ATE522600T1 - Anti-tumor impfstoff aus normalen chemisch modifizierten cd4+ zellen - Google Patents
Anti-tumor impfstoff aus normalen chemisch modifizierten cd4+ zellenInfo
- Publication number
- ATE522600T1 ATE522600T1 AT08701232T AT08701232T ATE522600T1 AT E522600 T1 ATE522600 T1 AT E522600T1 AT 08701232 T AT08701232 T AT 08701232T AT 08701232 T AT08701232 T AT 08701232T AT E522600 T1 ATE522600 T1 AT E522600T1
- Authority
- AT
- Austria
- Prior art keywords
- normal
- cells
- composition
- lymphoid cells
- lymphocytes
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 8
- 239000000427 antigen Substances 0.000 abstract 5
- 102000036639 antigens Human genes 0.000 abstract 5
- 108091007433 antigens Proteins 0.000 abstract 5
- 210000004698 lymphocyte Anatomy 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 4
- 201000011510 cancer Diseases 0.000 abstract 3
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 2
- 210000004443 dendritic cell Anatomy 0.000 abstract 2
- 230000028993 immune response Effects 0.000 abstract 2
- 230000035755 proliferation Effects 0.000 abstract 2
- 210000001550 testis Anatomy 0.000 abstract 2
- 230000035131 DNA demethylation Effects 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 210000005105 peripheral blood lymphocyte Anatomy 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4267—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0637—Immunosuppressive T lymphocytes, e.g. regulatory T cells or Treg
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1121—Dendritic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0700058.1A GB0700058D0 (en) | 2007-01-03 | 2007-01-03 | Anti-tumor vaccine based on normal cells |
| PCT/EP2008/050050 WO2008081035A1 (en) | 2007-01-03 | 2008-01-03 | Anti-tumor vaccine derived from normal chemically modified cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE522600T1 true ATE522600T1 (de) | 2011-09-15 |
Family
ID=37759205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08701232T ATE522600T1 (de) | 2007-01-03 | 2008-01-03 | Anti-tumor impfstoff aus normalen chemisch modifizierten cd4+ zellen |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10023839B2 (de) |
| EP (1) | EP2102331B1 (de) |
| JP (1) | JP5452231B2 (de) |
| AT (1) | ATE522600T1 (de) |
| AU (1) | AU2008203730B2 (de) |
| CY (1) | CY1112668T1 (de) |
| DK (1) | DK2102331T3 (de) |
| ES (1) | ES2372713T3 (de) |
| GB (1) | GB0700058D0 (de) |
| HR (1) | HRP20110899T1 (de) |
| PL (1) | PL2102331T3 (de) |
| PT (1) | PT2102331E (de) |
| SI (1) | SI2102331T1 (de) |
| WO (1) | WO2008081035A1 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA200801751A1 (ru) * | 2008-08-26 | 2009-02-27 | Петр Генриевич ЛОХОВ | Способ получения противоопухолевой вакцины |
| US8467973B2 (en) * | 2009-07-28 | 2013-06-18 | Promising Future, Llc | Pairing processes for preparing alloreactive cytotoxic T cells |
| US8666674B2 (en) | 2009-07-28 | 2014-03-04 | Promising Future, Llc | Pairing processes for preparing reactive cytotoxic T cells |
