento menstrual intenso
MA54058A (fr) 2018-10-29 2021-09-08 ObsEva SA Compositions et méthodes de traitement de l'endométriose interne et de l'endométriose rectovaginale
RU2711658C1 (ru) * 2019-04-16 2020-01-20 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт акушерства, гинекологии и репродуктологии имени Д.О. Отта" Способ лечения наружного генитального эндометриоза
CN110194776B (zh) * 2019-06-27 2021-05-28 四川伊诺达博医药科技有限公司 一种瑞卢戈利的合成方法
WO2021023877A2 (en) * 2019-08-08 2021-02-11 ObsEva S.A. Compositions and methods for the treatment of estrogen-dependent disorders
JP2022551316A (ja) * 2019-10-10 2022-12-08 ミオバント サイエンシズ ゲーエムベーハー N-(4-(1-(2,6-ジフルオロベンジル)-5-((ジメチルアミノ)メチル)-3-(6-メトキシ-3-ピリダジニル)-2,4-ジオキソ-1,2,3,4-テトラヒドロチエノ[2,3-d]ピリミジン-6-イル)フェニル)-N’-メトキシ尿素の結晶形
CN115175912B (zh) * 2019-10-10 2025-04-11 住友制药瑞士有限公司 N-(4-(1-(2,6-二氟苄基)-5-((二甲基氨基)甲基)-3-(6-甲氧基-3-哒嗪基)-2,4-二氧代-1,2,3,4-四氢噻吩并[2,3-d]嘧啶-6-基)苯基)-n′-甲氧基脲的结晶溶剂化形式
CA3172074A1 (en) * 2020-02-19 2021-08-26 Aspira Women's Health Inc. Compositions for endometriosis assessment having improved specificity
CN113384581B (zh) * 2020-03-12 2023-11-14 成都倍特药业股份有限公司 一种包含促性腺激素释放激素拮抗剂的药物组合物
MX2022015003A (es) 2020-05-29 2023-03-03 Myovant Sciences Gmbh Formas de dosificacion oral solidas de combinacion de antagonistas de la hormona liberadora de gonadotropina.
JP2023549196A (ja) 2020-11-11 2023-11-22 ミオバント サイエンシズ ゲーエムベーハー レルゴリクスの投与方法
WO2023066941A1 (en) 2021-10-18 2023-04-27 Myovant Sciences Gmbh Crystalline form of an ethanol solvate of n-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea
CN117069735A (zh) * 2022-05-10 2023-11-17 北京海美源医药科技有限公司 一种高效合成瑞卢戈利的方法和其应用
WO2024015934A2 (en) * 2022-07-13 2024-01-18 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods of diagnostic screening and early detection of adenomyosis
TW202428262A (zh) * 2022-11-09 2024-07-16 美商坦帕斯醫療公司 三唑酮化合物及其用途
WO2025106820A1 (en) * 2023-11-16 2025-05-22 University Of South Florida Method of preventing progesterone contraceptive-induced abnormal uterine bleeding (aub)

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US492839A (en) 1893-03-07 Key for brake-shoes
US402034A (en) 1889-04-23 Dumping-wagon
US528409A (en) 1894-10-30 Denis ahern
US402055A (en) 1889-04-23 Water-motor
US402150A (en) 1889-04-30 Broadcast seed-sower
FR2512732A1 (fr) 1981-09-14 1983-03-18 Raffinage Cie Francaise Procede de fabrication d'objets composes d'un materiau rigide expanse a base de polychlorure de vinyle, objets obtenus par ce procede et leurs applications
US5340585A (en) 1991-04-12 1994-08-23 University Of Southern California Method and formulations for use in treating benign gynecological disorders
ECSP961635A (es) 1996-01-11 1997-06-27 Desprendimiento controlado de esteroides del recubrimiento de azucar
ECSP971998A (es) 1997-01-15 1998-04-07 Desprendimiento controlado de esteroides del recubrimiento de azucar
DE19815060A1 (de) 1998-04-03 1999-10-14 Jenapharm Gmbh Pharmazeutische Präparate zur Therapie von Nebenwirkungen während und/oder nach einer GnRHa-Therapie
US6265393B1 (en) * 1998-08-07 2001-07-24 Heinrichs William Leroy Prevention of endometriosis signs or symptons
