HRP20110899T1 - Protutumorsko cjepivo dobiveno iz normalnih, kemijski modificiranih stanica cd4+ - Google Patents
Protutumorsko cjepivo dobiveno iz normalnih, kemijski modificiranih stanica cd4+ Download PDFInfo
- Publication number
- HRP20110899T1 HRP20110899T1 HR20110899T HRP20110899T HRP20110899T1 HR P20110899 T1 HRP20110899 T1 HR P20110899T1 HR 20110899 T HR20110899 T HR 20110899T HR P20110899 T HRP20110899 T HR P20110899T HR P20110899 T1 HRP20110899 T1 HR P20110899T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation
- lymphocytes
- cells
- antigen
- antigens
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4267—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1121—Dendritic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0700058.1A GB0700058D0 (en) | 2007-01-03 | 2007-01-03 | Anti-tumor vaccine based on normal cells |
| PCT/EP2008/050050 WO2008081035A1 (en) | 2007-01-03 | 2008-01-03 | Anti-tumor vaccine derived from normal chemically modified cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20110899T1 true HRP20110899T1 (hr) | 2011-12-31 |
Family
ID=37759205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20110899T HRP20110899T1 (hr) | 2007-01-03 | 2008-01-03 | Protutumorsko cjepivo dobiveno iz normalnih, kemijski modificiranih stanica cd4+ |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10023839B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2102331B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5452231B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE522600T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008203730B2 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1112668T1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2102331T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2372713T3 (cg-RX-API-DMAC7.html) |
| GB (1) | GB0700058D0 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20110899T1 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2102331T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2102331E (cg-RX-API-DMAC7.html) |
| SI (1) | SI2102331T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008081035A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA011421B1 (ru) * | 2008-08-26 | 2009-02-27 | Петр Генриевич ЛОХОВ | Способ получения противоопухолевой вакцины |
| US8467973B2 (en) | 2009-07-28 | 2013-06-18 | Promising Future, Llc | Pairing processes for preparing alloreactive cytotoxic T cells |
| US8666674B2 (en) | 2009-07-28 | 2014-03-04 | Promising Future, Llc | Pairing processes for preparing reactive cytotoxic T cells |
| US9211321B2 (en) | 2009-10-27 | 2015-12-15 | Immunicum Ab | Method for proliferation of antigen-specific T cells |
| GB201013443D0 (en) | 2010-08-11 | 2010-09-22 | Cytovac As | Compositions and methods for producing dendritic cells |
| US10426740B1 (en) | 2010-08-18 | 2019-10-01 | Avm Biotechnology, Llc | Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues |
| EA201792642A1 (ru) | 2015-05-28 | 2018-10-31 | Кайт Фарма, Инк. | Способы диагностики для т-клеточной терапии |