| BR112012009962A2 (pt) | 2009-10-27 | 2015-09-15 | Immunicum Ab | método para a proliferação de células tantígeno específicas. |
| GB201013443D0 (en) | 2010-08-11 | 2010-09-22 | Cytovac As | Compositions and methods for producing dendritic cells |
| US10426740B1 (en) | 2010-08-18 | 2019-10-01 | Avm Biotechnology, Llc | Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues |
| CN114344321A (zh) | 2015-05-28 | 2022-04-15 | 凯德药业股份有限公司 | 为t细胞疗法而调理患者的方法 |
| KR20230005428A (ko) | 2015-05-28 | 2023-01-09 | 카이트 파마 인코포레이티드 | T 세포 요법을 위한 진단 방법 |
| TW202521141A (zh) | 2015-10-20 | 2025-06-01 | 美商凱特製藥公司 | 製備用於ｔ細胞治療之ｔ細胞的方法 |
| PT3436030T (pt) | 2016-04-01 | 2022-11-18 | Amgen Inc | Recetores quiméricos e métodos para a sua utilização |
| SG11201808403SA (en) | 2016-04-01 | 2018-10-30 | Kite Pharma Inc | Bcma binding molecules and methods of use thereof |
| PL3436079T3 (pl) | 2016-04-01 | 2021-12-20 | Kite Pharma, Inc. | Antygen chimeryczny i receptory komórek t oraz sposoby ich stosowania |
| ES2900233T3 (es) | 2017-02-14 | 2022-03-16 | Kite Pharma Inc | Moléculas que se unen a CD70 y métodos de uso de las mismas |
| WO2018169922A2 (en) | 2017-03-13 | 2018-09-20 | Kite Pharma, Inc. | Chimeric antigen receptors for melanoma and uses thereof |
| KR102509006B1 (ko) | 2017-04-01 | 2023-03-13 | 에이브이엠 바이오테크놀로지, 엘엘씨 | 세포 면역치료요법 전 세포독성 사전컨디셔닝의 대체 |
| SG10201912624VA (en) | 2017-04-03 | 2020-02-27 | Kite Pharma Inc | Treatment using chimeric receptor t cells incorporating optimized polyfunctional t cells |
| JOP20180042A1 (ar) | 2017-04-24 | 2019-01-30 | Kite Pharma Inc | نطاقات ربط مولد ضد متوافقة مع البشر وطرق الاستخدام |
| WO2018218105A1 (en) | 2017-05-26 | 2018-11-29 | Kite Pharma, Inc. | Methods of making and using embryonic mesenchymal progenitor cells |
| US20200268860A1 (en) | 2017-09-15 | 2020-08-27 | Kite Pharma, Inc. | Methods and systems for performing a patient-specific immunotherapy procedure with chain-of-custody and chain-of-identity biological sample tracking |
| US20190092818A1 (en) | 2017-09-22 | 2019-03-28 | Kite Pharma, Inc. | Chimeric polypeptides and uses thereof |
| TW202510896A (zh) | 2017-10-18 | 2025-03-16 | 美商凱特製藥公司 | 投與嵌合抗原受體免疫療法之方法 |
| EP3710471A1 (de) | 2017-11-16 | 2020-09-23 | Kite Pharma, Inc. | Modifizierte chimäre antigenrezeptoren und verfahren zur verwendung |
| CN111867680A (zh) | 2018-01-15 | 2020-10-30 | 辉瑞大药厂 | 组合施用嵌合抗原受体免疫疗法与4-1bb激动剂的方法 |
| US12338459B2 (en) | 2018-02-02 | 2025-06-24 | Arizona Board Of Regents On Behalf Of Arizona State University | DNA-chimeric antigen receptor T cells for immunotherapy |
| SG11202007513PA (en) | 2018-02-16 | 2020-09-29 | Kite Pharma Inc | Modified pluripotent stem cells and methods of making and use |
| TWI723374B (zh) | 2018-04-12 | 2021-04-01 | 美商凱特製藥公司 | 利用腫瘤微環境之特性之嵌合受體t細胞治療 |
| CN112512537A (zh) | 2018-06-01 | 2021-03-16 | 凯德药业股份有限公司 | 嵌合抗原受体t细胞疗法 |
| EP3810780A1 (de) | 2018-06-22 | 2021-04-28 | Kite Pharma Eu B.V. | Zusammensetzungen und verfahren zur herstellung von gentechnisch veränderten t-zellen |
