HRP20211762T1 - Derivati benzoksaborola za liječenje bakterijskih infekcija - Google Patents
Derivati benzoksaborola za liječenje bakterijskih infekcija Download PDFInfo
- Publication number
- HRP20211762T1 HRP20211762T1 HRP20211762TT HRP20211762T HRP20211762T1 HR P20211762 T1 HRP20211762 T1 HR P20211762T1 HR P20211762T T HRP20211762T T HR P20211762TT HR P20211762 T HRP20211762 T HR P20211762T HR P20211762 T1 HRP20211762 T1 HR P20211762T1
- Authority
- HR
- Croatia
- Prior art keywords
- solvate
- hydrate
- salt
- compound according
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38059610P | 2010-09-07 | 2010-09-07 | |
| EP17176654.6A EP3251678B1 (en) | 2010-09-07 | 2011-09-07 | Benzoxaborole derivatives for treating bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20211762T1 true HRP20211762T1 (hr) | 2022-02-18 |
Family
ID=44653589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20211762TT HRP20211762T1 (hr) | 2010-09-07 | 2011-09-07 | Derivati benzoksaborola za liječenje bakterijskih infekcija |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US8703742B2 (enExample) |
| EP (2) | EP3251678B1 (enExample) |
| JP (4) | JP5952280B2 (enExample) |
| KR (2) | KR101949423B1 (enExample) |
| CN (2) | CN103140228A (enExample) |
| AU (1) | AU2011299243C1 (enExample) |
| BR (1) | BR112013005426B1 (enExample) |
| CA (1) | CA2810021C (enExample) |
| CY (1) | CY1124728T1 (enExample) |
| DK (2) | DK3251678T3 (enExample) |
| EA (2) | EA033311B1 (enExample) |
| ES (2) | ES2635333T3 (enExample) |
| HR (1) | HRP20211762T1 (enExample) |
| HU (1) | HUE059033T2 (enExample) |
| IL (2) | IL225000A (enExample) |
| LT (1) | LT3251678T (enExample) |
| MX (1) | MX338209B (enExample) |
| PL (1) | PL3251678T3 (enExample) |
| PT (1) | PT3251678T (enExample) |
| RS (1) | RS62548B1 (enExample) |
| SG (2) | SG187969A1 (enExample) |
| SI (1) | SI3251678T1 (enExample) |
| SM (1) | SMT202100643T1 (enExample) |
| WO (1) | WO2012033858A2 (enExample) |
| ZA (1) | ZA201301598B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0621279B1 (pt) | 2005-12-30 | 2021-07-20 | Anacor Pharmaceuticals, Inc | Moléculas pequenas contendo boro |
| AP4039A (en) | 2009-08-14 | 2017-02-28 | Daitao Chen | Boron-containing small molecules as antiprotozoal agents |
| WO2011094450A1 (en) | 2010-01-27 | 2011-08-04 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules |
| SMT202100643T1 (it) * | 2010-09-07 | 2022-01-10 | Anacor Pharmaceuticals Inc | Derivati del benzossaborolo per il trattamento delle infezioni batteriche |
| JP6031122B2 (ja) * | 2011-12-22 | 2016-11-24 | ミクウルク ファーマシューティカルズ，インコーポレイテッド | 抗微生物療法のための三環式ホウ素化合物 |
| US11039617B2 (en) | 2013-01-30 | 2021-06-22 | Agrofresh Inc. | Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness |
| US10070649B2 (en) | 2013-01-30 | 2018-09-11 | Agrofresh Inc. | Volatile applications against pathogens |
| US8669207B1 (en) | 2013-01-30 | 2014-03-11 | Dow Agrosciences, Llc. | Compounds and compositions |
| EP2950644B1 (en) | 2013-01-30 | 2017-07-19 | AgroFresh Inc. | Use of benzoxaboroles as volatile antimicrobial agents on meats, plants, or plant parts |
| US9585396B2 (en) | 2013-01-30 | 2017-03-07 | Agrofresh Inc. | Volatile applications against pathogens |
| US9598443B2 (en) | 2013-02-01 | 2017-03-21 | Anacor Pharmaceuticals, Inc. | Boron containing small molecules as antiprotozoal agents |
| KR101636431B1 (ko) | 2013-07-30 | 2016-07-05 | 동아에스티 주식회사 | 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도 |
