CY1124728T1 - Παραγωγα βενζοξαβορολης για τη θεραπεια βακτηριακων λοιμωξεων - Google Patents
Παραγωγα βενζοξαβορολης για τη θεραπεια βακτηριακων λοιμωξεωνInfo
- Publication number
- CY1124728T1 CY1124728T1 CY20211100990T CY211100990T CY1124728T1 CY 1124728 T1 CY1124728 T1 CY 1124728T1 CY 20211100990 T CY20211100990 T CY 20211100990T CY 211100990 T CY211100990 T CY 211100990T CY 1124728 T1 CY1124728 T1 CY 1124728T1
- Authority
- CY
- Cyprus
- Prior art keywords
- unsubstituted
- treatment
- bacterial infections
- substituted
- benzoxaborole
- Prior art date
Links
- GDMJXXLVTYSBBE-UHFFFAOYSA-N 1,2-benzoxaborole Chemical class C1=CC=C2OB=CC2=C1 GDMJXXLVTYSBBE-UHFFFAOYSA-N 0.000 title abstract 2
- 208000035143 Bacterial infection Diseases 0.000 title abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004971 nitroalkyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38059610P | 2010-09-07 | 2010-09-07 | |
| EP11758050.6A EP2613788B1 (en) | 2010-09-07 | 2011-09-07 | Benzoxaborole derivatives for treating bacterial infections |
| PCT/US2011/050728 WO2012033858A2 (en) | 2010-09-07 | 2011-09-07 | Boron-containing small molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1124728T1 true CY1124728T1 (el) | 2022-07-22 |
Family
ID=44653589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20211100990T CY1124728T1 (el) | 2010-09-07 | 2021-11-16 | Παραγωγα βενζοξαβορολης για τη θεραπεια βακτηριακων λοιμωξεων |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US8703742B2 (enExample) |
| EP (2) | EP3251678B1 (enExample) |
| JP (4) | JP5952280B2 (enExample) |
| KR (2) | KR101949423B1 (enExample) |
| CN (2) | CN103140228A (enExample) |
| AU (1) | AU2011299243C1 (enExample) |
| BR (1) | BR112013005426B1 (enExample) |
| CA (1) | CA2810021C (enExample) |
| CY (1) | CY1124728T1 (enExample) |
| DK (2) | DK3251678T3 (enExample) |
| EA (2) | EA033311B1 (enExample) |
| ES (2) | ES2635333T3 (enExample) |
| HR (1) | HRP20211762T1 (enExample) |
| HU (1) | HUE059033T2 (enExample) |
| IL (2) | IL225000A (enExample) |
| LT (1) | LT3251678T (enExample) |
| MX (1) | MX338209B (enExample) |
| PL (1) | PL3251678T3 (enExample) |
| PT (1) | PT3251678T (enExample) |
| RS (1) | RS62548B1 (enExample) |
| SG (2) | SG187969A1 (enExample) |
| SI (1) | SI3251678T1 (enExample) |
| SM (1) | SMT202100643T1 (enExample) |
| WO (1) | WO2012033858A2 (enExample) |
| ZA (1) | ZA201301598B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0621279B1 (pt) | 2005-12-30 | 2021-07-20 | Anacor Pharmaceuticals, Inc | Moléculas pequenas contendo boro |
| AP4039A (en) | 2009-08-14 | 2017-02-28 | Daitao Chen | Boron-containing small molecules as antiprotozoal agents |
| WO2011094450A1 (en) | 2010-01-27 | 2011-08-04 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules |
| SMT202100643T1 (it) * | 2010-09-07 | 2022-01-10 | Anacor Pharmaceuticals Inc | Derivati del benzossaborolo per il trattamento delle infezioni batteriche |
| JP6031122B2 (ja) * | 2011-12-22 | 2016-11-24 | ミクウルク ファーマシューティカルズ，インコーポレイテッド | 抗微生物療法のための三環式ホウ素化合物 |
| US11039617B2 (en) | 2013-01-30 | 2021-06-22 | Agrofresh Inc. | Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness |
| US10070649B2 (en) | 2013-01-30 | 2018-09-11 | Agrofresh Inc. | Volatile applications against pathogens |
| US8669207B1 (en) | 2013-01-30 | 2014-03-11 | Dow Agrosciences, Llc. | Compounds and compositions |
| EP2950644B1 (en) | 2013-01-30 | 2017-07-19 | AgroFresh Inc. | Use of benzoxaboroles as volatile antimicrobial agents on meats, plants, or plant parts |
| US9585396B2 (en) | 2013-01-30 | 2017-03-07 | Agrofresh Inc. | Volatile applications against pathogens |
| US9598443B2 (en) | 2013-02-01 | 2017-03-21 | Anacor Pharmaceuticals, Inc. | Boron containing small molecules as antiprotozoal agents |
