HRP20170416T1 - Sintetski postupci i postupci pročišćavanja spojeva fosfaplatine i njihova uporaba - Google Patents

Sintetski postupci i postupci pročišćavanja spojeva fosfaplatine i njihova uporaba Download PDF

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Publication number
HRP20170416T1
HRP20170416T1 HRP20170416TT HRP20170416T HRP20170416T1 HR P20170416 T1 HRP20170416 T1 HR P20170416T1 HR P20170416T T HRP20170416T T HR P20170416TT HR P20170416 T HRP20170416 T HR P20170416T HR P20170416 T1 HRP20170416 T1 HR P20170416T1
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HR
Croatia
Prior art keywords
platinum
reaction mixture
pyrophosphate
substituted
monomer complex
Prior art date
Application number
HRP20170416TT
Other languages
English (en)
Croatian (hr)
Inventor
Wayne D. Luke
Steffen Jost
Original Assignee
Phosplatin Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phosplatin Therapeutics Llc filed Critical Phosplatin Therapeutics Llc
Publication of HRP20170416T1 publication Critical patent/HRP20170416T1/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HRP20170416TT 2012-05-24 2013-03-15 Sintetski postupci i postupci pročišćavanja spojeva fosfaplatine i njihova uporaba HRP20170416T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261651200P 2012-05-24 2012-05-24
PCT/US2013/031885 WO2013176764A1 (en) 2012-05-24 2013-03-15 Synthetic and purification methods for phosphaplatin compounds and uses thereof
EP13793812.2A EP2855496B1 (en) 2012-05-24 2013-03-15 Synthetic and purification methods for phosphaplatin compounds and uses thereof

Publications (1)

Publication Number Publication Date
HRP20170416T1 true HRP20170416T1 (hr) 2017-05-19

Family

ID=49624225

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20170416TT HRP20170416T1 (hr) 2012-05-24 2013-03-15 Sintetski postupci i postupci pročišćavanja spojeva fosfaplatine i njihova uporaba
HRP20191904TT HRP20191904T1 (hr) 2012-05-24 2019-10-21 Postupak pročišćavanja spojeva fosfaplatine

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20191904TT HRP20191904T1 (hr) 2012-05-24 2019-10-21 Postupak pročišćavanja spojeva fosfaplatine

Country Status (18)

Country Link
US (2) US8846964B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP3202769B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP5833795B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (2) CN106967124B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CY (2) CY1118746T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (2) DK2855496T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES2619412T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HR (2) HRP20170416T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (2) HUE032197T2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN2014KN02722A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LT (2) LT3202769T (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (2) PL2855496T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (2) PT3202769T (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RS (2) RS59725B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SI (2) SI3202769T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SM (2) SMT201700168T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (2) TWI599361B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2013176764A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013176764A1 (en) * 2012-05-24 2013-11-28 Phosplatin Therapeutics Llc Synthetic and purification methods for phosphaplatin compounds and uses thereof
CN109310663B (zh) * 2016-04-06 2022-05-31 弗斯普拉廷治疗有限公司 磷铂液体制剂
US10668080B2 (en) 2017-01-06 2020-06-02 Phosplatin Therapeutics Llc Phosphaplatin compounds as therapeutic agents for treatment of bone or blood cancers
EP3679046B1 (en) * 2017-09-08 2023-11-08 Promontory Therapeutics Inc. Phosphaplatin compounds as immuno-modulatory agents and therapeutic uses thereof
CN113861036B (zh) * 2021-11-08 2024-04-02 合肥工业大学 一种乙二胺高氯酸铜配合物的制备及用途
US11673904B1 (en) 2021-12-09 2023-06-13 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Low pressure process for synthesis of Pt(PF3)4 involving a soluble intermediate and storage of obtained Pt(PF3)4
CN119822568B (zh) * 2025-02-19 2025-08-19 扬州宏鑫环保科技有限公司 一种高效纯化水制备装置及制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234500A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
CA2530279A1 (en) 2003-06-27 2005-01-06 Akira Odani Bisphosphonate complexes
JP2009525273A (ja) * 2006-01-30 2009-07-09 プラットコー テクノロジーズ (プロプライエタリー) リミテッド 白金(ii)錯体の調製
JP5489988B2 (ja) * 2007-05-18 2014-05-14 Tti・エルビュー株式会社 有効成分の生体界面への改善された放出を確保する経皮送達装置
CN101801369B (zh) 2007-08-06 2012-09-19 俄亥俄大学 磷铂及其在治疗顺铂和卡铂耐药性癌中的用途
EP2575802B1 (en) * 2010-06-04 2016-11-16 Ohio University Phosphaplatins and their use for treatment of cancers
US9012669B2 (en) * 2011-10-05 2015-04-21 The University Of Houston System Efficient processes for large scale preparation of phosphaplatins antitumor agents
WO2013176764A1 (en) * 2012-05-24 2013-11-28 Phosplatin Therapeutics Llc Synthetic and purification methods for phosphaplatin compounds and uses thereof

Also Published As

Publication number Publication date
PL3202769T3 (pl) 2020-03-31
DK3202769T3 (da) 2019-10-28
RS55806B1 (sr) 2017-08-31
US8859796B1 (en) 2014-10-14
PL2855496T3 (pl) 2017-09-29
DK2855496T3 (en) 2017-03-27
EP3202769B1 (en) 2019-10-02
HUE046327T2 (hu) 2020-03-30
TWI653237B (zh) 2019-03-11
HRP20191904T1 (hr) 2020-01-24
HUE032197T2 (en) 2017-09-28
SI3202769T1 (sl) 2020-02-28
RS59725B1 (sr) 2020-01-31
HK1203202A1 (en) 2015-10-23
TW201741326A (zh) 2017-12-01
SMT201700168T1 (it) 2017-05-08
PT2855496T (pt) 2017-03-23
CY1118746T1 (el) 2018-03-07
CY1122316T1 (el) 2021-01-27
WO2013176764A1 (en) 2013-11-28
US20140024848A1 (en) 2014-01-23
US20140288321A1 (en) 2014-09-25
IN2014KN02722A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2015-05-08
JP2015523335A (ja) 2015-08-13
LT3202769T (lt) 2019-12-10
SMT201900617T1 (it) 2020-01-14
CN104540839A (zh) 2015-04-22
ES2751668T3 (es) 2020-04-01
CN106967124A (zh) 2017-07-21
US8846964B2 (en) 2014-09-30
EP2855496B1 (en) 2016-12-14
ES2619412T3 (es) 2017-06-26
CN106967124B (zh) 2020-03-06
SI2855496T1 (sl) 2017-04-26
JP5833795B2 (ja) 2015-12-16
EP3202769A1 (en) 2017-08-09
PT3202769T (pt) 2019-10-31
EP2855496A4 (en) 2015-04-08
TW201347765A (zh) 2013-12-01
CN104540839B (zh) 2017-02-22
EP2855496A1 (en) 2015-04-08
TWI599361B (zh) 2017-09-21
LT2855496T (lt) 2017-04-10

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