| IL312426B1 (en) | 2015-05-28 | 2025-10-01 | Kite Pharma Inc | Methods for training patients for T-cell therapy |
| TW202521141A (zh) | 2015-10-20 | 2025-06-01 | 美商凱特製藥公司 | 製備用於ｔ細胞治療之ｔ細胞的方法 |
| UA128781C2 (uk) | 2016-04-01 | 2024-10-23 | Кайт Фарма, Інк. | Т-клітина, спосіб її отримання та застосування |
| CU20180121A7 (es) | 2016-04-01 | 2019-05-03 | Kite Pharma Inc | Receptores de antígenos quiméricos y células t |
| KR102522622B1 (ko) | 2016-04-01 | 2023-04-18 | 카이트 파마 인코포레이티드 | Bcma 결합 분자 및 그의 사용 방법 |
| WO2018152181A1 (en) | 2017-02-14 | 2018-08-23 | Kite Pharma, Inc. | Cd70 binding molecules and methods of use thereof |
| US20180280437A1 (en) | 2017-03-13 | 2018-10-04 | Kite Pharma, Inc. | Chimeric antigen receptors for melanoma and uses thereof |
| BR112019020214A2 (pt) | 2017-04-01 | 2020-04-22 | Avm Biotechnology Llc | substituição do pré-condicionamento citotóxico antes da imunoterapia celular |
| CN110494158A (zh) | 2017-04-03 | 2019-11-22 | 凯德药业股份有限公司 | 使用包含优化的多功能t细胞的嵌合受体t细胞进行治疗 |
| JOP20180042A1 (ar) | 2017-04-24 | 2019-01-30 | Kite Pharma Inc | نطاقات ربط مولد ضد متوافقة مع البشر وطرق الاستخدام |
| CN110662831A (zh) | 2017-05-26 | 2020-01-07 | 凯德药业股份有限公司 | 制备和使用胚胎间充质祖细胞的方法 |
| SG11202002327PA (en) | 2017-09-15 | 2020-04-29 | Kite Pharma Inc | Methods and systems for performing a patient-specific immunotherapy procedure with chain-of-custody and chain-of-identity biological sample tracking |
| WO2019060695A1 (en) | 2017-09-22 | 2019-03-28 | Kite Pharma, Inc. | CHIMERIC POLYPEPTIDES AND USES THEREOF |
| WO2019079564A1 (en) | 2017-10-18 | 2019-04-25 | Kite Pharma, Inc. | METHODS OF DELIVERY OF CHIMERIC ANTIGEN RECEPTOR IMMUNOTHERAPY |
| US11390655B2 (en) | 2017-11-16 | 2022-07-19 | Kite Pharma, Inc. | Modified chimeric antigen receptors and methods of use |
| TW201932593A (zh) | 2018-01-15 | 2019-08-16 | 美商輝瑞大藥廠 | 合併投與嵌合抗原受體之免疫療法與4-1bb促效劑的方法 |
| US12338459B2 (en) | 2018-02-02 | 2025-06-24 | Arizona Board Of Regents On Behalf Of Arizona State University | DNA-chimeric antigen receptor T cells for immunotherapy |
| KR102618231B1 (ko) | 2018-02-16 | 2023-12-28 | 카이트 파마 인코포레이티드 | 변형된 만능성 줄기 세포, 및 제조 및 사용 방법 |
| AU2019252944B2 (en) | 2018-04-12 | 2022-12-08 | Kite Pharma, Inc. | Chimeric receptor T cell treatment using characteristics of the tumor microenvironment |
| KR102734592B1 (ko) | 2018-06-01 | 2024-11-27 | 카이트 파마 인코포레이티드 | 키메라 항원 수용체 t 세포 요법 |
| US20210155941A1 (en) | 2018-06-22 | 2021-05-27 | Kite Pharma Eu B.V. | Compositions and methods for making engineered t cells |
| EP3830125A1 (en) | 2018-08-02 | 2021-06-09 | Kite Pharma, Inc. | Chimeric antigen receptor therapy t cell expansion kinetics and uses thereof |
| EP3488851A1 (en) | 2018-10-03 | 2019-05-29 | AVM Biotechnology, LLC | Immunoablative therapies |
| EP3632446B3 (en) | 2018-10-03 | 2024-01-24 | AVM Biotechnology, LLC | Immunoablative therapies |
| MX2021006968A (es) | 2018-12-12 | 2021-10-13 | Kite Pharma Inc | Antígeno quimérico y receptores de las células t, y métodos de uso. |