| KR101636431B1 (ko) | 2013-07-30 | 2016-07-05 | 동아에스티 주식회사 | 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도 |
| WO2015021396A2 (en) * | 2013-08-09 | 2015-02-12 | Glaxosmithkline Intellectual Property (No.2) Limited | Tricyclic benzoxaborole compounds and uses thereof |
| EA038093B1 (ru) * | 2013-12-20 | 2021-07-05 | Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед | Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли |
| ES2732465T3 (es) | 2014-07-01 | 2019-11-22 | Daiichi Sankyo Co Ltd | Benzoxaboroles tricíclicos como agentes antibacterianos |
| MA41495A (fr) | 2015-02-12 | 2017-12-19 | Anacor Pharmaceuticals Inc | Composés benzoxaborole et leurs utilisations |
| EP3426029B1 (en) | 2016-03-07 | 2023-08-30 | AgroFresh Inc. | Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops |
| MA52337A (fr) | 2017-03-01 | 2021-03-03 | Anacor Pharmaceuticals Inc | Nouveaux analogues d'oxaborole et utilisations de ces derniers |
| CA3120976A1 (en) | 2017-11-30 | 2019-06-06 | Boragen, Inc. | Benzoxaborole compounds and formulations thereof |
| CN108727176B (zh) * | 2018-07-26 | 2021-05-18 | 荆楚理工学院 | 一种制备5-卤-2,3-二羟基苯甲醛的方法 |
| MX2021001904A (es) | 2018-08-18 | 2021-05-27 | Boragen Inc | Formas solidas de benzoxaborol sustituido y composiciones de las mismas. |
| AR119515A1 (es) * | 2019-07-30 | 2021-12-22 | Boragen Inc | Proceso de reacción de flujo para la fabricación de agroquímicos que contienen boro |
| CN110664756B (zh) * | 2019-10-09 | 2020-11-17 | 吉林大学 | 一种小儿外伤喷雾剂及其制备方法 |
| US20230340530A1 (en) | 2020-08-31 | 2023-10-26 | Pfizer Inc. | Methods of Protecting RNA |
| JP2025520237A (ja) | 2022-06-23 | 2025-07-03 | ミクウルク ファーマシューティカルズ， インコーポレイテッド | ホウ素化合物を用いて非結核性マイコバクテリア感染症を治療する方法及びその用途、並びに同じ疾患を治療するための医薬組成物 |
| CA3239097A1 (en) * | 2022-06-23 | 2023-12-28 | Shanghai Micurx Pharmaceutical Co., Ltd. | Prodrugs of boron compounds and their use in treating bacterial infections |
| CN115572218B (zh) * | 2022-08-29 | 2024-04-16 | 江阴勒森生物科技有限公司 | 一种2-溴-3-羟基苯甲醛及其相关化学发光底物中间体的制备方法 |
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-
2011
- 2011-09-07 SM SM20210643T patent/SMT202100643T1/it unknown
- 2011-09-07 AU AU2011299243A patent/AU2011299243C1/en active Active
- 2011-09-07 HR HRP20211762TT patent/HRP20211762T1/hr unknown
- 2011-09-07 PT PT171766546T patent/PT3251678T/pt unknown
- 2011-09-07 US US13/227,444 patent/US8703742B2/en active Active
- 2011-09-07 DK DK17176654.6T patent/DK3251678T3/da active
- 2011-09-07 SG SG2013014493A patent/SG187969A1/en unknown
- 2011-09-07 CN CN2011800427618A patent/CN103140228A/zh active Pending
- 2011-09-07 EP EP17176654.6A patent/EP3251678B1/en active Active
- 2011-09-07 WO PCT/US2011/050728 patent/WO2012033858A2/en not_active Ceased
- 2011-09-07 BR BR112013005426-3A patent/BR112013005426B1/pt active IP Right Grant
- 2011-09-07 KR KR1020137005717A patent/KR101949423B1/ko active Active
- 2011-09-07 SI SI201132017T patent/SI3251678T1/sl unknown
- 2011-09-07 KR KR1020197003860A patent/KR102152901B1/ko active Active
- 2011-09-07 DK DK11758050.6T patent/DK2613788T3/en active
- 2011-09-07 CN CN201810051113.2A patent/CN108610356B/zh active Active
- 2011-09-07 ES ES11758050.6T patent/ES2635333T3/es active Active
- 2011-09-07 PL PL17176654T patent/PL3251678T3/pl unknown
- 2011-09-07 RS RS20211391A patent/RS62548B1/sr unknown
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2013
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2014
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2016
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2017
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2019
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2021
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