HRP20180054T1 - Farmaceutski pripravci koji sadrže toksoide clostridium difficile a i b - Google Patents

Farmaceutski pripravci koji sadrže toksoide clostridium difficile a i b Download PDF

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Publication number
HRP20180054T1
HRP20180054T1 HRP20180054TT HRP20180054T HRP20180054T1 HR P20180054 T1 HRP20180054 T1 HR P20180054T1 HR P20180054T T HRP20180054T T HR P20180054TT HR P20180054 T HRP20180054 T HR P20180054T HR P20180054 T1 HRP20180054 T1 HR P20180054T1
Authority
HR
Croatia
Prior art keywords
preparation
sodium
clostridium difficile
toxoid
sucrose
Prior art date
Application number
HRP20180054TT
Other languages
English (en)
Croatian (hr)
Inventor
C. Russell Middaugh
Richard Fahrner
Peter Ciarametaro
Original Assignee
Sanofi Pasteur Biologics, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Biologics, Llc filed Critical Sanofi Pasteur Biologics, Llc
Publication of HRP20180054T1 publication Critical patent/HRP20180054T1/hr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/08Clostridium, e.g. Clostridium tetani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
HRP20180054TT 2007-09-14 2008-09-15 Farmaceutski pripravci koji sadrže toksoide clostridium difficile a i b HRP20180054T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97249607P 2007-09-14 2007-09-14
EP08830210.4A EP2198007B1 (en) 2007-09-14 2008-09-15 Pharmaceutical compositions containing clostridium difficile toxoids a and b
PCT/US2008/010767 WO2009035707A1 (en) 2007-09-14 2008-09-15 Pharmaceutical compositions containing clostridium difficile toxoids a and b

Publications (1)

Publication Number Publication Date
HRP20180054T1 true HRP20180054T1 (hr) 2018-02-09

Family

ID=40452372

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20180054TT HRP20180054T1 (hr) 2007-09-14 2008-09-15 Farmaceutski pripravci koji sadrže toksoide clostridium difficile a i b

Country Status (21)

Country Link
US (3) US9320790B2 (https=)
EP (3) EP2198007B1 (https=)
JP (3) JP5503543B2 (https=)
KR (2) KR20160005378A (https=)
CN (2) CN106039299A (https=)
AU (1) AU2008299885C1 (https=)
BR (1) BRPI0816790A8 (https=)
CA (1) CA2699435A1 (https=)
CY (1) CY1119979T1 (https=)
DK (1) DK2198007T3 (https=)
ES (2) ES2657485T3 (https=)
HR (1) HRP20180054T1 (https=)
HU (1) HUE037932T2 (https=)
IL (1) IL204366A (https=)
MX (1) MX2010002815A (https=)
NO (1) NO2198007T3 (https=)
PL (1) PL2198007T3 (https=)
PT (1) PT2198007T (https=)
RU (1) RU2550271C2 (https=)
SI (1) SI2198007T1 (https=)
WO (1) WO2009035707A1 (https=)

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Also Published As

Publication number Publication date
MX2010002815A (es) 2010-07-30
CA2699435A1 (en) 2009-03-19
DK2198007T3 (en) 2018-01-15
EP3124044B1 (en) 2024-12-18
IL204366A (en) 2013-02-28
PL2198007T3 (pl) 2018-03-30
AU2008299885A1 (en) 2009-03-19
BRPI0816790A2 (pt) 2014-10-14
KR20160005378A (ko) 2016-01-14
AU2008299885C1 (en) 2015-06-25
EP2198007A1 (en) 2010-06-23
CY1119979T1 (el) 2018-12-12
EP2198007B1 (en) 2017-10-25
EP2198007A4 (en) 2012-03-07
SI2198007T1 (en) 2018-04-30
US20160317640A1 (en) 2016-11-03
NO2198007T3 (https=) 2018-03-24
CN101855336B (zh) 2019-07-30
JP2010539172A (ja) 2010-12-16
KR101679812B1 (ko) 2016-11-28
US9687541B2 (en) 2017-06-27
ES3001561T3 (en) 2025-03-05
EP4537849A2 (en) 2025-04-16
CN106039299A (zh) 2016-10-26
JP6258674B2 (ja) 2018-01-10
RU2550271C2 (ru) 2015-05-10
BRPI0816790A8 (pt) 2017-05-16
JP2017052773A (ja) 2017-03-16
RU2010114730A (ru) 2011-10-20
WO2009035707A1 (en) 2009-03-19
EP3124044B8 (en) 2025-01-22
EP3124044C0 (en) 2024-12-18
JP2014055174A (ja) 2014-03-27
HUE037932T2 (hu) 2018-09-28
AU2008299885B2 (en) 2014-12-11
EP4537849A3 (en) 2025-07-09
US9320790B2 (en) 2016-04-26
JP5503543B2 (ja) 2014-05-28
US20180000920A1 (en) 2018-01-04
ES2657485T3 (es) 2018-03-05
CN101855336A (zh) 2010-10-06
US20110045025A1 (en) 2011-02-24
PT2198007T (pt) 2018-01-29
EP3124044A1 (en) 2017-02-01
WO2009035707A9 (en) 2010-06-10
KR20100075912A (ko) 2010-07-05
US10639362B2 (en) 2020-05-05

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