HRP20100641T1 - Imidazolidinonilaminopirimidinski spojevi za liječenje raka - Google Patents

Imidazolidinonilaminopirimidinski spojevi za liječenje raka Download PDF

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Publication number
HRP20100641T1
HRP20100641T1 HR20100641T HRP20100641T HRP20100641T1 HR P20100641 T1 HRP20100641 T1 HR P20100641T1 HR 20100641 T HR20100641 T HR 20100641T HR P20100641 T HRP20100641 T HR P20100641T HR P20100641 T1 HRP20100641 T1 HR P20100641T1
Authority
HR
Croatia
Prior art keywords
ethyl
thiophen
benzo
ylamino
imidazolidin
Prior art date
Application number
HR20100641T
Other languages
English (en)
Croatian (hr)
Inventor
Li Hong-Yu
Burns Brooks Harold
Z. Crich Joyce
Robert Henry James
Scott Sawyer Jason
Wang Yan
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of HRP20100641T1 publication Critical patent/HRP20100641T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
HR20100641T 2006-12-21 2007-12-11 Imidazolidinonilaminopirimidinski spojevi za liječenje raka HRP20100641T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87132206P 2006-12-21 2006-12-21
PCT/US2007/087046 WO2008076705A1 (en) 2006-12-21 2007-12-11 Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer

Publications (1)

Publication Number Publication Date
HRP20100641T1 true HRP20100641T1 (hr) 2010-12-31

Family

ID=39185681

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100641T HRP20100641T1 (hr) 2006-12-21 2007-12-11 Imidazolidinonilaminopirimidinski spojevi za liječenje raka

Country Status (21)

Country Link
US (1) US8063212B2 (enExample)
EP (1) EP2125794B1 (enExample)
JP (1) JP2010513553A (enExample)
KR (1) KR101080594B1 (enExample)
CN (1) CN101568539B (enExample)
AT (1) ATE485291T1 (enExample)
AU (1) AU2007334040B2 (enExample)
BR (1) BRPI0720607A2 (enExample)
CA (1) CA2673564A1 (enExample)
CY (1) CY1110950T1 (enExample)
DE (1) DE602007010041D1 (enExample)
DK (1) DK2125794T3 (enExample)
EA (1) EA016178B1 (enExample)
ES (1) ES2351371T3 (enExample)
HR (1) HRP20100641T1 (enExample)
MX (1) MX2009006635A (enExample)
PL (1) PL2125794T3 (enExample)
PT (1) PT2125794E (enExample)
RS (1) RS51526B (enExample)
SI (1) SI2125794T1 (enExample)
WO (1) WO2008076705A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE479680T1 (de) 2006-12-21 2010-09-15 Lilly Co Eli Imidazolidinonylaminopyrimidinverbindungen zur behandlung von krebs
TW200908981A (en) * 2007-05-16 2009-03-01 Lilly Co Eli Triazolyl aminopyrimidine compounds
CN104781257A (zh) 2012-06-14 2015-07-15 第一三共株式会社 哌啶基吡唑并吡啶衍生物
EP2929883A1 (en) 2014-04-08 2015-10-14 Institut Pasteur Pyrazole derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors
KR102693614B1 (ko) 2022-04-04 2024-08-08 경희대학교 산학협력단 나프탈렌-2-일알킬기가 치환된 이미다졸리움 유도체 및 이를 유효성분으로 포함하는 암 치료용 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929726A (en) 1988-02-09 1990-05-29 Georgia State University Foundation, Inc. Novel diazines and their method of preparation
WO2004063192A1 (en) 2003-01-10 2004-07-29 Pharmacopeia Drug Discovery, Inc. Imidazolyl pyrimidine derivatives useful as il-8 receptor modulators
GB0308466D0 (en) 2003-04-11 2003-05-21 Novartis Ag Organic compounds
CN101115749B (zh) * 2004-12-17 2011-06-22 安姆根有限公司 氨基嘧啶化合物和使用方法
TW200800201A (en) * 2005-11-18 2008-01-01 Lilly Co Eli Pyrimidinyl benzothiophene compounds
EP2001480A4 (en) * 2006-03-31 2011-06-15 Abbott Lab Indazole CONNECTIONS
ATE479680T1 (de) 2006-12-21 2010-09-15 Lilly Co Eli Imidazolidinonylaminopyrimidinverbindungen zur behandlung von krebs
EP2155735A2 (en) 2007-05-16 2010-02-24 Eli Lilly And Company Triazolyl aminopyrimidine compounds
TW200908981A (en) 2007-05-16 2009-03-01 Lilly Co Eli Triazolyl aminopyrimidine compounds

Also Published As

Publication number Publication date
CN101568539B (zh) 2012-04-25
EP2125794A1 (en) 2009-12-02
MX2009006635A (es) 2009-06-30
PT2125794E (pt) 2011-01-10
CY1110950T1 (el) 2015-06-10
BRPI0720607A2 (pt) 2014-04-08
RS51526B (sr) 2011-06-30
US20100081641A1 (en) 2010-04-01
ATE485291T1 (de) 2010-11-15
SI2125794T1 (sl) 2011-02-28
KR20090086111A (ko) 2009-08-10
EP2125794B1 (en) 2010-10-20
DE602007010041D1 (de) 2010-12-02
CN101568539A (zh) 2009-10-28
JP2010513553A (ja) 2010-04-30
EA200970616A1 (ru) 2009-10-30
DK2125794T3 (da) 2011-01-24
AU2007334040A1 (en) 2008-06-26
KR101080594B1 (ko) 2011-11-04
AU2007334040B2 (en) 2012-02-16
ES2351371T3 (es) 2011-02-03
EA016178B1 (ru) 2012-02-28
US8063212B2 (en) 2011-11-22
CA2673564A1 (en) 2008-06-26
PL2125794T3 (pl) 2011-04-29
WO2008076705A1 (en) 2008-06-26

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