HRP20120020T1 - Visokoosjetljivi imunoeseji i kompleti za određivanje peptida i proteina od biološkog interesa - Google Patents
Visokoosjetljivi imunoeseji i kompleti za određivanje peptida i proteina od biološkog interesa Download PDFInfo
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- HRP20120020T1 HRP20120020T1 HR20120020T HRP20120020T HRP20120020T1 HR P20120020 T1 HRP20120020 T1 HR P20120020T1 HR 20120020 T HR20120020 T HR 20120020T HR P20120020 T HRP20120020 T HR P20120020T HR P20120020 T1 HRP20120020 T1 HR P20120020T1
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- XBJKAZATRJBDCU-GUBZILKMSA-N Val-Pro-Ala Chemical compound CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(O)=O XBJKAZATRJBDCU-GUBZILKMSA-N 0.000 description 1
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- MIKHIIQMRFYVOR-RCWTZXSCSA-N Val-Pro-Thr Chemical compound C[C@H]([C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)N)O MIKHIIQMRFYVOR-RCWTZXSCSA-N 0.000 description 1
- UVHFONIHVHLDDQ-IFFSRLJSSA-N Val-Thr-Glu Chemical compound C[C@H]([C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](C(C)C)N)O UVHFONIHVHLDDQ-IFFSRLJSSA-N 0.000 description 1
- FEWOUVRMGWFWIH-ILZZQXMPSA-N amyloid-beta polypeptide 40 Chemical compound C([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(O)=O)[C@@H](C)CC)C(C)C)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(C)C)C1=CC=CC=C1 FEWOUVRMGWFWIH-ILZZQXMPSA-N 0.000 description 1
- 108010008355 arginyl-glutamine Proteins 0.000 description 1
- 108010001271 arginyl-glutamyl-arginine Proteins 0.000 description 1
- 108010062796 arginyllysine Proteins 0.000 description 1
- 108010060035 arginylproline Proteins 0.000 description 1
- 108010040443 aspartyl-aspartic acid Proteins 0.000 description 1
- 108010021908 aspartyl-aspartyl-glutamyl-aspartic acid Proteins 0.000 description 1
- 108010038633 aspartylglutamate Proteins 0.000 description 1
- 108010092854 aspartyllysine Proteins 0.000 description 1
- 108010016616 cysteinylglycine Proteins 0.000 description 1
- 108010049041 glutamylalanine Proteins 0.000 description 1
- VPZXBVLAVMBEQI-UHFFFAOYSA-N glycyl-DL-alpha-alanine Natural products OC(=O)C(C)NC(=O)CN VPZXBVLAVMBEQI-UHFFFAOYSA-N 0.000 description 1
- 108010025306 histidylleucine Proteins 0.000 description 1
- 108010085325 histidylproline Proteins 0.000 description 1
- 108010044374 isoleucyl-tyrosine Proteins 0.000 description 1
- 108010034529 leucyl-lysine Proteins 0.000 description 1
- 108010038320 lysylphenylalanine Proteins 0.000 description 1
- 108010017391 lysylvaline Proteins 0.000 description 1
- 108010031719 prolyl-serine Proteins 0.000 description 1
- 108010090894 prolylleucine Proteins 0.000 description 1
- 108010053725 prolylvaline Proteins 0.000 description 1
- 108010033670 threonyl-aspartyl-tyrosine Proteins 0.000 description 1
- 108010061238 threonyl-glycine Proteins 0.000 description 1
- 108010031491 threonyl-lysyl-glutamic acid Proteins 0.000 description 1
- 108010029384 tryptophyl-histidine Proteins 0.000 description 1
- 108010044292 tryptophyltyrosine Proteins 0.000 description 1
- 108010017949 tyrosyl-glycyl-glycine Proteins 0.000 description 1
- IBIDRSSEHFLGSD-UHFFFAOYSA-N valinyl-arginine Natural products CC(C)C(N)C(=O)NC(C(O)=O)CCCN=C(N)N IBIDRSSEHFLGSD-UHFFFAOYSA-N 0.000 description 1