| WO2020208054A1 (en) | 2019-04-12 | 2020-10-15 | Cytovac A/S | Method for preparation of cancer/testis antigen-specific t-cells |
| CN118662516A (zh) | 2019-05-03 | 2024-09-20 | 凯德药业股份有限公司 | 施用嵌合抗原受体免疫疗法的方法 |
| CN114391021A (zh) | 2019-06-21 | 2022-04-22 | 凯德药业股份有限公司 | TGF-β受体和使用方法 |
| WO2021046134A1 (en) | 2019-09-03 | 2021-03-11 | Allogene Therapeutics, Inc. | Methods of preparing t cells for t cell therapy |
| WO2021260675A1 (en) | 2020-06-24 | 2021-12-30 | Yeda Research And Development Co. Ltd. | Agents for sensitizing solid tumors to treatment |
| IL299911A (en) | 2020-08-14 | 2023-03-01 | Kite Pharma Inc | Improving immune cell function |
| US12152251B2 (en) | 2020-08-25 | 2024-11-26 | Kite Pharma, Inc. | T cells with improved functionality |
| AU2021369507B2 (en) | 2020-10-28 | 2025-06-26 | Kite Pharma, Inc. | Flow cytometric method for characterization of t-cell impurities |
| CN116745319A (zh) | 2020-12-24 | 2023-09-12 | 凯德药业股份有限公司 | 前列腺癌嵌合抗原受体 |
| CA3207182A1 (en) | 2021-01-10 | 2022-07-14 | Kite Pharma, Inc. | T cell therapy |
| US20240076616A1 (en) | 2021-01-21 | 2024-03-07 | Cytovac A/S | Method for t-cell expansion and related medical applications |
| WO2022178243A1 (en) | 2021-02-20 | 2022-08-25 | Kite Pharma, Inc. | Gene markers for sellecting immunotherapies |
| IL305571A (en) | 2021-03-11 | 2023-10-01 | Kite Pharma Inc | Improving the function of immune system cells |
| US12337035B2 (en) | 2021-04-16 | 2025-06-24 | Kite Pharma, Inc. | TACI binding molecules |
| WO2022221126A1 (en) | 2021-04-16 | 2022-10-20 | Kite Pharma, Inc. | Methods and systems for scheduling a patient-specific immunotherapy procedure |
| AU2022274608B2 (en) | 2021-05-14 | 2025-12-11 | Kite Pharma, Inc. | Chimeric antigen receptor t cell therapy |
| KR20240013173A (ko) | 2021-05-24 | 2024-01-30 | 카이트 파마 인코포레이티드 | Nkg2d-기초 키메라 항원 수용체 |
| US20230020993A1 (en) | 2021-06-08 | 2023-01-19 | Kite Pharma, Inc. | Gpc3 binding molecules |
| WO2022269019A1 (en) | 2021-06-25 | 2022-12-29 | Cytovac A/S | Method for preparation of cytotoxic t lymphocytes with broad tumour-specific reactivity and characteristics of early differentiation cells |
| EP4363558A1 (en) | 2021-07-01 | 2024-05-08 | Kite Pharma, Inc. | Closed-system and method for autologous and allogeneic cell therapy manufacturing |
| JP2024525485A (ja) | 2021-07-02 | 2024-07-12 | カイト ファーマ インコーポレイテッド | 細胞療法適用において使用される遺伝子構築物由来の遺伝子産物におけるバリアントを特定するための方法 |
| US20230060292A1 (en) | 2021-07-26 | 2023-03-02 | Kite Pharma, Inc. | Split chimeric antigen receptors and methods of use |
| KR20240027077A (ko) | 2021-07-30 | 2024-02-29 | 카이트 파마 인코포레이티드 | 세포 요법-유도 독성의 모니터링 및 관리 |
| EP4419559A1 (en) | 2021-10-18 | 2024-08-28 | Kite Pharma, Inc. | Signaling domains for chimeric antigen receptors |
| JP2025508376A (ja) | 2022-02-15 | 2025-03-26 | カイト ファーマ インコーポレイテッド | 免疫療法由来の有害事象の予測 |
| WO2023247324A1 (en) | 2022-06-24 | 2023-12-28 | Cytovac A/S | Novel combination treatment with adoptive cellular therapy |
| WO2024044670A1 (en) | 2022-08-26 | 2024-02-29 | Kite Pharma, Inc. | Improving immune cell function |