TWI225863B (en) 1999-03-24 2005-01-01 Takeda Chemical Industries Ltd Thienopyrimidine compounds, their production and use
US6297379B1 (en) 1999-03-24 2001-10-02 Takeda Chemical Industries, Ltd. Thienopyrimidine compounds, their production and use
US6849738B2 (en) 2000-02-29 2005-02-01 Takeda Chemical Industries, Ltd. Processes for the production of thienopyrimidine derivatives
US7569570B2 (en) 2002-01-30 2009-08-04 Takeda Pharmaceutical Company Limited Thienopyrimidines, process for preparing the same and use thereof
CN101153042A (zh) 2003-01-29 2008-04-02 武田药品工业株式会社 噻吩并嘧啶化合物及其用途
ES2314448T3 (es) 2003-07-07 2009-03-16 Neurocrine Biosciences, Inc. Derivados de pirimidina-2,4-diona como antagonistas del receptor de la hormona de liberacion de la gonadotropina.
MY151322A (en) 2004-04-30 2014-05-15 Bayer Ip Gmbh Management of breakthrough bleeding in extended hormonal contraceptive regimens
US20090048273A1 (en) 2005-07-22 2009-02-19 Takeda Pharmaceutical Company Limited Premature ovulation preventive agent
TWI386417B (zh) 2005-12-22 2013-02-21 Takeda Pharmaceutical 轉移抑素衍生物及其用途
EA017029B1 (ru) 2007-04-06 2012-09-28 Ньюрокрайн Байосайенсиз, Инк. Антагонисты рецептора гонадотропин-рилизинг-фактора и способы их применения
US8765948B2 (en) 2007-11-07 2014-07-01 Neurocrine Biosciences, Inc. Processes for the preparation of uracil derivatives
JPWO2010026993A1 (ja) 2008-09-03 2012-02-02 武田薬品工業株式会社 製剤における吸収性改善方法および吸収性が改善された製剤
US9427418B2 (en) 2009-02-23 2016-08-30 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
US9624161B2 (en) 2009-02-23 2017-04-18 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
SG186333A1 (en) 2010-06-16 2013-01-30 Endorech Inc Methods of treating or preventing estrogen-related diseases
JP2012077020A (ja) 2010-09-30 2012-04-19 Mochida Pharmaceut Co Ltd ゲスターゲンとGnRHアンタゴニストとの組合せ医薬
RS58703B1 (sr) 2012-09-28 2019-06-28 Takeda Pharmaceuticals Co Metoda proizvodnje derivata tienopirimidina
IL241595B2 (en) * 2013-03-15 2025-10-01 Abbvie Inc Composition for use in methods of treating heavy menstrual bleeding associated with uterine fibroids
JP6730978B2 (ja) 2015-02-26 2020-07-29 武田薬品工業株式会社 固形製剤
HK1258062A1 (zh) 2015-09-01 2019-11-01 Abbvie Inc. 给予恶拉戈利的方法
SI3518933T2 (sl) 2016-09-30 2025-05-30 Sumitomo Pharma Switzerland Gmbh Metode zdravljenja materničnih miom in endometrioze
WO2018060463A2 (en) 2016-09-30 2018-04-05 Myovant Sciences Gmbh Treatment of prostate cancer
MA49256A (fr) 2017-06-05 2021-05-26 ObsEva SA Schémas posologiques comprenant un antagoniste de l'hormone de libération des gonadotrophines pour le traitement de l'endométriose
CN115175912B (zh) 2019-10-10 2025-04-11 住友制药瑞士有限公司 N-(4-(1-(2,6-二氟苄基)-5-((二甲基氨基)甲基)-3-(6-甲氧基-3-哒嗪基)-2,4-二氧代-1,2,3,4-四氢噻吩并[2,3-d]嘧啶-6-基)苯基)-n′-甲氧基脲的结晶溶剂化形式
JP2022551316A (ja) 2019-10-10 2022-12-08 ミオバント サイエンシズ ゲーエムベーハー N-(4-(1-(2,6-ジフルオロベンジル)-5-((ジメチルアミノ)メチル)-3-(6-メトキシ-3-ピリダジニル)-2,4-ジオキソ-1,2,3,4-テトラヒドロチエノ[2,3-d]ピリミジン-6-イル)フェニル)-N’-メトキシ尿素の結晶形
MX2022015003A (es) 2020-05-29 2023-03-03 Myovant Sciences Gmbh Formas de dosificacion oral solidas de combinacion de antagonistas de la hormona liberadora de gonadotropina.
