HRP20110024T1 - Antibakterijski derivati kvinolina - Google Patents
Antibakterijski derivati kvinolina Download PDFInfo
- Publication number
- HRP20110024T1 HRP20110024T1 HR20110024T HRP20110024T HRP20110024T1 HR P20110024 T1 HRP20110024 T1 HR P20110024T1 HR 20110024 T HR20110024 T HR 20110024T HR P20110024 T HRP20110024 T HR P20110024T HR P20110024 T1 HRP20110024 T1 HR P20110024T1
- Authority
- HR
- Croatia
- Prior art keywords
- alkyl
- aryl
- het
- mono
- compound according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06125545 | 2006-12-06 | ||
| PCT/EP2007/063319 WO2008068272A2 (en) | 2006-12-06 | 2007-12-04 | Antibacterial quinoline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20110024T1 true HRP20110024T1 (hr) | 2011-04-30 |
Family
ID=38048032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20110024T HRP20110024T1 (hr) | 2006-12-06 | 2007-12-04 | Antibakterijski derivati kvinolina |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US20100063026A1 (OSRAM) |
| EP (1) | EP2099761B1 (OSRAM) |
| JP (1) | JP5466013B2 (OSRAM) |
| KR (1) | KR101553600B1 (OSRAM) |
| CN (1) | CN101547906B (OSRAM) |
| AP (1) | AP2477A (OSRAM) |
| AR (1) | AR064148A1 (OSRAM) |
| AT (1) | ATE486061T1 (OSRAM) |
| AU (1) | AU2007328892B2 (OSRAM) |
| BR (1) | BRPI0719915A2 (OSRAM) |
| CA (1) | CA2668558C (OSRAM) |
| CL (1) | CL2007003518A1 (OSRAM) |
| CY (1) | CY1112027T1 (OSRAM) |
| DE (1) | DE602007010182D1 (OSRAM) |
| DK (1) | DK2099761T3 (OSRAM) |
| EA (1) | EA016760B1 (OSRAM) |
| ES (1) | ES2354755T3 (OSRAM) |
| HR (1) | HRP20110024T1 (OSRAM) |
| IL (1) | IL199082A (OSRAM) |
| JO (1) | JO2683B1 (OSRAM) |
| ME (1) | ME01230B (OSRAM) |
| MX (1) | MX2009005906A (OSRAM) |
| MY (1) | MY145940A (OSRAM) |
| NO (1) | NO341984B1 (OSRAM) |
| NZ (1) | NZ576862A (OSRAM) |
| PL (1) | PL2099761T3 (OSRAM) |
| PT (1) | PT2099761E (OSRAM) |
| RS (1) | RS51582B (OSRAM) |
| SI (1) | SI2099761T1 (OSRAM) |
| TW (1) | TWI487526B (OSRAM) |
| UA (1) | UA101307C2 (OSRAM) |
| WO (1) | WO2008068272A2 (OSRAM) |
| ZA (1) | ZA200903949B (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2970B1 (en) * | 2006-12-06 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
| CN104254528B (zh) * | 2012-04-27 | 2017-06-06 | 詹森药业有限公司 | 抗菌的喹啉衍生物 |
| US9133167B2 (en) | 2012-04-27 | 2015-09-15 | Janssen Pharmaceutica Nv | Antibacterial quinoline derivatives |
| WO2023178035A1 (en) | 2022-03-14 | 2023-09-21 | Slap Pharmaceuticals Llc | Multicyclic compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001503411A (ja) * | 1996-10-28 | 2001-03-13 | ディパートメント オブ ジ アーミー，ユー．エス．ガバメント | 抗生物質耐性感染症の処置のための化合物、組成物および方法 |
| RS52431B (sr) * | 2002-07-25 | 2013-02-28 | Janssen Pharmaceutica N.V. | Derivati hinolina i njihova upotreba kao mikobakterijskih inhibitora |
| UA86952C2 (uk) * | 2004-01-23 | 2009-06-10 | Янссен Фармацевтика Н.В. | Похідні хіноліну та їх застосування як мікобактеріальних інгібіторів |
| CN1910154B (zh) * | 2004-01-29 | 2011-08-17 | 詹森药业有限公司 | 用作分枝杆菌抑制剂的喹啉衍生物 |
| ES2306146T3 (es) * | 2004-05-28 | 2008-11-01 | Janssen Pharmaceutica Nv | Uso de derivados de quinolina sustituidos para el tratamiento de enfermedades micobacterianas resistentes a farmacos. |