| AU2023367198A1 (en) | 2022-10-28 | 2025-04-17 | Kite Pharma, Inc. | Improving efficacy and durable response of immunotherapy |
| US20240158869A1 (en) | 2022-10-28 | 2024-05-16 | Kite Pharma, Inc. | Factors for optimizing immunotherapy |
| US20240309428A1 (en) | 2023-03-17 | 2024-09-19 | Kite Pharma, Inc. | Impact of tumor microenvironment on efficacy of immunotherapy |
| US20250161361A1 (en) | 2023-11-01 | 2025-05-22 | Kite Pharma, Inc. | Factors for optimizing immunotherapy efficacy |
| WO2025174963A1 (en) | 2024-02-16 | 2025-08-21 | Kite Pharma, Inc. | Systems, methods, and kits for generating and administering engineered t cells and cd38 targeting compounds as a combination therapy |
| WO2025188561A1 (en) | 2024-03-04 | 2025-09-12 | Kite Pharma, Inc. | Predictive markers for immunotherapy |
| WO2025231376A1 (en) | 2024-05-03 | 2025-11-06 | Kite Pharma, Inc. | Chimeric receptors binding to cll-1 and methods of use thereof |
| US20250382383A1 (en) | 2024-05-31 | 2025-12-18 | Kite Pharma, Inc. | Tricistronic constructs for anti-gpc3 car |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003012085A1 (en) * | 2001-07-30 | 2003-02-13 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Antigen presenting cells, method for their preparation and their use for cancer vaccines |
-
2007
- 2007-01-03 GB GBGB0700058.1A patent/GB0700058D0/en not_active Ceased
-
2008
- 2008-01-03 SI SI200830447T patent/SI2102331T1/sl unknown
- 2008-01-03 HR HR20110899T patent/HRP20110899T1/hr unknown
- 2008-01-03 JP JP2009544412A patent/JP5452231B2/ja not_active Expired - Fee Related
- 2008-01-03 PL PL08701232T patent/PL2102331T3/pl unknown
- 2008-01-03 AU AU2008203730A patent/AU2008203730B2/en not_active Ceased
- 2008-01-03 ES ES08701232T patent/ES2372713T3/es active Active
- 2008-01-03 PT PT08701232T patent/PT2102331E/pt unknown
- 2008-01-03 AT AT08701232T patent/ATE522600T1/de active
- 2008-01-03 WO PCT/EP2008/050050 patent/WO2008081035A1/en not_active Ceased
- 2008-01-03 US US12/522,048 patent/US10023839B2/en active Active
- 2008-01-03 DK DK08701232.4T patent/DK2102331T3/da active
- 2008-01-03 EP EP08701232A patent/EP2102331B1/en active Active
-
2011
- 2011-11-17 CY CY20111101112T patent/CY1112668T1/el unknown
-
2017
- 2017-09-18 US US15/707,474 patent/US20180036397A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CY1112668T1 (el) | 2016-02-10 |
| PL2102331T3 (pl) | 2012-01-31 |
| DK2102331T3 (da) | 2011-10-17 |
| US20100092498A1 (en) | 2010-04-15 |
| EP2102331A1 (en) | 2009-09-23 |
| EP2102331B1 (en) | 2011-08-31 |
| ATE522600T1 (de) | 2011-09-15 |
| SI2102331T1 (sl) | 2012-01-31 |
| US20180036397A1 (en) | 2018-02-08 |
| US10023839B2 (en) | 2018-07-17 |
| JP2010514455A (ja) | 2010-05-06 |
| WO2008081035A1 (en) | 2008-07-10 |
| PT2102331E (pt) | 2011-12-19 |
| JP5452231B2 (ja) | 2014-03-26 |
| AU2008203730B2 (en) | 2013-11-07 |
| ES2372713T3 (es) | 2012-01-25 |
| AU2008203730A1 (en) | 2008-07-10 |
| GB0700058D0 (en) | 2007-02-07 |
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