- 108010015385 valyl-prolyl-proline Proteins 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07380227A EP2020602A1 (en) | 2007-08-02 | 2007-08-02 | High sensitivty immunoassays and kits for the determination of peptides and proteins of biological interest |
| PCT/EP2007/063334 WO2009015696A1 (en) | 2007-08-02 | 2007-12-05 | High sensitivty immunoassays and kits for the determination of peptides and proteins of biological interest |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120020T1 true HRP20120020T1 (hr) | 2012-03-31 |
Family
ID=38544110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20120020T HRP20120020T1 (hr) | 2007-08-02 | 2012-01-09 | Visokoosjetljivi imunoeseji i kompleti za određivanje peptida i proteina od biološkog interesa |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US20090035790A1 (ja) |
| EP (2) | EP2020602A1 (ja) |
| JP (1) | JP5657382B2 (ja) |
| KR (1) | KR101461538B1 (ja) |
| CN (1) | CN101861521B (ja) |
| AR (1) | AR064186A1 (ja) |
| AT (1) | ATE533059T1 (ja) |
| AU (1) | AU2007357025B2 (ja) |
| BR (1) | BRPI0721871A2 (ja) |
| CA (1) | CA2689024C (ja) |
| CL (1) | CL2007003513A1 (ja) |
| CY (1) | CY1112553T1 (ja) |
| DK (1) | DK2183599T3 (ja) |
| ES (1) | ES2377151T3 (ja) |
| HR (1) | HRP20120020T1 (ja) |
| IL (1) | IL202598A (ja) |
| MX (1) | MX2009013009A (ja) |
| PL (1) | PL2183599T3 (ja) |
| PT (1) | PT2183599E (ja) |
| RS (1) | RS52124B (ja) |
| RU (1) | RU2461837C2 (ja) |
| SI (1) | SI2183599T1 (ja) |
| WO (1) | WO2009015696A1 (ja) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013505438A (ja) * | 2009-09-18 | 2013-02-14 | プロビオドルグ エージー | アミロイドβペプチドの検出のための新規アッセイ |
| KR101531949B1 (ko) * | 2009-12-11 | 2015-06-26 | 아라클론 바이오테크, 에스.엘. | 아밀로이드 베타 펩티드의 개선된 검출 방법 및 시약 |
| CN102192985A (zh) * | 2010-03-18 | 2011-09-21 | 上海依科赛生物制品有限公司 | 一种人体β淀粉样蛋白试剂盒 |
| KR101352670B1 (ko) * | 2010-06-15 | 2014-01-17 | 울산대학교 산학협력단 | 알츠하이머 전구단백질 분비 펩타이드의 축적물을 포함하는 뇌 노화 감별 진단 마커 |
| KR101324415B1 (ko) * | 2010-07-26 | 2013-11-01 | 서울대학교산학협력단 | ＵＶ ｐｈｏｔｏｍｅｔｒｙ를 이용한 혈액 내의 고발현 단백질의 제거 또는 저발현 단백질의 회수 효율을 실시간으로 모니터하는 방법 |
| WO2012054333A2 (en) * | 2010-10-20 | 2012-04-26 | Merck Sharp & Dohme Corp. | Methods for identifying inhibitors of abeta42 oligomers |
| EP2511296A1 (en) * | 2011-04-12 | 2012-10-17 | Araclón Biotech, S. L. | Antibody, kit and method for determination of amyloid peptides |
| CN103827671B (zh) * | 2011-05-03 | 2017-05-03 | 联邦科学与工业研究组织 | 用于检测神经疾病的方法 |
| JP6231263B2 (ja) * | 2012-07-17 | 2017-11-15 | 株式会社島津製作所 | アフィニティ支持体及びそれを用いた物質の捕捉方法 |
| CN111770935A (zh) * | 2018-02-27 | 2020-10-13 | 株式会社岛津制作所 | 特异性识别APP669-x的N末端的抗体及免疫测定法 |
| CN113884683A (zh) * | 2020-07-30 | 2022-01-04 | 山东京济生物工程有限公司 | 一种快速检测Aβ42的双抗体夹心ELISA试剂盒 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811310A (en) * | 1986-09-30 | 1998-09-22 | Albert Einstein College Of Medicine Of Yeshiva Univ. | The Alz-50 monoclonal antibody and diagnostic assay for alzheimer's disease |
| AU7121191A (en) * | 1990-02-26 | 1991-10-10 | Albert Einstein College Of Medicine Of Yeshiva University | Diagnostic assay for alzheimer's disease |
| US7427392B1 (en) * | 1994-11-14 | 2008-09-23 | Elan Pharmaceuticals, Inc. | Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau |
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| JP2002519702A (ja) * | 1998-07-03 | 2002-07-02 | イノジェネティックス・ナムローゼ・フェンノートシャップ | 神経変性の分別診断 |
| AU2001269127A1 (en) * | 2000-07-06 | 2002-01-14 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | A novel app mutation associated with an unusual alzheimer's disease pathology |