| WO2015021396A2 (en) * | 2013-08-09 | 2015-02-12 | Glaxosmithkline Intellectual Property (No.2) Limited | Tricyclic benzoxaborole compounds and uses thereof |
| EA038093B1 (ru) * | 2013-12-20 | 2021-07-05 | Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед | Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли |
| ES2732465T3 (es) | 2014-07-01 | 2019-11-22 | Daiichi Sankyo Co Ltd | Benzoxaboroles tricíclicos como agentes antibacterianos |
| MA41495A (fr) | 2015-02-12 | 2017-12-19 | Anacor Pharmaceuticals Inc | Composés benzoxaborole et leurs utilisations |
| EP3426029B1 (en) | 2016-03-07 | 2023-08-30 | AgroFresh Inc. | Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops |
| MA52337A (fr) | 2017-03-01 | 2021-03-03 | Anacor Pharmaceuticals Inc | Nouveaux analogues d'oxaborole et utilisations de ces derniers |
| CA3120976A1 (en) | 2017-11-30 | 2019-06-06 | Boragen, Inc. | Benzoxaborole compounds and formulations thereof |
| CN108727176B (zh) * | 2018-07-26 | 2021-05-18 | 荆楚理工学院 | 一种制备5-卤-2,3-二羟基苯甲醛的方法 |
| MX2021001904A (es) | 2018-08-18 | 2021-05-27 | Boragen Inc | Formas solidas de benzoxaborol sustituido y composiciones de las mismas. |
| AR119515A1 (es) * | 2019-07-30 | 2021-12-22 | Boragen Inc | Proceso de reacción de flujo para la fabricación de agroquímicos que contienen boro |
| CN110664756B (zh) * | 2019-10-09 | 2020-11-17 | 吉林大学 | 一种小儿外伤喷雾剂及其制备方法 |
| US20230340530A1 (en) | 2020-08-31 | 2023-10-26 | Pfizer Inc. | Methods of Protecting RNA |
| JP2025520237A (ja) | 2022-06-23 | 2025-07-03 | ミクウルク ファーマシューティカルズ， インコーポレイテッド | ホウ素化合物を用いて非結核性マイコバクテリア感染症を治療する方法及びその用途、並びに同じ疾患を治療するための医薬組成物 |
| CA3239097A1 (en) * | 2022-06-23 | 2023-12-28 | Shanghai Micurx Pharmaceutical Co., Ltd. | Prodrugs of boron compounds and their use in treating bacterial infections |
| CN115572218B (zh) * | 2022-08-29 | 2024-04-16 | 江阴勒森生物科技有限公司 | 一种2-溴-3-羟基苯甲醛及其相关化学发光底物中间体的制备方法 |
Family Cites Families (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2260336A (en) | 1939-10-16 | 1941-10-28 | Dow Chemical Co | Method of preparation of organic borates |
| US3686398A (en) | 1970-07-20 | 1972-08-22 | Chevron Res | 10,9-boroxarophenanthrene as fungicides |
| GB1396904A (en) | 1972-08-11 | 1975-06-11 | Ici Ltd | Method for the control of micro-organisms |
| US4602011A (en) | 1975-10-24 | 1986-07-22 | Chapman Chemical Company | Antimicrobial compositions and methods of using same |
| US4766113A (en) | 1975-10-24 | 1988-08-23 | Chapman Chemical Company | Antimicrobial compositions and methods of using same |
| US4716035A (en) | 1985-05-24 | 1987-12-29 | The Procter & Gamble Company | Oral compositions and methods for treating gingivitis |
| US5962498A (en) | 1986-06-11 | 1999-10-05 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity |
| US4894220A (en) | 1987-01-30 | 1990-01-16 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition |
| US4919934A (en) | 1989-03-02 | 1990-04-24 | Richardson-Vicks Inc. | Cosmetic sticks |
| US5274792A (en) | 1989-08-19 | 1993-12-28 | Fujitsu Limited | Information processing apparatus with parallel instruction decoding |
| SG47101A1 (en) | 1992-07-31 | 1998-03-20 | Us Bioscience | Crystalline amifostine compositions and methods for the preparation and use of same |
| US5348948A (en) | 1993-05-07 | 1994-09-20 | American Cyanamid Company | 2,2-diaryl-1-(oxa and thia)-2a-azonia-2-borataacenaphthene fungicidal |
