MA32406B1 - Composés contenant de l'azote tricyclique et utilisation de ceux-ci comme antibactériens - Google Patents

Composés contenant de l'azote tricyclique et utilisation de ceux-ci comme antibactériens

Info

Publication number
MA32406B1
MA32406B1 MA33446A MA33446A MA32406B1 MA 32406 B1 MA32406 B1 MA 32406B1 MA 33446 A MA33446 A MA 33446A MA 33446 A MA33446 A MA 33446A MA 32406 B1 MA32406 B1 MA 32406B1
Authority
MA
Morocco
Prior art keywords
azotes
antibacterials
compounds containing
containing tricyclic
formula
Prior art date
Application number
MA33446A
Other languages
Arabic (ar)
English (en)
Inventor
Carlos Alemparte-Gallardo
Christopher Barfoot
David Barros-Aguirre
Monica Cacho-Izquierdo
Roman Jose Maria Fiandor
Alan Joseph Hennessy
Neil David Pearson
Modesto Jesus Remuinan-Blanco
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MA32406B1 publication Critical patent/MA32406B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention concerne des composés représentés par la formule (i) ou des sels ou des oxydes de n pharmaceutiquement acceptables, la formule (i) (formule chimique représentée), des compositions pharmaceutiques comprenant ces composés, leur utilisation thérapeutique, en particulier contre la tuberculose, et des procédés de préparation de celle-ci.
MA33446A 2008-05-23 2010-12-20 Composés contenant de l'azote tricyclique et utilisation de ceux-ci comme antibactériens MA32406B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08382018 2008-05-23
EP08382057 2008-10-17
EP08382044 2008-10-17
PCT/EP2009/056177 WO2009141398A1 (fr) 2008-05-23 2009-05-20 Composés contenant de l'azote tricyclique et utilisation de ceux-ci comme antibactériens

Publications (1)

Publication Number Publication Date
MA32406B1 true MA32406B1 (fr) 2011-06-01

Family

ID=40874958

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33446A MA32406B1 (fr) 2008-05-23 2010-12-20 Composés contenant de l'azote tricyclique et utilisation de ceux-ci comme antibactériens

Country Status (24)

Country Link
US (1) US8097628B2 (fr)
EP (1) EP2300476B1 (fr)
JP (1) JP5474941B2 (fr)
KR (1) KR20110016947A (fr)
CN (1) CN102105473B (fr)
AR (1) AR071869A1 (fr)
AU (1) AU2009248786B2 (fr)
BR (1) BRPI0912995A2 (fr)
CA (1) CA2725726A1 (fr)
CL (1) CL2009001267A1 (fr)
CO (1) CO6321284A2 (fr)
CR (1) CR11838A (fr)
DO (1) DOP2010000342A (fr)
EA (1) EA018817B1 (fr)
ES (1) ES2455496T3 (fr)
IL (1) IL209270A (fr)
MA (1) MA32406B1 (fr)
MX (1) MX2010012732A (fr)
NZ (1) NZ589062A (fr)
PE (1) PE20091927A1 (fr)
TW (1) TW201008941A (fr)
UY (1) UY31839A (fr)
WO (1) WO2009141398A1 (fr)
ZA (1) ZA201007945B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009248774B2 (en) 2008-05-23 2012-05-31 Novartis Ag Derivatives of quinolines and quinoxalines as protein tyrosine kinase inhibitors
WO2010043714A1 (fr) 2008-10-17 2010-04-22 Glaxo Group Limited Composés azotés tricycliques utilisés comme agents antibactériens
AU2011248194B2 (en) 2010-05-04 2015-06-04 Alkermes Pharma Ireland Limited Process for synthesizing oxidized lactam compounds
CA2871270A1 (fr) 2012-05-02 2013-11-07 Lupin Limited Composes substitues de pyridine en tant que modulateurs de crac
CN103113291B (zh) * 2013-02-04 2015-03-04 浙江大学 一种3位烯基吡啶衍生物的合成方法
MX2017002321A (es) * 2014-08-22 2017-08-02 Glaxosmithkline Ip Dev Ltd Compuestos que contienen nitrogeno triciclico para tratar infeccion por neisseria gonorrhoeae.
BR112018075297A2 (pt) 2016-06-08 2019-03-19 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A composto, composição farmacêutica, e, método para tratar uma infecção bacteriana
WO2021198981A1 (fr) 2020-04-01 2021-10-07 Janssen Biopharma, Inc. Composés antiviraux et leurs utilisations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1963324B1 (fr) * 2005-12-22 2010-04-21 Glaxo Group Limited Composes heterocycliques, leur synthese et leur utilisation en tant qu'antibacteriens
ATE481406T1 (de) * 2006-04-06 2010-10-15 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
DK2137196T3 (da) * 2007-04-20 2011-01-10 Glaxo Group Ltd Tricykliske nitrogenholdige forbindelser som antibakterielle midler
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
NZ589062A (en) 2012-06-29
ZA201007945B (en) 2011-08-31
TW201008941A (en) 2010-03-01
EP2300476A1 (fr) 2011-03-30
CL2009001267A1 (es) 2010-12-31
AR071869A1 (es) 2010-07-21
PE20091927A1 (es) 2010-01-21
UY31839A (es) 2009-12-14
IL209270A0 (en) 2011-01-31
EA018817B1 (ru) 2013-10-30
MX2010012732A (es) 2010-12-07
CN102105473A (zh) 2011-06-22
BRPI0912995A2 (pt) 2015-10-13
CN102105473B (zh) 2013-05-08
DOP2010000342A (es) 2010-11-30
IL209270A (en) 2013-09-30
KR20110016947A (ko) 2011-02-18
AU2009248786A1 (en) 2009-11-26
CA2725726A1 (fr) 2009-11-26
JP5474941B2 (ja) 2014-04-16
EP2300476B1 (fr) 2014-01-08
US8097628B2 (en) 2012-01-17
EA201071352A1 (ru) 2011-06-30
WO2009141398A1 (fr) 2009-11-26
CO6321284A2 (es) 2011-09-20
JP2011520943A (ja) 2011-07-21
ES2455496T3 (es) 2014-04-15
CR11838A (es) 2011-03-25
US20090306089A1 (en) 2009-12-10
AU2009248786B2 (en) 2013-04-04

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