| EP1371986A1 (en) * | 2002-06-06 | 2003-12-17 | ABETA GmbH | Diagnosis of Alzheimer's disease based on the hAbeta42:hAbeta40 ratio |
| PE20050627A1 (es) * | 2003-05-30 | 2005-08-10 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
| WO2006121656A2 (en) * | 2005-05-05 | 2006-11-16 | Merck & Co., Inc. | Peptide conjugate compositions and methods for the prevention and treatment of alzheimer's disease |
-
2007
- 2007-08-02 EP EP07380227A patent/EP2020602A1/en not_active Withdrawn
- 2007-12-05 MX MX2009013009A patent/MX2009013009A/es active IP Right Grant
- 2007-12-05 AU AU2007357025A patent/AU2007357025B2/en active Active
- 2007-12-05 EP EP07847829A patent/EP2183599B1/en active Active
- 2007-12-05 CL CL2007003513A patent/CL2007003513A1/es unknown
- 2007-12-05 RU RU2009143671/15A patent/RU2461837C2/ru active
- 2007-12-05 ES ES07847829T patent/ES2377151T3/es active Active
- 2007-12-05 RS RS20120046A patent/RS52124B/en unknown
- 2007-12-05 DK DK07847829.4T patent/DK2183599T3/da active
- 2007-12-05 PT PT07847829T patent/PT2183599E/pt unknown
- 2007-12-05 BR BRPI0721871-0A2A patent/BRPI0721871A2/pt not_active Application Discontinuation
- 2007-12-05 CA CA2689024A patent/CA2689024C/en active Active
- 2007-12-05 SI SI200730815T patent/SI2183599T1/sl unknown
- 2007-12-05 PL PL07847829T patent/PL2183599T3/pl unknown
- 2007-12-05 JP JP2010518506A patent/JP5657382B2/ja active Active
- 2007-12-05 CN CN200780053472.1A patent/CN101861521B/zh active Active
- 2007-12-05 WO PCT/EP2007/063334 patent/WO2009015696A1/en active Application Filing
- 2007-12-05 AT AT07847829T patent/ATE533059T1/de active
- 2007-12-05 KR KR1020107002425A patent/KR101461538B1/ko active IP Right Grant
- 2007-12-07 AR ARP070105484A patent/AR064186A1/es active IP Right Grant
- 2007-12-12 US US11/954,344 patent/US20090035790A1/en not_active Abandoned
-
2009
- 2009-12-08 IL IL202598A patent/IL202598A/en active IP Right Grant
-
2012
- 2012-01-09 HR HR20120020T patent/HRP20120020T1/hr unknown
- 2012-02-08 CY CY20121100131T patent/CY1112553T1/el unknown
-
2019
- 2019-02-22 US US16/282,943 patent/US20190178899A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CL2007003513A1 (es) | 2009-02-06 |
| PT2183599E (pt) | 2012-02-13 |
| EP2020602A1 (en) | 2009-02-04 |
| ATE533059T1 (de) | 2011-11-15 |
| AR064186A1 (es) | 2009-03-18 |
| AU2007357025A1 (en) | 2009-02-05 |
| MX2009013009A (es) | 2010-03-29 |
| JP5657382B2 (ja) | 2015-01-21 |
| JP2010535328A (ja) | 2010-11-18 |
| ES2377151T3 (es) | 2012-03-22 |
| KR20100046168A (ko) | 2010-05-06 |
| CN101861521A (zh) | 2010-10-13 |
| CA2689024A1 (en) | 2009-02-05 |
| PL2183599T3 (pl) | 2012-04-30 |
| RU2461837C2 (ru) | 2012-09-20 |
| CN101861521B (zh) | 2014-03-12 |
| WO2009015696A1 (en) | 2009-02-05 |
| RS52124B (en) | 2012-08-31 |
| SI2183599T1 (sl) | 2012-03-30 |
| CY1112553T1 (el) | 2016-02-10 |
| AU2007357025B2 (en) | 2014-10-23 |
| EP2183599A1 (en) | 2010-05-12 |
| BRPI0721871A2 (pt) | 2014-02-18 |
| DK2183599T3 (da) | 2012-02-27 |
| US20090035790A1 (en) | 2009-02-05 |
| IL202598A (en) | 2015-10-29 |
| CA2689024C (en) | 2015-02-24 |
| US20190178899A1 (en) | 2019-06-13 |
| EP2183599B1 (en) | 2011-11-09 |
| KR101461538B1 (ko) | 2014-11-14 |
| IL202598A0 (en) | 2010-06-30 |
| RU2009143671A (ru) | 2011-05-27 |
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