| US5348947A (en) | 1993-05-07 | 1994-09-20 | American Cyanamid Company | Diarylboron ester and thioester fungicidal agents |
| US5594151A (en) | 1994-01-28 | 1997-01-14 | Prolinx, Inc. | Phenylboronic acid complexing reagents derived from aminosalicylic acid |
| GB9411587D0 (en) | 1994-06-09 | 1994-08-03 | Zeneca Ltd | Compound, composition and use |
| US6083903A (en) | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
| GB9500856D0 (en) | 1995-01-17 | 1995-03-08 | Zeneca Ltd | Composition and use |
| GB9604926D0 (en) | 1996-03-08 | 1996-05-08 | Sandoz Ltd | Organic compounds |
| WO1997048697A1 (en) | 1996-06-19 | 1997-12-24 | Rhone-Poulenc Rorer Limited | Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase |
| US5831046A (en) | 1996-08-05 | 1998-11-03 | Prolinx, Incorporated | Boronic acid-contaning nucleic acid monomers |
| WO1998012206A1 (en) | 1996-09-19 | 1998-03-26 | The Board Of Trustees Of Leland Stanford Jr. University | Dna adenine methyltransferases and uses thereof |
| EP0947498B1 (en) | 1996-12-02 | 2004-09-15 | Chisso Corporation | Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same |
| US6221640B1 (en) | 1997-05-14 | 2001-04-24 | Cubist Pharmaceuticals, Inc. | Enterococcal aminoacyl-trna synthetase proteins, nucleic acids and strains comprising same |
| DE19829947A1 (de) | 1998-07-04 | 2000-01-05 | Bayer Ag | Elektrolumineszierende Anordnungen mit Bor-Chelaten |
| US6462036B1 (en) | 1998-11-06 | 2002-10-08 | Basf Aktiengesellschaft | Tricyclic pyrazole derivatives |
| TR200102277T2 (tr) | 1998-11-06 | 2002-01-21 | Basf Aktiengesellschaft Ag. | Üç halkalı (Trisiklik) pirazol türevleri |
| WO2000044387A1 (fr) | 1999-01-29 | 2000-08-03 | Nitto Kasei Co., Ltd. | Composes organobores presentant une activite de coccidiostats |
| CN1370170A (zh) | 1999-05-25 | 2002-09-18 | 宾夕法尼亚州研究基金会 | Dna甲基转移酶抑制剂 |
| US6306628B1 (en) | 1999-08-25 | 2001-10-23 | Ambergen, Incorporated | Methods for the detection, analysis and isolation of Nascent proteins |
| CA2383554C (en) | 1999-08-25 | 2008-03-18 | Ambergen, Inc. | Methods for the detection, analysis and isolation of nascent proteins |
| AU7995300A (en) | 1999-10-05 | 2001-05-10 | Bethesda Pharmaceuticals, Inc. | Dithiolane derivatives |
| CO5271678A1 (es) | 2000-01-06 | 2003-04-30 | Marantech Holding Llc | Composiciones para facilitar el crecimiento de la piel y metodos y articulos que las emplean |
| US6521619B2 (en) | 2000-06-29 | 2003-02-18 | Icos Corporation | Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents |
| CA2415938A1 (en) | 2000-07-14 | 2002-01-24 | Zycos Inc. | Alpha-msh related compounds and methods of use |
| JP2004524281A (ja) | 2000-11-30 | 2004-08-12 | ザ ペン ステート リサーチ ファウンデイション | Ｄｎａメチルトランスフェラーゼ阻害剤 |
| DE10110051C2 (de) | 2001-03-02 | 2003-07-03 | Clariant Gmbh | Verfahren zur Herstellung von Boron- und Borinsäuren |
| US20030051728A1 (en) | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
| JP2005503425A (ja) | 2001-05-24 | 2005-02-03 | アレックザ モレキュラー デリヴァリー コーポレイション | 所定の吸入ルートによる薬剤エステルの送出 |
| GB0117645D0 (en) | 2001-07-19 | 2001-09-12 | Isis Innovation | Therapeutic stratergies for prevention and treatment of alzheimers disease |
| DE10143979A1 (de) | 2001-09-07 | 2003-03-27 | Clariant Gmbh | Verfahren zur Herstellung von Bisallylboranen und nicht-aromatischen Boronsäuren |
| WO2003033002A1 (en) | 2001-10-11 | 2003-04-24 | Ono Pharmaceutical Co | Intracellular calcium concentration increase inhibitors |
