HRP20131023T1 - Soli bis(tio-hidrazid amida) za lijeäśenje raka - Google Patents

Soli bis(tio-hidrazid amida) za lijeäśenje raka Download PDF

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Publication number
HRP20131023T1
HRP20131023T1 HRP20131023TT HRP20131023T HRP20131023T1 HR P20131023 T1 HRP20131023 T1 HR P20131023T1 HR P20131023T T HRP20131023T T HR P20131023TT HR P20131023 T HRP20131023 T HR P20131023T HR P20131023 T1 HRP20131023 T1 HR P20131023T1
Authority
HR
Croatia
Prior art keywords
methyl
thio
compound
cancer
bis
Prior art date
Application number
HRP20131023TT
Other languages
English (en)
Croatian (hr)
Inventor
Elena Kostik
Farid Vaghefi
Guiqing Liang
Keizo Koya
Lijun Sun
Noriaki Tatsuta
Shoujun Chen
Takayo Inoue
Zhi-Qiang Xia
Original Assignee
Synta Pharmaceuticals Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synta Pharmaceuticals Corp. filed Critical Synta Pharmaceuticals Corp.
Publication of HRP20131023T1 publication Critical patent/HRP20131023T1/hr

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/38Amides of thiocarboxylic acids
    • C07C327/56Amides of thiocarboxylic acids having nitrogen atoms of thiocarboxamide groups further bound to another hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
HRP20131023TT 2004-06-23 2005-06-20 Soli bis(tio-hidrazid amida) za lijeäśenje raka HRP20131023T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58259604P 2004-06-23 2004-06-23
US68136805P 2005-05-16 2005-05-16
PCT/US2005/021642 WO2006009940A1 (en) 2004-06-23 2005-06-20 Bis(thio-hydrazide amide) salts for treatment of cancers

Publications (1)

Publication Number Publication Date
HRP20131023T1 true HRP20131023T1 (hr) 2013-12-06

Family

ID=34993190

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20131023TT HRP20131023T1 (hr) 2004-06-23 2005-06-20 Soli bis(tio-hidrazid amida) za lijeäśenje raka

Country Status (21)

Country Link
US (5) US7385084B2 (enExample)
EP (2) EP1781604B1 (enExample)
JP (1) JP5362986B2 (enExample)
KR (1) KR101313027B1 (enExample)
CN (1) CN1993318B (enExample)
AU (1) AU2005265202B2 (enExample)
BR (1) BRPI0512526A (enExample)
CA (1) CA2570698C (enExample)
DK (1) DK1781604T3 (enExample)
ES (1) ES2430373T3 (enExample)
HR (1) HRP20131023T1 (enExample)
IL (1) IL179632A (enExample)
ME (1) ME01644B (enExample)
NO (1) NO20070378L (enExample)
NZ (1) NZ552159A (enExample)
PL (1) PL1781604T3 (enExample)
PT (1) PT1781604E (enExample)
RS (1) RS52999B (enExample)
RU (2) RU2406722C2 (enExample)
TW (1) TWI389684B (enExample)
WO (1) WO2006009940A1 (enExample)

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US7579503B2 (en) 2009-08-25
NZ552159A (en) 2009-12-24
KR101313027B1 (ko) 2013-10-02
AU2005265202A1 (en) 2006-01-26
EP2305642A2 (en) 2011-04-06
EP2305642A3 (en) 2011-12-14
US20060135595A1 (en) 2006-06-22
US20090281172A1 (en) 2009-11-12
US7795313B2 (en) 2010-09-14
US20100324143A1 (en) 2010-12-23
RU2010145056A (ru) 2012-05-20
CA2570698C (en) 2013-11-19
TWI389684B (zh) 2013-03-21
HK1104526A1 (en) 2008-01-18
IL179632A0 (en) 2007-05-15
RS52999B (sr) 2014-02-28
US8461208B2 (en) 2013-06-11
PT1781604E (pt) 2013-10-15
RU2007101898A (ru) 2008-07-27
CA2570698A1 (en) 2006-01-26
US8048925B2 (en) 2011-11-01
KR20070029259A (ko) 2007-03-13
EP1781604B1 (en) 2013-08-07
CN1993318B (zh) 2012-10-03
EP1781604A1 (en) 2007-05-09
PL1781604T3 (pl) 2014-01-31
ES2430373T3 (es) 2013-11-20
JP5362986B2 (ja) 2013-12-11
DK1781604T3 (da) 2013-09-16
NO20070378L (no) 2007-03-16
CN1993318A (zh) 2007-07-04
US7385084B2 (en) 2008-06-10
ME01644B (me) 2014-09-20
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