| JP2021531813A (ja) | 2018-08-02 | 2021-11-25 | カイト ファーマ インコーポレイテッドKite Pharma, Inc | キメラ抗原受容体療法のｔ細胞の増殖動態及びその使用 |
| EP3488851A1 (de) | 2018-10-03 | 2019-05-29 | AVM Biotechnology, LLC | Immunoablative therapien |
| EP3632446B3 (de) | 2018-10-03 | 2024-01-24 | AVM Biotechnology, LLC | Immunoablative therapien |
| MX2021006968A (es) | 2018-12-12 | 2021-10-13 | Kite Pharma Inc | Antígeno quimérico y receptores de las células t, y métodos de uso. |
| WO2020208054A1 (en) | 2019-04-12 | 2020-10-15 | Cytovac A/S | Method for preparation of cancer/testis antigen-specific t-cells |
| EP4249075A3 (de) | 2019-05-03 | 2023-11-08 | Kite Pharma, Inc. | Verfahren zur verabreichung einer chimären antigen-rezeptor-immuntherapie |
| US12109235B2 (en) | 2019-06-21 | 2024-10-08 | Kite Pharma, Inc. | TGF-beta receptors and methods of use |
| JP7785662B2 (ja) | 2019-09-03 | 2025-12-15 | アロジーン セラピューティクス，インコーポレイテッド | Ｔ細胞療法のためのｔ細胞の調製方法 |
| WO2021260675A1 (en) | 2020-06-24 | 2021-12-30 | Yeda Research And Development Co. Ltd. | Agents for sensitizing solid tumors to treatment |
| EP4196149A1 (de) | 2020-08-14 | 2023-06-21 | Kite Pharma, Inc. | Verbesserung der immunzellenfunktion |
| EP4501951A3 (de) | 2020-08-25 | 2025-04-30 | Kite Pharma, Inc. | T-zellen mit verbesserter funktionalität |
| WO2022093925A1 (en) | 2020-10-28 | 2022-05-05 | Kite Pharma, Inc. | Flow cytometric method for characterization of t-cell impurities |
| EP4267623A1 (de) | 2020-12-24 | 2023-11-01 | Kite Pharma, Inc. | Chimäre prostatakrebs-antigenrezeptoren |
| KR20230129485A (ko) | 2021-01-10 | 2023-09-08 | 카이트 파마 인코포레이티드 | T 세포 요법 |
| EP4281545A1 (de) | 2021-01-21 | 2023-11-29 | CytoVac A/S | Verfahren zur t-zellexpansion und zugehörige medizinische anwendungen |
| EP4294950A1 (de) | 2021-02-20 | 2023-12-27 | Kite Pharma, Inc. | Genmarker zur auswahl von immuntherapien |
| WO2022192439A1 (en) | 2021-03-11 | 2022-09-15 | Kite Pharma, Inc. | Improving immune cell function |
| US20220336087A1 (en) | 2021-04-16 | 2022-10-20 | Kite Pharma, Inc. | Methods and systems for scheduling a patient-specific immunotherapy procedure |
| US12337035B2 (en) | 2021-04-16 | 2025-06-24 | Kite Pharma, Inc. | TACI binding molecules |
| EP4337227A2 (de) | 2021-05-14 | 2024-03-20 | Kite Pharma, Inc. | Chimäre antigenrezeptor-t-zelltherapie |
| CA3221231A1 (en) | 2021-05-24 | 2022-12-01 | Kite Pharma, Inc. | Chimeric antigen receptor |
| EP4352102A1 (de) | 2021-06-08 | 2024-04-17 | Kite Pharma, Inc. | Gpc3-bindende moleküle |
| WO2022269019A1 (en) | 2021-06-25 | 2022-12-29 | Cytovac A/S | Method for preparation of cytotoxic t lymphocytes with broad tumour-specific reactivity and characteristics of early differentiation cells |
| WO2023278553A1 (en) | 2021-07-01 | 2023-01-05 | Kite Pharma, Inc. | Closed-system and method for autologous and allogeneic cell therapy manufacturing |
| CN117597738A (zh) | 2021-07-02 | 2024-02-23 | 凯德药业股份有限公司 | 一种鉴定来自用于细胞治疗应用的基因构建体的基因产物中的变体的方法 |
