PL2125794T3 - Imidazolidynonylo aminopirymidynowe związki do leczenia raka - Google Patents

Imidazolidynonylo aminopirymidynowe związki do leczenia raka

Info

Publication number
PL2125794T3
PL2125794T3 PL07855060T PL07855060T PL2125794T3 PL 2125794 T3 PL2125794 T3 PL 2125794T3 PL 07855060 T PL07855060 T PL 07855060T PL 07855060 T PL07855060 T PL 07855060T PL 2125794 T3 PL2125794 T3 PL 2125794T3
Authority
PL
Poland
Prior art keywords
aminomethyl
hydrogen
cancer
treatment
halo
Prior art date
Application number
PL07855060T
Other languages
English (en)
Inventor
Hong-Yu Li
Harold Burns Brooks
Joyce Z Crich
James Robert Henry
Jason Scott Sawyer
Yan Wang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL2125794T3 publication Critical patent/PL2125794T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
PL07855060T 2006-12-21 2007-12-11 Imidazolidynonylo aminopirymidynowe związki do leczenia raka PL2125794T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87132206P 2006-12-21 2006-12-21
EP07855060A EP2125794B1 (en) 2006-12-21 2007-12-11 Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
PCT/US2007/087046 WO2008076705A1 (en) 2006-12-21 2007-12-11 Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer

Publications (1)

Publication Number Publication Date
PL2125794T3 true PL2125794T3 (pl) 2011-04-29

Family

ID=39185681

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07855060T PL2125794T3 (pl) 2006-12-21 2007-12-11 Imidazolidynonylo aminopirymidynowe związki do leczenia raka

Country Status (21)

Country Link
US (1) US8063212B2 (pl)
EP (1) EP2125794B1 (pl)
JP (1) JP2010513553A (pl)
KR (1) KR101080594B1 (pl)
CN (1) CN101568539B (pl)
AT (1) ATE485291T1 (pl)
AU (1) AU2007334040B2 (pl)
BR (1) BRPI0720607A2 (pl)
CA (1) CA2673564A1 (pl)
CY (1) CY1110950T1 (pl)
DE (1) DE602007010041D1 (pl)
DK (1) DK2125794T3 (pl)
EA (1) EA016178B1 (pl)
ES (1) ES2351371T3 (pl)
HR (1) HRP20100641T1 (pl)
MX (1) MX2009006635A (pl)
PL (1) PL2125794T3 (pl)
PT (1) PT2125794E (pl)
RS (1) RS51526B (pl)
SI (1) SI2125794T1 (pl)
WO (1) WO2008076705A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2125793B1 (en) 2006-12-21 2010-09-01 Eli Lilly & Company Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
CA2691997A1 (en) * 2007-05-16 2008-11-27 Eli Lilly And Company Triazolyl aminopyrimidine compounds
WO2013187462A1 (ja) 2012-06-14 2013-12-19 第一三共株式会社 ピペリジニルピラゾロピリジン誘導体
EP2929883A1 (en) 2014-04-08 2015-10-14 Institut Pasteur Pyrazole derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors
KR20230142927A (ko) 2022-04-04 2023-10-11 경희대학교 산학협력단 나프탈렌-2-일알킬기가 치환된 이미다졸리움 유도체 및 이를 유효성분으로 포함하는 암 치료용 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929726A (en) 1988-02-09 1990-05-29 Georgia State University Foundation, Inc. Novel diazines and their method of preparation
WO2004063192A1 (en) * 2003-01-10 2004-07-29 Pharmacopeia Drug Discovery, Inc. Imidazolyl pyrimidine derivatives useful as il-8 receptor modulators
GB0308466D0 (en) 2003-04-11 2003-05-21 Novartis Ag Organic compounds
JP4932735B2 (ja) 2004-12-17 2012-05-16 アムジエン・インコーポレーテツド アミノピリミジン化合物および使用方法
TW200800201A (en) * 2005-11-18 2008-01-01 Lilly Co Eli Pyrimidinyl benzothiophene compounds
EP2001480A4 (en) * 2006-03-31 2011-06-15 Abbott Lab Indazole CONNECTIONS
EP2125793B1 (en) 2006-12-21 2010-09-01 Eli Lilly & Company Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer
CA2691997A1 (en) 2007-05-16 2008-11-27 Eli Lilly And Company Triazolyl aminopyrimidine compounds
AR066472A1 (es) 2007-05-16 2009-08-19 Lilly Co Eli Compuesto de triazolil aminopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento

Also Published As

Publication number Publication date
CN101568539A (zh) 2009-10-28
EA200970616A1 (ru) 2009-10-30
DK2125794T3 (da) 2011-01-24
CN101568539B (zh) 2012-04-25
CA2673564A1 (en) 2008-06-26
AU2007334040A1 (en) 2008-06-26
KR101080594B1 (ko) 2011-11-04
ES2351371T3 (es) 2011-02-03
CY1110950T1 (el) 2015-06-10
US8063212B2 (en) 2011-11-22
EP2125794A1 (en) 2009-12-02
DE602007010041D1 (de) 2010-12-02
AU2007334040B2 (en) 2012-02-16
EP2125794B1 (en) 2010-10-20
JP2010513553A (ja) 2010-04-30
WO2008076705A1 (en) 2008-06-26
MX2009006635A (es) 2009-06-30
EA016178B1 (ru) 2012-02-28
BRPI0720607A2 (pt) 2014-04-08
HRP20100641T1 (hr) 2010-12-31
KR20090086111A (ko) 2009-08-10
ATE485291T1 (de) 2010-11-15
PT2125794E (pt) 2011-01-10
US20100081641A1 (en) 2010-04-01
RS51526B (en) 2011-06-30
SI2125794T1 (sl) 2011-02-28

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