HRP20200701T1 - Postupak za stvaranje pluripotentne matične stanice inducirane od mezenhimalne matične stanice i inducirana pluripotentna matična stanica stvorena postupkom - Google Patents

Postupak za stvaranje pluripotentne matične stanice inducirane od mezenhimalne matične stanice i inducirana pluripotentna matična stanica stvorena postupkom Download PDF

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Publication number
HRP20200701T1
HRP20200701T1 HRP20200701TT HRP20200701T HRP20200701T1 HR P20200701 T1 HRP20200701 T1 HR P20200701T1 HR P20200701T T HRP20200701T T HR P20200701TT HR P20200701 T HRP20200701 T HR P20200701T HR P20200701 T1 HRP20200701 T1 HR P20200701T1
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HR
Croatia
Prior art keywords
medium
stem cell
induced pluripotent
pluripotent stem
aminomax
Prior art date
Application number
HRP20200701TT
Other languages
English (en)
Inventor
Sang Yeon Lee
Won Ju Jung
Ho Bin Kim
Min Sun Oh
Kye Ho Lee
Original Assignee
Bbhc Co. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bbhc Co. Ltd. filed Critical Bbhc Co. Ltd.
Publication of HRP20200701T1 publication Critical patent/HRP20200701T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/76—Undefined extracts from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1369—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from blood-borne mesenchymal stem cells, e.g. MSC from umbilical blood

Claims (4)

1. Postupak za stvaranje inducirane pluripotentne matične stanice, postupak sadrži: dodavanje ekstrakta Ecklonia cava mediju stanične kulture; i dediferenciranje mezenhimske matične stanice u induciranu pluripotentnu matičnu stanicu u mediju.
2. Postupak prema zahtjevu 1, naznačen time što medij stanične kulture sadrži Dulbeccov modificirani Eagle medij (DMEM), minimalni esencijalni medij (MEM), bazni Eagle medij (BME), RPMI 1640, F-10, F-12, DMEM-F12, α-minimalni esencijalni medij (a-MEM), Glasgowov minimalni esencijalni medij (GMEM), Iscove modificirani Dulbeccov medij (IMDM), Mac-Coyev 5A medij, AMINOMAX kompletni medij, AMINOMAX II kompletni medij, CHANGov medij i MESEMCULT-XF medij.
3. Postupak prema bilo kojem od zahtjeva 1 ili 2, naznačen time što se ekstrakt Ecklonia cava nalazi u mediju u količini od 100 do 400mg/mL u odnosu na sastav medija.
4. Postupak prema bilo kojem od zahtjeva 1 do 3, naznačen time što medij nadalje sadrži 0.01 do 10 v/v% energetske vode, pri čemu se energetska voda sastoji od pročišćene deionizirane vode koja sadrži SiO2, Al2O3, TiO3, Fe2O3, CaO, Na2O, K2O i LiO.
HRP20200701TT 2013-11-01 2020-04-30 Postupak za stvaranje pluripotentne matične stanice inducirane od mezenhimalne matične stanice i inducirana pluripotentna matična stanica stvorena postupkom HRP20200701T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13896647.8A EP3064572B1 (en) 2013-11-01 2013-11-01 Method for producing induced pluripotent stem cell from mesenchymal stem cell and induced pluripotent stem cell produced by the method
PCT/KR2013/009845 WO2015064795A1 (ko) 2013-11-01 2013-11-01 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하는 방법 및 그 방법에 의해 제조된 유도만능 줄기세포

Publications (1)

Publication Number Publication Date
HRP20200701T1 true HRP20200701T1 (hr) 2020-12-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20200701TT HRP20200701T1 (hr) 2013-11-01 2020-04-30 Postupak za stvaranje pluripotentne matične stanice inducirane od mezenhimalne matične stanice i inducirana pluripotentna matična stanica stvorena postupkom

Country Status (16)

Country Link
US (1) US9938504B2 (hr)
EP (1) EP3064572B1 (hr)
JP (1) JP6700175B2 (hr)
CN (1) CN105264066B (hr)
CY (1) CY1123057T1 (hr)
DK (1) DK3064572T3 (hr)
ES (1) ES2790669T3 (hr)
HR (1) HRP20200701T1 (hr)
HU (1) HUE049567T2 (hr)
LT (1) LT3064572T (hr)
PL (1) PL3064572T3 (hr)
PT (1) PT3064572T (hr)
RS (1) RS60200B1 (hr)
SG (1) SG11201508796SA (hr)
SI (1) SI3064572T1 (hr)
WO (1) WO2015064795A1 (hr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101592401B1 (ko) * 2014-06-13 2016-02-05 주식회사 비비에이치씨 지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하는 방법 및 그 방법에 의해 제조된 유도만능 줄기세포

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KR101542849B1 (ko) 2013-11-01 2015-08-10 주식회사 비비에이치씨 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 간세포로 분화시키는 방법
KR101542848B1 (ko) 2013-11-01 2015-08-10 주식회사 비비에이치씨 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 골아세포로 분화시키는 방법
KR101542850B1 (ko) 2013-11-01 2015-08-10 주식회사 비비에이치씨 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 지방세포로 분화시키는 방법
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KR101592401B1 (ko) 2014-06-13 2016-02-05 주식회사 비비에이치씨 지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하는 방법 및 그 방법에 의해 제조된 유도만능 줄기세포

Also Published As

Publication number Publication date
CN105264066B (zh) 2021-06-11
SG11201508796SA (en) 2015-11-27
CN105264066A (zh) 2016-01-20
EP3064572B1 (en) 2020-02-12
US9938504B2 (en) 2018-04-10
JP2016521990A (ja) 2016-07-28
HUE049567T2 (hu) 2020-10-28
US20160230146A1 (en) 2016-08-11
ES2790669T3 (es) 2020-10-28
EP3064572A4 (en) 2017-03-22
LT3064572T (lt) 2020-07-27
RS60200B1 (sr) 2020-06-30
PT3064572T (pt) 2020-05-07
WO2015064795A1 (ko) 2015-05-07
PL3064572T3 (pl) 2020-07-13
SI3064572T1 (sl) 2020-08-31
DK3064572T3 (da) 2020-05-04
JP6700175B2 (ja) 2020-05-27
CY1123057T1 (el) 2021-10-29
EP3064572A1 (en) 2016-09-07

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