| CA2473238A1 (en) | 2002-01-10 | 2003-07-24 | The Penn State Research Foundation | Methods for the preparation of alkyl diaryl borinates and complexed diarylboronic acids |
| JP2006507352A (ja) | 2002-07-09 | 2006-03-02 | ポイント セラピューティクス， インコーポレイテッド | イソロイシンのボロプロリン化合物に関する方法および組成物 |
| ES2283867T3 (es) | 2002-12-02 | 2007-11-01 | Solvias Ag | Hidrogenacion catalitica de dobles enlaces de carbonoheteroatomo. |
| US7390806B2 (en) | 2002-12-18 | 2008-06-24 | Anacor Pharmaceuticals, Inc. | Antibiotics containing borinic acid complexes and methods of use |
| CA2509645A1 (en) | 2002-12-18 | 2004-07-08 | Anacor Pharmaceuticals, Inc. | Antibiotics containing borinic acid complexes and methods of use |
| US20050125852A1 (en) | 2003-05-09 | 2005-06-09 | Sugen, Inc. | Novel kinases |
| WO2005013892A2 (en) | 2003-06-16 | 2005-02-17 | Anacor Pharmaceuticals, Inc. | Hydrolytically-resistant boron-containing therapeutics and methods of use |
| DK1755661T3 (da) | 2004-05-12 | 2014-06-16 | Brigham & Womens Hospital | Gelsolin til anvendelse til behandling af infektioner |
| AR049915A1 (es) | 2004-06-14 | 2006-09-13 | Anacor Pharmaceuticals Inc | Compuestos con contenido de boro y metodos de uso de los mismos |
| WO2006062731A1 (en) | 2004-11-19 | 2006-06-15 | University Of North Texas Health Science Center At Fort Worth | Phenanthroline and derivatives thereof used to lower intraocular pressure in an affected eye |
| GB0501944D0 (en) | 2005-01-31 | 2005-03-09 | Univ Cambridge Tech | Compounds for use in chemical detection and/or quantitation |
| AU2006214247C1 (en) | 2005-02-16 | 2012-11-08 | Anacor Pharmaceuticals, Llc | Boron-containing small molecules |
| WO2006096131A1 (en) | 2005-03-08 | 2006-09-14 | Agency For Science, Technology And Research | Chiral bisoxazoline catalysts |
| US20060222671A1 (en) | 2005-03-30 | 2006-10-05 | Astion Development A/S | Dermatological compositions and salts for the treatment of dermatological diseases |
| WO2007022437A2 (en) | 2005-08-18 | 2007-02-22 | Auspex Pharmaceuticals, Inc. | Therapeutic agents for the treatment of cancer and metabolic disorders |
| BRPI0621279B1 (pt) | 2005-12-30 | 2021-07-20 | Anacor Pharmaceuticals, Inc | Moléculas pequenas contendo boro |
| CA2642583C (en) * | 2006-02-16 | 2016-08-23 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as anti-inflammatory agents |
| WO2007131072A2 (en) * | 2006-05-02 | 2007-11-15 | Anacor Pharmaceuticals, Inc. | Hydrolytically-resistant boron-containing therapeutics and methods of use |
| US20070286822A1 (en) | 2006-06-12 | 2007-12-13 | Anacor Pharmaceuticals Inc. | Compounds for the Treatment of Periodontal Disease |
| WO2007146965A2 (en) | 2006-06-12 | 2007-12-21 | Anacor Pharmaceuticals, Inc. | Compounds for the treatment of periodontal disease |
| KR100848491B1 (ko) | 2007-01-16 | 2008-07-28 | 영진약품공업주식회사 | 베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법 |
| JO3396B1 (ar) * | 2007-06-20 | 2019-10-20 | Anacor Pharmaceuticals Inc | جزيئات صغيرة تحتوي على البورون |
| EP2187893A4 (en) | 2008-03-06 | 2012-02-22 | Anacor Pharmaceuticals Inc | SMALL BORON-CONTAINING MOLECULES AS ANTI-INFLAMMATORY AGENTS |
| CN102014927A (zh) | 2008-03-06 | 2011-04-13 | 安纳考尔医药公司 | 作为抗炎药的含硼的小分子 |
| EP2285384A4 (en) | 2008-05-12 | 2012-04-25 | Anacor Pharmaceuticals Inc | BORN SMALL MOLECULES |
| WO2010028005A1 (en) | 2008-09-04 | 2010-03-11 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| WO2010045505A1 (en) | 2008-10-15 | 2010-04-22 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules as anti-protozoal agents |