JP2023549196A (ja) 2020-11-11 2023-11-22 ミオバント サイエンシズ ゲーエムベーハー レルゴリクスの投与方法
WO2023066941A1 (en) 2021-10-18 2023-04-27 Myovant Sciences Gmbh Crystalline form of an ethanol solvate of n-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea

Also Published As

Publication number Publication date
PL3518933T3 (pl) 2022-06-20
US20240165118A1 (en) 2024-05-23
US11793812B2 (en) 2023-10-24
US11957684B2 (en) 2024-04-16
HUE059101T2 (hu) 2022-10-28
SI3518933T1 (sl) 2022-06-30
PT3518933T (pt) 2022-05-10
US20190262346A1 (en) 2019-08-29
ES2912929T3 (es) 2022-05-30
EP3518933B1 (en) 2022-03-16
HRP20220708T1 (hr) 2022-07-22
MD3518933T2 (ro) 2022-07-31
BR112019006227A2 (pt) 2019-06-18
AU2022241582A1 (en) 2022-10-27
WO2018060501A2 (en) 2018-04-05
FI3518933T4 (fi) 2025-05-14
PL4094766T3 (pl) 2025-07-28
IL265700B1 (en) 2023-03-01
US20210401841A1 (en) 2021-12-30
IL265700B2 (en) 2023-07-01
AU2022241582C1 (en) 2024-11-28
RS63300B2 (sr) 2025-05-30
SMT202200254T1 (it) 2022-07-21
US11033551B2 (en) 2021-06-15
ES3018413T3 (es) 2025-05-16
EP3518933B2 (en) 2025-02-26
EP4094766A1 (en) 2022-11-30
DK3518933T3 (da) 2022-05-30
EP3518933A2 (en) 2019-08-07
RS63300B1 (sr) 2022-07-29
IL300580A (en) 2023-04-01
NZ752916A (en) 2022-09-30
IL300580B2 (en) 2025-11-01
WO2018060501A3 (en) 2018-05-11
AU2017336363B2 (en) 2022-08-04
JP2019529575A (ja) 2019-10-17
AU2017336363A1 (en) 2019-05-16
SI3518933T2 (sl) 2025-05-30
CA3038879A1 (en) 2018-04-05
AU2022241582B2 (en) 2024-06-13
LT3518933T (lt) 2022-06-10
JP7043503B2 (ja) 2022-03-29
CN110312512B (zh) 2023-05-09
EP4094766B1 (en) 2025-04-02
IL265700A (en) 2019-05-30
PL3518933T5 (pl) 2025-05-05
MD3518933T4 (ro) 2025-10-31
MX2019003726A (es) 2019-09-26
ES2912929T5 (en) 2025-05-09
US20220370462A1 (en) 2022-11-24
DK3518933T4 (da) 2025-04-22
CN110312512A (zh) 2019-10-08
CY1125254T1 (el) 2024-02-16
IL300580B1 (en) 2025-07-01
HUE072130T2 (hu) 2025-10-28

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