| US20230060292A1 (en) | 2021-07-26 | 2023-03-02 | Kite Pharma, Inc. | Split chimeric antigen receptors and methods of use |
| EP4377694A1 (de) | 2021-07-30 | 2024-06-05 | Kite Pharma, Inc. | Überwachung und verwaltung von durch zelltherapie induzierten toxizitäten |
| JP2024538116A (ja) | 2021-10-18 | 2024-10-18 | カイト ファーマ インコーポレイテッド | キメラ抗原受容体のシグナル伝達ドメイン |
| KR20240144434A (ko) | 2022-02-15 | 2024-10-02 | 카이트 파마 인코포레이티드 | 면역요법으로 인한 유해사례 예측 |
| WO2023247324A1 (en) | 2022-06-24 | 2023-12-28 | Cytovac A/S | Novel combination treatment with adoptive cellular therapy |
| EP4577234A1 (de) | 2022-08-26 | 2025-07-02 | Kite Pharma, Inc. | Verbesserung der immunzellenfunktion |
| TWI882495B (zh) | 2022-10-28 | 2025-05-01 | 美商凱特製藥公司 | 用於將免疫療法最佳化之因素 |
| US20240165160A1 (en) | 2022-10-28 | 2024-05-23 | Kite Pharma, Inc. | Efficacy and durable response of immunotherapy |
| CN120917153A (zh) | 2023-03-17 | 2025-11-07 | 凯德药业股份有限公司 | 肿瘤微环境对免疫疗法疗效的影响 |
| US20250161361A1 (en) | 2023-11-01 | 2025-05-22 | Kite Pharma, Inc. | Factors for optimizing immunotherapy efficacy |
| US20250262300A1 (en) | 2024-02-16 | 2025-08-21 | Kite Pharma, Inc. | Systems, methods, and kits for generating and administering engineered t cells and cd38 targeting compounds as a combination therapy |
| US20250290154A1 (en) | 2024-03-04 | 2025-09-18 | Kite Pharma, Inc. | Predictive markers for immunotherapy |
| WO2025231376A1 (en) | 2024-05-03 | 2025-11-06 | Kite Pharma, Inc. | Chimeric receptors binding to cll-1 and methods of use thereof |
| WO2025250819A1 (en) | 2024-05-31 | 2025-12-04 | Kite Pharma, Inc. | Tricistronic constructs for anti-gpc3 car |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003012085A1 (en) * | 2001-07-30 | 2003-02-13 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Antigen presenting cells, method for their preparation and their use for cancer vaccines |
-
2007
- 2007-01-03 GB GBGB0700058.1A patent/GB0700058D0/en not_active Ceased
-
2008
- 2008-01-03 SI SI200830447T patent/SI2102331T1/sl unknown
- 2008-01-03 EP EP08701232A patent/EP2102331B1/de active Active
- 2008-01-03 PL PL08701232T patent/PL2102331T3/pl unknown
- 2008-01-03 WO PCT/EP2008/050050 patent/WO2008081035A1/en not_active Ceased
- 2008-01-03 HR HR20110899T patent/HRP20110899T1/hr unknown
- 2008-01-03 AU AU2008203730A patent/AU2008203730B2/en not_active Ceased
- 2008-01-03 JP JP2009544412A patent/JP5452231B2/ja not_active Expired - Fee Related
- 2008-01-03 US US12/522,048 patent/US10023839B2/en active Active
- 2008-01-03 ES ES08701232T patent/ES2372713T3/es active Active
- 2008-01-03 AT AT08701232T patent/ATE522600T1/de active
- 2008-01-03 DK DK08701232.4T patent/DK2102331T3/da active
- 2008-01-03 PT PT08701232T patent/PT2102331E/pt unknown
-
2011
- 2011-11-17 CY CY20111101112T patent/CY1112668T1/el unknown
-
2017
- 2017-09-18 US US15/707,474 patent/US20180036397A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US10023839B2 (en) | 2018-07-17 |
| PT2102331E (pt) | 2011-12-19 |