| US9493489B2 (en) | 2008-10-15 | 2016-11-15 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as anti-protozoal agents |
| AU2009335744A1 (en) | 2008-12-17 | 2010-07-15 | Anacor Pharmaceuticals, Inc. | Polymorphs of (S)-3-aminomethyl-7-(3-hydroxy-propoxy) -3H-benzo[c][1,2] oxaborol-1-ol |
| JP2013500974A (ja) | 2009-07-28 | 2013-01-10 | アナコール ファーマシューティカルズ，インコーポレイテッド | 三置換ホウ素含有分子 |
| SMT202100643T1 (it) | 2010-09-07 | 2022-01-10 | Anacor Pharmaceuticals Inc | Derivati del benzossaborolo per il trattamento delle infezioni batteriche |
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2011
- 2011-09-07 SM SM20210643T patent/SMT202100643T1/it unknown
- 2011-09-07 AU AU2011299243A patent/AU2011299243C1/en active Active
- 2011-09-07 HR HRP20211762TT patent/HRP20211762T1/hr unknown
- 2011-09-07 PT PT171766546T patent/PT3251678T/pt unknown
- 2011-09-07 US US13/227,444 patent/US8703742B2/en active Active
- 2011-09-07 DK DK17176654.6T patent/DK3251678T3/da active
- 2011-09-07 SG SG2013014493A patent/SG187969A1/en unknown
- 2011-09-07 CN CN2011800427618A patent/CN103140228A/zh active Pending
- 2011-09-07 EP EP17176654.6A patent/EP3251678B1/en active Active
- 2011-09-07 WO PCT/US2011/050728 patent/WO2012033858A2/en not_active Ceased
- 2011-09-07 BR BR112013005426-3A patent/BR112013005426B1/pt active IP Right Grant
- 2011-09-07 KR KR1020137005717A patent/KR101949423B1/ko active Active
- 2011-09-07 SI SI201132017T patent/SI3251678T1/sl unknown
- 2011-09-07 KR KR1020197003860A patent/KR102152901B1/ko active Active
- 2011-09-07 DK DK11758050.6T patent/DK2613788T3/en active
- 2011-09-07 CN CN201810051113.2A patent/CN108610356B/zh active Active
- 2011-09-07 ES ES11758050.6T patent/ES2635333T3/es active Active
- 2011-09-07 PL PL17176654T patent/PL3251678T3/pl unknown
- 2011-09-07 RS RS20211391A patent/RS62548B1/sr unknown
- 2011-09-07 CA CA2810021A patent/CA2810021C/en active Active
- 2011-09-07 LT LTEP17176654.6T patent/LT3251678T/lt unknown
- 2011-09-07 ES ES17176654T patent/ES2898695T3/es active Active
- 2011-09-07 EP EP11758050.6A patent/EP2613788B1/en active Active
- 2011-09-07 SG SG10201507032YA patent/SG10201507032YA/en unknown
- 2011-09-07 EA EA201791850A patent/EA033311B1/ru unknown
- 2011-09-07 JP JP2013527375A patent/JP5952280B2/ja active Active
- 2011-09-07 HU HUE17176654A patent/HUE059033T2/hu unknown
- 2011-09-07 EA EA201390274A patent/EA028743B1/ru not_active IP Right Cessation
- 2011-09-07 MX MX2013002651A patent/MX338209B/es active IP Right Grant
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2013
- 2013-02-28 IL IL225000A patent/IL225000A/en active IP Right Grant
- 2013-03-01 ZA ZA2013/01598A patent/ZA201301598B/en unknown
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2014
- 2014-03-21 US US14/221,637 patent/US9751898B2/en active Active
-
2016
- 2016-03-13 IL IL244556A patent/IL244556B/en active IP Right Grant
- 2016-06-09 JP JP2016114971A patent/JP2016199558A/ja not_active Withdrawn
-
2017
- 2017-08-24 US US15/685,846 patent/US20170355719A1/en not_active Abandoned
- 2017-10-06 JP JP2017195759A patent/JP6491294B2/ja active Active
-
2019
- 2019-02-28 JP JP2019035145A patent/JP2019112431A/ja active Pending
- 2019-07-30 US US16/526,248 patent/US11008345B2/en active Active
-
2021
- 2021-11-16 CY CY20211100990T patent/CY1124728T1/el unknown
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