| EE05394B1 (et) * | 2004-12-24 | 2011-04-15 | Janssen Pharmaceutica N.V. | Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis |
| CA2528849C (en) * | 2005-06-08 | 2014-01-14 | Janssen Pharmaceutica N.V. | Quinoline derivatives as antibacterial agents |
| JO2752B1 (en) * | 2005-06-28 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
| AP2547A (en) * | 2005-06-28 | 2012-12-26 | Janssen Pharmaceutica Nv | Quinoline derivatives as antibacterial agents |
| JO2952B1 (en) * | 2005-08-03 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
| JO2855B1 (en) * | 2005-08-03 | 2015-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
| JO2837B1 (en) * | 2005-08-03 | 2014-09-15 | جانسن فارمسيتكا ان في | Quinoline derivatives acting as antibacterial agents |
-
2007
- 2007-12-02 JO JO2007510A patent/JO2683B1/en active
- 2007-12-04 ME MEP-2011-10A patent/ME01230B/me unknown
- 2007-12-04 UA UAA200904443A patent/UA101307C2/ru unknown
- 2007-12-04 AP AP2009004873A patent/AP2477A/xx active
- 2007-12-04 BR BRPI0719915-5A2A patent/BRPI0719915A2/pt not_active Application Discontinuation
- 2007-12-04 NZ NZ576862A patent/NZ576862A/en not_active IP Right Cessation
- 2007-12-04 SI SI200730471T patent/SI2099761T1/sl unknown
- 2007-12-04 MY MYPI20092287A patent/MY145940A/en unknown
- 2007-12-04 US US12/516,420 patent/US20100063026A1/en not_active Abandoned
- 2007-12-04 WO PCT/EP2007/063319 patent/WO2008068272A2/en not_active Ceased
- 2007-12-04 RS RS20110019A patent/RS51582B/sr unknown
- 2007-12-04 DK DK07847817.9T patent/DK2099761T3/da active
- 2007-12-04 ES ES07847817T patent/ES2354755T3/es active Active
- 2007-12-04 KR KR1020097013568A patent/KR101553600B1/ko not_active Expired - Fee Related
- 2007-12-04 CN CN200780045128.8A patent/CN101547906B/zh not_active Expired - Fee Related
- 2007-12-04 HR HR20110024T patent/HRP20110024T1/hr unknown
- 2007-12-04 JP JP2009539742A patent/JP5466013B2/ja not_active Expired - Fee Related
- 2007-12-04 AT AT07847817T patent/ATE486061T1/de active
- 2007-12-04 DE DE602007010182T patent/DE602007010182D1/de active Active
- 2007-12-04 PL PL07847817T patent/PL2099761T3/pl unknown
- 2007-12-04 MX MX2009005906A patent/MX2009005906A/es active IP Right Grant
- 2007-12-04 AU AU2007328892A patent/AU2007328892B2/en not_active Ceased
- 2007-12-04 CA CA2668558A patent/CA2668558C/en active Active
- 2007-12-04 EP EP07847817A patent/EP2099761B1/en active Active
- 2007-12-04 PT PT07847817T patent/PT2099761E/pt unknown
- 2007-12-04 EA EA200970537A patent/EA016760B1/ru unknown
- 2007-12-05 CL CL200703518A patent/CL2007003518A1/es unknown
- 2007-12-05 TW TW096146212A patent/TWI487526B/zh not_active IP Right Cessation
- 2007-12-05 AR ARP070105441A patent/AR064148A1/es unknown
-
2009
- 2009-06-02 IL IL199082A patent/IL199082A/en active IP Right Grant
- 2009-06-05 ZA ZA200903949A patent/ZA200903949B/xx unknown
- 2009-07-06 NO NO20092541A patent/NO341984B1/no unknown
-
2011
- 2011-01-27 CY CY20111100087T patent/CY1112027T1/el unknown
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