| AU2008203730B2 (en) | 2013-11-07 |
| JP5452231B2 (ja) | 2014-03-26 |
| EP2102331A1 (de) | 2009-09-23 |
| JP2010514455A (ja) | 2010-05-06 |
| HRP20110899T1 (hr) | 2011-12-31 |
| AU2008203730A1 (en) | 2008-07-10 |
| US20100092498A1 (en) | 2010-04-15 |
| PL2102331T3 (pl) | 2012-01-31 |
| WO2008081035A1 (en) | 2008-07-10 |
| SI2102331T1 (sl) | 2012-01-31 |
| CY1112668T1 (el) | 2016-02-10 |
| GB0700058D0 (en) | 2007-02-07 |
| ES2372713T3 (es) | 2012-01-25 |
| US20180036397A1 (en) | 2018-02-08 |
| DK2102331T3 (da) | 2011-10-17 |
| EP2102331B1 (de) | 2011-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE522600T1 (de) | Anti-tumor impfstoff aus normalen chemisch modifizierten cd4+ zellen | |
| Zom et al. | Efficient induction of antitumor immunity by synthetic toll-like receptor ligand–peptide conjugates | |
| JP2010514455A5 (de) | ||
| EA202190587A3 (ru) | Новые пептиды и комбинации пептидов для применения в иммунотерапии гепатоклеточной карциномы (гкк) и других видов рака | |
| EA201071297A1 (ru) | Новые и действенные пептиды мнс ii класса, полученные из сурвивина | |
| MX338294B (es) | Novedoso inmunotratamiento contra diversos tumores incluidos tumores neuronales y cerebrales. | |
| BR112012023692A2 (pt) | imunoterapias contra vários tumores, incluindo câncer gastrointestinal e gástrico | |
| CL2019003423A1 (es) | Nuevos péptidos (seq id n°378), combinaciones de péptidos y soportes para el uso en el tratamiento inmunoterapéutico de varios tipos de cáncer. (divisional solicitud 201800545) | |
| MX2010001086A (es) | Nueva inmunoterapia contra tumores neuronales y cerebrales. | |
| CY1114912T1 (el) | Εμβολιο για την προληψη της υποτροπης του καρκινου του μαστου | |
| NZ616304A (en) | Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses | |
| UA111738C2 (uk) | Спосіб активної клітинної імунотерапії раку шляхом застосування пухлинних клітин, знищених за допомогою високого гідростатичного тиску, і дендритних клітин | |
| WO2019098759A3 (ko) | 형질전환된 인간세포 및 이의 용도 | |
| CL2017002407A1 (es) | Péptidos y combinación de péptidos novedosos para su uso en inmunoterapia contra diversos tumores | |
| JP2018522880A5 (de) | ||
| Masuko et al. | Artificially synthesized helper/killer-hybrid epitope long peptide (H/K-HELP): preparation and immunological analysis of vaccine efficacy | |
| MX2020011793A (es) | Nuevos peptidos y nueva combinacion de peptidos para el uso en la inmunoterapia contra el carcinoma hepatocelular (chc) y otros tipos de cancer. | |
| Izgi et al. | Evaluation of two different adjuvants with immunogenic uroplakin 3A-derived peptide for their ability to evoke an immune response in mice | |
| NZ762110A (en) | Compounds, compositions, kits, and methods for activating immune cells and/or an immune system response | |
| EA202190465A3 (ru) | Новые пептиды и комбинации пептидов для применения в иммунотерапии нхл и других видов рака |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 2102331 Country of ref document: EP |